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The map label for this gene is gsiC [H]

Identifier: 145296426

GI number: 145296426

Start: 2573774

End: 2574715

Strand: Reverse

Name: gsiC [H]

Synonym: cgR_2340

Alternate gene names: 145296426

Gene position: 2574715-2573774 (Counterclockwise)

Preceding gene: 145296427

Following gene: 145296425

Centisome position: 77.69

GC content: 55.63

Gene sequence:

>942_bases
ATGACTACCTCGCAGATTCTGCGCCGCATCGGCCAAGCCGTCTTGGTCTTGTTGGTCACCTTTACCTTGGCGTTCATCAT
GCTTTCCGCCCTCCCTGGCGATGCTGTGTCCGCCCGCTATTCCAGCCCTGATTTGGGTCTGTCACCTGAGCAGATCGCAC
AGATCCGTGAATCCTATGGTGCCGATGAATCCCTGATCGCTCAGTACTTCTCCACCTTGGGTGGCTTCCTTGTAGGTAAC
TTCGGTTACTCCGTACAAACCGGAACTGCCGTGGCAACCCAGCTGGCAGAAGCCCTACCAGGCACCTTGACCTTGGCTAT
CTTGGCATTCTTGCTCGCAGCCATTTTGGCACTGGTTATTTCCATTCTTGCCACCATGGATCGCTTTGCATGGATCAAGG
GCATCTTCCAGGCTCTGCCTCCATTCTTTGTGTCCCTCCCAAGTTTCTGGTTGGGCATCATCTTGATCCAGATCGTATCC
TTCCGCCTTGGTTGGGTCCCCGTTATTGGGACCACCCCGGCACAAGGACTGATCCTGCCGACCATCACCTTGTCCATCCC
AATTGCCGCTCCGCTTGCACAGGTGCTCATCCGCTCGATTGAAGAGGTCAAGGCACAACCGTTCATCGCGGCTGTTCGTG
CTCGCGGTGCGGGTGAAATGTGGATCTTCTTCCGCAACATCATTCGCAACGCCCTGCTGCCAACCCTGACGATTGCCGGC
ATCTTGTTTGGTGAACTAGTCGGTGGGGCCGTGGTCACCGAGGCTGTGTTCGGCCGTGCTGGTCTTGGCCAAATGACCGT
CAACGCAGTGGCCAACCGCGATATGCCAGTGATGCTTGCCATCGTGGTAATTGCAGCTGCTGTTTATGTTTTGATCAACC
TCATCGTGGATTTGTTGTATCCAGTCCTCGATGCCCGTCTGCGCCGCAGGGAAAGGGCATAA

Upstream 100 bases:

>100_bases
GCCTTACGTGAAGGGCTTTAGCCCCGAAGTTATCGGCCGCCCCAGCTTCTATGAGACCTACATTGACCATTCCAGTAACG
ATTCCAGTGAGGAGGACTAA

Downstream 100 bases:

>100_bases
ATACCATGAGTAACCCTCCTATTTCATCTAAGAAACCGGTGTCTGCAAATCCTCGAACTGGATCAGCTGATCCGTCGCGC
AAGCGTAAAGCGTTGGGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTTSQILRRIGQAVLVLLVTFTLAFIMLSALPGDAVSARYSSPDLGLSPEQIAQIRESYGADESLIAQYFSTLGGFLVGN
FGYSVQTGTAVATQLAEALPGTLTLAILAFLLAAILALVISILATMDRFAWIKGIFQALPPFFVSLPSFWLGIILIQIVS
FRLGWVPVIGTTPAQGLILPTITLSIPIAAPLAQVLIRSIEEVKAQPFIAAVRARGAGEMWIFFRNIIRNALLPTLTIAG
ILFGELVGGAVVTEAVFGRAGLGQMTVNAVANRDMPVMLAIVVIAAAVYVLINLIVDLLYPVLDARLRRRERA

Sequences:

>Translated_313_residues
MTTSQILRRIGQAVLVLLVTFTLAFIMLSALPGDAVSARYSSPDLGLSPEQIAQIRESYGADESLIAQYFSTLGGFLVGN
FGYSVQTGTAVATQLAEALPGTLTLAILAFLLAAILALVISILATMDRFAWIKGIFQALPPFFVSLPSFWLGIILIQIVS
FRLGWVPVIGTTPAQGLILPTITLSIPIAAPLAQVLIRSIEEVKAQPFIAAVRARGAGEMWIFFRNIIRNALLPTLTIAG
ILFGELVGGAVVTEAVFGRAGLGQMTVNAVANRDMPVMLAIVVIAAAVYVLINLIVDLLYPVLDARLRRRERA
>Mature_312_residues
TTSQILRRIGQAVLVLLVTFTLAFIMLSALPGDAVSARYSSPDLGLSPEQIAQIRESYGADESLIAQYFSTLGGFLVGNF
GYSVQTGTAVATQLAEALPGTLTLAILAFLLAAILALVISILATMDRFAWIKGIFQALPPFFVSLPSFWLGIILIQIVSF
RLGWVPVIGTTPAQGLILPTITLSIPIAAPLAQVLIRSIEEVKAQPFIAAVRARGAGEMWIFFRNIIRNALLPTLTIAGI
LFGELVGGAVVTEAVFGRAGLGQMTVNAVANRDMPVMLAIVVIAAAVYVLINLIVDLLYPVLDARLRRRERA

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=311, Percent_Identity=32.475884244373, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=33.2278481012658, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=29.585798816568, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1787497, Length=306, Percent_Identity=31.3725490196078, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787550, Length=267, Percent_Identity=29.2134831460674, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787761, Length=316, Percent_Identity=28.1645569620253, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788504, Length=289, Percent_Identity=28.0276816608997, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33502; Mature: 33371

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSQILRRIGQAVLVLLVTFTLAFIMLSALPGDAVSARYSSPDLGLSPEQIAQIRESYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHC
ADESLIAQYFSTLGGFLVGNFGYSVQTGTAVATQLAEALPGTLTLAILAFLLAAILALVI
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SILATMDRFAWIKGIFQALPPFFVSLPSFWLGIILIQIVSFRLGWVPVIGTTPAQGLILP
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEHH
TITLSIPIAAPLAQVLIRSIEEVKAQPFIAAVRARGAGEMWIFFRNIIRNALLPTLTIAG
HHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ILFGELVGGAVVTEAVFGRAGLGQMTVNAVANRDMPVMLAIVVIAAAVYVLINLIVDLLY
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PVLDARLRRRERA
HHHHHHHHHHCCC
>Mature Secondary Structure 
TTSQILRRIGQAVLVLLVTFTLAFIMLSALPGDAVSARYSSPDLGLSPEQIAQIRESYG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHC
ADESLIAQYFSTLGGFLVGNFGYSVQTGTAVATQLAEALPGTLTLAILAFLLAAILALVI
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SILATMDRFAWIKGIFQALPPFFVSLPSFWLGIILIQIVSFRLGWVPVIGTTPAQGLILP
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEHH
TITLSIPIAAPLAQVLIRSIEEVKAQPFIAAVRARGAGEMWIFFRNIIRNALLPTLTIAG
HHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ILFGELVGGAVVTEAVFGRAGLGQMTVNAVANRDMPVMLAIVVIAAAVYVLINLIVDLLY
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PVLDARLRRRERA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA