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The map label for this gene is dtd

Identifier: 145295823

GI number: 145295823

Start: 1939397

End: 1939831

Strand: Direct

Name: dtd

Synonym: cgR_1748

Alternate gene names: 145295823

Gene position: 1939397-1939831 (Clockwise)

Preceding gene: 145295822

Following gene: 145295824

Centisome position: 58.52

GC content: 55.4

Gene sequence:

>435_bases
GTGAAAGCCGTTTTAACCCGTGTGAGTTCCGCCAGCGTCAGCGTGGATGATGAAATTGTTGGAGCCATCGATTGCCCCGA
CACCGGAGGCATTTTGGCGCTGGTTGGAGTCGGCGCTGCTGATAGCGACGACGCCTGGGAAACCATGGTGCGAAAAATTG
CTGAGCTGCGCATCTTGGATGGCGAACAATCCGTCAGTGATGTCAATGCTCCCGTACTGCTTGTTAGCCAATTCACCCTG
CATGGTCGCACCGCAAAAGGCCGGCGCCCATCGTGGTCTGATGCAGCACCTGGTGAGGTGGCTGAGCCGGTGATTGAAAA
GATTGCACAAGGTTTACGTGAGCGCGGAATCACCGTGGAACAAGGACGATTCGGCGCAATGATGAAGGTCACATCGGTTA
ACGAAGGCCCCTTCACCGTTTTGGTCGAGTGCTAA

Upstream 100 bases:

>100_bases
GAATCCCTGCACAACGGCGCCATTGCGGCGTTGGTGGATCTCATCCGCCACGGATTAGTGTTGCCCGCTGATCTTCTCGA
TTCTTAAATAAGGACTGTTT

Downstream 100 bases:

>100_bases
CCAGTCAAGCCTAAGAGCTTGAAACGCCCCAATGTGGGGGTGTTAAGAACTCCACAAAAGCGCTTGGGAACTTTTTGTGG
AAGCAGTCCGTTGAACCTCT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKAVLTRVSSASVSVDDEIVGAIDCPDTGGILALVGVGAADSDDAWETMVRKIAELRILDGEQSVSDVNAPVLLVSQFTL
HGRTAKGRRPSWSDAAPGEVAEPVIEKIAQGLRERGITVEQGRFGAMMKVTSVNEGPFTVLVEC

Sequences:

>Translated_144_residues
MKAVLTRVSSASVSVDDEIVGAIDCPDTGGILALVGVGAADSDDAWETMVRKIAELRILDGEQSVSDVNAPVLLVSQFTL
HGRTAKGRRPSWSDAAPGEVAEPVIEKIAQGLRERGITVEQGRFGAMMKVTSVNEGPFTVLVEC
>Mature_144_residues
MKAVLTRVSSASVSVDDEIVGAIDCPDTGGILALVGVGAADSDDAWETMVRKIAELRILDGEQSVSDVNAPVLLVSQFTL
HGRTAKGRRPSWSDAAPGEVAEPVIEKIAQGLRERGITVEQGRFGAMMKVTSVNEGPFTVLVEC

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=151, Percent_Identity=39.0728476821192, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1790320, Length=148, Percent_Identity=33.1081081081081, Blast_Score=81, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=38, Blast_Score=82, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319982, Length=154, Percent_Identity=35.0649350649351, Blast_Score=91, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281361569, Length=150, Percent_Identity=38, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_CORGB (A4QES6)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138644.1
- ProteinModelPortal:   A4QES6
- SMR:   A4QES6
- STRING:   A4QES6
- GeneID:   4993745
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1748
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15193; Mature: 15193

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: ACT_SITE 79-79

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLTRVSSASVSVDDEIVGAIDCPDTGGILALVGVGAADSDDAWETMVRKIAELRILD
CCHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEC
GEQSVSDVNAPVLLVSQFTLHGRTAKGRRPSWSDAAPGEVAEPVIEKIAQGLRERGITVE
CCCCHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
QGRFGAMMKVTSVNEGPFTVLVEC
CCCCCEEEEEEECCCCCEEEEEEC
>Mature Secondary Structure
MKAVLTRVSSASVSVDDEIVGAIDCPDTGGILALVGVGAADSDDAWETMVRKIAELRILD
CCHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEC
GEQSVSDVNAPVLLVSQFTLHGRTAKGRRPSWSDAAPGEVAEPVIEKIAQGLRERGITVE
CCCCHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
QGRFGAMMKVTSVNEGPFTVLVEC
CCCCCEEEEEEECCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA