Click here to switch to the map view.

The map label for this gene is ksdD [H]

Identifier: 145296611

GI number: 145296611

Start: 2783700

End: 2785478

Strand: Reverse

Name: ksdD [H]

Synonym: cgR_2519

Alternate gene names: 145296611

Gene position: 2785478-2783700 (Counterclockwise)

Preceding gene: 145296612

Following gene: 145296610

Centisome position: 84.05

GC content: 56.1

Gene sequence:

>1779_bases
ATGGTGGATAAAGCTTCCGAAGCGAAGTGGGACAAAGAAGTTGACCTGCTTGTTCTAGGATCAGGCGCAGCCGGACTCTC
TGCAGCACTCACCGGTGTTGTCGAAGGCCTAAACGTCCTGCTTCTGGAAAAGAGCGACTATATCGGTGGCACCACCGCAT
ATTCCGCTGGAACCATCTGGATCCCCAACAACCACTTCCAGCGCGAAGATGGCATCACCGATGACCGTGAAAAGGTAGAG
CGTTACCTAGACACCCTGGTTGGGGACAAATCGAATAAAGAAATGCGCATGGCGTATGTGGACCAAGGCCCGCACATGCT
GAAGTACATGGAAAACATCGGCGTGGAATTCCTCCGCTCACCAAACGTGGTGGACTACCACTCCGAACTTCCAGAAACCG
GCAAAACCGGCCGTGCACTTGAGCCAAAGCCTTTCGACGGCCGCGAGCTCGGCAAGGTCAACTTCGCGCACGTTAGGCCA
CCGGTCCACGAGTTCGCACTGATGAACGGCACCATGATGCTGCGCCGTCCAGAAGTCAATGTTCTTCTCGGACTCTTCTC
CAAACGTCCAAAACAAACTGTCGCCGCAGTGGGAACTGCACTCAAACTCGGTCTGCGCTGGGCAACCGACATGGTGAAAT
ACCCTCGTGGCACCCGCCTTGTCATGGGTAATGCACTGACTGCTCGGATGTACCACCAGGTGCTCACCCGTGGCGGCGAC
GTATGGCGAAACGCGCTGACCACTGAACTTATTAAAGAAGGTAATGCTGTTGTTGGAGCGGTAGTCAACCATGGGGGAGT
ATCCCACCGCATCCGTGTAAACAAGGGCGTGGTGCTGGCCGCAGGTGGATTCTCCCAGAATCCAGAACTGCGCAAGAAGT
ACATGCCAGAACCCACCCCACAGTTCTCCCGCACCAACGAAAGCGCCACCGGTGACACCATGGCCCTTGCTGCGAAAGCG
GGAGCACGCCTAGGCGACGACAACGGTGAAAACGCACTCTGGTTCCCATCATCGATCGGCACCCGCGCCGACGGATCCAC
CGCGGTGTACCCACACATTTGGGACCGTGGCCGCCCCGGAGTCATCGCAGTCAACGCAGCAGGCGAGCGCTTCGTCGATG
AATCTGTCTCCTACCACCGCTTCGTGCGCGCCATGTACGAATCCAACAAAACCACCCCGACTGTTCCAGCCTGGCTCATT
GTTGATTCCCACACCCTGGCAAAATACGGCCTCGGCATGATCACCATGCCTCACCTGCCTAAACTGGCTCTGCAAAAATA
CATCGACTCCGGATACCTGCACGCAGGATCATCCTTAGGCGAACTAGCTCGCAACATCGGTGTGGATGCACGCGGCCTGG
AACAAACCGTCAAACGCTACAACACCTTCGCCAAAACGGGTATCGACGAAGACTTCCATAAGGGCGAACTCCTCTTCGGT
CAAGCCGCCGGCGATCCAGACAACAAGCCAAACCCCAACGTTGGACCAATCAAGAAGGGGCCGTTCTACGCCATCGCTGT
AGTCCCAACCCCTTTGGCCACCGCTTTTGGCATCAGCATCAACCCCAACGGACAGGTCGTTAGTGAAGATGGAGAGCCAA
TCACTGGACTGTATTCCGCAGGAAATGATGCCCAATCTGTCATGGCTTCTGAATATCCTGGTGCTGGTTCACAGGTTGGT
TCCGGAATGACCTTTGGTTGGATCGCAGCACAGCACGCGGTGGGGAAAGTGGGAAAATCCGGAGGAGCTAAGGCAGGATA
TGCCGCGTCTTCTAAGTAA

Upstream 100 bases:

>100_bases
GCAGTGGGTAAGCACATCAGCCAATCCTTTCAGATGGAAACCACTGAAGCACTGAGCTTGACTCACTAAGAAACAAAAGT
AGAAGGAACAGAGAAGAACA

Downstream 100 bases:

>100_bases
TTGCTTGGTGGGTTGCTTACTAGTCCGATGATCGTGAGGGAAACCAGCAGAGCAGCACACAGTACAGAAGCTGACTTAAA
CCTTATTTGTAGTTGTCAAT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-keto-Delta(4)-steroid Delta(1)-dehydrogenase; KSDD; 3-oxo-Delta(4)-steroid 1-dehydrogenase; KSTD [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MVDKASEAKWDKEVDLLVLGSGAAGLSAALTGVVEGLNVLLLEKSDYIGGTTAYSAGTIWIPNNHFQREDGITDDREKVE
RYLDTLVGDKSNKEMRMAYVDQGPHMLKYMENIGVEFLRSPNVVDYHSELPETGKTGRALEPKPFDGRELGKVNFAHVRP
PVHEFALMNGTMMLRRPEVNVLLGLFSKRPKQTVAAVGTALKLGLRWATDMVKYPRGTRLVMGNALTARMYHQVLTRGGD
VWRNALTTELIKEGNAVVGAVVNHGGVSHRIRVNKGVVLAAGGFSQNPELRKKYMPEPTPQFSRTNESATGDTMALAAKA
GARLGDDNGENALWFPSSIGTRADGSTAVYPHIWDRGRPGVIAVNAAGERFVDESVSYHRFVRAMYESNKTTPTVPAWLI
VDSHTLAKYGLGMITMPHLPKLALQKYIDSGYLHAGSSLGELARNIGVDARGLEQTVKRYNTFAKTGIDEDFHKGELLFG
QAAGDPDNKPNPNVGPIKKGPFYAIAVVPTPLATAFGISINPNGQVVSEDGEPITGLYSAGNDAQSVMASEYPGAGSQVG
SGMTFGWIAAQHAVGKVGKSGGAKAGYAASSK

Sequences:

>Translated_592_residues
MVDKASEAKWDKEVDLLVLGSGAAGLSAALTGVVEGLNVLLLEKSDYIGGTTAYSAGTIWIPNNHFQREDGITDDREKVE
RYLDTLVGDKSNKEMRMAYVDQGPHMLKYMENIGVEFLRSPNVVDYHSELPETGKTGRALEPKPFDGRELGKVNFAHVRP
PVHEFALMNGTMMLRRPEVNVLLGLFSKRPKQTVAAVGTALKLGLRWATDMVKYPRGTRLVMGNALTARMYHQVLTRGGD
VWRNALTTELIKEGNAVVGAVVNHGGVSHRIRVNKGVVLAAGGFSQNPELRKKYMPEPTPQFSRTNESATGDTMALAAKA
GARLGDDNGENALWFPSSIGTRADGSTAVYPHIWDRGRPGVIAVNAAGERFVDESVSYHRFVRAMYESNKTTPTVPAWLI
VDSHTLAKYGLGMITMPHLPKLALQKYIDSGYLHAGSSLGELARNIGVDARGLEQTVKRYNTFAKTGIDEDFHKGELLFG
QAAGDPDNKPNPNVGPIKKGPFYAIAVVPTPLATAFGISINPNGQVVSEDGEPITGLYSAGNDAQSVMASEYPGAGSQVG
SGMTFGWIAAQHAVGKVGKSGGAKAGYAASSK
>Mature_592_residues
MVDKASEAKWDKEVDLLVLGSGAAGLSAALTGVVEGLNVLLLEKSDYIGGTTAYSAGTIWIPNNHFQREDGITDDREKVE
RYLDTLVGDKSNKEMRMAYVDQGPHMLKYMENIGVEFLRSPNVVDYHSELPETGKTGRALEPKPFDGRELGKVNFAHVRP
PVHEFALMNGTMMLRRPEVNVLLGLFSKRPKQTVAAVGTALKLGLRWATDMVKYPRGTRLVMGNALTARMYHQVLTRGGD
VWRNALTTELIKEGNAVVGAVVNHGGVSHRIRVNKGVVLAAGGFSQNPELRKKYMPEPTPQFSRTNESATGDTMALAAKA
GARLGDDNGENALWFPSSIGTRADGSTAVYPHIWDRGRPGVIAVNAAGERFVDESVSYHRFVRAMYESNKTTPTVPAWLI
VDSHTLAKYGLGMITMPHLPKLALQKYIDSGYLHAGSSLGELARNIGVDARGLEQTVKRYNTFAKTGIDEDFHKGELLFG
QAAGDPDNKPNPNVGPIKKGPFYAIAVVPTPLATAFGISINPNGQVVSEDGEPITGLYSAGNDAQSVMASEYPGAGSQVG
SGMTFGWIAAQHAVGKVGKSGGAKAGYAASSK

Specific function: Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3- ketosteroids. Is also involved in the formation of 1,4- androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.3.99.4 [H]

Molecular weight: Translated: 63651; Mature: 63651

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDKASEAKWDKEVDLLVLGSGAAGLSAALTGVVEGLNVLLLEKSDYIGGTTAYSAGTIW
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCEEE
IPNNHFQREDGITDDREKVERYLDTLVGDKSNKEMRMAYVDQGPHMLKYMENIGVEFLRS
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCHHHHCC
PNVVDYHSELPETGKTGRALEPKPFDGRELGKVNFAHVRPPVHEFALMNGTMMLRRPEVN
CCEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCEEEEECCCHH
VLLGLFSKRPKQTVAAVGTALKLGLRWATDMVKYPRGTRLVMGNALTARMYHQVLTRGGD
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCHH
VWRNALTTELIKEGNAVVGAVVNHGGVSHRIRVNKGVVLAAGGFSQNPELRKKYMPEPTP
HHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCHHHHHHCCCCCCC
QFSRTNESATGDTMALAAKAGARLGDDNGENALWFPSSIGTRADGSTAVYPHIWDRGRPG
CCCCCCCCCCCCCEEHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCCC
VIAVNAAGERFVDESVSYHRFVRAMYESNKTTPTVPAWLIVDSHTLAKYGLGMITMPHLP
EEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHCCCEEECCCCH
KLALQKYIDSGYLHAGSSLGELARNIGVDARGLEQTVKRYNTFAKTGIDEDFHKGELLFG
HHHHHHHHCCCCEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
QAAGDPDNKPNPNVGPIKKGPFYAIAVVPTPLATAFGISINPNGQVVSEDGEPITGLYSA
ECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHEEEEECCCCCEECCCCCCEEEEECC
GNDAQSVMASEYPGAGSQVGSGMTFGWIAAQHAVGKVGKSGGAKAGYAASSK
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVDKASEAKWDKEVDLLVLGSGAAGLSAALTGVVEGLNVLLLEKSDYIGGTTAYSAGTIW
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCEEE
IPNNHFQREDGITDDREKVERYLDTLVGDKSNKEMRMAYVDQGPHMLKYMENIGVEFLRS
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCHHHHCC
PNVVDYHSELPETGKTGRALEPKPFDGRELGKVNFAHVRPPVHEFALMNGTMMLRRPEVN
CCEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCEEEEECCCHH
VLLGLFSKRPKQTVAAVGTALKLGLRWATDMVKYPRGTRLVMGNALTARMYHQVLTRGGD
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCHH
VWRNALTTELIKEGNAVVGAVVNHGGVSHRIRVNKGVVLAAGGFSQNPELRKKYMPEPTP
HHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCHHHHHHCCCCCCC
QFSRTNESATGDTMALAAKAGARLGDDNGENALWFPSSIGTRADGSTAVYPHIWDRGRPG
CCCCCCCCCCCCCEEHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCCC
VIAVNAAGERFVDESVSYHRFVRAMYESNKTTPTVPAWLIVDSHTLAKYGLGMITMPHLP
EEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHCCCEEECCCCH
KLALQKYIDSGYLHAGSSLGELARNIGVDARGLEQTVKRYNTFAKTGIDEDFHKGELLFG
HHHHHHHHCCCCEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
QAAGDPDNKPNPNVGPIKKGPFYAIAVVPTPLATAFGISINPNGQVVSEDGEPITGLYSA
ECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHEEEEECCCCCEECCCCCCEEEEECC
GNDAQSVMASEYPGAGSQVGSGMTFGWIAAQHAVGKVGKSGGAKAGYAASSK
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA