Click here to switch to the map view.

The map label for this gene is ruvB

Identifier: 145295780

GI number: 145295780

Start: 1899823

End: 1900914

Strand: Reverse

Name: ruvB

Synonym: cgR_1705

Alternate gene names: 145295780

Gene position: 1900914-1899823 (Counterclockwise)

Preceding gene: 145295781

Following gene: 145295779

Centisome position: 57.36

GC content: 55.95

Gene sequence:

>1092_bases
ATGTCCGATGTGGAAAGAACAGAGTTTGAAATTCCGGGAGGAATTCCACCTCGTCGAAACGGTGGTCAAGGCCGTGCAGC
TGATACCAACGTAGATGCGAACCTGAAGCCTGATGAATACGATGCGGAAGTAACACTTCGTCCGAAGTCTTTGACCGAGT
TTATCGGCCAACCGAAGGTGCGCGATCAGCTTAGTTTGGTGCTTACCGGCGCGAAAAACCGTGGTGTGGTTCCCGATCAC
GTGTTGTTGTCTGGCCCTCCTGGCCTGGGTAAGACCACCATGGCGATGATTATCGCCCAGGAGTTGGGCACCAGTTTGCG
TATGACCTCAGGCCCAGCCTTGGAACGCGCAGGCGATCTGGCTGCCATGCTGTCCAACCTCATGGAAGGGGACGTGCTGT
TTATTGATGAGATTCACCGCATCGCACGTCCTGCCGAGGAAATGCTGTACATGGCGATGGAAGATTTCCGGATCGATGTC
ATCGTCGGTAAAGGTCCTGGCGCTACCTCAATCCCGCTGGAGATCCCACCCTTTACCCTCGTTGGTGCAACCACCAGGTC
GGGTATGCTCACCGGCCCACTGCGTGACCGTTTCGGTTTTACCGCGCAGATGGAATTCTACGATGTGCCTGATCTGACCA
AAGTGGTGAAACGAACAGCTAAGATCCTCGATGTCGGAATCGACAACGATGCTGCTGTGGAAATCGCCTCGCGGTCTCGT
GGTACTCCTCGTATTGCTAACCGACTGCTTCGTCGAGTCCGTGACTTCGCTGAAGTTCATGCGGATGGTCACATCACGAT
GGGGGCAGCCAATGCTGCGCTGATTGTATTCGATGTCGATGAAGTCGGACTCGATCGCCTGGATAGGGCAGTGCTTGATG
CCTTGATCCGCGGACATGGCGGAGGCCCTGTTGGCGTGAACACACTCGCGGTTGCAGTTGGTGAAGAACCCGGCACTGTG
GAAGAAGTATGCGAGCCCTATTTGGTGCGTGCCGGCATGATTGCACGAACCGGACGGGGACGCGTGGCAACCGCAGCTGC
ATGGAGACACCTGGGGCTGGAACCACCAGAAGGCACCATCGGCGATTATTAG

Upstream 100 bases:

>100_bases
AGATGATGCAGTGAGCTTTGTGCTGGCGGCGGATCCATCCTTGGACACCAGTGGCGCGCTTCGTGCCGCATTGGCAAAAC
TCAGCGGAAAGTAGACCCTC

Downstream 100 bases:

>100_bases
CCACCTTAGGTGGCCAGGATGTTCCATGGTCTGGCAAACTAGCTAACCATGGACATCCTTTTCCTCATAGTTCTTCTAGC
CATTTTTATCGTTCCCACCT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSDVERTEFEIPGGIPPRRNGGQGRAADTNVDANLKPDEYDAEVTLRPKSLTEFIGQPKVRDQLSLVLTGAKNRGVVPDH
VLLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDLAAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDV
IVGKGPGATSIPLEIPPFTLVGATTRSGMLTGPLRDRFGFTAQMEFYDVPDLTKVVKRTAKILDVGIDNDAAVEIASRSR
GTPRIANRLLRRVRDFAEVHADGHITMGAANAALIVFDVDEVGLDRLDRAVLDALIRGHGGGPVGVNTLAVAVGEEPGTV
EEVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTIGDY

Sequences:

>Translated_363_residues
MSDVERTEFEIPGGIPPRRNGGQGRAADTNVDANLKPDEYDAEVTLRPKSLTEFIGQPKVRDQLSLVLTGAKNRGVVPDH
VLLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDLAAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDV
IVGKGPGATSIPLEIPPFTLVGATTRSGMLTGPLRDRFGFTAQMEFYDVPDLTKVVKRTAKILDVGIDNDAAVEIASRSR
GTPRIANRLLRRVRDFAEVHADGHITMGAANAALIVFDVDEVGLDRLDRAVLDALIRGHGGGPVGVNTLAVAVGEEPGTV
EEVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTIGDY
>Mature_362_residues
SDVERTEFEIPGGIPPRRNGGQGRAADTNVDANLKPDEYDAEVTLRPKSLTEFIGQPKVRDQLSLVLTGAKNRGVVPDHV
LLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDLAAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDVI
VGKGPGATSIPLEIPPFTLVGATTRSGMLTGPLRDRFGFTAQMEFYDVPDLTKVVKRTAKILDVGIDNDAAVEIASRSRG
TPRIANRLLRRVRDFAEVHADGHITMGAANAALIVFDVDEVGLDRLDRAVLDALIRGHGGGPVGVNTLAVAVGEEPGTVE
EVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTIGDY

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=331, Percent_Identity=55.2870090634441, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_CORGB (A4QEN3)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138601.1
- ProteinModelPortal:   A4QEN3
- SMR:   A4QEN3
- STRING:   A4QEN3
- GeneID:   4993889
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1705
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38905; Mature: 38774

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVERTEFEIPGGIPPRRNGGQGRAADTNVDANLKPDEYDAEVTLRPKSLTEFIGQPKV
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCCH
RDQLSLVLTGAKNRGVVPDHVLLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDL
HCCEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHH
AAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDVIVGKGPGATSIPLEIPPFTL
HHHHHHHHCCCEEEHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEECCCEEE
VGATTRSGMLTGPLRDRFGFTAQMEFYDVPDLTKVVKRTAKILDVGIDNDAAVEIASRSR
EECCCCCCEEECCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHEECCCCCCEEEECCCCC
GTPRIANRLLRRVRDFAEVHADGHITMGAANAALIVFDVDEVGLDRLDRAVLDALIRGHG
CCHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEECCHHCHHHHHHHHHHHHHHCCC
GGPVGVNTLAVAVGEEPGTVEEVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTI
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCC
GDY
CCC
>Mature Secondary Structure 
SDVERTEFEIPGGIPPRRNGGQGRAADTNVDANLKPDEYDAEVTLRPKSLTEFIGQPKV
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCCH
RDQLSLVLTGAKNRGVVPDHVLLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDL
HCCEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHH
AAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDVIVGKGPGATSIPLEIPPFTL
HHHHHHHHCCCEEEHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEECCCEEE
VGATTRSGMLTGPLRDRFGFTAQMEFYDVPDLTKVVKRTAKILDVGIDNDAAVEIASRSR
EECCCCCCEEECCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHEECCCCCCEEEECCCCC
GTPRIANRLLRRVRDFAEVHADGHITMGAANAALIVFDVDEVGLDRLDRAVLDALIRGHG
CCHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEECCHHCHHHHHHHHHHHHHHCCC
GGPVGVNTLAVAVGEEPGTVEEVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTI
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCC
GDY
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA