Click here to switch to the map view.

The map label for this gene is pyrR

Identifier: 145295735

GI number: 145295735

Start: 1849510

End: 1850088

Strand: Reverse

Name: pyrR

Synonym: cgR_1662

Alternate gene names: 145295735

Gene position: 1850088-1849510 (Counterclockwise)

Preceding gene: 145295740

Following gene: 145295734

Centisome position: 55.82

GC content: 54.4

Gene sequence:

>579_bases
ATGAGCGAACGTAATAGTGCTGTACTAGAACTCCTCAATGAGGACGACGTCAGCCGTACCATCGCACGCATCGCGCACCA
GATTATTGAGAAAACCGCGCTTGATTCCAAAGACGCGGATCGGGTCATGTTGTTAGGCATTCCTTCAGGTGGAGTCCCGC
TGGCCCGAAGGCTTGCTGAAAAGATCGAAGAATTTTCCGGCGTTTCGGTAGATACCGGCGCTGTTGATATCACCTTGTAC
AGGGATGATCTTCGAAACAAACCGCACCGCGCACTGCAGCCCACCTCTATTCCGGCAGGTGGTATCGATAACACCACCGT
GATTTTGGTGGATGATGTGCTGTTTTCCGGTCGTACTATCCGCGCTGCACTTGATGCATTGCGCGACGTTGGACGCCCAA
ACTATATCCAATTAGCTGTGTTGGTTGACCGCGGTCACCGCCAGCTGCCCATTCGCGCTGACTATGTGGGCAAAAATCTC
CCCACCGCACGCGCGGAAGATGTTTCCGTCATGCTTGCGGAAATCGACGGCCGCGACGCAGTCACGCTCACCCGAGAAGA
CTCTGAAGGGGATTCCTAG

Upstream 100 bases:

>100_bases
ATAGTGTCAGACAACAACCAGGAAACTGGTCGTTGCAGAGTTTTTGCAAAATTGGACATCCTTTAACGGACCGCACAGAG
AGGCGGGGAAGGAGGTCACG

Downstream 100 bases:

>100_bases
ATGAAGCACCTCCTATCCATTAGCGATCTTTCCAAAGATGAGATTGTTGGATTGCTGGATGAAGCGGATCGCTTTAAGGA
GGTGCTCGAAGGACGTGAAG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MSERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADRVMLLGIPSGGVPLARRLAEKIEEFSGVSVDTGAVDITLY
RDDLRNKPHRALQPTSIPAGGIDNTTVILVDDVLFSGRTIRAALDALRDVGRPNYIQLAVLVDRGHRQLPIRADYVGKNL
PTARAEDVSVMLAEIDGRDAVTLTREDSEGDS

Sequences:

>Translated_192_residues
MSERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADRVMLLGIPSGGVPLARRLAEKIEEFSGVSVDTGAVDITLY
RDDLRNKPHRALQPTSIPAGGIDNTTVILVDDVLFSGRTIRAALDALRDVGRPNYIQLAVLVDRGHRQLPIRADYVGKNL
PTARAEDVSVMLAEIDGRDAVTLTREDSEGDS
>Mature_191_residues
SERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADRVMLLGIPSGGVPLARRLAEKIEEFSGVSVDTGAVDITLYR
DDLRNKPHRALQPTSIPAGGIDNTTVILVDDVLFSGRTIRAALDALRDVGRPNYIQLAVLVDRGHRQLPIRADYVGKNLP
TARAEDVSVMLAEIDGRDAVTLTREDSEGDS

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_CORGB (A4QEI8)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138556.1
- ProteinModelPortal:   A4QEI8
- SMR:   A4QEI8
- STRING:   A4QEI8
- GeneID:   4993268
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1662
- eggNOG:   COG2065
- HOGENOM:   HBG641958
- OMA:   ILDITLY
- ProtClustDB:   PRK05205
- GO:   GO:0006350
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 20922; Mature: 20791

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADRVMLLGIPSGGVPLARRLAE
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHH
KIEEFSGVSVDTGAVDITLYRDDLRNKPHRALQPTSIPAGGIDNTTVILVDDVLFSGRTI
HHHHHCCCCEECCEEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHCCCHH
RAALDALRDVGRPNYIQLAVLVDRGHRQLPIRADYVGKNLPTARAEDVSVMLAEIDGRDA
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCCCCCCCEEEEEEECCCCCE
VTLTREDSEGDS
EEEEECCCCCCC
>Mature Secondary Structure 
SERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADRVMLLGIPSGGVPLARRLAE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHH
KIEEFSGVSVDTGAVDITLYRDDLRNKPHRALQPTSIPAGGIDNTTVILVDDVLFSGRTI
HHHHHCCCCEECCEEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHCCCHH
RAALDALRDVGRPNYIQLAVLVDRGHRQLPIRADYVGKNLPTARAEDVSVMLAEIDGRDA
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCCCCCCCEEEEEEECCCCCE
VTLTREDSEGDS
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA