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The map label for this gene is dppA [H]

Identifier: 145296427

GI number: 145296427

Start: 2574716

End: 2576425

Strand: Reverse

Name: dppA [H]

Synonym: cgR_2341

Alternate gene names: 145296427

Gene position: 2576425-2574716 (Counterclockwise)

Preceding gene: 145296432

Following gene: 145296426

Centisome position: 77.74

GC content: 54.91

Gene sequence:

>1710_bases
GTGTTTAAAAAGCACAGGCACGGTCTCGGCTCCCCCGAAACCAAACCACACTTAAAAACCCGCCGGTTTTTCACCGCGGC
TGCCGCTACGCTGGCAGGATTGGCAGTCCTGTCCGGCTGCACAGCACAACCCTCACAAGCAGAAGACAACACGCTCACTT
ACTTAGAGCCACAGTTCTTCCGCACCCTGTATCCACCATCAGCGGGCTTTTACCCCAACGGCAGTGTGGTGAACAACATT
GCAGACCGCTTGCTCTACCAGGATCCTGAAACCCTGGAACTCAAGCCATGGATCGCCACCGAACTGCCTGAAATCAACGA
GGATGCCACGGAGTTCACCTTCAACATCCGCACCGATGTCACCTACTCTGATGGCACCCCGCTGACGGCTGAAAACGTGG
TGAAAAACTTCGATCTCTATGGCCTCGGCGATCAAGATCGACGCCTCACCATCTCTGAGCAGATCACCAACTATGACTAC
GGTGAAGTAGTAGATGAGGACACCGTCCGATTCCACTTCTCTGAGCCTGCACCTGGTTTTGCTCAGGCCACCAGCTCCTT
CAACGCTGGCCTTTATGCCGATTCCACCTTGGAGTTCGCCAATGAGGATTTCGCCCCAGGCAACGCTCAAAACGTCATCG
GCTCTGGTCCTTTTGTAATCACCGATGAAACCCTAGGCACCAACCTCACCTTGACTGCGCGTGAGGATTACGATTGGGCA
CCACCATCACGCGAACATCAAGGTCGCGCGAAGCTTGACGCCGTCAATTATGTCCTCGCGGGTGAAGAATCCGTCCGCAT
CGGAGCCATCGTTGCTGGCCAAGGTGATATCGCCCGCCAGATCGAAGCGCCAGTGGAGGCACACCTGAAGGATGCAGGCA
TCCCGATCATCTCCGCAGCCACCAACGGTGTGAACAACAGCTTCAACTTCCGCTTCAAAAACGAGCTGCTCTCAGACATC
CGTGTTCGCCAAGCTCTGATCCACGCGATCGACCGCGAAAAGATCATGCGTGTGCTGTTTAGTGATTCCTATCCGCTGGC
AACTTCTGTGCTTGCGCAAAATGCACTGGGCTACAAAGAACAAGTAGATGCCTATGTCTACGACCTAGACAAAGCAACAG
CTCTGCTTGACGAAGCCGGCTGGACCCTTGATAGCGACGGCATGCGTCGCAAGGACGGTGAACTTCTAGAGCTCACCTTC
AACGAAGCCCTCCCACAGCCTCGTTCACGCGAAGTTGTCACCATGGTCCAAGAACAGCTCGGTGATCTGGGCATCAAGGT
CAACCTCAACCCAGGTGACCAAGCAGCCCAGGACGCTGACTCCAAGGATCTCAACAAGATCCAGGTTCGCCACACCATGG
TGGGTCGCGCAGACTATGACGTGCTGAAATCCCAGCTGTACTCCACCAACCGCAACGAGCTGTTGAACATGACCATGGAA
GGGGAGACCGCCGATATTGGCGATCCTCATTTGGAGGAACTCCTCATGGCTATTGCATCCAGCCCACGCGAAGAGGACCG
TGCAGCAGCATCTGCGGCAGCACAGGATTACATCACCGAGCAGGCATATGTTCTTCCACTGTTTGAAGAGCCAGTTGTCT
ACGGCGTGCAGCCTTACGTGAAGGGCTTTAGCCCCGAAGTTATCGGCCGCCCCAGCTTCTATGAGACCTACATTGACCAT
TCCAGTAACGATTCCAGTGAGGAGGACTAA

Upstream 100 bases:

>100_bases
TCTAAACCAATGTACCGCTTAGTCTGAAAGTGTGTTAAGTTCTGGGACATAAATTAGCTGACACGTAAAGTAACTTAAAT
ATTCACTGGAGGTAAGCCTA

Downstream 100 bases:

>100_bases
ATGACTACCTCGCAGATTCTGCGCCGCATCGGCCAAGCCGTCTTGGTCTTGTTGGTCACCTTTACCTTGGCGTTCATCAT
GCTTTCCGCCCTCCCTGGCG

Product: hypothetical protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MFKKHRHGLGSPETKPHLKTRRFFTAAAATLAGLAVLSGCTAQPSQAEDNTLTYLEPQFFRTLYPPSAGFYPNGSVVNNI
ADRLLYQDPETLELKPWIATELPEINEDATEFTFNIRTDVTYSDGTPLTAENVVKNFDLYGLGDQDRRLTISEQITNYDY
GEVVDEDTVRFHFSEPAPGFAQATSSFNAGLYADSTLEFANEDFAPGNAQNVIGSGPFVITDETLGTNLTLTAREDYDWA
PPSREHQGRAKLDAVNYVLAGEESVRIGAIVAGQGDIARQIEAPVEAHLKDAGIPIISAATNGVNNSFNFRFKNELLSDI
RVRQALIHAIDREKIMRVLFSDSYPLATSVLAQNALGYKEQVDAYVYDLDKATALLDEAGWTLDSDGMRRKDGELLELTF
NEALPQPRSREVVTMVQEQLGDLGIKVNLNPGDQAAQDADSKDLNKIQVRHTMVGRADYDVLKSQLYSTNRNELLNMTME
GETADIGDPHLEELLMAIASSPREEDRAAASAAAQDYITEQAYVLPLFEEPVVYGVQPYVKGFSPEVIGRPSFYETYIDH
SSNDSSEED

Sequences:

>Translated_569_residues
MFKKHRHGLGSPETKPHLKTRRFFTAAAATLAGLAVLSGCTAQPSQAEDNTLTYLEPQFFRTLYPPSAGFYPNGSVVNNI
ADRLLYQDPETLELKPWIATELPEINEDATEFTFNIRTDVTYSDGTPLTAENVVKNFDLYGLGDQDRRLTISEQITNYDY
GEVVDEDTVRFHFSEPAPGFAQATSSFNAGLYADSTLEFANEDFAPGNAQNVIGSGPFVITDETLGTNLTLTAREDYDWA
PPSREHQGRAKLDAVNYVLAGEESVRIGAIVAGQGDIARQIEAPVEAHLKDAGIPIISAATNGVNNSFNFRFKNELLSDI
RVRQALIHAIDREKIMRVLFSDSYPLATSVLAQNALGYKEQVDAYVYDLDKATALLDEAGWTLDSDGMRRKDGELLELTF
NEALPQPRSREVVTMVQEQLGDLGIKVNLNPGDQAAQDADSKDLNKIQVRHTMVGRADYDVLKSQLYSTNRNELLNMTME
GETADIGDPHLEELLMAIASSPREEDRAAASAAAQDYITEQAYVLPLFEEPVVYGVQPYVKGFSPEVIGRPSFYETYIDH
SSNDSSEED
>Mature_569_residues
MFKKHRHGLGSPETKPHLKTRRFFTAAAATLAGLAVLSGCTAQPSQAEDNTLTYLEPQFFRTLYPPSAGFYPNGSVVNNI
ADRLLYQDPETLELKPWIATELPEINEDATEFTFNIRTDVTYSDGTPLTAENVVKNFDLYGLGDQDRRLTISEQITNYDY
GEVVDEDTVRFHFSEPAPGFAQATSSFNAGLYADSTLEFANEDFAPGNAQNVIGSGPFVITDETLGTNLTLTAREDYDWA
PPSREHQGRAKLDAVNYVLAGEESVRIGAIVAGQGDIARQIEAPVEAHLKDAGIPIISAATNGVNNSFNFRFKNELLSDI
RVRQALIHAIDREKIMRVLFSDSYPLATSVLAQNALGYKEQVDAYVYDLDKATALLDEAGWTLDSDGMRRKDGELLELTF
NEALPQPRSREVVTMVQEQLGDLGIKVNLNPGDQAAQDADSKDLNKIQVRHTMVGRADYDVLKSQLYSTNRNELLNMTME
GETADIGDPHLEELLMAIASSPREEDRAAASAAAQDYITEQAYVLPLFEEPVVYGVQPYVKGFSPEVIGRPSFYETYIDH
SSNDSSEED

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=566, Percent_Identity=22.9681978798587, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1787052, Length=450, Percent_Identity=22, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787762, Length=460, Percent_Identity=23.2608695652174, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62912; Mature: 62912

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKHRHGLGSPETKPHLKTRRFFTAAAATLAGLAVLSGCTAQPSQAEDNTLTYLEPQFF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHH
RTLYPPSAGFYPNGSVVNNIADRLLYQDPETLELKPWIATELPEINEDATEFTFNIRTDV
HHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHCCCCCCCCCCEEEEEEEEEE
TYSDGTPLTAENVVKNFDLYGLGDQDRRLTISEQITNYDYGEVVDEDTVRFHFSEPAPGF
EECCCCCCCHHHHHHCCCEEECCCCCCEEEHHHHHCCCCCCCCCCCCCEEEEECCCCCCH
AQATSSFNAGLYADSTLEFANEDFAPGNAQNVIGSGPFVITDETLGTNLTLTAREDYDWA
HHHHCCCCCCEEECCHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCC
PPSREHQGRAKLDAVNYVLAGEESVRIGAIVAGQGDIARQIEAPVEAHLKDAGIPIISAA
CCCCCCCCCCHHHHEEEEEECCCCEEEEEEEECCCHHHHHHHCCHHHHHHHCCCCEEEEC
TNGVNNSFNFRFKNELLSDIRVRQALIHAIDREKIMRVLFSDSYPLATSVLAQNALGYKE
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHH
QVDAYVYDLDKATALLDEAGWTLDSDGMRRKDGELLELTFNEALPQPRSREVVTMVQEQL
HHHHHEEEHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHH
GDLGIKVNLNPGDQAAQDADSKDLNKIQVRHTMVGRADYDVLKSQLYSTNRNELLNMTME
CCCCEEEECCCCCHHHCCCCCCCCHHEEEEHHHHCCCHHHHHHHHHHCCCCCCEEEEEEC
GETADIGDPHLEELLMAIASSPREEDRAAASAAAQDYITEQAYVLPLFEEPVVYGVQPYV
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCHHH
KGFSPEVIGRPSFYETYIDHSSNDSSEED
CCCCCCCCCCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFKKHRHGLGSPETKPHLKTRRFFTAAAATLAGLAVLSGCTAQPSQAEDNTLTYLEPQFF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHH
RTLYPPSAGFYPNGSVVNNIADRLLYQDPETLELKPWIATELPEINEDATEFTFNIRTDV
HHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHCCCCCCCCCCEEEEEEEEEE
TYSDGTPLTAENVVKNFDLYGLGDQDRRLTISEQITNYDYGEVVDEDTVRFHFSEPAPGF
EECCCCCCCHHHHHHCCCEEECCCCCCEEEHHHHHCCCCCCCCCCCCCEEEEECCCCCCH
AQATSSFNAGLYADSTLEFANEDFAPGNAQNVIGSGPFVITDETLGTNLTLTAREDYDWA
HHHHCCCCCCEEECCHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCC
PPSREHQGRAKLDAVNYVLAGEESVRIGAIVAGQGDIARQIEAPVEAHLKDAGIPIISAA
CCCCCCCCCCHHHHEEEEEECCCCEEEEEEEECCCHHHHHHHCCHHHHHHHCCCCEEEEC
TNGVNNSFNFRFKNELLSDIRVRQALIHAIDREKIMRVLFSDSYPLATSVLAQNALGYKE
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHH
QVDAYVYDLDKATALLDEAGWTLDSDGMRRKDGELLELTFNEALPQPRSREVVTMVQEQL
HHHHHEEEHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHH
GDLGIKVNLNPGDQAAQDADSKDLNKIQVRHTMVGRADYDVLKSQLYSTNRNELLNMTME
CCCCEEEECCCCCHHHCCCCCCCCHHEEEEHHHHCCCHHHHHHHHHHCCCCCCEEEEEEC
GETADIGDPHLEELLMAIASSPREEDRAAASAAAQDYITEQAYVLPLFEEPVVYGVQPYV
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCHHH
KGFSPEVIGRPSFYETYIDHSSNDSSEED
CCCCCCCCCCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]