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The map label for this gene is iap [H]

Identifier: 145295669

GI number: 145295669

Start: 1766147

End: 1767979

Strand: Reverse

Name: iap [H]

Synonym: cgR_1596

Alternate gene names: 145295669

Gene position: 1767979-1766147 (Counterclockwise)

Preceding gene: 145295670

Following gene: 145295668

Centisome position: 53.35

GC content: 57.72

Gene sequence:

>1833_bases
GTGGCCAATCTAGATTCAGTTCGCCCTGGGGTGCGGGCAGCTCTTCGACGTACCCATACCCAGGTAAAAGGTGTCGCGTT
GACCAGGGCATTGATTGCGCTTGCAGTAAGCGGAGCTTTGCTTAGTTCCATGACTCCGGCGGTGGCGCAGCCACAGAATC
CGGATGACGCAGCCATTGCACAGGCAGAGGAAAATGTTTCGGCGGGCGATGGGGAAGTCGCCCGCCTGGCAGGATCTTTG
TCCAGCACTGACGCGGAAATTAACCGCGTCGAGCTGGAAATGGGTGCTCTGCGTGAAGAAGTGAACAAGTCCCTCGTGGA
TTTGCATGATGCGCAGGCAATCGCCGAGCAGGCCCGCCAAGATGCTCTTGCAGCCAAGAAGGATCTCGATGATTCTCAAG
CGCAGATCGAAGCAGCCCAAGAGCGCCTTGATGAGATTTCACGTGCAGCGTATCGCCAAAACGGAACCTCCAAGGGGCTT
TCCGGCATCTCGGGCAATGGAAATTCTGAAGATGCGCTAGATCGTCAGACTTACCTGCGAACCAGTGCGGAAAAGCAGCA
GGCAGCTGTTGAAGAGCTTGATCGCCTCCGTACGGAAAACGCCAACAAGGAATCGGTGTTGCGCCAGGCCCGCATCGTTG
CTGAGCAGCGTGAGGCGGAAGCCGTCGAAAAGCAAGTCCAGACCGAGGCTGCAATTGCCGCAAACAGCGAGCAGCTCAAT
GTCTTGACTAACAATCGCAGTACCTTGGTTGCCCAGCGTGATGAGGCTGAGCGTAACTTGGCCATCGCTCGTGCGCAGGC
GGATAATCTGCAAGGTCAGCGTGCTGAGTACGAGGAATTCCAGCAGGCAGAGCAGGCTCGCATCCAGGCGGAAGCGGAAG
CTCAGGCTGCTGCGGAGGAGAAGCGTCGTGCCGATGAGGCTGCTGCACAGGCAGCCGCTGAAGCTCAAGAGGCTGCCCAG
CAAGCTCAGGCAGCGGAGGAAGCCCAAGCCGCGCAAGCAGCTGAGACAGCACAAGCACAAGCCGCGCAAGCTCAGGCAGC
GCAAGCTGTTCAGGCAGAAGCGAATGATCGTGCCGCCGCGCAACAGCGTGCTGCAGAGGCTCAAGCAGCAGCGGAACAGG
CGCAACGTGAGGCTGACGCTCAGGCGGCCAACGATGCCCAAGCTCAGGCACTGCGTGAACAGGCGCTCACCGCAGCCTCC
ATCGCTGCGGCTGCTCTGATTGCGGCGAGCCAGTCCAGCCACGCCACTACTCAAAATCCTTACCCAACTGATGAAGACGC
GGATCCAACCGACATTGCGGACATCCAAGGCCCAACGCAGCCAGGTACGGGTGAGTATGGAGATTCCCAGAACAACTCCA
GCGACAACGATTCCACAAGCTCAGATTCTTCAGAGGTTATTTCCGGCGATCGTTCCGCTCAGATTGAGACTGTGATTGCG
CGCGCCATGAGCCAGTTGGGTGTCCAGTACGCATGGGGTGGCGGTAACGCTAATGGCCCAACGTTAGGTATCCGTGACGG
CGGCGTGGCGGATTCTTACGGCGATTACAACAAGGTTGGCTTCGACTGCTCCGGATTGACCTTGTACGCGTTTGCGGGTG
TGGGAATTTCACTTCCTCACTACACGGGCTACCAATACCAGCACGGCACCAAGGTGGCGCCCTCTGAGATGCAACGTGGC
GATTTGATCTTCTATGGTCCGGGAGCATCCCAACACGTAGCAATTTACCTTGGTGATGGTCAGATGATTGAGGCTCCGAA
TTCGGGTTCTGTCGTGAAGATTTCTCCTGTTCGCTGGAGTGGAATGACTGAGAGTGTGGTACGCCTCATTTAG

Upstream 100 bases:

>100_bases
TTTCCGCTACGGAACGCGGAGTCTTTACGTTTCAATTCTTGGCAAGTGTCTAGCGTCAAGGCTTGATATGTGAAGGGATT
CGGATTGAACAGGAGAACAT

Downstream 100 bases:

>100_bases
TTTCATCCTATGAATCTTGGTGTGGTTCATGCGTTTTTATGCAATATCAATCAAAAGTTGGTACGATGCTCGTATGAATG
AACGCACATCGGATGCATTT

Product: hypothetical protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MANLDSVRPGVRAALRRTHTQVKGVALTRALIALAVSGALLSSMTPAVAQPQNPDDAAIAQAEENVSAGDGEVARLAGSL
SSTDAEINRVELEMGALREEVNKSLVDLHDAQAIAEQARQDALAAKKDLDDSQAQIEAAQERLDEISRAAYRQNGTSKGL
SGISGNGNSEDALDRQTYLRTSAEKQQAAVEELDRLRTENANKESVLRQARIVAEQREAEAVEKQVQTEAAIAANSEQLN
VLTNNRSTLVAQRDEAERNLAIARAQADNLQGQRAEYEEFQQAEQARIQAEAEAQAAAEEKRRADEAAAQAAAEAQEAAQ
QAQAAEEAQAAQAAETAQAQAAQAQAAQAVQAEANDRAAAQQRAAEAQAAAEQAQREADAQAANDAQAQALREQALTAAS
IAAAALIAASQSSHATTQNPYPTDEDADPTDIADIQGPTQPGTGEYGDSQNNSSDNDSTSSDSSEVISGDRSAQIETVIA
RAMSQLGVQYAWGGGNANGPTLGIRDGGVADSYGDYNKVGFDCSGLTLYAFAGVGISLPHYTGYQYQHGTKVAPSEMQRG
DLIFYGPGASQHVAIYLGDGQMIEAPNSGSVVKISPVRWSGMTESVVRLI

Sequences:

>Translated_610_residues
MANLDSVRPGVRAALRRTHTQVKGVALTRALIALAVSGALLSSMTPAVAQPQNPDDAAIAQAEENVSAGDGEVARLAGSL
SSTDAEINRVELEMGALREEVNKSLVDLHDAQAIAEQARQDALAAKKDLDDSQAQIEAAQERLDEISRAAYRQNGTSKGL
SGISGNGNSEDALDRQTYLRTSAEKQQAAVEELDRLRTENANKESVLRQARIVAEQREAEAVEKQVQTEAAIAANSEQLN
VLTNNRSTLVAQRDEAERNLAIARAQADNLQGQRAEYEEFQQAEQARIQAEAEAQAAAEEKRRADEAAAQAAAEAQEAAQ
QAQAAEEAQAAQAAETAQAQAAQAQAAQAVQAEANDRAAAQQRAAEAQAAAEQAQREADAQAANDAQAQALREQALTAAS
IAAAALIAASQSSHATTQNPYPTDEDADPTDIADIQGPTQPGTGEYGDSQNNSSDNDSTSSDSSEVISGDRSAQIETVIA
RAMSQLGVQYAWGGGNANGPTLGIRDGGVADSYGDYNKVGFDCSGLTLYAFAGVGISLPHYTGYQYQHGTKVAPSEMQRG
DLIFYGPGASQHVAIYLGDGQMIEAPNSGSVVKISPVRWSGMTESVVRLI
>Mature_609_residues
ANLDSVRPGVRAALRRTHTQVKGVALTRALIALAVSGALLSSMTPAVAQPQNPDDAAIAQAEENVSAGDGEVARLAGSLS
STDAEINRVELEMGALREEVNKSLVDLHDAQAIAEQARQDALAAKKDLDDSQAQIEAAQERLDEISRAAYRQNGTSKGLS
GISGNGNSEDALDRQTYLRTSAEKQQAAVEELDRLRTENANKESVLRQARIVAEQREAEAVEKQVQTEAAIAANSEQLNV
LTNNRSTLVAQRDEAERNLAIARAQADNLQGQRAEYEEFQQAEQARIQAEAEAQAAAEEKRRADEAAAQAAAEAQEAAQQ
AQAAEEAQAAQAAETAQAQAAQAQAAQAVQAEANDRAAAQQRAAEAQAAAEQAQREADAQAANDAQAQALREQALTAASI
AAAALIAASQSSHATTQNPYPTDEDADPTDIADIQGPTQPGTGEYGDSQNNSSDNDSTSSDSSEVISGDRSAQIETVIAR
AMSQLGVQYAWGGGNANGPTLGIRDGGVADSYGDYNKVGFDCSGLTLYAFAGVGISLPHYTGYQYQHGTKVAPSEMQRGD
LIFYGPGASQHVAIYLGDGQMIEAPNSGSVVKISPVRWSGMTESVVRLI

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=141, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787944, Length=122, Percent_Identity=32.7868852459016, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 64136; Mature: 64005

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLDSVRPGVRAALRRTHTQVKGVALTRALIALAVSGALLSSMTPAVAQPQNPDDAAIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
QAEENVSAGDGEVARLAGSLSSTDAEINRVELEMGALREEVNKSLVDLHDAQAIAEQARQ
HHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALAAKKDLDDSQAQIEAAQERLDEISRAAYRQNGTSKGLSGISGNGNSEDALDRQTYLR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
TSAEKQQAAVEELDRLRTENANKESVLRQARIVAEQREAEAVEKQVQTEAAIAANSEQLN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VLTNNRSTLVAQRDEAERNLAIARAQADNLQGQRAEYEEFQQAEQARIQAEAEAQAAAEE
EEECCCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRRADEAAAQAAAEAQEAAQQAQAAEEAQAAQAAETAQAQAAQAQAAQAVQAEANDRAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QQRAAEAQAAAEQAQREADAQAANDAQAQALREQALTAASIAAAALIAASQSSHATTQNP
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YPTDEDADPTDIADIQGPTQPGTGEYGDSQNNSSDNDSTSSDSSEVISGDRSAQIETVIA
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHH
RAMSQLGVQYAWGGGNANGPTLGIRDGGVADSYGDYNKVGFDCSGLTLYAFAGVGISLPH
HHHHHCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEECCC
YTGYQYQHGTKVAPSEMQRGDLIFYGPGASQHVAIYLGDGQMIEAPNSGSVVKISPVRWS
CCCCCCCCCCCCCHHHHCCCCEEEECCCCCCEEEEEECCCCEEECCCCCCEEEEECCCCC
GMTESVVRLI
CHHHHHHHHC
>Mature Secondary Structure 
ANLDSVRPGVRAALRRTHTQVKGVALTRALIALAVSGALLSSMTPAVAQPQNPDDAAIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
QAEENVSAGDGEVARLAGSLSSTDAEINRVELEMGALREEVNKSLVDLHDAQAIAEQARQ
HHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALAAKKDLDDSQAQIEAAQERLDEISRAAYRQNGTSKGLSGISGNGNSEDALDRQTYLR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
TSAEKQQAAVEELDRLRTENANKESVLRQARIVAEQREAEAVEKQVQTEAAIAANSEQLN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VLTNNRSTLVAQRDEAERNLAIARAQADNLQGQRAEYEEFQQAEQARIQAEAEAQAAAEE
EEECCCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRRADEAAAQAAAEAQEAAQQAQAAEEAQAAQAAETAQAQAAQAQAAQAVQAEANDRAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QQRAAEAQAAAEQAQREADAQAANDAQAQALREQALTAASIAAAALIAASQSSHATTQNP
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YPTDEDADPTDIADIQGPTQPGTGEYGDSQNNSSDNDSTSSDSSEVISGDRSAQIETVIA
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHH
RAMSQLGVQYAWGGGNANGPTLGIRDGGVADSYGDYNKVGFDCSGLTLYAFAGVGISLPH
HHHHHCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEECCC
YTGYQYQHGTKVAPSEMQRGDLIFYGPGASQHVAIYLGDGQMIEAPNSGSVVKISPVRWS
CCCCCCCCCCCCCHHHHCCCCEEEECCCCCCEEEEEECCCCEEECCCCCCEEEEECCCCC
GMTESVVRLI
CHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2111287; 1459966; 11679669 [H]