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The map label for this gene is ybeX [C]

Identifier: 145296241

GI number: 145296241

Start: 2380638

End: 2381960

Strand: Reverse

Name: ybeX [C]

Synonym: cgR_2158

Alternate gene names: 145296241

Gene position: 2381960-2380638 (Counterclockwise)

Preceding gene: 145296242

Following gene: 145296240

Centisome position: 71.87

GC content: 55.71

Gene sequence:

>1323_bases
GTGGAATCCTCAGTTATATGGTTGAGCATCGCCACTGTCGTTGCGCTGCTCTTCTCCGGTCTATTAGGTGCAGTTGAATC
TGCGCTTTCTTCTGTTTCCCGCGCCCGCATTGAACAAATGCTCAAGGATGAAGCCTCCGGGTCCGCGTCCTTGCTGCGAG
TCATCGACGAACGCGCACTCCACATCAACATGCTCATCATGTTGCGCACCTTGCTGGATGCCTCCGCAGCAGTCTTTGCC
GGGGCAATCGCAGTCAATGTGATGGACAGCTGGGCGTGGGGAATCGTCTTGGCCATCGTGGTGGTTTCCCTCCTGACCTT
CGCAGTAGTGGGCGTGTTTGGCCGCACCGTTGGCCGCAAAAACCCATATTCAGTGATGCTTCGCTCCGCAGTCGTGCTGA
GCGGTTTAGCTAAAATCCTTGGCCCCATTGCACGTGGCCTCATCTGGATCGGCAACATCATCGCGCCCGGCCCAGGTTTC
CGCAATGGCCCTTACGCCACTGAAGTGGAGCTGCGTGAGATGGTCGATATCGCCCAAGAACACGGCATCGTGGAAATTGA
AGAGCGCCGCATGATCCAGTCGGTGTTCGACCTGGCATCCACGACGGTTCGCCAGGTGATGGTGCCGCGTCCTGAAATGA
TCTGGATTGAATCTGGAAAAACAGCCGGGCAAGCAACCGCGCTGTGCGTGCGCTCTGGTCATTCGCGCATCCCAGTCATC
GGTGAAAACGTCGATGACATCATCGGCATCGTCTACCTCAAAGACTTGGTCCAAAAAACCTACTACGCCACTGATGGCGG
AAAGTCTGTGCTTGTAGACGAGGTCATGCGCGAAGCTACCTTCGTGCCAGACTCCAAGTCCCTTGATGCGCTGCTGCAGG
AAATGCAGGAAGACCACAAACACATCGCAATCCTGGTTGATGAATACGGCGGCGTGGCAGGTCTTATTTCCATTGAGGAT
ATTTTGGAAGAAATCGTCGGTGAAATCGCTGATGAATACGACGCCCGCGAAGTAGCCCCCATCGAGAAAATCGGCGACCG
CACCTACCGCGTGGTCTCCCGACTCTCGCTGGAAGATCTCAAAGACCACATCGAAGAAGAACTCGACCTAGAAATCGAAT
TCGGTGATGAAATTGAAGATCAGGTCGACACTGTCGGTGGCCTTATTGCCTTTGAACTTGGCCGAGTGCCTCTGCCGGGT
GCCACGGTGGAAACCTGCGGACTAAAGCTCACCGCCGAGGGAGCCAAGAACCGCCGGGGTCGTTTGCGCATGCATTCAGC
AGTCGTCGAAGTTGCCGAGCCCAGCGAGGACAACGAAGGTTAG

Upstream 100 bases:

>100_bases
ACCATCCGGCGCCGGTGCATTCCCCACCGCTGCTGATCGTCTGGAATTGGACGAGAAGATGGAAGCGGATGACTCTGGCT
TTGGAGGCGTTGAGTCCTAG

Downstream 100 bases:

>100_bases
TTTTTTACAGCAGTAGGGGACTATGCTGGGACGTCCAAGGAAACCGTCCCTTTTTTGCCAAGAAGTGGCTGGTTCGATCA
TCCCAAACTTTCAAAGAGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MESSVIWLSIATVVALLFSGLLGAVESALSSVSRARIEQMLKDEASGSASLLRVIDERALHINMLIMLRTLLDASAAVFA
GAIAVNVMDSWAWGIVLAIVVVSLLTFAVVGVFGRTVGRKNPYSVMLRSAVVLSGLAKILGPIARGLIWIGNIIAPGPGF
RNGPYATEVELREMVDIAQEHGIVEIEERRMIQSVFDLASTTVRQVMVPRPEMIWIESGKTAGQATALCVRSGHSRIPVI
GENVDDIIGIVYLKDLVQKTYYATDGGKSVLVDEVMREATFVPDSKSLDALLQEMQEDHKHIAILVDEYGGVAGLISIED
ILEEIVGEIADEYDAREVAPIEKIGDRTYRVVSRLSLEDLKDHIEEELDLEIEFGDEIEDQVDTVGGLIAFELGRVPLPG
ATVETCGLKLTAEGAKNRRGRLRMHSAVVEVAEPSEDNEG

Sequences:

>Translated_440_residues
MESSVIWLSIATVVALLFSGLLGAVESALSSVSRARIEQMLKDEASGSASLLRVIDERALHINMLIMLRTLLDASAAVFA
GAIAVNVMDSWAWGIVLAIVVVSLLTFAVVGVFGRTVGRKNPYSVMLRSAVVLSGLAKILGPIARGLIWIGNIIAPGPGF
RNGPYATEVELREMVDIAQEHGIVEIEERRMIQSVFDLASTTVRQVMVPRPEMIWIESGKTAGQATALCVRSGHSRIPVI
GENVDDIIGIVYLKDLVQKTYYATDGGKSVLVDEVMREATFVPDSKSLDALLQEMQEDHKHIAILVDEYGGVAGLISIED
ILEEIVGEIADEYDAREVAPIEKIGDRTYRVVSRLSLEDLKDHIEEELDLEIEFGDEIEDQVDTVGGLIAFELGRVPLPG
ATVETCGLKLTAEGAKNRRGRLRMHSAVVEVAEPSEDNEG
>Mature_440_residues
MESSVIWLSIATVVALLFSGLLGAVESALSSVSRARIEQMLKDEASGSASLLRVIDERALHINMLIMLRTLLDASAAVFA
GAIAVNVMDSWAWGIVLAIVVVSLLTFAVVGVFGRTVGRKNPYSVMLRSAVVLSGLAKILGPIARGLIWIGNIIAPGPGF
RNGPYATEVELREMVDIAQEHGIVEIEERRMIQSVFDLASTTVRQVMVPRPEMIWIESGKTAGQATALCVRSGHSRIPVI
GENVDDIIGIVYLKDLVQKTYYATDGGKSVLVDEVMREATFVPDSKSLDALLQEMQEDHKHIAILVDEYGGVAGLISIED
ILEEIVGEIADEYDAREVAPIEKIGDRTYRVVSRLSLEDLKDHIEEELDLEIEFGDEIEDQVDTVGGLIAFELGRVPLPG
ATVETCGLKLTAEGAKNRRGRLRMHSAVVEVAEPSEDNEG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=309, Percent_Identity=28.8025889967638, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI94681046, Length=179, Percent_Identity=29.608938547486, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1786879, Length=259, Percent_Identity=34.3629343629344, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87082033, Length=232, Percent_Identity=29.3103448275862, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI145693175, Length=334, Percent_Identity=24.8502994011976, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788119, Length=233, Percent_Identity=31.3304721030043, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790664, Length=351, Percent_Identity=21.0826210826211, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47798; Mature: 47798

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00866 CPSASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESSVIWLSIATVVALLFSGLLGAVESALSSVSRARIEQMLKDEASGSASLLRVIDERAL
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HINMLIMLRTLLDASAAVFAGAIAVNVMDSWAWGIVLAIVVVSLLTFAVVGVFGRTVGRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPYSVMLRSAVVLSGLAKILGPIARGLIWIGNIIAPGPGFRNGPYATEVELREMVDIAQE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HGIVEIEERRMIQSVFDLASTTVRQVMVPRPEMIWIESGKTAGQATALCVRSGHSRIPVI
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCEE
GENVDDIIGIVYLKDLVQKTYYATDGGKSVLVDEVMREATFVPDSKSLDALLQEMQEDHK
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
HIAILVDEYGGVAGLISIEDILEEIVGEIADEYDAREVAPIEKIGDRTYRVVSRLSLEDL
EEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHH
KDHIEEELDLEIEFGDEIEDQVDTVGGLIAFELGRVPLPGATVETCGLKLTAEGAKNRRG
HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEECCCCCCCC
RLRMHSAVVEVAEPSEDNEG
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MESSVIWLSIATVVALLFSGLLGAVESALSSVSRARIEQMLKDEASGSASLLRVIDERAL
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HINMLIMLRTLLDASAAVFAGAIAVNVMDSWAWGIVLAIVVVSLLTFAVVGVFGRTVGRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPYSVMLRSAVVLSGLAKILGPIARGLIWIGNIIAPGPGFRNGPYATEVELREMVDIAQE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HGIVEIEERRMIQSVFDLASTTVRQVMVPRPEMIWIESGKTAGQATALCVRSGHSRIPVI
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCEE
GENVDDIIGIVYLKDLVQKTYYATDGGKSVLVDEVMREATFVPDSKSLDALLQEMQEDHK
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
HIAILVDEYGGVAGLISIEDILEEIVGEIADEYDAREVAPIEKIGDRTYRVVSRLSLEDL
EEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHH
KDHIEEELDLEIEFGDEIEDQVDTVGGLIAFELGRVPLPGATVETCGLKLTAEGAKNRRG
HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEECCCCCCCC
RLRMHSAVVEVAEPSEDNEG
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]