Click here to switch to the map view.

The map label for this gene is yjmD [H]

Identifier: 145296613

GI number: 145296613

Start: 2787176

End: 2788267

Strand: Reverse

Name: yjmD [H]

Synonym: cgR_2521

Alternate gene names: 145296613

Gene position: 2788267-2787176 (Counterclockwise)

Preceding gene: 145296614

Following gene: 145296612

Centisome position: 84.13

GC content: 52.56

Gene sequence:

>1092_bases
GTGACTGTCGCAGAATTCACCGAAATCAATACAAACGCAAAGACCATCACGGCTGCTGTTACTACTTCGAAGCAGACCAT
CGAGTTTCAGAATCTTCTAGCGCCGGCGATTGTGCCTGGTTCTGCACGGATCTCCATGGCAGCGGTCACACTGTGTGGCA
CTGACGCCCATATTTGGGATGATGATTACGCTTCAGAACTCCCTATTATTCAGGGACACGAAGCAGCAGGCATTATCACT
GAGATGGATCCTTCCGATGAAGGCAATGGATTCAATGTTGGCGATCGAGTTGTAATTTGCCCCATGTTCTACTGCGGCAA
GTGCTACGCATGTTCGGTTGGTCGTGTGAATGCTTGTAAGGAAATGAGCGTTTACGGCTGCTACGAAGATGGTTCTTTGG
TTGATGAACAGGTTGTTCCTTACGCGAACCTGTTTAAGATTCCAGATTCCCTTCCACTTGATTTGGCACCGATCGTAGAG
CCAATCTCGATTGCGATGCAGGCCTGCAAGCGTGGCCGTCCAGTGAGTGGCGAGAAGGTTATCGTCAACGGTGCTGGTCC
GATTGGTGTGCTGGCGGTTCGTTATCTGAAGGATCAGGGCTGCGAAGTCGCTGTGACCGATATGGTGCAGTCCCGCTTGG
ATCTGGCTAAGCACTGCGGTGCGGACAAGACTTTCGTGGTTGATGGCGGTTTCCCGAACGCTGTGCAGGCAGTGGAAGTT
GACACCTGGACTGACGGAAACGGCCCATCCCTGATCATCGATGCAACCGGCGTCCCAGCATCCCTAGCCGCTGCGATTGA
TCTCGTAGCAACCGCAGGACGCGTGGTGTGCGTGGGTATCTCTGACCGCGATCTGGTCTTTGATATGCGCAAGCTGGTAT
CCAAGGAGATCGATCTTTTGGGTTCCCGCAACTCCCAGAACCTGTTCCCAGAGTGCATTGCGCTGCTGGATAAGCACCAG
GACACCCTGCGCGCATTGGTTACCCACCGTTTTGATTTTGACAATCTCGATGAGGCGTTCACTACTTTGACCACACCAAA
CGCTGGTGTGGGAAAGATCGCCATTGATTTCCCAGGAGCTCAAAATGTCTAA

Upstream 100 bases:

>100_bases
ATCATGGATCAGGACCCTATCTACTCTGGTGGTTTCGTTTCAGAGCGTTTGGTTCGCCTGTGGAACGTTGCTTTCGGTGC
TATTGCGGAGAAGAACTAAC

Downstream 100 bases:

>100_bases
GCCACTTCTTTCCTCAGTTGCCGATTGGCCTGAAGAATTAGATGTCCTCGTGCTTGGGTCTGGTTGTGCTGGAATGACCG
CCGCACTTGTCGCGGCGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTVAEFTEINTNAKTITAAVTTSKQTIEFQNLLAPAIVPGSARISMAAVTLCGTDAHIWDDDYASELPIIQGHEAAGIIT
EMDPSDEGNGFNVGDRVVICPMFYCGKCYACSVGRVNACKEMSVYGCYEDGSLVDEQVVPYANLFKIPDSLPLDLAPIVE
PISIAMQACKRGRPVSGEKVIVNGAGPIGVLAVRYLKDQGCEVAVTDMVQSRLDLAKHCGADKTFVVDGGFPNAVQAVEV
DTWTDGNGPSLIIDATGVPASLAAAIDLVATAGRVVCVGISDRDLVFDMRKLVSKEIDLLGSRNSQNLFPECIALLDKHQ
DTLRALVTHRFDFDNLDEAFTTLTTPNAGVGKIAIDFPGAQNV

Sequences:

>Translated_363_residues
MTVAEFTEINTNAKTITAAVTTSKQTIEFQNLLAPAIVPGSARISMAAVTLCGTDAHIWDDDYASELPIIQGHEAAGIIT
EMDPSDEGNGFNVGDRVVICPMFYCGKCYACSVGRVNACKEMSVYGCYEDGSLVDEQVVPYANLFKIPDSLPLDLAPIVE
PISIAMQACKRGRPVSGEKVIVNGAGPIGVLAVRYLKDQGCEVAVTDMVQSRLDLAKHCGADKTFVVDGGFPNAVQAVEV
DTWTDGNGPSLIIDATGVPASLAAAIDLVATAGRVVCVGISDRDLVFDMRKLVSKEIDLLGSRNSQNLFPECIALLDKHQ
DTLRALVTHRFDFDNLDEAFTTLTTPNAGVGKIAIDFPGAQNV
>Mature_362_residues
TVAEFTEINTNAKTITAAVTTSKQTIEFQNLLAPAIVPGSARISMAAVTLCGTDAHIWDDDYASELPIIQGHEAAGIITE
MDPSDEGNGFNVGDRVVICPMFYCGKCYACSVGRVNACKEMSVYGCYEDGSLVDEQVVPYANLFKIPDSLPLDLAPIVEP
ISIAMQACKRGRPVSGEKVIVNGAGPIGVLAVRYLKDQGCEVAVTDMVQSRLDLAKHCGADKTFVVDGGFPNAVQAVEVD
TWTDGNGPSLIIDATGVPASLAAAIDLVATAGRVVCVGISDRDLVFDMRKLVSKEIDLLGSRNSQNLFPECIALLDKHQD
TLRALVTHRFDFDNLDEAFTTLTTPNAGVGKIAIDFPGAQNV

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=325, Percent_Identity=30.4615384615385, Blast_Score=145, Evalue=8e-35,
Organism=Escherichia coli, GI1787863, Length=342, Percent_Identity=33.0409356725146, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1790045, Length=334, Percent_Identity=29.3413173652695, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI226510992, Length=336, Percent_Identity=30.0595238095238, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1788407, Length=326, Percent_Identity=27.3006134969325, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788073, Length=307, Percent_Identity=26.3843648208469, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790718, Length=332, Percent_Identity=25, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI87082125, Length=369, Percent_Identity=26.0162601626016, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788075, Length=332, Percent_Identity=26.2048192771084, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081918, Length=291, Percent_Identity=26.8041237113402, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562876, Length=345, Percent_Identity=31.304347826087, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17562878, Length=330, Percent_Identity=32.1212121212121, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71988145, Length=282, Percent_Identity=24.113475177305, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323099, Length=340, Percent_Identity=27.0588235294118, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322619, Length=311, Percent_Identity=27.3311897106109, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319955, Length=311, Percent_Identity=27.0096463022508, Blast_Score=109, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6319257, Length=374, Percent_Identity=27.0053475935829, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319258, Length=208, Percent_Identity=27.8846153846154, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=286, Percent_Identity=26.2237762237762, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=282, Percent_Identity=25.177304964539, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=286, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323961, Length=286, Percent_Identity=25.8741258741259, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17737897, Length=343, Percent_Identity=30.6122448979592, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI17137530, Length=349, Percent_Identity=30.6590257879656, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI45550770, Length=319, Percent_Identity=23.5109717868339, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45551930, Length=319, Percent_Identity=23.5109717868339, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221457811, Length=319, Percent_Identity=23.5109717868339, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 38632; Mature: 38501

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAEFTEINTNAKTITAAVTTSKQTIEFQNLLAPAIVPGSARISMAAVTLCGTDAHIWD
CCCCCEEECCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEECC
DDYASELPIIQGHEAAGIITEMDPSDEGNGFNVGDRVVICPMFYCGKCYACSVGRVNACK
CCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCCEEEEECHHHCCCEEEECCCCCCCCC
EMSVYGCYEDGSLVDEQVVPYANLFKIPDSLPLDLAPIVEPISIAMQACKRGRPVSGEKV
CCEEEEECCCCCCCHHHHCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
IVNGAGPIGVLAVRYLKDQGCEVAVTDMVQSRLDLAKHCGADKTFVVDGGFPNAVQAVEV
EEECCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEE
DTWTDGNGPSLIIDATGVPASLAAAIDLVATAGRVVCVGISDRDLVFDMRKLVSKEIDLL
EECCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
GSRNSQNLFPECIALLDKHQDTLRALVTHRFDFDNLDEAFTTLTTPNAGVGKIAIDFPGA
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHEECCCCCCCCEEEEECCCC
QNV
CCC
>Mature Secondary Structure 
TVAEFTEINTNAKTITAAVTTSKQTIEFQNLLAPAIVPGSARISMAAVTLCGTDAHIWD
CCCCEEECCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEECC
DDYASELPIIQGHEAAGIITEMDPSDEGNGFNVGDRVVICPMFYCGKCYACSVGRVNACK
CCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCCEEEEECHHHCCCEEEECCCCCCCCC
EMSVYGCYEDGSLVDEQVVPYANLFKIPDSLPLDLAPIVEPISIAMQACKRGRPVSGEKV
CCEEEEECCCCCCCHHHHCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
IVNGAGPIGVLAVRYLKDQGCEVAVTDMVQSRLDLAKHCGADKTFVVDGGFPNAVQAVEV
EEECCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEE
DTWTDGNGPSLIIDATGVPASLAAAIDLVATAGRVVCVGISDRDLVFDMRKLVSKEIDLL
EECCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
GSRNSQNLFPECIALLDKHQDTLRALVTHRFDFDNLDEAFTTLTTPNAGVGKIAIDFPGA
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHEECCCCCCCCEEEEECCCC
QNV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]