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The map label for this gene is folB [H]

Identifier: 145296689

GI number: 145296689

Start: 2865396

End: 2865788

Strand: Reverse

Name: folB [H]

Synonym: cgR_2594

Alternate gene names: 145296689

Gene position: 2865788-2865396 (Counterclockwise)

Preceding gene: 145296690

Following gene: 145296688

Centisome position: 86.47

GC content: 52.93

Gene sequence:

>393_bases
ATGGCTGATCGTATTGAACTTAAAGGCCTTGAATGCTTCGGACACCACGGTGTGTTCGACTTTGAAAAAGAGCAAGGCCA
GCCCTTCATTGTGGATGTCACCTGCTGGATGGATTTCGATGCCGCAGGTGCCAGCGATGACCTTTCCGACACCGTAGATT
ACGGCGCGTTGGCATTGTTGGTTGCTGAAATCGTGGAAGGCCCATCCAGGGATTTGATCGAGACGGTGGCTACGGAATCT
GCGGATGCTGTGATGGCTAAATTTGATGCGCTTCATGCGGTGGAAGTAACCATCCATAAGCCCAAAGCACCGATCCCACG
TACTTTTGCTGACGTCGCGGTGGTTGCCCGACGTTCCAGGAAATCCATGGCTGCTGGAAGGAGCAACGCCTAA

Upstream 100 bases:

>100_bases
TCTGCACATATGGGAGCATGGGGTGTGCGCGTGCACGATGTCCCAGTATCAAGGGACGCTGTTGATGTTGCCGCATTGTG
GCGAAGTGGAGGAACTCACC

Downstream 100 bases:

>100_bases
TGCATGCAGTTTTGTCCATCGGTTCCAACATGGATGATCGCTACGCGCTGCTCAACACAGTGATCGAGGAATTCAAAGAT
GAGATCGTGGCGCAGTCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MADRIELKGLECFGHHGVFDFEKEQGQPFIVDVTCWMDFDAAGASDDLSDTVDYGALALLVAEIVEGPSRDLIETVATES
ADAVMAKFDALHAVEVTIHKPKAPIPRTFADVAVVARRSRKSMAAGRSNA

Sequences:

>Translated_130_residues
MADRIELKGLECFGHHGVFDFEKEQGQPFIVDVTCWMDFDAAGASDDLSDTVDYGALALLVAEIVEGPSRDLIETVATES
ADAVMAKFDALHAVEVTIHKPKAPIPRTFADVAVVARRSRKSMAAGRSNA
>Mature_129_residues
ADRIELKGLECFGHHGVFDFEKEQGQPFIVDVTCWMDFDAAGASDDLSDTVDYGALALLVAEIVEGPSRDLIETVATESA
DAVMAKFDALHAVEVTIHKPKAPIPRTFADVAVVARRSRKSMAAGRSNA

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14021; Mature: 13890

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRIELKGLECFGHHGVFDFEKEQGQPFIVDVTCWMDFDAAGASDDLSDTVDYGALALL
CCCCCCCCCEEEECCCCCCCCHHCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
VAEIVEGPSRDLIETVATESADAVMAKFDALHAVEVTIHKPKAPIPRTFADVAVVARRSR
HHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHH
KSMAAGRSNA
HHHCCCCCCC
>Mature Secondary Structure 
ADRIELKGLECFGHHGVFDFEKEQGQPFIVDVTCWMDFDAAGASDDLSDTVDYGALALL
CCCCCCCCEEEECCCCCCCCHHCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
VAEIVEGPSRDLIETVATESADAVMAKFDALHAVEVTIHKPKAPIPRTFADVAVVARRSR
HHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHH
KSMAAGRSNA
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]