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The map label for this gene is lldD2 [H]

Identifier: 145296919

GI number: 145296919

Start: 3131508

End: 3132770

Strand: Direct

Name: lldD2 [H]

Synonym: cgR_2819

Alternate gene names: 145296919

Gene position: 3131508-3132770 (Clockwise)

Preceding gene: 145296918

Following gene: 145296920

Centisome position: 94.49

GC content: 57.64

Gene sequence:

>1263_bases
ATGGTGAAACGTCAACTGCCCAACCCCGCAGAACTACTCGAACTCATGAAGTTCAAAAAGCCAGAGATCAACGGCAAGAA
ACGACGCCTAGACTCCGCGCTCACCATCTACGACCTGCGCAAAATTGCTAAACGACGCACCCCAGCCGCCGCATTCGACT
ACACCGACGGAGCAGCCGAGGCCGAACTGTCAATCAAACGCGCACGTGAAGCATTCGAAAACATCGAATTCCACCCAGAT
ATCCTCAAGCCTGCAGAGCACGTAGACACCACCACCCAAATCCTGGGCGGAACCTCCTCCATGCCTTTCGGCATCGCACC
AACCGGCTTCACCCGCCTCATGCAGACCGAAGGCGAAATCGCAGGTGCCGGAGCTGCAGGCGCCGCAGGTATTCCTTTCA
CCCTGTCCACCTTGGGCACCACCTCTATTGAAGACGTCAAGGCCACCAACCCCAACGGCCGAAACTGGTTCCAGCTTTAC
GTCATGCGTGACCGCGAAATCTCCTACGGACTCGTCGAACGCGCAGCCAAAGCGGGCTTCGACACCCTCATGTTCACCGT
GGACACCCCAATCGCTGGCTACCGTATCCGCGATTCCCGCAACGGATTCTCCATCCCACCACAGCTGACCCCATCCACCG
TGCTCAACGCAATTCCACGCCCATGGTGGTGGATCGACTTCCTCACCACGCCAACCTTGGAATTCGCATCCCTTTCCTCC
ACTGGAGGCACCGTAGGAGACCTCCTCAACTCCGCAATGGACCCCACCATTTCTTACGAAGACCTCAAGGTCATCCGTGA
AATGTGGCCAGGAAAACTCGTAGTCAAGGGCGTCCAAAACGTAGCAGACTCCGTCAAACTTCTCGACCAAGGCGTCGACG
GCCTCATTCTCTCCAACCACGGTGGCCGTCAGCTCGACCGCGCACCCGTCCCATTCCACCTCCTGCCACAGGTACGCAAG
GAAGTTGGATCTGAACCAACCATCATGATCGACACCGGCATCATGAACGGTGCCGACATCGTCGCAGCCGTAGCCATGGG
CGCCGATTTCACTCTCATCGGTCGTGCCTACCTCTACGGACTCATGGCCGGAGGCCGCGAAGGTGTCGATCGCACCATCG
CCATCCTGCGCAGCGAAATCAACCGCACCATGGCACTTCTCGGTGTTTCTTCCCTCGAAGAACTCGAACCACGCCACGTC
ACCCAACTGGCCAAGATGGTTCCAGTTTCTGACAACGTGAAGAACCTCAGCGACCTCGTCTAA

Upstream 100 bases:

>100_bases
GCATGTTGCCTCCTATCTGTGATCGCCTCGTTCTTCATCCAACGCGTCGCACACCAAGAGAACTAAAATCCAAGTAAAAC
CCCTCCGAAAGGAACCACCC

Downstream 100 bases:

>100_bases
TACCTGTTGCATCTGCTACTTGTGGCCAATTGAATTCTCTCCAATTGGCCACAAGTAGCATCACTATTTTAAAAGCCCCT
CGAAGAATCTACTTACAGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MVKRQLPNPAELLELMKFKKPEINGKKRRLDSALTIYDLRKIAKRRTPAAAFDYTDGAAEAELSIKRAREAFENIEFHPD
ILKPAEHVDTTTQILGGTSSMPFGIAPTGFTRLMQTEGEIAGAGAAGAAGIPFTLSTLGTTSIEDVKATNPNGRNWFQLY
VMRDREISYGLVERAAKAGFDTLMFTVDTPIAGYRIRDSRNGFSIPPQLTPSTVLNAIPRPWWWIDFLTTPTLEFASLSS
TGGTVGDLLNSAMDPTISYEDLKVIREMWPGKLVVKGVQNVADSVKLLDQGVDGLILSNHGGRQLDRAPVPFHLLPQVRK
EVGSEPTIMIDTGIMNGADIVAAVAMGADFTLIGRAYLYGLMAGGREGVDRTIAILRSEINRTMALLGVSSLEELEPRHV
TQLAKMVPVSDNVKNLSDLV

Sequences:

>Translated_420_residues
MVKRQLPNPAELLELMKFKKPEINGKKRRLDSALTIYDLRKIAKRRTPAAAFDYTDGAAEAELSIKRAREAFENIEFHPD
ILKPAEHVDTTTQILGGTSSMPFGIAPTGFTRLMQTEGEIAGAGAAGAAGIPFTLSTLGTTSIEDVKATNPNGRNWFQLY
VMRDREISYGLVERAAKAGFDTLMFTVDTPIAGYRIRDSRNGFSIPPQLTPSTVLNAIPRPWWWIDFLTTPTLEFASLSS
TGGTVGDLLNSAMDPTISYEDLKVIREMWPGKLVVKGVQNVADSVKLLDQGVDGLILSNHGGRQLDRAPVPFHLLPQVRK
EVGSEPTIMIDTGIMNGADIVAAVAMGADFTLIGRAYLYGLMAGGREGVDRTIAILRSEINRTMALLGVSSLEELEPRHV
TQLAKMVPVSDNVKNLSDLV
>Mature_420_residues
MVKRQLPNPAELLELMKFKKPEINGKKRRLDSALTIYDLRKIAKRRTPAAAFDYTDGAAEAELSIKRAREAFENIEFHPD
ILKPAEHVDTTTQILGGTSSMPFGIAPTGFTRLMQTEGEIAGAGAAGAAGIPFTLSTLGTTSIEDVKATNPNGRNWFQLY
VMRDREISYGLVERAAKAGFDTLMFTVDTPIAGYRIRDSRNGFSIPPQLTPSTVLNAIPRPWWWIDFLTTPTLEFASLSS
TGGTVGDLLNSAMDPTISYEDLKVIREMWPGKLVVKGVQNVADSVKLLDQGVDGLILSNHGGRQLDRAPVPFHLLPQVRK
EVGSEPTIMIDTGIMNGADIVAAVAMGADFTLIGRAYLYGLMAGGREGVDRTIAILRSEINRTMALLGVSSLEELEPRHV
TQLAKMVPVSDNVKNLSDLV

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=365, Percent_Identity=32.0547945205479, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI54234014, Length=375, Percent_Identity=30.6666666666667, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI7705393, Length=375, Percent_Identity=30.6666666666667, Blast_Score=192, Evalue=3e-49,
Organism=Escherichia coli, GI1790033, Length=381, Percent_Identity=36.745406824147, Blast_Score=231, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI193208036, Length=371, Percent_Identity=35.5795148247978, Blast_Score=224, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI32566217, Length=287, Percent_Identity=35.5400696864112, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323587, Length=378, Percent_Identity=30.4232804232804, Blast_Score=194, Evalue=3e-50,
Organism=Drosophila melanogaster, GI281363140, Length=376, Percent_Identity=35.9042553191489, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI78707190, Length=376, Percent_Identity=35.9042553191489, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI78707188, Length=376, Percent_Identity=35.9042553191489, Blast_Score=237, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 45809; Mature: 45809

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH ; PS00144 ASN_GLN_ASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKRQLPNPAELLELMKFKKPEINGKKRRLDSALTIYDLRKIAKRRTPAAAFDYTDGAAE
CCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCH
AELSIKRAREAFENIEFHPDILKPAEHVDTTTQILGGTSSMPFGIAPTGFTRLMQTEGEI
HHHHHHHHHHHHHCCCCCCCCCCCHHHHCHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCC
AGAGAAGAAGIPFTLSTLGTTSIEDVKATNPNGRNWFQLYVMRDREISYGLVERAAKAGF
CCCCCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCC
DTLMFTVDTPIAGYRIRDSRNGFSIPPQLTPSTVLNAIPRPWWWIDFLTTPTLEFASLSS
CEEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCHHHHCCCC
TGGTVGDLLNSAMDPTISYEDLKVIREMWPGKLVVKGVQNVADSVKLLDQGVDGLILSNH
CCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GGRQLDRAPVPFHLLPQVRKEVGSEPTIMIDTGIMNGADIVAAVAMGADFTLIGRAYLYG
CCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHH
LMAGGREGVDRTIAILRSEINRTMALLGVSSLEELEPRHVTQLAKMVPVSDNVKNLSDLV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHCC
>Mature Secondary Structure
MVKRQLPNPAELLELMKFKKPEINGKKRRLDSALTIYDLRKIAKRRTPAAAFDYTDGAAE
CCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCH
AELSIKRAREAFENIEFHPDILKPAEHVDTTTQILGGTSSMPFGIAPTGFTRLMQTEGEI
HHHHHHHHHHHHHCCCCCCCCCCCHHHHCHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCC
AGAGAAGAAGIPFTLSTLGTTSIEDVKATNPNGRNWFQLYVMRDREISYGLVERAAKAGF
CCCCCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCC
DTLMFTVDTPIAGYRIRDSRNGFSIPPQLTPSTVLNAIPRPWWWIDFLTTPTLEFASLSS
CEEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCHHHHCCCC
TGGTVGDLLNSAMDPTISYEDLKVIREMWPGKLVVKGVQNVADSVKLLDQGVDGLILSNH
CCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GGRQLDRAPVPFHLLPQVRKEVGSEPTIMIDTGIMNGADIVAAVAMGADFTLIGRAYLYG
CCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHH
LMAGGREGVDRTIAILRSEINRTMALLGVSSLEELEPRHVTQLAKMVPVSDNVKNLSDLV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]