Click here to switch to the map view.

The map label for this gene is idhA [H]

Identifier: 145297051

GI number: 145297051

Start: 3267113

End: 3268120

Strand: Direct

Name: idhA [H]

Synonym: cgR_2947

Alternate gene names: 145297051

Gene position: 3267113-3268120 (Clockwise)

Preceding gene: 145297050

Following gene: 145297052

Centisome position: 98.58

GC content: 56.05

Gene sequence:

>1008_bases
ATGACTCTTCGTATCGCCCTTTTCGGCGCTGGCCGCATCGGTCACGTCCACGCTGCCAACATTGCTGCAAACCCTGATCT
TGAACTCGTTGTTATCGCCGATCCTTTCATTGAAGGCGCACAGCGTTTGGCAGAAGCCAATGGGGCAGAAGCGGTTGCAT
CACCAGATGAGGTGTTCGCCCGCGATGATATCGATGGCATCGTGATCGGTTCACCAACCAGCACCCACGTTGATCTGATC
ACCCGCGCCGTGGAACGTGGCATTCCTGCACTGTGCGAAAAACCCATTGATTTAGACATTGAAATGGTGCGTGCCTGCAA
AGAGAAGATCGGCGACGGCGCTTCCAAGGTGATGCTGGGATTCAACCGACGCTTCGATCCTTCTTTCGCTGCCATCAATG
CGCGAGTGGCAAACCAGGAGATCGGCAACCTGGAGCAGTTGGTGATCATCAGCCGCGATCCAGCGCCCGCACCGAAGGAC
TACATCGCAGGTTCCGGTGGAATCTTCCGCGATATGACCATCCACGATCTGGATATGGCGCGTTTCTTTGTGCCCAATAT
CGTGGAAGTGACTGCAACCGGCGCCAATGTTTTCAGCCAGGAAATCGCGGAGTTCAATGACTACGACCAGGTTATCGTCA
CCCTTCGTGGCTCAAAGGGCGAGTTGATCAACATCGTGAACTCCCGCCACTGCTCCTACGGCTACGACCAGCGACTTGAG
GCTTTCGGCTCTAAGGGCATGCTCGCCGCCGACAACATCAGGCCCACCACGGTGCGCAAGCACAATGCGGAAAGCACCGA
GCAGGCAGATCCGATTTTCAACTTCTTCCTCGAGCGCTACGACGCCGCTTACAAGGCAGAGCTCGCAACTTTTGCTCAAG
GAATCCGCGACGGCCAAGGCTTCTCACCAAACTTCGAGGACGGCGTCATCGCCCTTGAACTAGCGAATGCATGCCTTGAA
TCAGCTCAAACCGGCCGCACCGTCACCCTCAACCCTGCCAACGTTTAG

Upstream 100 bases:

>100_bases
GAAGGGCTGCAACGTGCTTTCGACACCACCATCGCAGCGTTTGAACAAGCTGCTCATCTCGCCCCCTCCACTAACTGATC
TTTGAAAGGCTGAAAAACTC

Downstream 100 bases:

>100_bases
TCAACGTCTAGTTAATGCCTAAGGAGAAAACCTCATGAAAAACATCACCATCGGAATGGTCGGCGTCGGCCGCATTGGCC
GCATGCACGTCACCAACATG

Product: hypothetical protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI-dehydrogenase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTLRIALFGAGRIGHVHAANIAANPDLELVVIADPFIEGAQRLAEANGAEAVASPDEVFARDDIDGIVIGSPTSTHVDLI
TRAVERGIPALCEKPIDLDIEMVRACKEKIGDGASKVMLGFNRRFDPSFAAINARVANQEIGNLEQLVIISRDPAPAPKD
YIAGSGGIFRDMTIHDLDMARFFVPNIVEVTATGANVFSQEIAEFNDYDQVIVTLRGSKGELINIVNSRHCSYGYDQRLE
AFGSKGMLAADNIRPTTVRKHNAESTEQADPIFNFFLERYDAAYKAELATFAQGIRDGQGFSPNFEDGVIALELANACLE
SAQTGRTVTLNPANV

Sequences:

>Translated_335_residues
MTLRIALFGAGRIGHVHAANIAANPDLELVVIADPFIEGAQRLAEANGAEAVASPDEVFARDDIDGIVIGSPTSTHVDLI
TRAVERGIPALCEKPIDLDIEMVRACKEKIGDGASKVMLGFNRRFDPSFAAINARVANQEIGNLEQLVIISRDPAPAPKD
YIAGSGGIFRDMTIHDLDMARFFVPNIVEVTATGANVFSQEIAEFNDYDQVIVTLRGSKGELINIVNSRHCSYGYDQRLE
AFGSKGMLAADNIRPTTVRKHNAESTEQADPIFNFFLERYDAAYKAELATFAQGIRDGQGFSPNFEDGVIALELANACLE
SAQTGRTVTLNPANV
>Mature_334_residues
TLRIALFGAGRIGHVHAANIAANPDLELVVIADPFIEGAQRLAEANGAEAVASPDEVFARDDIDGIVIGSPTSTHVDLIT
RAVERGIPALCEKPIDLDIEMVRACKEKIGDGASKVMLGFNRRFDPSFAAINARVANQEIGNLEQLVIISRDPAPAPKDY
IAGSGGIFRDMTIHDLDMARFFVPNIVEVTATGANVFSQEIAEFNDYDQVIVTLRGSKGELINIVNSRHCSYGYDQRLEA
FGSKGMLAADNIRPTTVRKHNAESTEQADPIFNFFLERYDAAYKAELATFAQGIRDGQGFSPNFEDGVIALELANACLES
AQTGRTVTLNPANV

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=228, Percent_Identity=25.8771929824561, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 36225; Mature: 36094

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRIALFGAGRIGHVHAANIAANPDLELVVIADPFIEGAQRLAEANGAEAVASPDEVFA
CEEEEEEEECCCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCCCCCHHHHH
RDDIDGIVIGSPTSTHVDLITRAVERGIPALCEKPIDLDIEMVRACKEKIGDGASKVMLG
CCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHCCCHHHEEEC
FNRRFDPSFAAINARVANQEIGNLEQLVIISRDPAPAPKDYIAGSGGIFRDMTIHDLDMA
CCCCCCCCHHEEEHHHHHHHHCCCEEEEEEECCCCCCCHHHCCCCCCCEECCEEHHHHHH
RFFVPNIVEVTATGANVFSQEIAEFNDYDQVIVTLRGSKGELINIVNSRHCSYGYDQRLE
HHHCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHH
AFGSKGMLAADNIRPTTVRKHNAESTEQADPIFNFFLERYDAAYKAELATFAQGIRDGQG
HHCCCCCEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC
FSPNFEDGVIALELANACLESAQTGRTVTLNPANV
CCCCCCCCEEHHHHHHHHHHHHCCCCEEEECCCCC
>Mature Secondary Structure 
TLRIALFGAGRIGHVHAANIAANPDLELVVIADPFIEGAQRLAEANGAEAVASPDEVFA
EEEEEEEECCCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCCCCCHHHHH
RDDIDGIVIGSPTSTHVDLITRAVERGIPALCEKPIDLDIEMVRACKEKIGDGASKVMLG
CCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHCCCHHHEEEC
FNRRFDPSFAAINARVANQEIGNLEQLVIISRDPAPAPKDYIAGSGGIFRDMTIHDLDMA
CCCCCCCCHHEEEHHHHHHHHCCCEEEEEEECCCCCCCHHHCCCCCCCEECCEEHHHHHH
RFFVPNIVEVTATGANVFSQEIAEFNDYDQVIVTLRGSKGELINIVNSRHCSYGYDQRLE
HHHCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHH
AFGSKGMLAADNIRPTTVRKHNAESTEQADPIFNFFLERYDAAYKAELATFAQGIRDGQG
HHCCCCCEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC
FSPNFEDGVIALELANACLESAQTGRTVTLNPANV
CCCCCCCCEEHHHHHHHHHHHHCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9802033; 11481431 [H]