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The map label for this gene is dagK [H]

Identifier: 145296573

GI number: 145296573

Start: 2738545

End: 2739663

Strand: Reverse

Name: dagK [H]

Synonym: cgR_2481

Alternate gene names: 145296573

Gene position: 2739663-2738545 (Counterclockwise)

Preceding gene: 145296575

Following gene: 145296571

Centisome position: 82.66

GC content: 53.8

Gene sequence:

>1119_bases
ATGACACTCAAGACTAGCGTTTTGGCACTAGTCTTAGACAACGTGCATGTTCTTCTGATTGCGAATCCTGAGTCGACCAC
GCAGACGCAGAAACTTTTCCGTCGAGTGGTGCCTGAGTTGATGGCGCTTGATGGTGTGTCGCTTGAAGCGAGGTTTACGC
ACTATGGAGGCCATGCGGAGGAAATGGTCGCGGGTTTGACGGTGGATGATTTTGATGTGATTATCCCCGCGGGTGGGGAC
GGCACCGTCAACGAAGTGATAAATGGGTTACTTGGTTCGGCGGAAGGTGATTTTAGAAACCTTGAGGATTTGCCGGCGAT
TGCGGTGTTGCCAACGGGGTCTGCCAATGTGTTTGCCCGCGCTCTGGGGTATCCCACTGATCCGTATGCTGCGGCTGATG
CCCTGGTGGAGTTGATCCGGAAGAACCACACCAGAACCATCACCTTGGGTACGTGGAAAGGTGATGATCAGGAGACTCGT
TGGTTCGCGGTGAACGCTGGTTTTGGCATTGACGCGGATGTTATTGCGAGGGTCGAGAGGGCCCGTTCGTTCGGGTTTGC
GGCTTCGCCGTTGTTGTATCTGCAGGTGAGTCTTCGGGCGTGGGTGAAAACTCAAATTAAGCCACCGAAGATTACCGTGG
AGGCGGTGGACAGTGCAGGGCACGAATTACATAAAGAGGATGTGCCCATGCTGCTTGCTTCCAACACTAATCCGTGGACT
TTCTTGGGGCCGCTGCCGGTGGTGACAAATCCGGAGAATTCTTTTGACACAGGTCTTGGGCTTTTCGGATTGACCAAGGT
GCGGGGATTTGGGGGAGTGGCAGCGATGATGCACCTGATTGGCGTGGGGCATGGTCGGAAGTTGGAGAAGTTGATCGCTA
AGCGCACCATTGCTTTTGATGATGCGGAGAAAGTAACGCTCACGTGCGACAGCGATCAGCGTTTCCAAGTTGATGGTGAG
TATGAAGGCAAACCAACAAAGGTGGTGTTGGAATCAATCACTGATGCGGTGCGAGTGTATGCGCCGAAGACGCATCCGAC
ACCGCCGATCATGAATTGGGCTGTCCATCTGTTTAAGCACGTCCGTGATTTCCTCCGGGTGCGCACGTTTGGCATCTAG

Upstream 100 bases:

>100_bases
GACTGCGTCGGATCCGCTGATGCTTGCAGAATCGGACAGCGATGGACCGTCTGCGCCTGCACCTGGGACGACTGGATTGT
TAGGGGTGGAATTTTCGCTC

Downstream 100 bases:

>100_bases
GATTCATCGGAGTTTTCTTCCGGTGCAGCTAGTGGTGATAGTTCGCGGGTGGTGAGCTGGACGTTGCGGGCTTCAGATTG
GAAATGGACGGAGCCACCAG

Product: hypothetical protein

Products: NA

Alternate protein names: DAG kinase; DAGK [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTLKTSVLALVLDNVHVLLIANPESTTQTQKLFRRVVPELMALDGVSLEARFTHYGGHAEEMVAGLTVDDFDVIIPAGGD
GTVNEVINGLLGSAEGDFRNLEDLPAIAVLPTGSANVFARALGYPTDPYAAADALVELIRKNHTRTITLGTWKGDDQETR
WFAVNAGFGIDADVIARVERARSFGFAASPLLYLQVSLRAWVKTQIKPPKITVEAVDSAGHELHKEDVPMLLASNTNPWT
FLGPLPVVTNPENSFDTGLGLFGLTKVRGFGGVAAMMHLIGVGHGRKLEKLIAKRTIAFDDAEKVTLTCDSDQRFQVDGE
YEGKPTKVVLESITDAVRVYAPKTHPTPPIMNWAVHLFKHVRDFLRVRTFGI

Sequences:

>Translated_372_residues
MTLKTSVLALVLDNVHVLLIANPESTTQTQKLFRRVVPELMALDGVSLEARFTHYGGHAEEMVAGLTVDDFDVIIPAGGD
GTVNEVINGLLGSAEGDFRNLEDLPAIAVLPTGSANVFARALGYPTDPYAAADALVELIRKNHTRTITLGTWKGDDQETR
WFAVNAGFGIDADVIARVERARSFGFAASPLLYLQVSLRAWVKTQIKPPKITVEAVDSAGHELHKEDVPMLLASNTNPWT
FLGPLPVVTNPENSFDTGLGLFGLTKVRGFGGVAAMMHLIGVGHGRKLEKLIAKRTIAFDDAEKVTLTCDSDQRFQVDGE
YEGKPTKVVLESITDAVRVYAPKTHPTPPIMNWAVHLFKHVRDFLRVRTFGI
>Mature_371_residues
TLKTSVLALVLDNVHVLLIANPESTTQTQKLFRRVVPELMALDGVSLEARFTHYGGHAEEMVAGLTVDDFDVIIPAGGDG
TVNEVINGLLGSAEGDFRNLEDLPAIAVLPTGSANVFARALGYPTDPYAAADALVELIRKNHTRTITLGTWKGDDQETRW
FAVNAGFGIDADVIARVERARSFGFAASPLLYLQVSLRAWVKTQIKPPKITVEAVDSAGHELHKEDVPMLLASNTNPWTF
LGPLPVVTNPENSFDTGLGLFGLTKVRGFGGVAAMMHLIGVGHGRKLEKLIAKRTIAFDDAEKVTLTCDSDQRFQVDGEY
EGKPTKVVLESITDAVRVYAPKTHPTPPIMNWAVHLFKHVRDFLRVRTFGI

Specific function: Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthet

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: =2.7.1.107 [H]

Molecular weight: Translated: 40575; Mature: 40444

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKTSVLALVLDNVHVLLIANPESTTQTQKLFRRVVPELMALDGVSLEARFTHYGGHAE
CCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHH
EMVAGLTVDDFDVIIPAGGDGTVNEVINGLLGSAEGDFRNLEDLPAIAVLPTGSANVFAR
HHHHCCEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHCCEEEEEECCCHHHHHH
ALGYPTDPYAAADALVELIRKNHTRTITLGTWKGDDQETRWFAVNAGFGIDADVIARVER
HHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHH
ARSFGFAASPLLYLQVSLRAWVKTQIKPPKITVEAVDSAGHELHKEDVPMLLASNTNPWT
HHHCCCCCCCCEEEEEHHHHHHHHCCCCCEEEEEECCCCCHHHCCCCCCEEEECCCCCEE
FLGPLPVVTNPENSFDTGLGLFGLTKVRGFGGVAAMMHLIGVGHGRKLEKLIAKRTIAFD
EECCCCEEECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHEEEC
DAEKVTLTCDSDQRFQVDGEYEGKPTKVVLESITDAVRVYAPKTHPTPPIMNWAVHLFKH
CCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHH
VRDFLRVRTFGI
HHHHHHHHHCCC
>Mature Secondary Structure 
TLKTSVLALVLDNVHVLLIANPESTTQTQKLFRRVVPELMALDGVSLEARFTHYGGHAE
CCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHH
EMVAGLTVDDFDVIIPAGGDGTVNEVINGLLGSAEGDFRNLEDLPAIAVLPTGSANVFAR
HHHHCCEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHCCEEEEEECCCHHHHHH
ALGYPTDPYAAADALVELIRKNHTRTITLGTWKGDDQETRWFAVNAGFGIDADVIARVER
HHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHH
ARSFGFAASPLLYLQVSLRAWVKTQIKPPKITVEAVDSAGHELHKEDVPMLLASNTNPWT
HHHCCCCCCCCEEEEEHHHHHHHHCCCCCEEEEEECCCCCHHHCCCCCCEEEECCCCCEE
FLGPLPVVTNPENSFDTGLGLFGLTKVRGFGGVAAMMHLIGVGHGRKLEKLIAKRTIAFD
EECCCCEEECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHEEEC
DAEKVTLTCDSDQRFQVDGEYEGKPTKVVLESITDAVRVYAPKTHPTPPIMNWAVHLFKH
CCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHH
VRDFLRVRTFGI
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA