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The map label for this gene is ruvA

Identifier: 145295781

GI number: 145295781

Start: 1900921

End: 1901541

Strand: Reverse

Name: ruvA

Synonym: cgR_1706

Alternate gene names: 145295781

Gene position: 1901541-1900921 (Counterclockwise)

Preceding gene: 145295782

Following gene: 145295780

Centisome position: 57.38

GC content: 53.78

Gene sequence:

>621_bases
ATGATTGCCTCACTTCGTGGCACTGTTATCAACATTGGTCTGAGCTCTGCTGTCATTGAATGCAATGGCGTGGGCTATGA
GGTTGTCACCACACCGAACACCTTGTCACAGTTGGTCCGCGGTGAGGAAGCGTTGGTGTTGACCACCATGGTGGTCCGCG
AAGACGCGATGAAACTCTATGGGTTTATTGATAATGAATCACGTGAGATGTTTTCCGTGTTGCAAACAGTATCTGGGTTG
GGTCCACGCCTGGCCTTGGCATGTGAATCGGTGTTGAGCCCACTGGAGATTTCTCAGGCGATCACCAATGCTGATGCCAA
AGCTTTGCAGCGGGTTCCGGGTGTGGGAAAGCGCATGGCAGATCGTCTCATCGTGGAGCTTAAAGGCAAGGTCGCAGCTT
TTGCTGCCGGTGTCGTGGATGAGGCAGGGGAGCAGATTTCCTTGCCTAACGCGAACATTGCTTCTGAGGTGGTTGTGGAG
CAGGTTTCTCAAGCGCTGGTGGGCTTGGGCTTTAGCGAGAAGCAATCAGATGATGCAGTGAGCTTTGTGCTGGCGGCGGA
TCCATCCTTGGACACCAGTGGCGCGCTTCGTGCCGCATTGGCAAAACTCAGCGGAAAGTAG

Upstream 100 bases:

>100_bases
TGCATCCGATCCTGCTAAAGTCGCTCATCCCAGTCAGTTTCAACGAACTGACACCAATTAGTTTTTAAAAAGTTCTAGTA
GATTTTTCAGGAGTGTCTTC

Downstream 100 bases:

>100_bases
ACCCTCATGTCCGATGTGGAAAGAACAGAGTTTGAAATTCCGGGAGGAATTCCACCTCGTCGAAACGGTGGTCAAGGCCG
TGCAGCTGATACCAACGTAG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIASLRGTVINIGLSSAVIECNGVGYEVVTTPNTLSQLVRGEEALVLTTMVVREDAMKLYGFIDNESREMFSVLQTVSGL
GPRLALACESVLSPLEISQAITNADAKALQRVPGVGKRMADRLIVELKGKVAAFAAGVVDEAGEQISLPNANIASEVVVE
QVSQALVGLGFSEKQSDDAVSFVLAADPSLDTSGALRAALAKLSGK

Sequences:

>Translated_206_residues
MIASLRGTVINIGLSSAVIECNGVGYEVVTTPNTLSQLVRGEEALVLTTMVVREDAMKLYGFIDNESREMFSVLQTVSGL
GPRLALACESVLSPLEISQAITNADAKALQRVPGVGKRMADRLIVELKGKVAAFAAGVVDEAGEQISLPNANIASEVVVE
QVSQALVGLGFSEKQSDDAVSFVLAADPSLDTSGALRAALAKLSGK
>Mature_206_residues
MIASLRGTVINIGLSSAVIECNGVGYEVVTTPNTLSQLVRGEEALVLTTMVVREDAMKLYGFIDNESREMFSVLQTVSGL
GPRLALACESVLSPLEISQAITNADAKALQRVPGVGKRMADRLIVELKGKVAAFAAGVVDEAGEQISLPNANIASEVVVE
QVSQALVGLGFSEKQSDDAVSFVLAADPSLDTSGALRAALAKLSGK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=36.9458128078818, Blast_Score=118, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_CORGB (A4QEN4)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138602.1
- ProteinModelPortal:   A4QEN4
- SMR:   A4QEN4
- STRING:   A4QEN4
- GeneID:   4994519
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1706
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21461; Mature: 21461

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASLRGTVINIGLSSAVIECNGVGYEVVTTPNTLSQLVRGEEALVLTTMVVREDAMKLY
CCCCCCCEEEEECCCCEEEEECCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GFIDNESREMFSVLQTVSGLGPRLALACESVLSPLEISQAITNADAKALQRVPGVGKRMA
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHCCCCHHHHH
DRLIVELKGKVAAFAAGVVDEAGEQISLPNANIASEVVVEQVSQALVGLGFSEKQSDDAV
HHHHHHHCCHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE
SFVLAADPSLDTSGALRAALAKLSGK
EEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIASLRGTVINIGLSSAVIECNGVGYEVVTTPNTLSQLVRGEEALVLTTMVVREDAMKLY
CCCCCCCEEEEECCCCEEEEECCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GFIDNESREMFSVLQTVSGLGPRLALACESVLSPLEISQAITNADAKALQRVPGVGKRMA
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHCCCCHHHHH
DRLIVELKGKVAAFAAGVVDEAGEQISLPNANIASEVVVEQVSQALVGLGFSEKQSDDAV
HHHHHHHCCHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE
SFVLAADPSLDTSGALRAALAKLSGK
EEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA