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The map label for this gene is trpD

Identifier: 145297021

GI number: 145297021

Start: 3238575

End: 3239621

Strand: Direct

Name: trpD

Synonym: cgR_2918

Alternate gene names: 145297021

Gene position: 3238575-3239621 (Clockwise)

Preceding gene: 145297020

Following gene: 145297022

Centisome position: 97.72

GC content: 58.93

Gene sequence:

>1047_bases
ATGACTTCTCCAGCAACACTGAAAGTTCTCAACGCCTACTTGGATAACCCCACTCCAACCCTGGAGGAGGCAATTGAGGT
GTTCACCCCGCTGACCGTGGGTGAATACGATGACGTGCATATCGCGGCGCTGCTTGCCACCATCCGTACTCGCGGTGAGC
AGTTCGCTGATATTGCCGGCGCTGCCAAGGCATTCCTCGCGGCGGCTCGTCCGTTCCCGATTACTGGCGCAGGTTTGCTA
GATTCCGCTGGTACTGGTGGCGACGGTGCCAACACCATCAACATCACCACCGGCGCTTCCCTGATCGCAGCATCCGGTGG
AGTGAAGCTGGTTAAGCACGGCAACCGTTCAGTGAGCTCCAAGTCCGGTTCCGCCGATGTGCTGGAGGCGCTGAATATTC
CTTTGGGCCTTGATGTGGATCGTGCTGTGAAGTGGTTCGAAGCGTCCAACTTCACCTTCCTGTTCGCACCTGCGTACAAC
CCTGCGATTGCGCATGTGCAGCCGGTTCGCCAGGCGCTGAAATTCCCCACCATCTTCAACACGCTTGGACCATTGCTGTC
CCCGGCGCGCCCGGAGCGTCAGATCATGGGCGTGGCCAATGCCAATCATGGACAGCTCATCGCCGAGGTCTTCCGCGAGC
TGGGCCGTACACGCGCGCTTGTTGTGCATGGCGCAGGCACCGATGAGATCGCAGTCCACGGCACCACCTTGGTGTGGGAG
CTTAAAGAAGACGGCACCATCGAGCATTACACCATCGAGCCTGAGGACCTTGGCCTTGGCCGCTACACCCTTGAGGATCT
CGTAGGTGGCCTCGGCACTGAGAATGCCGAAGCTATGCGCGCTACTTTCGCGGGCACCGGCCCTGATGCACACCGTGATG
CGTTGGCTGCGTCCGCAGGTGCGATGTTCTACCTCAACGGCGATGTCGACTCCTTGAAGGATGGTGCACAAAAGGCGCTT
TCCTTGCTTGCCGACGGCACCACCCAGGCATGGTTGGCCAAGCACGAAGAGATCGATTACTCAGAAAAGGAGTCTTCCAA
TGACTAG

Upstream 100 bases:

>100_bases
CAGTTTCACCCTGAGTCAGTGCTGAGCCCAACGGGTCCTGTCATTTTGTCCCGCTGTGTCGAACAACTTCTCGCGAACTA
ATTAAAAAAGGATTTGATTC

Downstream 100 bases:

>100_bases
TAATAATCTGCCCACGGTGTTGGAAAGCATCGTCGAGGGTCGTCGCGGACACCTGGAGGAAATTCGCGCTCGCATCGCTC
ACGTGGATGTAGATGCGCTT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTSPATLKVLNAYLDNPTPTLEEAIEVFTPLTVGEYDDVHIAALLATIRTRGEQFADIAGAAKAFLAAARPFPITGAGLL
DSAGTGGDGANTINITTGASLIAASGGVKLVKHGNRSVSSKSGSADVLEALNIPLGLDVDRAVKWFEASNFTFLFAPAYN
PAIAHVQPVRQALKFPTIFNTLGPLLSPARPERQIMGVANANHGQLIAEVFRELGRTRALVVHGAGTDEIAVHGTTLVWE
LKEDGTIEHYTIEPEDLGLGRYTLEDLVGGLGTENAEAMRATFAGTGPDAHRDALAASAGAMFYLNGDVDSLKDGAQKAL
SLLADGTTQAWLAKHEEIDYSEKESSND

Sequences:

>Translated_348_residues
MTSPATLKVLNAYLDNPTPTLEEAIEVFTPLTVGEYDDVHIAALLATIRTRGEQFADIAGAAKAFLAAARPFPITGAGLL
DSAGTGGDGANTINITTGASLIAASGGVKLVKHGNRSVSSKSGSADVLEALNIPLGLDVDRAVKWFEASNFTFLFAPAYN
PAIAHVQPVRQALKFPTIFNTLGPLLSPARPERQIMGVANANHGQLIAEVFRELGRTRALVVHGAGTDEIAVHGTTLVWE
LKEDGTIEHYTIEPEDLGLGRYTLEDLVGGLGTENAEAMRATFAGTGPDAHRDALAASAGAMFYLNGDVDSLKDGAQKAL
SLLADGTTQAWLAKHEEIDYSEKESSND
>Mature_347_residues
TSPATLKVLNAYLDNPTPTLEEAIEVFTPLTVGEYDDVHIAALLATIRTRGEQFADIAGAAKAFLAAARPFPITGAGLLD
SAGTGGDGANTINITTGASLIAASGGVKLVKHGNRSVSSKSGSADVLEALNIPLGLDVDRAVKWFEASNFTFLFAPAYNP
AIAHVQPVRQALKFPTIFNTLGPLLSPARPERQIMGVANANHGQLIAEVFRELGRTRALVVHGAGTDEIAVHGTTLVWEL
KEDGTIEHYTIEPEDLGLGRYTLEDLVGGLGTENAEAMRATFAGTGPDAHRDALAASAGAMFYLNGDVDSLKDGAQKALS
LLADGTTQAWLAKHEEIDYSEKESSND

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=319, Percent_Identity=41.692789968652, Blast_Score=206, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6320561, Length=268, Percent_Identity=30.5970149253731, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_CORGB (A4QI74)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001139842.1
- ProteinModelPortal:   A4QI74
- SMR:   A4QI74
- STRING:   A4QI74
- GeneID:   4993425
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_2918
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36633; Mature: 36502

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPATLKVLNAYLDNPTPTLEEAIEVFTPLTVGEYDDVHIAALLATIRTRGEQFADIAG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
AAKAFLAAARPFPITGAGLLDSAGTGGDGANTINITTGASLIAASGGVKLVKHGNRSVSS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCEEEEECCCCCCCC
KSGSADVLEALNIPLGLDVDRAVKWFEASNFTFLFAPAYNPAIAHVQPVRQALKFPTIFN
CCCCHHHHHHHCCCCCCCHHHHHHHEECCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHH
TLGPLLSPARPERQIMGVANANHGQLIAEVFRELGRTRALVVHGAGTDEIAVHGTTLVWE
HHHHHCCCCCCCHHEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEECEEEEEE
LKEDGTIEHYTIEPEDLGLGRYTLEDLVGGLGTENAEAMRATFAGTGPDAHRDALAASAG
ECCCCCEEEEEECHHHCCCCCEEHHHHHCCCCCCCHHHHHHEECCCCCCHHHHHHHHCCC
AMFYLNGDVDSLKDGAQKALSLLADGTTQAWLAKHEEIDYSEKESSND
EEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TSPATLKVLNAYLDNPTPTLEEAIEVFTPLTVGEYDDVHIAALLATIRTRGEQFADIAG
CCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
AAKAFLAAARPFPITGAGLLDSAGTGGDGANTINITTGASLIAASGGVKLVKHGNRSVSS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCEEEEECCCCCCCC
KSGSADVLEALNIPLGLDVDRAVKWFEASNFTFLFAPAYNPAIAHVQPVRQALKFPTIFN
CCCCHHHHHHHCCCCCCCHHHHHHHEECCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHH
TLGPLLSPARPERQIMGVANANHGQLIAEVFRELGRTRALVVHGAGTDEIAVHGTTLVWE
HHHHHCCCCCCCHHEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEECEEEEEE
LKEDGTIEHYTIEPEDLGLGRYTLEDLVGGLGTENAEAMRATFAGTGPDAHRDALAASAG
ECCCCCEEEEEECHHHCCCCCEEHHHHHCCCCCCCHHHHHHEECCCCCCHHHHHHHHCCC
AMFYLNGDVDSLKDGAQKALSLLADGTTQAWLAKHEEIDYSEKESSND
EEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA