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The map label for this gene is argD [H]

Identifier: 145296429

GI number: 145296429

Start: 2578567

End: 2579937

Strand: Direct

Name: argD [H]

Synonym: cgR_2343

Alternate gene names: 145296429

Gene position: 2578567-2579937 (Clockwise)

Preceding gene: 145296428

Following gene: 145296430

Centisome position: 77.8

GC content: 57.11

Gene sequence:

>1371_bases
TTGACACTGAAGGGTTACACCAACTTTGACGGTGAATTCATCGAATTCGGATCTGCGCAAGCAAAAGAAGAGGAAAAACG
GGCATTCGACAACGATCGCGCACACGTTTTCCACTCCTGGTCCGCGCAGGACAAAATCAGCCCCAAAGTATGGGCAGCTG
CCGAAGGTTCCACGCTGTACGACTTCGACGGTAACGCCTTCATCGACATGGGTTCCCAACTTGTCTCGGCAAACTTAGGC
CACAACAACCCCCGCTTGGTCGAGGCGATCCAGCGCCAAGCAGCCCGGTTGACCAACATCAACCCGGCTTTCGGAAACGA
TGTGCGCTCTGATGTTGCTGCAAAGATCGTGTCGATGGCCCGTGGCGAATTCTCCCACGTGTTTTTCACCAACGGCGGCG
CCGACGCCATCGAACACTCCATCCGCATGGCTCGCCTGCACACCGGACGCAACAAAATTCTGTCCGCATACCGCAGCTAC
CACGGCGCAACCGGATCCGCGATGATGCTCACCGGCGAACACCGCCGCCTGGGCAACCCCACCACCGACCCAGATATCTA
CCACTTCTGGGCACCATTCCTGCACCACTCCTCATTCTTTGCCACCACCCAAGAAGAAGAATGCGAACGCGCACTCAAGC
ACTTGGAAGATGTCATCGCGTTTGAAGGTGCTGGCATGATCGCAGCGATCGTGTTGGAACCAGTGGTGGGATCCTCAGGA
ATCATCGTGCCACCAGCAGGCTACTTGAATGGCGTGCGCGAACTTTGCAATAAGCACGGCATCCTCTTCATCGCCGACGA
AGTCATGGTCGGATTCGGACGCACCGGAAAACTGTTTGCTTACGAGCACGCCGGCGACGACTTCCAGCCAGACATGATCA
CCTTCGCCAAGGGCGTTAACGCAGGCTACGCCCCACTCGGTGGCATCGTGATGACCCAGGAAATCCGCGACACTTTCGGA
TCAGAGGCATACTCCGGCGGACTCACCTACTCCGGACACCCATTGGCAGTAGCACCTGCCAAGGCAGCGCTGGAGATTTA
CGCGGAAGGTGAAATCATTCCACGCGTAGCTCGACTAGGCGCTGAAATGATCGGACCTCGCCTTCGAGAACTAGCGGAAG
AAAACGTGGCGATCGCTGATGTGCGAGGCATCGGCTTCTTCTGGGCGGTGGAGTTCAATGCAGACGCCACTGCCATGAAT
GCAGGTGCTGCAGAATTCAAGGAACGCGGCGTGTGGCCGATGATCTCCGGCAACCGATTCCACATTGCACCGCCGCTGAC
CACCACTGATGACGAATTAGTAGCACTACTGGACGCGGTGGAAGCTGCAGCCCAAGCTGTCGAGCTGACCTTCGCTGGGG
CGTTGTTCTAA

Upstream 100 bases:

>100_bases
AACCGACAAAACAGCCGTTCACGTGCTAAAGCAGCTCGGCTTGATCTAGGGTGAGGTGAGTTATTTAAAGACTGCATAAT
ATTTTGGGGAGTGAACTGGT

Downstream 100 bases:

>100_bases
GTTTTAGATAACAAGACCAGCACAGACCACCATATCTACGACCCCAAAAACAGACTCCAAGCTCCGCGGCGACGAAGCCG
CGCTCGCGCCACCGACCAAG

Product: hypothetical protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTLKGYTNFDGEFIEFGSAQAKEEEKRAFDNDRAHVFHSWSAQDKISPKVWAAAEGSTLYDFDGNAFIDMGSQLVSANLG
HNNPRLVEAIQRQAARLTNINPAFGNDVRSDVAAKIVSMARGEFSHVFFTNGGADAIEHSIRMARLHTGRNKILSAYRSY
HGATGSAMMLTGEHRRLGNPTTDPDIYHFWAPFLHHSSFFATTQEEECERALKHLEDVIAFEGAGMIAAIVLEPVVGSSG
IIVPPAGYLNGVRELCNKHGILFIADEVMVGFGRTGKLFAYEHAGDDFQPDMITFAKGVNAGYAPLGGIVMTQEIRDTFG
SEAYSGGLTYSGHPLAVAPAKAALEIYAEGEIIPRVARLGAEMIGPRLRELAEENVAIADVRGIGFFWAVEFNADATAMN
AGAAEFKERGVWPMISGNRFHIAPPLTTTDDELVALLDAVEAAAQAVELTFAGALF

Sequences:

>Translated_456_residues
MTLKGYTNFDGEFIEFGSAQAKEEEKRAFDNDRAHVFHSWSAQDKISPKVWAAAEGSTLYDFDGNAFIDMGSQLVSANLG
HNNPRLVEAIQRQAARLTNINPAFGNDVRSDVAAKIVSMARGEFSHVFFTNGGADAIEHSIRMARLHTGRNKILSAYRSY
HGATGSAMMLTGEHRRLGNPTTDPDIYHFWAPFLHHSSFFATTQEEECERALKHLEDVIAFEGAGMIAAIVLEPVVGSSG
IIVPPAGYLNGVRELCNKHGILFIADEVMVGFGRTGKLFAYEHAGDDFQPDMITFAKGVNAGYAPLGGIVMTQEIRDTFG
SEAYSGGLTYSGHPLAVAPAKAALEIYAEGEIIPRVARLGAEMIGPRLRELAEENVAIADVRGIGFFWAVEFNADATAMN
AGAAEFKERGVWPMISGNRFHIAPPLTTTDDELVALLDAVEAAAQAVELTFAGALF
>Mature_455_residues
TLKGYTNFDGEFIEFGSAQAKEEEKRAFDNDRAHVFHSWSAQDKISPKVWAAAEGSTLYDFDGNAFIDMGSQLVSANLGH
NNPRLVEAIQRQAARLTNINPAFGNDVRSDVAAKIVSMARGEFSHVFFTNGGADAIEHSIRMARLHTGRNKILSAYRSYH
GATGSAMMLTGEHRRLGNPTTDPDIYHFWAPFLHHSSFFATTQEEECERALKHLEDVIAFEGAGMIAAIVLEPVVGSSGI
IVPPAGYLNGVRELCNKHGILFIADEVMVGFGRTGKLFAYEHAGDDFQPDMITFAKGVNAGYAPLGGIVMTQEIRDTFGS
EAYSGGLTYSGHPLAVAPAKAALEIYAEGEIIPRVARLGAEMIGPRLRELAEENVAIADVRGIGFFWAVEFNADATAMNA
GAAEFKERGVWPMISGNRFHIAPPLTTTDDELVALLDAVEAAAQAVELTFAGALF

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=28.6729857819905, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI4557809, Length=390, Percent_Identity=28.7179487179487, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=29.4117647058824, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=28.1990521327014, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI13994255, Length=403, Percent_Identity=26.7990074441687, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=27.3381294964029, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI284507298, Length=314, Percent_Identity=28.9808917197452, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI188536080, Length=383, Percent_Identity=25.065274151436, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38679950, Length=383, Percent_Identity=25.065274151436, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38679946, Length=383, Percent_Identity=25.065274151436, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI145693181, Length=408, Percent_Identity=29.9019607843137, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1787560, Length=412, Percent_Identity=35.4368932038835, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1788044, Length=412, Percent_Identity=28.8834951456311, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786991, Length=438, Percent_Identity=29.9086757990868, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1789016, Length=403, Percent_Identity=27.7915632754342, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1789759, Length=410, Percent_Identity=27.8048780487805, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786349, Length=308, Percent_Identity=30.8441558441558, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=415, Percent_Identity=28.433734939759, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32564660, Length=420, Percent_Identity=29.2857142857143, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71992977, Length=460, Percent_Identity=28.695652173913, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=254, Percent_Identity=32.2834645669291, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=376, Percent_Identity=27.6595744680851, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323470, Length=423, Percent_Identity=30.4964539007092, Blast_Score=176, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6324432, Length=409, Percent_Identity=25.9168704156479, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324386, Length=467, Percent_Identity=23.5546038543897, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI161085790, Length=426, Percent_Identity=29.1079812206573, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28574759, Length=433, Percent_Identity=29.0993071593533, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI21357415, Length=416, Percent_Identity=27.4038461538462, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356575, Length=356, Percent_Identity=28.9325842696629, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281366494, Length=369, Percent_Identity=27.10027100271, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24667139, Length=369, Percent_Identity=27.10027100271, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24667143, Length=369, Percent_Identity=27.10027100271, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 49392; Mature: 49261

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKGYTNFDGEFIEFGSAQAKEEEKRAFDNDRAHVFHSWSAQDKISPKVWAAAEGSTLY
CCCCCCCCCCCHHEECCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCCCEEE
DFDGNAFIDMGSQLVSANLGHNNPRLVEAIQRQAARLTNINPAFGNDVRSDVAAKIVSMA
ECCCCEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RGEFSHVFFTNGGADAIEHSIRMARLHTGRNKILSAYRSYHGATGSAMMLTGEHRRLGNP
CCCCEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCHHCCCC
TTDPDIYHFWAPFLHHSSFFATTQEEECERALKHLEDVIAFEGAGMIAAIVLEPVVGSSG
CCCCCHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCC
IIVPPAGYLNGVRELCNKHGILFIADEVMVGFGRTGKLFAYEHAGDDFQPDMITFAKGVN
EEECCHHHHHHHHHHHHHCCEEEEECHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHCCC
AGYAPLGGIVMTQEIRDTFGSEAYSGGLTYSGHPLAVAPAKAALEIYAEGEIIPRVARLG
CCCCCCCCEEEHHHHHHHHCCCHHCCCCEECCCCEEEECCCEEEEEEECCCHHHHHHHHC
AEMIGPRLRELAEENVAIADVRGIGFFWAVEFNADATAMNAGAAEFKERGVWPMISGNRF
HHHHCHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCCCCCHHHHHHCCCCEEECCCEE
HIAPPLTTTDDELVALLDAVEAAAQAVELTFAGALF
EECCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
>Mature Secondary Structure 
TLKGYTNFDGEFIEFGSAQAKEEEKRAFDNDRAHVFHSWSAQDKISPKVWAAAEGSTLY
CCCCCCCCCCHHEECCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCCCEEE
DFDGNAFIDMGSQLVSANLGHNNPRLVEAIQRQAARLTNINPAFGNDVRSDVAAKIVSMA
ECCCCEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RGEFSHVFFTNGGADAIEHSIRMARLHTGRNKILSAYRSYHGATGSAMMLTGEHRRLGNP
CCCCEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCHHCCCC
TTDPDIYHFWAPFLHHSSFFATTQEEECERALKHLEDVIAFEGAGMIAAIVLEPVVGSSG
CCCCCHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCC
IIVPPAGYLNGVRELCNKHGILFIADEVMVGFGRTGKLFAYEHAGDDFQPDMITFAKGVN
EEECCHHHHHHHHHHHHHCCEEEEECHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHCCC
AGYAPLGGIVMTQEIRDTFGSEAYSGGLTYSGHPLAVAPAKAALEIYAEGEIIPRVARLG
CCCCCCCCEEEHHHHHHHHCCCHHCCCCEECCCCEEEECCCEEEEEEECCCHHHHHHHHC
AEMIGPRLRELAEENVAIADVRGIGFFWAVEFNADATAMNAGAAEFKERGVWPMISGNRF
HHHHCHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCCCCCHHHHHHCCCCEEECCCEE
HIAPPLTTTDDELVALLDAVEAAAQAVELTFAGALF
EECCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]