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The map label for this gene is feaR [H]

Identifier: 145296678

GI number: 145296678

Start: 2853175

End: 2854188

Strand: Direct

Name: feaR [H]

Synonym: cgR_2583

Alternate gene names: 145296678

Gene position: 2853175-2854188 (Clockwise)

Preceding gene: 145296676

Following gene: 145296679

Centisome position: 86.09

GC content: 52.66

Gene sequence:

>1014_bases
ATGACTGCTCAACCAGACCACGAGCTGCCAAGGCATCTCCGGTTCAGTACGAGCGGAATCCTCCCGGACAATCGCGTCCA
AATGTGGGAGGGCCACAATGCTCGCGCATTGCTTCCGCTCGACATTAGAACCATTGACGATCGCCCCATGCAGGCCTCAG
AAACCAACCTGCACCTCCCATCAATGCGGATGGCGAGCGTATTCGGGACTTCGCAATTTGTCGAGCGTTCAGAGAGTTTC
ATCTCAGAAAACCCCACGGGTGTGGTTGCAATATTCTTTGCGACTGAAGGTGAAGCAGTCTTCTTCCACCGTGGTGGACA
TGTAGCGCTTCGCCCAGGTCAGGCCATTGTTTACGACGCCGACCGGCCATTTCTCCGCGGATTCAACAATCGCTTCCGCG
AGCTAGTTCTCACCATCCCGAAGCAGCGCTACCTTGAAATTGTTGGCTCAAAAGGCCCTGAGCTTCCCGCTATTTTTGAG
TTCGGGGCAACAGGAACGGCCAACGAACAAGCTTTAGCGCGGCTAGTTCAAGAATCCCTGCACAGGATTGAGAGTGGCGA
GCCGAAACATATCGATTCCAGCGGCCTTTTAGGAAAACCGTGGAGCGATATCGAGCACGAGGCCCAGGGACTTATCCGCA
ATGTGCTTGGCGATGCCACAAGTAGCGAAGAAGGCTTAATTTCTGCAGCCCAGAGATTTATTGACATCAATATTTCCGAT
AGTGGCTTACAAGCATCACGAATCGCCGCAGCCGTCGGAATTAGCGAACGCCAACTAAGTCGAATCTTCTCAGAATCAGG
ACAAACTATCGGACGCTACGTCCTAAACACCCGACTGGATTTTGCAAAGGAAGCGCTATCGACACCGGAGCGAGACAAGG
TTTCGGTCAGTGAGATCGGAAAGCGCTTTGGGTTCGCTTCTCCAAGTCATTTCAGTCGCACCTTCCGTGAGCGGTTTGAA
ATGACACCGCTTCAATGGAGGAAGGAATCGCAGCGTCAAACCTTTCAAGATTGA

Upstream 100 bases:

>100_bases
TTCTAACCCATGTGCATGTCACCAGCACGGATGTAATCCGCTTTTATCGACTTACATATTAGTGACTTATGTGATCTGAG
ACTCTATTGTGGTACGCACC

Downstream 100 bases:

>100_bases
GGTTTTTGTTCTCGGGCGGACATCATCTTGCCCGAGACAGACAATAAGATAAATCACACTTTCATTCAGAGTGTGAGCTG
AACTACATTTCTGGTTACTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTAQPDHELPRHLRFSTSGILPDNRVQMWEGHNARALLPLDIRTIDDRPMQASETNLHLPSMRMASVFGTSQFVERSESF
ISENPTGVVAIFFATEGEAVFFHRGGHVALRPGQAIVYDADRPFLRGFNNRFRELVLTIPKQRYLEIVGSKGPELPAIFE
FGATGTANEQALARLVQESLHRIESGEPKHIDSSGLLGKPWSDIEHEAQGLIRNVLGDATSSEEGLISAAQRFIDINISD
SGLQASRIAAAVGISERQLSRIFSESGQTIGRYVLNTRLDFAKEALSTPERDKVSVSEIGKRFGFASPSHFSRTFRERFE
MTPLQWRKESQRQTFQD

Sequences:

>Translated_337_residues
MTAQPDHELPRHLRFSTSGILPDNRVQMWEGHNARALLPLDIRTIDDRPMQASETNLHLPSMRMASVFGTSQFVERSESF
ISENPTGVVAIFFATEGEAVFFHRGGHVALRPGQAIVYDADRPFLRGFNNRFRELVLTIPKQRYLEIVGSKGPELPAIFE
FGATGTANEQALARLVQESLHRIESGEPKHIDSSGLLGKPWSDIEHEAQGLIRNVLGDATSSEEGLISAAQRFIDINISD
SGLQASRIAAAVGISERQLSRIFSESGQTIGRYVLNTRLDFAKEALSTPERDKVSVSEIGKRFGFASPSHFSRTFRERFE
MTPLQWRKESQRQTFQD
>Mature_336_residues
TAQPDHELPRHLRFSTSGILPDNRVQMWEGHNARALLPLDIRTIDDRPMQASETNLHLPSMRMASVFGTSQFVERSESFI
SENPTGVVAIFFATEGEAVFFHRGGHVALRPGQAIVYDADRPFLRGFNNRFRELVLTIPKQRYLEIVGSKGPELPAIFEF
GATGTANEQALARLVQESLHRIESGEPKHIDSSGLLGKPWSDIEHEAQGLIRNVLGDATSSEEGLISAAQRFIDINISDS
GLQASRIAAAVGISERQLSRIFSESGQTIGRYVLNTRLDFAKEALSTPERDKVSVSEIGKRFGFASPSHFSRTFRERFEM
TPLQWRKESQRQTFQD

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=323, Percent_Identity=23.5294117647059, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37737; Mature: 37606

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS01124 HTH_ARAC_FAMILY_2 ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQPDHELPRHLRFSTSGILPDNRVQMWEGHNARALLPLDIRTIDDRPMQASETNLHLP
CCCCCCCHHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCC
SMRMASVFGTSQFVERSESFISENPTGVVAIFFATEGEAVFFHRGGHVALRPGQAIVYDA
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCEEEECCCCEEEEEC
DRPFLRGFNNRFRELVLTIPKQRYLEIVGSKGPELPAIFEFGATGTANEQALARLVQESL
CCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHH
HRIESGEPKHIDSSGLLGKPWSDIEHEAQGLIRNVLGDATSSEEGLISAAQRFIDINISD
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCC
SGLQASRIAAAVGISERQLSRIFSESGQTIGRYVLNTRLDFAKEALSTPERDKVSVSEIG
CCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KRFGFASPSHFSRTFRERFEMTPLQWRKESQRQTFQD
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAQPDHELPRHLRFSTSGILPDNRVQMWEGHNARALLPLDIRTIDDRPMQASETNLHLP
CCCCCCHHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCC
SMRMASVFGTSQFVERSESFISENPTGVVAIFFATEGEAVFFHRGGHVALRPGQAIVYDA
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCEEEECCCCEEEEEC
DRPFLRGFNNRFRELVLTIPKQRYLEIVGSKGPELPAIFEFGATGTANEQALARLVQESL
CCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHH
HRIESGEPKHIDSSGLLGKPWSDIEHEAQGLIRNVLGDATSSEEGLISAAQRFIDINISD
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCC
SGLQASRIAAAVGISERQLSRIFSESGQTIGRYVLNTRLDFAKEALSTPERDKVSVSEIG
CCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KRFGFASPSHFSRTFRERFEMTPLQWRKESQRQTFQD
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]