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The map label for this gene is yusP [H]

Identifier: 145296942

GI number: 145296942

Start: 3154526

End: 3155680

Strand: Reverse

Name: yusP [H]

Synonym: cgR_2842

Alternate gene names: 145296942

Gene position: 3155680-3154526 (Counterclockwise)

Preceding gene: 145296944

Following gene: 145296941

Centisome position: 95.22

GC content: 54.55

Gene sequence:

>1155_bases
ATGATGGATTCGTATTCCAAGGCCGCGATGGGGTCGGTGCTCATGGCTCTCCAGTTTGCCAGCTATTGCATCATGCACAA
AATATGTACCATACACATAATGTCATCGAGCCCTCCCGAATCAGCCACACCACAGATCAAATACGGCCTGCTGGTGGTCA
CTCTCGCCTCAGCTGGTATCACTGTTTCCCTAGCGCAGACCCTGGTTATTCCGATCATTGGTCGGTTGCCCGAGATCTTC
AACACCACGGCTGCTAATGCCTCTTGGATCATTACTGTGACGCTGCTGGTGGGCGCAGTGGCGACTCCTGTGATGGGCAG
GCTTGCAGATATGTACGGCAAGAAAAAGATGATGCTCATCTCGCTTGTCCCGTTCGTTCTTGGATCAGTGATCTGCGCTG
TGTCGGCGGATTTGATTCCGATGATCATCGGCCGTGGTTTTCAGGGGCTTGGTTCTGGCCTGATTCCTCTTGGCATTTCT
CTCATGCATGATTTGTTGCCCCGGGAGAAAGCAGGGTCTGCCATTGCTTTGATGAGTTCTTCCATGGGCATTGGCGGTGC
ACTCGGTCTACCGCTAGCTGCTGCTATTGCCCAGTTTGCGTCCTGGCGGGTGCTGTTCTGGTTCACCGCTCTGGTAGCGC
TTACAGTTGGCGCGGTCATTTGGAAGGCGATTCCTGCTAGACCCAGGATCGTGAGGAGTGGCGGCTTTGATTATTTCGGT
ACTCTCGGCCTTGCAATGGGAATTATCGCATTGTTGCTCGCGGTGTCCAAGGGATCAGAATGGGGCTGGAGAAGTGCCCT
GACCATTGGGTTATTCGTGGCAGCGCTGGTGATTTTGGTGAGTTGGGGCTGGTTCGAAACCCGTCAGAAATCCCCTTTGA
TTGATCTGCGCACCACTATTCGGGCGACCGTGTTGATGACAAATATTGCGTCCATCCTCATCGGTTTCACCATGTATGGA
ATGAATCTGATCCTGCCGCAGGTTATGCAGCTGCCTGTAATTCTGGGCTACGGTCTAGGCCGTGTGGAACAAGTCGTGTG
GTGGGCGTTGGGCCTCGGCGAAAGCCCTGCGTGCGGCATCGCGGGCTTGGCCGCCGTGACGGTTGTTCTGCTATCATGGC
TGCGTGATGGAGACCTCGCCGATGAATCGCAGTGA

Upstream 100 bases:

>100_bases
ACGTAACTGGAGCAGCGTGAGTAGGTTGTAGCCGCTGGAATCGAGGACGCCAGCATTCGTACCTGCTTGGCCGGTGTATT
GATTCCGGTGACGGGCGAAG

Downstream 100 bases:

>100_bases
TCGCGCAGCTGTCGCTCTTGTGACGGGTGCGGGGCGGGGAATCGGAGCGGCGATCGCGCGGGCGCTGTCCGATCTCGATT
ATGTGGTTGTCGTTACAGAC

Product: hypothetical protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MMDSYSKAAMGSVLMALQFASYCIMHKICTIHIMSSSPPESATPQIKYGLLVVTLASAGITVSLAQTLVIPIIGRLPEIF
NTTAANASWIITVTLLVGAVATPVMGRLADMYGKKKMMLISLVPFVLGSVICAVSADLIPMIIGRGFQGLGSGLIPLGIS
LMHDLLPREKAGSAIALMSSSMGIGGALGLPLAAAIAQFASWRVLFWFTALVALTVGAVIWKAIPARPRIVRSGGFDYFG
TLGLAMGIIALLLAVSKGSEWGWRSALTIGLFVAALVILVSWGWFETRQKSPLIDLRTTIRATVLMTNIASILIGFTMYG
MNLILPQVMQLPVILGYGLGRVEQVVWWALGLGESPACGIAGLAAVTVVLLSWLRDGDLADESQ

Sequences:

>Translated_384_residues
MMDSYSKAAMGSVLMALQFASYCIMHKICTIHIMSSSPPESATPQIKYGLLVVTLASAGITVSLAQTLVIPIIGRLPEIF
NTTAANASWIITVTLLVGAVATPVMGRLADMYGKKKMMLISLVPFVLGSVICAVSADLIPMIIGRGFQGLGSGLIPLGIS
LMHDLLPREKAGSAIALMSSSMGIGGALGLPLAAAIAQFASWRVLFWFTALVALTVGAVIWKAIPARPRIVRSGGFDYFG
TLGLAMGIIALLLAVSKGSEWGWRSALTIGLFVAALVILVSWGWFETRQKSPLIDLRTTIRATVLMTNIASILIGFTMYG
MNLILPQVMQLPVILGYGLGRVEQVVWWALGLGESPACGIAGLAAVTVVLLSWLRDGDLADESQ
>Mature_384_residues
MMDSYSKAAMGSVLMALQFASYCIMHKICTIHIMSSSPPESATPQIKYGLLVVTLASAGITVSLAQTLVIPIIGRLPEIF
NTTAANASWIITVTLLVGAVATPVMGRLADMYGKKKMMLISLVPFVLGSVICAVSADLIPMIIGRGFQGLGSGLIPLGIS
LMHDLLPREKAGSAIALMSSSMGIGGALGLPLAAAIAQFASWRVLFWFTALVALTVGAVIWKAIPARPRIVRSGGFDYFG
TLGLAMGIIALLLAVSKGSEWGWRSALTIGLFVAALVILVSWGWFETRQKSPLIDLRTTIRATVLMTNIASILIGFTMYG
MNLILPQVMQLPVILGYGLGRVEQVVWWALGLGESPACGIAGLAAVTVVLLSWLRDGDLADESQ

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=255, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788710, Length=251, Percent_Identity=29.0836653386454, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324954, Length=251, Percent_Identity=24.7011952191235, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323735, Length=280, Percent_Identity=24.2857142857143, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322071, Length=174, Percent_Identity=25.8620689655172, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40650; Mature: 40650

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDSYSKAAMGSVLMALQFASYCIMHKICTIHIMSSSPPESATPQIKYGLLVVTLASAGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHEEHHHCCC
TVSLAQTLVIPIIGRLPEIFNTTAANASWIITVTLLVGAVATPVMGRLADMYGKKKMMLI
HHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SLVPFVLGSVICAVSADLIPMIIGRGFQGLGSGLIPLGISLMHDLLPREKAGSAIALMSS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCHHCCCEEEEHHC
SMGIGGALGLPLAAAIAQFASWRVLFWFTALVALTVGAVIWKAIPARPRIVRSGGFDYFG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHH
TLGLAMGIIALLLAVSKGSEWGWRSALTIGLFVAALVILVSWGWFETRQKSPLIDLRTTI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHH
RATVLMTNIASILIGFTMYGMNLILPQVMQLPVILGYGLGRVEQVVWWALGLGESPACGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCH
AGLAAVTVVLLSWLRDGDLADESQ
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMDSYSKAAMGSVLMALQFASYCIMHKICTIHIMSSSPPESATPQIKYGLLVVTLASAGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHEEHHHCCC
TVSLAQTLVIPIIGRLPEIFNTTAANASWIITVTLLVGAVATPVMGRLADMYGKKKMMLI
HHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SLVPFVLGSVICAVSADLIPMIIGRGFQGLGSGLIPLGISLMHDLLPREKAGSAIALMSS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCHHCCCEEEEHHC
SMGIGGALGLPLAAAIAQFASWRVLFWFTALVALTVGAVIWKAIPARPRIVRSGGFDYFG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHH
TLGLAMGIIALLLAVSKGSEWGWRSALTIGLFVAALVILVSWGWFETRQKSPLIDLRTTI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHH
RATVLMTNIASILIGFTMYGMNLILPQVMQLPVILGYGLGRVEQVVWWALGLGESPACGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCH
AGLAAVTVVLLSWLRDGDLADESQ
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]