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The map label for this gene is ptrB [H]

Identifier: 145296590

GI number: 145296590

Start: 2758541

End: 2760661

Strand: Reverse

Name: ptrB [H]

Synonym: cgR_2498

Alternate gene names: 145296590

Gene position: 2760661-2758541 (Counterclockwise)

Preceding gene: 145296591

Following gene: 145296589

Centisome position: 83.3

GC content: 55.3

Gene sequence:

>2121_bases
ATGTCTGAACGCCTAAACGCTCCGCAAGCACCAATCCATCCCATCACCCGAACCCACCACGGTATTGATTTCGTAGACAA
CTATGAATGGCTGAGGGATAAAGAATCCCAAGAAACCTTAGACTATCTGGAGGCGGAGAATGCGTTCACCAAGCAGGAGA
CTGAACAGCTAGCCACACTGCGGGACAACATCTACGAAGAGATTAAGTCACGCGTTAAAGAAACCGACATGTCTATCCCA
GTGCGTGCCGGAAAGTACTGGTATTACTCTCGCACTGAAGAAGGCAAGAGCTACGGCTATTCCTGCCGCATTCCAGTGAC
TGAAGGGTCGGATGCATGGACCCCTCCTGTTATCCCTGAGGGTGAGCCAGCGCAGGGTGAAACCATCATCATGGATGCCA
ACGAGTTGGCAGAAGGCCACGAATTCTTCTCCATGGGTGCATCATCTGTCACCACCTCTGGCCGCTACCTTGCGTATTCC
ACCGATGTCACGGGTGAAGAGCGCTTCACGTTGCGCATCAAGGATCTAGAAACTGGCGAGCTGCTTCCTGATACCCTGAC
CGGAATTTTCTACGGCGCTACTTGGGTGGGGGAGGAGTACCTCTTTTACCAGCGCGTCGATGATGCGTGGCGTCCAGATA
CTGTGTGGCGTCACAAGGTGGGCACCCCGGTCGAAGAAGACGTGTTGGTGTACCACGAGCCTGATGAACGTTATTCCACC
TGGGTGGGCACCACTCGTTCAGAAAAGTTCATCCTTTTTGGTTGCGCCTCCAAGATCACCTCTGAAGTCCGCGTGCTTCC
TTTCGACCAGCCAGAGGGCACCCCTGAGGTGCTGATTCCGCGCGCGGAGGGTGTGGAATACGACGTCGATCATGCAGTCG
TAGACGGCTCCGATATTTGGTTGGTCACACACAACGCCGAGGGCCCGAACTTTTCGGTGGGGTGGGCTGGCGTCGACAAG
CTCAATTCTTTGGACGCGCTGACGCCACTCGTCGCGCACAAGGATGACGTGCGCATTGAGGGCGTCGATACCTACCGCGA
TTTCATCATCCTGGGCTACAGGTCCGGCGCGATCGGCCAGGTCGCGATCATGAAGCTTATCGACGGCACCTTCGGCGAAT
TCCAACAGCTGGAATTCGACGAGGAAATCTACACCGTGGCATCGGGCGGAAACCCAGAATGGGACGCCCCCGTCATTCGC
CTGTCCTACGGATCGTTCACCACTCCAGCGCAGCTGTTTAACTACTGGATTGAATCCGGCGAACGCACACTGCTGAAGCA
GCAGGAAGTGCTCGGCGGATACAACCCGTCAGACTATGTGGCCTCCCGATTGTGGGTCACTGCGAAAGATGGCGCGCAGA
TTCCAGTGTCCTTGGTGCACCGCACTGACCTGGATGTATCCAAGCCCAACCCCGCGTTGCTCTACGGCTATGGTTCCTAC
GAATCATCCATTGATCCAGGCTTCTCTATCGCGCGTTTGTCACTGATGGATCGTGGCATGATTTTTGCGATTGCCCACGT
TCGTGGCGGTGGCGAAATGGGTCGTGGCTGGTACGACAACGGCAAAACCACCACGAAGAAAAACACCTTCACCGACTTCA
TTGATGTTGCCGACGCCCTCATCGAGCAGAAGATTTCTGCCCCTGAAATGCTGGTTGCAGAAGGTGGCTCAGCCGGTGGC
ATGCTGATGGGCGCCATCGCCAACATGGCCGGTGACCGCTTCAAGGCGATCGAAGCCAACGTGCCATTCGTCGATCCGCT
GACCTCTATGCTCATGCCGGAACTGCCACTGACGGTTATCGAATGGGATGAGTGGGGCGATCCACTCCACGATAAGGACG
TCTATGAATACATGGCGTCCTATGCCCCATATGAAAACATCGAGGCAAAGAACTACCCCAATATCTTGGCCGTAACATCG
CTCAACGACACCCGAGTGTTGTACGTCGAACCAGCCAAATGGGTAGCGCAGCTTCGGGCGACTGCAACCGGTGGAGAGTT
CCTTCTGAAAACTGAAATGGTTGCCGGACACGGCGGTGTGTCAGGACGCTACGAAAAGTGGCGTGAGACTGCATTTGAGT
ACGGCTGGTTGATCAACCAAGCAACTGGTGTGACCGAATAA

Upstream 100 bases:

>100_bases
AAATGAATCCGGGTTTTTCAGTTTCGGGGTGCAAATCAGAATGTCGCCAATGGCGAACACACGAGCGTACAGAAGATGTG
CGTGACTAAGATCGGGGGCT

Downstream 100 bases:

>100_bases
AACTTGTTCGACTAGCGAACTTTAAATCACCCTCGGCGACTTTAGCGGGGGTGATTTATTCTTTTTCGGGGGTTTGGGTA
CGAGCGGAGAAATTTGGGCT

Product: hypothetical protein

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 706; Mature: 705

Protein sequence:

>706_residues
MSERLNAPQAPIHPITRTHHGIDFVDNYEWLRDKESQETLDYLEAENAFTKQETEQLATLRDNIYEEIKSRVKETDMSIP
VRAGKYWYYSRTEEGKSYGYSCRIPVTEGSDAWTPPVIPEGEPAQGETIIMDANELAEGHEFFSMGASSVTTSGRYLAYS
TDVTGEERFTLRIKDLETGELLPDTLTGIFYGATWVGEEYLFYQRVDDAWRPDTVWRHKVGTPVEEDVLVYHEPDERYST
WVGTTRSEKFILFGCASKITSEVRVLPFDQPEGTPEVLIPRAEGVEYDVDHAVVDGSDIWLVTHNAEGPNFSVGWAGVDK
LNSLDALTPLVAHKDDVRIEGVDTYRDFIILGYRSGAIGQVAIMKLIDGTFGEFQQLEFDEEIYTVASGGNPEWDAPVIR
LSYGSFTTPAQLFNYWIESGERTLLKQQEVLGGYNPSDYVASRLWVTAKDGAQIPVSLVHRTDLDVSKPNPALLYGYGSY
ESSIDPGFSIARLSLMDRGMIFAIAHVRGGGEMGRGWYDNGKTTTKKNTFTDFIDVADALIEQKISAPEMLVAEGGSAGG
MLMGAIANMAGDRFKAIEANVPFVDPLTSMLMPELPLTVIEWDEWGDPLHDKDVYEYMASYAPYENIEAKNYPNILAVTS
LNDTRVLYVEPAKWVAQLRATATGGEFLLKTEMVAGHGGVSGRYEKWRETAFEYGWLINQATGVTE

Sequences:

>Translated_706_residues
MSERLNAPQAPIHPITRTHHGIDFVDNYEWLRDKESQETLDYLEAENAFTKQETEQLATLRDNIYEEIKSRVKETDMSIP
VRAGKYWYYSRTEEGKSYGYSCRIPVTEGSDAWTPPVIPEGEPAQGETIIMDANELAEGHEFFSMGASSVTTSGRYLAYS
TDVTGEERFTLRIKDLETGELLPDTLTGIFYGATWVGEEYLFYQRVDDAWRPDTVWRHKVGTPVEEDVLVYHEPDERYST
WVGTTRSEKFILFGCASKITSEVRVLPFDQPEGTPEVLIPRAEGVEYDVDHAVVDGSDIWLVTHNAEGPNFSVGWAGVDK
LNSLDALTPLVAHKDDVRIEGVDTYRDFIILGYRSGAIGQVAIMKLIDGTFGEFQQLEFDEEIYTVASGGNPEWDAPVIR
LSYGSFTTPAQLFNYWIESGERTLLKQQEVLGGYNPSDYVASRLWVTAKDGAQIPVSLVHRTDLDVSKPNPALLYGYGSY
ESSIDPGFSIARLSLMDRGMIFAIAHVRGGGEMGRGWYDNGKTTTKKNTFTDFIDVADALIEQKISAPEMLVAEGGSAGG
MLMGAIANMAGDRFKAIEANVPFVDPLTSMLMPELPLTVIEWDEWGDPLHDKDVYEYMASYAPYENIEAKNYPNILAVTS
LNDTRVLYVEPAKWVAQLRATATGGEFLLKTEMVAGHGGVSGRYEKWRETAFEYGWLINQATGVTE
>Mature_705_residues
SERLNAPQAPIHPITRTHHGIDFVDNYEWLRDKESQETLDYLEAENAFTKQETEQLATLRDNIYEEIKSRVKETDMSIPV
RAGKYWYYSRTEEGKSYGYSCRIPVTEGSDAWTPPVIPEGEPAQGETIIMDANELAEGHEFFSMGASSVTTSGRYLAYST
DVTGEERFTLRIKDLETGELLPDTLTGIFYGATWVGEEYLFYQRVDDAWRPDTVWRHKVGTPVEEDVLVYHEPDERYSTW
VGTTRSEKFILFGCASKITSEVRVLPFDQPEGTPEVLIPRAEGVEYDVDHAVVDGSDIWLVTHNAEGPNFSVGWAGVDKL
NSLDALTPLVAHKDDVRIEGVDTYRDFIILGYRSGAIGQVAIMKLIDGTFGEFQQLEFDEEIYTVASGGNPEWDAPVIRL
SYGSFTTPAQLFNYWIESGERTLLKQQEVLGGYNPSDYVASRLWVTAKDGAQIPVSLVHRTDLDVSKPNPALLYGYGSYE
SSIDPGFSIARLSLMDRGMIFAIAHVRGGGEMGRGWYDNGKTTTKKNTFTDFIDVADALIEQKISAPEMLVAEGGSAGGM
LMGAIANMAGDRFKAIEANVPFVDPLTSMLMPELPLTVIEWDEWGDPLHDKDVYEYMASYAPYENIEAKNYPNILAVTSL
NDTRVLYVEPAKWVAQLRATATGGEFLLKTEMVAGHGGVSGRYEKWRETAFEYGWLINQATGVTE

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=706, Percent_Identity=25.9206798866856, Blast_Score=184, Evalue=4e-46,
Organism=Homo sapiens, GI284172420, Length=460, Percent_Identity=27.8260869565217, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI284172413, Length=460, Percent_Identity=27.8260869565217, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI70778815, Length=460, Percent_Identity=27.8260869565217, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI284172438, Length=460, Percent_Identity=27.8260869565217, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI284172431, Length=460, Percent_Identity=27.8260869565217, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI108860686, Length=204, Percent_Identity=37.2549019607843, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI108860692, Length=200, Percent_Identity=37, Blast_Score=131, Evalue=2e-30,
Organism=Escherichia coli, GI1788150, Length=702, Percent_Identity=37.037037037037, Blast_Score=458, Evalue=1e-130,
Organism=Drosophila melanogaster, GI24583414, Length=727, Percent_Identity=26.4099037138927, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI221510989, Length=711, Percent_Identity=24.3319268635724, Blast_Score=177, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78947; Mature: 78816

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLNAPQAPIHPITRTHHGIDFVDNYEWLRDKESQETLDYLEAENAFTKQETEQLATL
CCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
RDNIYEEIKSRVKETDMSIPVRAGKYWYYSRTEEGKSYGYSCRIPVTEGSDAWTPPVIPE
HHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCC
GEPAQGETIIMDANELAEGHEFFSMGASSVTTSGRYLAYSTDVTGEERFTLRIKDLETGE
CCCCCCCEEEEECHHHHCCHHHHHCCCCCEECCCEEEEEECCCCCCCEEEEEEEECCCCC
LLPDTLTGIFYGATWVGEEYLFYQRVDDAWRPDTVWRHKVGTPVEEDVLVYHEPDERYST
CCHHHHHHHHHCHHHCCCHHHEEEHHCCCCCCCCHHHHCCCCCCCCCEEEEECCCCHHHH
WVGTTRSEKFILFGCASKITSEVRVLPFDQPEGTPEVLIPRAEGVEYDVDHAVVDGSDIW
HCCCCCCCEEEEEECCHHHCCCEEEEECCCCCCCCCEEEECCCCCEEECCEEEECCCEEE
LVTHNAEGPNFSVGWAGVDKLNSLDALTPLVAHKDDVRIEGVDTYRDFIILGYRSGAIGQ
EEEECCCCCCEEECCCCHHHCCCHHHHHHHHCCCCCCEEEEECCCEEEEEEEECCCCCHH
VAIMKLIDGTFGEFQQLEFDEEIYTVASGGNPEWDAPVIRLSYGSFTTPAQLFNYWIESG
HHHHHHHCCCCCHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCC
ERTLLKQQEVLGGYNPSDYVASRLWVTAKDGAQIPVSLVHRTDLDVSKPNPALLYGYGSY
CHHHHHHHHHHCCCCCHHHHHHEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCC
ESSIDPGFSIARLSLMDRGMIFAIAHVRGGGEMGRGWYDNGKTTTKKNTFTDFIDVADAL
CCCCCCCCCEEHHHHHCCCEEEEEEEECCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHH
IEQKISAPEMLVAEGGSAGGMLMGAIANMAGDRFKAIEANVPFVDPLTSMLMPELPLTVI
HHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCEEEE
EWDEWGDPLHDKDVYEYMASYAPYENIEAKNYPNILAVTSLNDTRVLYVEPAKWVAQLRA
EECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHH
TATGGEFLLKTEMVAGHGGVSGRYEKWRETAFEYGWLINQATGVTE
CCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure 
SERLNAPQAPIHPITRTHHGIDFVDNYEWLRDKESQETLDYLEAENAFTKQETEQLATL
CCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
RDNIYEEIKSRVKETDMSIPVRAGKYWYYSRTEEGKSYGYSCRIPVTEGSDAWTPPVIPE
HHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCC
GEPAQGETIIMDANELAEGHEFFSMGASSVTTSGRYLAYSTDVTGEERFTLRIKDLETGE
CCCCCCCEEEEECHHHHCCHHHHHCCCCCEECCCEEEEEECCCCCCCEEEEEEEECCCCC
LLPDTLTGIFYGATWVGEEYLFYQRVDDAWRPDTVWRHKVGTPVEEDVLVYHEPDERYST
CCHHHHHHHHHCHHHCCCHHHEEEHHCCCCCCCCHHHHCCCCCCCCCEEEEECCCCHHHH
WVGTTRSEKFILFGCASKITSEVRVLPFDQPEGTPEVLIPRAEGVEYDVDHAVVDGSDIW
HCCCCCCCEEEEEECCHHHCCCEEEEECCCCCCCCCEEEECCCCCEEECCEEEECCCEEE
LVTHNAEGPNFSVGWAGVDKLNSLDALTPLVAHKDDVRIEGVDTYRDFIILGYRSGAIGQ
EEEECCCCCCEEECCCCHHHCCCHHHHHHHHCCCCCCEEEEECCCEEEEEEEECCCCCHH
VAIMKLIDGTFGEFQQLEFDEEIYTVASGGNPEWDAPVIRLSYGSFTTPAQLFNYWIESG
HHHHHHHCCCCCHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCC
ERTLLKQQEVLGGYNPSDYVASRLWVTAKDGAQIPVSLVHRTDLDVSKPNPALLYGYGSY
CHHHHHHHHHHCCCCCHHHHHHEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCC
ESSIDPGFSIARLSLMDRGMIFAIAHVRGGGEMGRGWYDNGKTTTKKNTFTDFIDVADAL
CCCCCCCCCEEHHHHHCCCEEEEEEEECCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHH
IEQKISAPEMLVAEGGSAGGMLMGAIANMAGDRFKAIEANVPFVDPLTSMLMPELPLTVI
HHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCEEEE
EWDEWGDPLHDKDVYEYMASYAPYENIEAKNYPNILAVTSLNDTRVLYVEPAKWVAQLRA
EECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHH
TATGGEFLLKTEMVAGHGGVSGRYEKWRETAFEYGWLINQATGVTE
CCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]