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The map label for this gene is pcpB [H]

Identifier: 145296679

GI number: 145296679

Start: 2854341

End: 2856224

Strand: Direct

Name: pcpB [H]

Synonym: cgR_2584

Alternate gene names: 145296679

Gene position: 2854341-2856224 (Clockwise)

Preceding gene: 145296678

Following gene: 145296696

Centisome position: 86.13

GC content: 55.73

Gene sequence:

>1884_bases
ATGCAGTTTCATTATGATGGATACGCAACCGGTGACCCAATGGAGATGCGCGCGGAAGGTAGCGGAATCAACCGCCCGGA
CGATCTCCCCGAGGTCATGGATGTTCTCATCGTTGGTGCAGGTCCCGCTGGCACCATCGCAGCGGCTCAGCTTTCCCGAT
TCCCCAATGTGACCACCCGCCTCGTAGAGAGAAGCGACCGTCGCCTCGAACTAGCCAATGCAGATGGCGTGCACTCCCGA
ACCATTGAAACTTTCCAGGCATTTGGTTTCGCCCACGAGATCCTCGCCGAAGCTCATGAAATCACCGACATGGCGTTCTG
GAAGCCGGACCCGCAAAACCCTCGTGAGATCATTCGCGACAACAGCACCCGCGAGCTGCCACAGCACATCAGTGAATTTC
CGATGGCGTTGCTCACCCAGACCCGCATCATCGACCACTTCAACCGGTTCATGAAGAACTCCCCAACCAGGATGAAGCCT
GACTATGGATACGAGTTCGTGGACTTTGAAGTAGAAGAAGACGCAGAATATCCGGTAATTGTCACCCTCCGCCGCACCAG
TGGCGAGCAAACTGGCGAATTGGTCACCGTCCGCACCAAGTATCTGGTCGGTGCCGATGGTGCACGAAGCCAGGTGCGCA
AATCACTGGGATACCGACTCCAAGGTAAGCAGGCTAACCACGCTTGGGGTGTGATGGATATTCACGCGAACACCGAGTTC
CCCGACGTGCGCAAGAAGTGCACCATCAAATCTGATTCGGGTCGCACCATCTTGCTCATCCCACGTGAGGGTGGCTTCCT
CTTCCGTCTCTACGTTGACCTGGGCGAAGTACCTGATGATGGCAGCAAGGCTGTTCGTGATACCCCACTCCAGGATGTCA
TCGACACCGCGAACCAGATCATGGCTCCATTCACCCTCGACGTGAAAAACGTTGTGTGGAACTCCATCTACGAGGTAGGC
CACCGCGTCGCAGACCATTTCGATGACCGTGTTTCAGAAAAAACCTCGAGCGAACACCCACGCATTTTCATTGCTGGCGA
CGCCTGCCACACCCACAGCGCTAAGGCTGGCCAAGGCATGAACGTGTCCATGCAGGACGGATTCAACCTTGGCTGGAAGC
TTGGACATGTGGCCAGCGGAAATAGCCCACGCGAACTACTTCAGACCTACGCTGAAGAGCGCGAAGACATTGCCTACAAG
CTCATCGAGTACGACAAGAACTGGTCAACACTCATGGCAAAGCCAAGCAGCGAAATGGGCAGTGCCCAAGACCTTGAGGA
TTTCTACCGCGCGAACTCTGAGTTCAATGCCGGCTACATGACACACTACCCGCCTTCTTCCATCACGATGGATGGCAGCA
ACCAAGATCTGGCAAAGGGCTACCCAATTGGCCGACGCTTCAAGTCAGCAATGGTTGGTCGAGTCTGCGACTTCACCGAA
ACGCACCTCGGCCACCAAGCCACTGCCGACGGACGCATGCGCGCATACGTCTTTGCAGGATCCGATGCACTTAACGGCGA
GGGTTCTGAGCTAGACCGCTGGTCAGAGTGGGCCGAGGCGCACCTTGACCCCACGCTTGTCGACGCCAAGGTTATCTACC
AAAGCCCTTATACCGAGCTCGACACCCGCCAGGTTCCATCCGTGTTCAAACCTGCAGTCGGGATCTTCGAACTGACCAAT
GTGGAAAACTCCTTCGGTATCACCACGGACTCCGACATCTTTGATAGTCGCGAGATCTCCCGCGATGGTGTCGTGGTGGT
AGTCCGACCAGACCAATACGTTTCCGGAATCTTCCCACTCACTGATACCCAAGGGCTTGGCGAATTCCTCACCGGATACT
TCCCCAAAATGAAAGGCGCACATCAGCTAGTTAAGGCGAACTAG

Upstream 100 bases:

>100_bases
ATCACACTTTCATTCAGAGTGTGAGCTGAACTACATTTCTGGTTACTGTACGGAACACGCTCCGTGAATGAGATAGGAAA
TCCCCTCGAAAGGACCAGAC

Downstream 100 bases:

>100_bases
GGCGCAGCTGTTAAAACAGTGGACCTACTGCTCAAAATGAGCAGTAGGTCCACTGTTACCTAACCGAGTACAGGTCGAAG
AACTCGAAAAGTCTTAAGAT

Product: phenol 2-monooxygenase

Products: NA

Alternate protein names: Pentachlorophenol hydroxylase [H]

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MQFHYDGYATGDPMEMRAEGSGINRPDDLPEVMDVLIVGAGPAGTIAAAQLSRFPNVTTRLVERSDRRLELANADGVHSR
TIETFQAFGFAHEILAEAHEITDMAFWKPDPQNPREIIRDNSTRELPQHISEFPMALLTQTRIIDHFNRFMKNSPTRMKP
DYGYEFVDFEVEEDAEYPVIVTLRRTSGEQTGELVTVRTKYLVGADGARSQVRKSLGYRLQGKQANHAWGVMDIHANTEF
PDVRKKCTIKSDSGRTILLIPREGGFLFRLYVDLGEVPDDGSKAVRDTPLQDVIDTANQIMAPFTLDVKNVVWNSIYEVG
HRVADHFDDRVSEKTSSEHPRIFIAGDACHTHSAKAGQGMNVSMQDGFNLGWKLGHVASGNSPRELLQTYAEEREDIAYK
LIEYDKNWSTLMAKPSSEMGSAQDLEDFYRANSEFNAGYMTHYPPSSITMDGSNQDLAKGYPIGRRFKSAMVGRVCDFTE
THLGHQATADGRMRAYVFAGSDALNGEGSELDRWSEWAEAHLDPTLVDAKVIYQSPYTELDTRQVPSVFKPAVGIFELTN
VENSFGITTDSDIFDSREISRDGVVVVVRPDQYVSGIFPLTDTQGLGEFLTGYFPKMKGAHQLVKAN

Sequences:

>Translated_627_residues
MQFHYDGYATGDPMEMRAEGSGINRPDDLPEVMDVLIVGAGPAGTIAAAQLSRFPNVTTRLVERSDRRLELANADGVHSR
TIETFQAFGFAHEILAEAHEITDMAFWKPDPQNPREIIRDNSTRELPQHISEFPMALLTQTRIIDHFNRFMKNSPTRMKP
DYGYEFVDFEVEEDAEYPVIVTLRRTSGEQTGELVTVRTKYLVGADGARSQVRKSLGYRLQGKQANHAWGVMDIHANTEF
PDVRKKCTIKSDSGRTILLIPREGGFLFRLYVDLGEVPDDGSKAVRDTPLQDVIDTANQIMAPFTLDVKNVVWNSIYEVG
HRVADHFDDRVSEKTSSEHPRIFIAGDACHTHSAKAGQGMNVSMQDGFNLGWKLGHVASGNSPRELLQTYAEEREDIAYK
LIEYDKNWSTLMAKPSSEMGSAQDLEDFYRANSEFNAGYMTHYPPSSITMDGSNQDLAKGYPIGRRFKSAMVGRVCDFTE
THLGHQATADGRMRAYVFAGSDALNGEGSELDRWSEWAEAHLDPTLVDAKVIYQSPYTELDTRQVPSVFKPAVGIFELTN
VENSFGITTDSDIFDSREISRDGVVVVVRPDQYVSGIFPLTDTQGLGEFLTGYFPKMKGAHQLVKAN
>Mature_627_residues
MQFHYDGYATGDPMEMRAEGSGINRPDDLPEVMDVLIVGAGPAGTIAAAQLSRFPNVTTRLVERSDRRLELANADGVHSR
TIETFQAFGFAHEILAEAHEITDMAFWKPDPQNPREIIRDNSTRELPQHISEFPMALLTQTRIIDHFNRFMKNSPTRMKP
DYGYEFVDFEVEEDAEYPVIVTLRRTSGEQTGELVTVRTKYLVGADGARSQVRKSLGYRLQGKQANHAWGVMDIHANTEF
PDVRKKCTIKSDSGRTILLIPREGGFLFRLYVDLGEVPDDGSKAVRDTPLQDVIDTANQIMAPFTLDVKNVVWNSIYEVG
HRVADHFDDRVSEKTSSEHPRIFIAGDACHTHSAKAGQGMNVSMQDGFNLGWKLGHVASGNSPRELLQTYAEEREDIAYK
LIEYDKNWSTLMAKPSSEMGSAQDLEDFYRANSEFNAGYMTHYPPSSITMDGSNQDLAKGYPIGRRFKSAMVGRVCDFTE
THLGHQATADGRMRAYVFAGSDALNGEGSELDRWSEWAEAHLDPTLVDAKVIYQSPYTELDTRQVPSVFKPAVGIFELTN
VENSFGITTDSDIFDSREISRDGVVVVVRPDQYVSGIFPLTDTQGLGEFLTGYFPKMKGAHQLVKAN

Specific function: Dechlorination of pentachlorophenol to tetrachlorohydroquinone. Removes also hydrogen and nitro, amino, and cyano groups from benzene ring at the para position in relation to the hydroxyl of phenol [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=460, Percent_Identity=24.7826086956522, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: =1.14.13.50 [H]

Molecular weight: Translated: 70140; Mature: 70140

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFHYDGYATGDPMEMRAEGSGINRPDDLPEVMDVLIVGAGPAGTIAAAQLSRFPNVTTR
CCEECCCCCCCCCCEEEECCCCCCCCCCHHHHHHEEEECCCCCCHHHHHHHHHCCCHHHH
LVERSDRRLELANADGVHSRTIETFQAFGFAHEILAEAHEITDMAFWKPDPQNPREIIRD
HHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHCC
NSTRELPQHISEFPMALLTQTRIIDHFNRFMKNSPTRMKPDYGYEFVDFEVEEDAEYPVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEE
VTLRRTSGEQTGELVTVRTKYLVGADGARSQVRKSLGYRLQGKQANHAWGVMDIHANTEF
EEEECCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCEECCCCCCCCCEEEEEECCCCC
PDVRKKCTIKSDSGRTILLIPREGGFLFRLYVDLGEVPDDGSKAVRDTPLQDVIDTANQI
CCHHHHEEEECCCCCEEEEEECCCCEEEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHH
MAPFTLDVKNVVWNSIYEVGHRVADHFDDRVSEKTSSEHPRIFIAGDACHTHSAKAGQGM
HCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCC
NVSMQDGFNLGWKLGHVASGNSPRELLQTYAEEREDIAYKLIEYDKNWSTLMAKPSSEMG
EEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHCC
SAQDLEDFYRANSEFNAGYMTHYPPSSITMDGSNQDLAKGYPIGRRFKSAMVGRVCDFTE
CHHHHHHHHHCCCCCCCCCEEECCCCCEEECCCCCHHHCCCCHHHHHHHHHHHHHHCCHH
THLGHQATADGRMRAYVFAGSDALNGEGSELDRWSEWAEAHLDPTLVDAKVIYQSPYTEL
HHCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHCCEEEEECCCCCCC
DTRQVPSVFKPAVGIFELTNVENSFGITTDSDIFDSREISRDGVVVVVRPDQYVSGIFPL
CHHHCCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCC
TDTQGLGEFLTGYFPKMKGAHQLVKAN
CCCCHHHHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure
MQFHYDGYATGDPMEMRAEGSGINRPDDLPEVMDVLIVGAGPAGTIAAAQLSRFPNVTTR
CCEECCCCCCCCCCEEEECCCCCCCCCCHHHHHHEEEECCCCCCHHHHHHHHHCCCHHHH
LVERSDRRLELANADGVHSRTIETFQAFGFAHEILAEAHEITDMAFWKPDPQNPREIIRD
HHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHCC
NSTRELPQHISEFPMALLTQTRIIDHFNRFMKNSPTRMKPDYGYEFVDFEVEEDAEYPVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEE
VTLRRTSGEQTGELVTVRTKYLVGADGARSQVRKSLGYRLQGKQANHAWGVMDIHANTEF
EEEECCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCEECCCCCCCCCEEEEEECCCCC
PDVRKKCTIKSDSGRTILLIPREGGFLFRLYVDLGEVPDDGSKAVRDTPLQDVIDTANQI
CCHHHHEEEECCCCCEEEEEECCCCEEEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHH
MAPFTLDVKNVVWNSIYEVGHRVADHFDDRVSEKTSSEHPRIFIAGDACHTHSAKAGQGM
HCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCC
NVSMQDGFNLGWKLGHVASGNSPRELLQTYAEEREDIAYKLIEYDKNWSTLMAKPSSEMG
EEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHCC
SAQDLEDFYRANSEFNAGYMTHYPPSSITMDGSNQDLAKGYPIGRRFKSAMVGRVCDFTE
CHHHHHHHHHCCCCCCCCCEEECCCCCEEECCCCCHHHCCCCHHHHHHHHHHHHHHCCHH
THLGHQATADGRMRAYVFAGSDALNGEGSELDRWSEWAEAHLDPTLVDAKVIYQSPYTEL
HHCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHCCEEEEECCCCCCC
DTRQVPSVFKPAVGIFELTNVENSFGITTDSDIFDSREISRDGVVVVVRPDQYVSGIFPL
CHHHCCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCC
TDTQGLGEFLTGYFPKMKGAHQLVKAN
CCCCHHHHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7678243; 12169590 [H]