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The map label for this gene is mtgA [H]

Identifier: 145299143

GI number: 145299143

Start: 2306629

End: 2307399

Strand: Direct

Name: mtgA [H]

Synonym: ASA_2171

Alternate gene names: 145299143

Gene position: 2306629-2307399 (Clockwise)

Preceding gene: 145299142

Following gene: 145299144

Centisome position: 49.05

GC content: 61.35

Gene sequence:

>771_bases
ATGGTTGCCCCAATAATTCCGGATCCCGATGATCTGCGTCCCCGCTATTATGCCCCCGAGCCGGCACGTCCGGCTCTGGG
ACGGCGCATGCTGAGCTGGCTCGGCAAGCTGCTGGCGGCAGTCCTGCTCAGCTCCATCGTCTCGGTGGTGCTGCTGCGCT
TCATCGATCCCCCCATGTGGACCTGGCGCATCGAACGGGCCCTGTTTCCGCCCGCCAAGATAGCCGTGGTCAAGCATGAC
TGGGTGCCCATAGATCGTATTTCGCGGGAACTGCAACTGGCGGTGATCGCCGCAGAGGATCAGCGCTTTGCCGACCATAG
CGGCTTTGACATGGATGCCATCAGCTCGGCACTCAAGCACAACCAGCGCAGCAAGCGGGTACGTGGCGCCAGCACGCTGA
GCCAGCAGACAGCCAAGAATCTCTTCATGTGGAGCGATCGCAGCTTCCTGCGCAAGGGGATCGAGGCCTGGTTTACCCTG
CTGATGGAGCTGGGTTGGGACAAATCCCGCATCCTCGAGGTCTATCTCAATATCGTGGAGTTCGGCCCCGGCATCTATGG
CGCCGAGGCCGCCGCCAAGCACTATTTTGGCAAATCGGCCGCCCGCTTGACTCGTTACGAGGCTTCTCTGCTGGCTGCCG
CCCTGCCCAATCCCTGGCGCTATCGGGTCCAGCCTCCCTCCCCCTATGTTCAGCAACGCTCGGCCTGGATCCGTCGCCAG
ATGGGTCAACTTGGCCAGGCTACCCTCAACAAGGTATACAAGGACGATTAA

Upstream 100 bases:

>100_bases
AGATCTGGATCGGGCTTGGTAATGCCGAACAAGAATATGAGCACCTGTTTGCCCGCATGCTGCTCTCCCGCCGTGTTGAC
GAGAAGTTCTGCCACATCGA

Downstream 100 bases:

>100_bases
GGATCGGGCACAGAGCATGCCCGGATAGCCGTACATCGCCCCTGAGCACATCAGAGTCATCTATCAGGGATCGGGGTCAG
CAGGCAATGTCTCTGCCGGC

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MVAPIIPDPDDLRPRYYAPEPARPALGRRMLSWLGKLLAAVLLSSIVSVVLLRFIDPPMWTWRIERALFPPAKIAVVKHD
WVPIDRISRELQLAVIAAEDQRFADHSGFDMDAISSALKHNQRSKRVRGASTLSQQTAKNLFMWSDRSFLRKGIEAWFTL
LMELGWDKSRILEVYLNIVEFGPGIYGAEAAAKHYFGKSAARLTRYEASLLAAALPNPWRYRVQPPSPYVQQRSAWIRRQ
MGQLGQATLNKVYKDD

Sequences:

>Translated_256_residues
MVAPIIPDPDDLRPRYYAPEPARPALGRRMLSWLGKLLAAVLLSSIVSVVLLRFIDPPMWTWRIERALFPPAKIAVVKHD
WVPIDRISRELQLAVIAAEDQRFADHSGFDMDAISSALKHNQRSKRVRGASTLSQQTAKNLFMWSDRSFLRKGIEAWFTL
LMELGWDKSRILEVYLNIVEFGPGIYGAEAAAKHYFGKSAARLTRYEASLLAAALPNPWRYRVQPPSPYVQQRSAWIRRQ
MGQLGQATLNKVYKDD
>Mature_256_residues
MVAPIIPDPDDLRPRYYAPEPARPALGRRMLSWLGKLLAAVLLSSIVSVVLLRFIDPPMWTWRIERALFPPAKIAVVKHD
WVPIDRISRELQLAVIAAEDQRFADHSGFDMDAISSALKHNQRSKRVRGASTLSQQTAKNLFMWSDRSFLRKGIEAWFTL
LMELGWDKSRILEVYLNIVEFGPGIYGAEAAAKHYFGKSAARLTRYEASLLAAALPNPWRYRVQPPSPYVQQRSAWIRRQ
MGQLGQATLNKVYKDD

Specific function: Cell wall formation [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family [H]

Homologues:

Organism=Escherichia coli, GI1789601, Length=182, Percent_Identity=58.2417582417582, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1786343, Length=137, Percent_Identity=39.4160583941606, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082258, Length=136, Percent_Identity=39.7058823529412, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788867, Length=142, Percent_Identity=35.2112676056338, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001264
- InterPro:   IPR011812 [H]

Pfam domain/function: PF00912 Transgly [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 29215; Mature: 29215

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPIIPDPDDLRPRYYAPEPARPALGRRMLSWLGKLLAAVLLSSIVSVVLLRFIDPPMW
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
TWRIERALFPPAKIAVVKHDWVPIDRISRELQLAVIAAEDQRFADHSGFDMDAISSALKH
HHHHHHHHCCCHHEEEEECCCCCHHHHHHHHEEEEEEECCHHHCCCCCCCHHHHHHHHHH
NQRSKRVRGASTLSQQTAKNLFMWSDRSFLRKGIEAWFTLLMELGWDKSRILEVYLNIVE
HHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FGPGIYGAEAAAKHYFGKSAARLTRYEASLLAAALPNPWRYRVQPPSPYVQQRSAWIRRQ
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHH
MGQLGQATLNKVYKDD
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVAPIIPDPDDLRPRYYAPEPARPALGRRMLSWLGKLLAAVLLSSIVSVVLLRFIDPPMW
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
TWRIERALFPPAKIAVVKHDWVPIDRISRELQLAVIAAEDQRFADHSGFDMDAISSALKH
HHHHHHHHCCCHHEEEEECCCCCHHHHHHHHEEEEEEECCHHHCCCCCCCHHHHHHHHHH
NQRSKRVRGASTLSQQTAKNLFMWSDRSFLRKGIEAWFTLLMELGWDKSRILEVYLNIVE
HHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FGPGIYGAEAAAKHYFGKSAARLTRYEASLLAAALPNPWRYRVQPPSPYVQQRSAWIRRQ
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHH
MGQLGQATLNKVYKDD
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA