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The map label for this gene is soxA [H]

Identifier: 145295702

GI number: 145295702

Start: 1811175

End: 1812317

Strand: Reverse

Name: soxA [H]

Synonym: cgR_1629

Alternate gene names: 145295702

Gene position: 1812317-1811175 (Counterclockwise)

Preceding gene: 145295703

Following gene: 145295696

Centisome position: 54.68

GC content: 53.89

Gene sequence:

>1143_bases
ATGAAAATTGCGGTAATCGGCCTTGGATCAACCGGCTCCATGGCACTGTGGCACTTAAGCAACATCCCCGGTGTGGAAGC
CATCGGCTTTGAACAATTCGGAATCTCCCACGGCTACGGAGCCTTCACAGGGGAGTCCCGACTGTTTCGCATGGCTTACC
ACGAAGGCAGCACCTACGTTCCTTTGCTCAAACGCGCACAAGCACTCTGGTCATCACTAAGTGAGATTTCTGGACGCGAA
CTCTTCCACAACTTTGGTGTCTTAAGCACCGGCAAGGAAGACGAAGCACCTTTCCAACGCTTGGTGGAATCAGTGGAACG
TTATGAGCTGCCACATGAGCGACTTACCGCCGCAGAGATGCGCAAGCGTTACCCAGGCCTAGATTTCCGCGATGAAGAGG
CCGGGATTGTTGATCTTCAAGGCGGAGCGTTGCGTCCTGAGCTGGCAGTGTTCAGTGCAATCGAAGCAGCCAAGGCAAAT
GGTGCCCAAGTACGCGATCACCAAAAGATCACCAGCATTGAAGACAAAGGCGATCACGTGGTTATCCAAGCAGGTGAAGA
AACCACAATCGTGGACCGCGTTATCGTCACCACCGGCAGTTGGACAAGTGAGCTCGTGCCCTCCATCGCGCCACTGCTTG
AAGTGCGACGCCTCGTGCTCACCTGGTTCCTGCCCACCAATCCAGTAGATTTCCAGCCAGAAAATCTCCCATGCTTCATC
CGTGACCGCGATGGCTTCCATGTATTTGGAGCACCATGCGTTGATGGATACAGCATCAAAATTGCTGGATTGGATGAGTG
GGGCGTTCCATTAAGCGCTCATGTGGAAGATGAAGATCTCCGCCTTGACCGGGATGCAGTCTCTGAATTTGGTCGGAAAA
CCCACGAACTCTTCCCAGGGGTCAACCCAGAGCCCAACCGTTTCAGCGTCCACTATGACACCTACACTGCAGACAAATCT
CCAATTATCGACGCGGTGGACAATGTCATTGTGCTCACCGGAGGATCCGGACACGCCTTCAAGCTCTCTCCAGCTTATGG
CGAACTCGCAGCACAACTAGCGGTCGGAAACACCTCGCCGCTGTACAGCGAAGACTTTCGGATCGCCTCGCATGAACCAA
TCAAAGAGGCGGTGCACGTATAG

Upstream 100 bases:

>100_bases
CCTGGGCAACCCAAGTGTATGAAAACGCCCTGGAAAAAGGCATCGGCACCACATTGAACCTGTGGGAATCACCCGCACTG
GCTTGAGAGAAGAAACAACA

Downstream 100 bases:

>100_bases
AAAGCTAACCTTTTTAAGTGCGCGGTTTTAGGGTGAGAATCTAACGCTGAGCCAAAAATCCGGGTGCGAACCTCCATCGA
TTCAGATGAAGGTTCGCACC

Product: hypothetical protein

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKIAVIGLGSTGSMALWHLSNIPGVEAIGFEQFGISHGYGAFTGESRLFRMAYHEGSTYVPLLKRAQALWSSLSEISGRE
LFHNFGVLSTGKEDEAPFQRLVESVERYELPHERLTAAEMRKRYPGLDFRDEEAGIVDLQGGALRPELAVFSAIEAAKAN
GAQVRDHQKITSIEDKGDHVVIQAGEETTIVDRVIVTTGSWTSELVPSIAPLLEVRRLVLTWFLPTNPVDFQPENLPCFI
RDRDGFHVFGAPCVDGYSIKIAGLDEWGVPLSAHVEDEDLRLDRDAVSEFGRKTHELFPGVNPEPNRFSVHYDTYTADKS
PIIDAVDNVIVLTGGSGHAFKLSPAYGELAAQLAVGNTSPLYSEDFRIASHEPIKEAVHV

Sequences:

>Translated_380_residues
MKIAVIGLGSTGSMALWHLSNIPGVEAIGFEQFGISHGYGAFTGESRLFRMAYHEGSTYVPLLKRAQALWSSLSEISGRE
LFHNFGVLSTGKEDEAPFQRLVESVERYELPHERLTAAEMRKRYPGLDFRDEEAGIVDLQGGALRPELAVFSAIEAAKAN
GAQVRDHQKITSIEDKGDHVVIQAGEETTIVDRVIVTTGSWTSELVPSIAPLLEVRRLVLTWFLPTNPVDFQPENLPCFI
RDRDGFHVFGAPCVDGYSIKIAGLDEWGVPLSAHVEDEDLRLDRDAVSEFGRKTHELFPGVNPEPNRFSVHYDTYTADKS
PIIDAVDNVIVLTGGSGHAFKLSPAYGELAAQLAVGNTSPLYSEDFRIASHEPIKEAVHV
>Mature_380_residues
MKIAVIGLGSTGSMALWHLSNIPGVEAIGFEQFGISHGYGAFTGESRLFRMAYHEGSTYVPLLKRAQALWSSLSEISGRE
LFHNFGVLSTGKEDEAPFQRLVESVERYELPHERLTAAEMRKRYPGLDFRDEEAGIVDLQGGALRPELAVFSAIEAAKAN
GAQVRDHQKITSIEDKGDHVVIQAGEETTIVDRVIVTTGSWTSELVPSIAPLLEVRRLVLTWFLPTNPVDFQPENLPCFI
RDRDGFHVFGAPCVDGYSIKIAGLDEWGVPLSAHVEDEDLRLDRDAVSEFGRKTHELFPGVNPEPNRFSVHYDTYTADKS
PIIDAVDNVIVLTGGSGHAFKLSPAYGELAAQLAVGNTSPLYSEDFRIASHEPIKEAVHV

Specific function: Catalyzes the oxidative demethylation of sarcosine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI60499001, Length=385, Percent_Identity=25.1948051948052, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1787298, Length=376, Percent_Identity=28.7234042553192, Blast_Score=132, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI25147318, Length=385, Percent_Identity=24.1558441558442, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI115535191, Length=373, Percent_Identity=23.0563002680965, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002204
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 41824; Mature: 41824

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVIGLGSTGSMALWHLSNIPGVEAIGFEQFGISHGYGAFTGESRLFRMAYHEGSTYV
CEEEEEEECCCCCEEEEEECCCCCCEEECHHHCCCCCCCCCCCCCCCEEEEEECCCCEEH
PLLKRAQALWSSLSEISGRELFHNFGVLSTGKEDEAPFQRLVESVERYELPHERLTAAEM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
RKRYPGLDFRDEEAGIVDLQGGALRPELAVFSAIEAAKANGAQVRDHQKITSIEDKGDHV
HHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCEE
VIQAGEETTIVDRVIVTTGSWTSELVPSIAPLLEVRRLVLTWFLPTNPVDFQPENLPCFI
EEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCEEE
RDRDGFHVFGAPCVDGYSIKIAGLDEWGVPLSAHVEDEDLRLDRDAVSEFGRKTHELFPG
ECCCCCEEECCCCCCCEEEEEEECCCCCCCEEEECCHHHHCCCHHHHHHHHHHHHHHCCC
VNPEPNRFSVHYDTYTADKSPIIDAVDNVIVLTGGSGHAFKLSPAYGELAAQLAVGNTSP
CCCCCCEEEEEEEEECCCCCCHHHCCCCEEEEECCCCCEEEECCCHHHHHHHHCCCCCCC
LYSEDFRIASHEPIKEAVHV
CCCCCCEECCCCCHHHHHCC
>Mature Secondary Structure
MKIAVIGLGSTGSMALWHLSNIPGVEAIGFEQFGISHGYGAFTGESRLFRMAYHEGSTYV
CEEEEEEECCCCCEEEEEECCCCCCEEECHHHCCCCCCCCCCCCCCCEEEEEECCCCEEH
PLLKRAQALWSSLSEISGRELFHNFGVLSTGKEDEAPFQRLVESVERYELPHERLTAAEM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
RKRYPGLDFRDEEAGIVDLQGGALRPELAVFSAIEAAKANGAQVRDHQKITSIEDKGDHV
HHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCEE
VIQAGEETTIVDRVIVTTGSWTSELVPSIAPLLEVRRLVLTWFLPTNPVDFQPENLPCFI
EEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCEEE
RDRDGFHVFGAPCVDGYSIKIAGLDEWGVPLSAHVEDEDLRLDRDAVSEFGRKTHELFPG
ECCCCCEEECCCCCCCEEEEEEECCCCCCCEEEECCHHHHCCCHHHHHHHHHHHHHHCCC
VNPEPNRFSVHYDTYTADKSPIIDAVDNVIVLTGGSGHAFKLSPAYGELAAQLAVGNTSP
CCCCCCEEEEEEEEECCCCCCHHHCCCCEEEEECCCCCEEEECCCHHHHHHHHCCCCCCC
LYSEDFRIASHEPIKEAVHV
CCCCCCEECCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]