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The map label for this gene is mshD

Identifier: 145296571

GI number: 145296571

Start: 2736825

End: 2737703

Strand: Reverse

Name: mshD

Synonym: cgR_2479

Alternate gene names: 145296571

Gene position: 2737703-2736825 (Counterclockwise)

Preceding gene: 145296573

Following gene: 145296570

Centisome position: 82.61

GC content: 52.9

Gene sequence:

>879_bases
ATGAATACTTCCGATCGTATTAAAAGCACTCAAATCGCGCTGGATCGTGACCTCCGTGAGCAGGCACTATTGCTTTTGAA
GGAGGTTCGCGCAGTTGATGGCGTGGATGCTTTCTCAGAACAATTTGTCCGTGGGCTTGCAGAACCCGGACTTGGTCACT
CCCATTTAATAGTCACGCTCAATGACAAACTGGTTGGCCTCGCGGCCACGGATGAGGAAACCACGGAACTGGCTGTCCAC
CCGGCGCACAGGCGTCAGGGAATTGGTAAGGCGCTTATCGACGCCGCCCCCACCTCATCAATCTGGGCGCATGGAAATAC
CGCAGGTGCACAAGCGTTGGCATCCACCCTGCGTATGAAGAAGACTCGCGAGCTTCTGGTGATGGAGATTTCCGACAGGG
CGCTCGATGGCTCTGCAGCATACAAAGATCCAGATGGAATTACACACAGTAGTTTGGCGAATGCCCCTGTGGAGAAATCA
GTAGCTGAGGCTAAATGGCTTCAATCCAACAACGAAGCATTTGACTGGCATCCCGAGCAGGGCGGATGGACAACTCATCG
GTTGGCGCAGGCTCAGAAAGCCGATTGGTACAAGGACTCTGACGTGTTATTCCTCTGGGACGGCGAAGAGATCGTTGGCT
TCCACTGGGTAAAGCAGCACAGTCCAGAATTACAAGAGATTTACGTAGTTGGCCTTTCTTCAGCCTACCGTGGTCGCGGC
TTGGGAGATCCGCTTGTTCGCCTCGGACTGCATCACATGAGGGCTCATGGTGCTCGAAAAGTGATTCTTTATGTGGAAGC
TGACAACACTCCGGCAGTCGCGGCATACGAAAAACTGGGATTCACTGTCGCGGAAAGCCACGTAGTTTACGAAAAGTAA

Upstream 100 bases:

>100_bases
GATGCTGCGATGGTCACAAGTCGTTTTCTGGATTTTTCCACATCTATATCTTTACCCCACGTTCCTGCAAGAGATTCAAA
CTTGGGGCTAACCTGGGGAC

Downstream 100 bases:

>100_bases
AAAAGAGACTTGCTAAAAACCTGTGAGAATAATAAGAATCGGTGATTTTCGTTTCGGAGGGGTCGAAAATTGCCGATTTT
TGTGATCGGAGTCTCCAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: MSH acetyltransferase; Mycothiol synthase

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MNTSDRIKSTQIALDRDLREQALLLLKEVRAVDGVDAFSEQFVRGLAEPGLGHSHLIVTLNDKLVGLAATDEETTELAVH
PAHRRQGIGKALIDAAPTSSIWAHGNTAGAQALASTLRMKKTRELLVMEISDRALDGSAAYKDPDGITHSSLANAPVEKS
VAEAKWLQSNNEAFDWHPEQGGWTTHRLAQAQKADWYKDSDVLFLWDGEEIVGFHWVKQHSPELQEIYVVGLSSAYRGRG
LGDPLVRLGLHHMRAHGARKVILYVEADNTPAVAAYEKLGFTVAESHVVYEK

Sequences:

>Translated_292_residues
MNTSDRIKSTQIALDRDLREQALLLLKEVRAVDGVDAFSEQFVRGLAEPGLGHSHLIVTLNDKLVGLAATDEETTELAVH
PAHRRQGIGKALIDAAPTSSIWAHGNTAGAQALASTLRMKKTRELLVMEISDRALDGSAAYKDPDGITHSSLANAPVEKS
VAEAKWLQSNNEAFDWHPEQGGWTTHRLAQAQKADWYKDSDVLFLWDGEEIVGFHWVKQHSPELQEIYVVGLSSAYRGRG
LGDPLVRLGLHHMRAHGARKVILYVEADNTPAVAAYEKLGFTVAESHVVYEK
>Mature_292_residues
MNTSDRIKSTQIALDRDLREQALLLLKEVRAVDGVDAFSEQFVRGLAEPGLGHSHLIVTLNDKLVGLAATDEETTELAVH
PAHRRQGIGKALIDAAPTSSIWAHGNTAGAQALASTLRMKKTRELLVMEISDRALDGSAAYKDPDGITHSSLANAPVEKS
VAEAKWLQSNNEAFDWHPEQGGWTTHRLAQAQKADWYKDSDVLFLWDGEEIVGFHWVKQHSPELQEIYVVGLSSAYRGRG
LGDPLVRLGLHHMRAHGARKVILYVEADNTPAVAAYEKLGFTVAESHVVYEK

Specific function: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol

COG id: COG0456

COG function: function code R; Acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 N-acetyltransferase domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSHD_CORGB (A4QGX4)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001139392.1
- ProteinModelPortal:   A4QGX4
- SMR:   A4QGX4
- STRING:   A4QGX4
- GeneID:   4993380
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_2479
- eggNOG:   COG0456
- HOGENOM:   HBG292446
- OMA:   GFHWTKI
- ProtClustDB:   CLSK633864
- HAMAP:   MF_01698
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR017813
- Gene3D:   G3DSA:3.40.630.30
- TIGRFAMs:   TIGR03448

Pfam domain/function: PF00583 Acetyltransf_1; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.189

Molecular weight: Translated: 32139; Mature: 32139

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS51186 GNAT

Important sites: BINDING 40-40 BINDING 179-179 BINDING 218-218 BINDING 226-226 BINDING 264-264

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSDRIKSTQIALDRDLREQALLLLKEVRAVDGVDAFSEQFVRGLAEPGLGHSHLIVTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEE
NDKLVGLAATDEETTELAVHPAHRRQGIGKALIDAAPTSSIWAHGNTAGAQALASTLRMK
CCCEEEEEECCCCCCEEEECCHHHHCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHH
KTRELLVMEISDRALDGSAAYKDPDGITHSSLANAPVEKSVAEAKWLQSNNEAFDWHPEQ
HHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
GGWTTHRLAQAQKADWYKDSDVLFLWDGEEIVGFHWVKQHSPELQEIYVVGLSSAYRGRG
CCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEEHHHCCCCCEEEEEEECCHHCCCCC
LGDPLVRLGLHHMRAHGARKVILYVEADNTPAVAAYEKLGFTVAESHVVYEK
CCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHCCEEECCEEEECC
>Mature Secondary Structure
MNTSDRIKSTQIALDRDLREQALLLLKEVRAVDGVDAFSEQFVRGLAEPGLGHSHLIVTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEE
NDKLVGLAATDEETTELAVHPAHRRQGIGKALIDAAPTSSIWAHGNTAGAQALASTLRMK
CCCEEEEEECCCCCCEEEECCHHHHCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHH
KTRELLVMEISDRALDGSAAYKDPDGITHSSLANAPVEKSVAEAKWLQSNNEAFDWHPEQ
HHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
GGWTTHRLAQAQKADWYKDSDVLFLWDGEEIVGFHWVKQHSPELQEIYVVGLSSAYRGRG
CCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEEHHHCCCCCEEEEEEECCHHCCCCC
LGDPLVRLGLHHMRAHGARKVILYVEADNTPAVAAYEKLGFTVAESHVVYEK
CCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHCCEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA