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The map label for this gene is apeB [H]

Identifier: 145295632

GI number: 145295632

Start: 1723944

End: 1725269

Strand: Reverse

Name: apeB [H]

Synonym: cgR_1559

Alternate gene names: 145295632

Gene position: 1725269-1723944 (Counterclockwise)

Preceding gene: 145295635

Following gene: 145295631

Centisome position: 52.06

GC content: 54.98

Gene sequence:

>1326_bases
GTGGATTCGCATTGTGGATTCGGGGGCCCGCGCTGTTTCCAAGAATTTGGCTACCCTTGTTCTATGCATGTAACTGACGA
TTTCTTAAGTTTTATTGCCCTAAGCCCAAGTTCCTATCACGCGGCCGCGGCGGTGGAGCGCAGGTTGCTCCATGAGGGGT
TCATTCGTCAGGAAGATACCGATGAATGGGATGCCCGCCCTGGTGGGCATGTGACGGTGCGTGGGGGAGCAGTAGTGGCG
TGGTGGGTGCCTGAGGATGCTTCGCCAGATTCCGGGTTCCGCATCATTGGGTCACATACTGATTCACCGGGTTTCAAGTT
AAAGCCCCGTGGGGATCTTTCCTCACACGGTTGGCAGCAGGCCGGCGTCGAGGTTTACGGCGGACCGATCCTGCCAAGCT
GGCTGGATCGCGAGCTGGCCTTAGCAGGCCGCATTGTGCTTGCCGACGGGTCCGTCAAGCTTGTCAACACCGGCCCGATT
CTGCGCATCCCGCACGTGGCTATTCATTTGGACCGTACTGTTAATTCCCAATTCACCCTTAATCCACAGCGTCACCTGCA
GCCTGTGTTTGCTGTTGGTGAGCCCGACGTATCAATTCTGGATGTCATTGCTGGTGCTGCGGTAGTGGATCCTGCAGATA
TTGTCAGTCATGATCTGATCACGGTGGCTACCCAAGATGCTGAAGTATTTGGCGCACATGGGGATTTCTTGGCGTCTGGT
CGCCTGGATAACCTGAGCAGCGTGCATCCATCCATGACTGCATTGATTGCGGCTTCGCAATCTGACGATACTGGTTCGGA
TATTTTGGTTCTTGCTGCATTCGATCATGAAGAAGTGGGAAGTAATTCCACCTCGGGTGCCGGGGGTCCCCTGTTGGAGG
ATGTACTCAACCGTACTGCTCGCGCGTTGGGTGCAGATGAAGATGAGCGACGCCGGATGTTTAACCGTTCCACCATGGTC
TCAGCTGACGCGGCACACTCCATTCACCCCAACTTCCCCGAGAAGCATGATCAAGCTAATTACCCCATCATTGGTAAAGG
TCCTGTATTGAAGGTCAACGCCAACCAGCGCTACACCTCCGATGCAGTCACTTCAGGCATGTGGATCAGGGCATGTCAGA
TTGCCGGTGTGCCACACCAGGTGTTTGCCGGCAACAACGATGTGCCGTGTGGTTCCACCATCGGCCCGATCAGTGCGACT
CGCCTGGGTATCGATTCTGTCGATGTCGGTATTCCATTGCTGTCCATGCACTCCGCACGCGAAATGGCCGGAGTGAAGGA
TCTGATGTGGTTTGAACAAGCCCTGGAAGCCTATCTGGTAAATTAA

Upstream 100 bases:

>100_bases
GCGCGCGACGGTGACAGCGCCAATGGGCGTGGCTTTTTCTTAACGTTTTCAACTGGGCTGGTCATAATGAACACCTACTT
TAACGGCTTCAGGTGACATT

Downstream 100 bases:

>100_bases
CGCCGAGTTCAATCAAGACAAGCACACAGAAGAAAGTGAGGGCTCATGCCCTACTCAGGTCCGTTCCAAGCAGGCGACCG
CGTTCAGCTCACAGACGCTA

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MDSHCGFGGPRCFQEFGYPCSMHVTDDFLSFIALSPSSYHAAAAVERRLLHEGFIRQEDTDEWDARPGGHVTVRGGAVVA
WWVPEDASPDSGFRIIGSHTDSPGFKLKPRGDLSSHGWQQAGVEVYGGPILPSWLDRELALAGRIVLADGSVKLVNTGPI
LRIPHVAIHLDRTVNSQFTLNPQRHLQPVFAVGEPDVSILDVIAGAAVVDPADIVSHDLITVATQDAEVFGAHGDFLASG
RLDNLSSVHPSMTALIAASQSDDTGSDILVLAAFDHEEVGSNSTSGAGGPLLEDVLNRTARALGADEDERRRMFNRSTMV
SADAAHSIHPNFPEKHDQANYPIIGKGPVLKVNANQRYTSDAVTSGMWIRACQIAGVPHQVFAGNNDVPCGSTIGPISAT
RLGIDSVDVGIPLLSMHSAREMAGVKDLMWFEQALEAYLVN

Sequences:

>Translated_441_residues
MDSHCGFGGPRCFQEFGYPCSMHVTDDFLSFIALSPSSYHAAAAVERRLLHEGFIRQEDTDEWDARPGGHVTVRGGAVVA
WWVPEDASPDSGFRIIGSHTDSPGFKLKPRGDLSSHGWQQAGVEVYGGPILPSWLDRELALAGRIVLADGSVKLVNTGPI
LRIPHVAIHLDRTVNSQFTLNPQRHLQPVFAVGEPDVSILDVIAGAAVVDPADIVSHDLITVATQDAEVFGAHGDFLASG
RLDNLSSVHPSMTALIAASQSDDTGSDILVLAAFDHEEVGSNSTSGAGGPLLEDVLNRTARALGADEDERRRMFNRSTMV
SADAAHSIHPNFPEKHDQANYPIIGKGPVLKVNANQRYTSDAVTSGMWIRACQIAGVPHQVFAGNNDVPCGSTIGPISAT
RLGIDSVDVGIPLLSMHSAREMAGVKDLMWFEQALEAYLVN
>Mature_441_residues
MDSHCGFGGPRCFQEFGYPCSMHVTDDFLSFIALSPSSYHAAAAVERRLLHEGFIRQEDTDEWDARPGGHVTVRGGAVVA
WWVPEDASPDSGFRIIGSHTDSPGFKLKPRGDLSSHGWQQAGVEVYGGPILPSWLDRELALAGRIVLADGSVKLVNTGPI
LRIPHVAIHLDRTVNSQFTLNPQRHLQPVFAVGEPDVSILDVIAGAAVVDPADIVSHDLITVATQDAEVFGAHGDFLASG
RLDNLSSVHPSMTALIAASQSDDTGSDILVLAAFDHEEVGSNSTSGAGGPLLEDVLNRTARALGADEDERRRMFNRSTMV
SADAAHSIHPNFPEKHDQANYPIIGKGPVLKVNANQRYTSDAVTSGMWIRACQIAGVPHQVFAGNNDVPCGSTIGPISAT
RLGIDSVDVGIPLLSMHSAREMAGVKDLMWFEQALEAYLVN

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=448, Percent_Identity=37.7232142857143, Blast_Score=285, Evalue=6e-77,
Organism=Caenorhabditis elegans, GI17552916, Length=430, Percent_Identity=35.1162790697674, Blast_Score=234, Evalue=9e-62,
Organism=Saccharomyces cerevisiae, GI6321905, Length=468, Percent_Identity=35.2564102564103, Blast_Score=277, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6322746, Length=453, Percent_Identity=27.1523178807947, Blast_Score=166, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 47242; Mature: 47242

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSHCGFGGPRCFQEFGYPCSMHVTDDFLSFIALSPSSYHAAAAVERRLLHEGFIRQEDT
CCCCCCCCCHHHHHHHCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCC
DEWDARPGGHVTVRGGAVVAWWVPEDASPDSGFRIIGSHTDSPGFKLKPRGDLSSHGWQQ
CCCCCCCCCEEEEECCEEEEEECCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCHHH
AGVEVYGGPILPSWLDRELALAGRIVLADGSVKLVNTGPILRIPHVAIHLDRTVNSQFTL
CCEEEECCCCCHHHHCCHHHHCCEEEEECCCEEEEECCCEEECCEEEEEEECCCCCEEEE
NPQRHLQPVFAVGEPDVSILDVIAGAAVVDPADIVSHDLITVATQDAEVFGAHGDFLASG
CHHHHCCEEEEECCCCHHHHHHHHCCHHCCHHHHHCCCEEEEEECCCCEECCCCCEEECC
RLDNLSSVHPSMTALIAASQSDDTGSDILVLAAFDHEEVGSNSTSGAGGPLLEDVLNRTA
CCCCCHHCCCCEEEEEEECCCCCCCCCEEEEEEECHHHCCCCCCCCCCCHHHHHHHHHHH
RALGADEDERRRMFNRSTMVSADAAHSIHPNFPEKHDQANYPIIGKGPVLKVNANQRYTS
HHHCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCH
DAVTSGMWIRACQIAGVPHQVFAGNNDVPCGSTIGPISATRLGIDSVDVGIPLLSMHSAR
HHHHCCCEEEEEEECCCCHHEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHH
EMAGVKDLMWFEQALEAYLVN
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSHCGFGGPRCFQEFGYPCSMHVTDDFLSFIALSPSSYHAAAAVERRLLHEGFIRQEDT
CCCCCCCCCHHHHHHHCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCC
DEWDARPGGHVTVRGGAVVAWWVPEDASPDSGFRIIGSHTDSPGFKLKPRGDLSSHGWQQ
CCCCCCCCCEEEEECCEEEEEECCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCHHH
AGVEVYGGPILPSWLDRELALAGRIVLADGSVKLVNTGPILRIPHVAIHLDRTVNSQFTL
CCEEEECCCCCHHHHCCHHHHCCEEEEECCCEEEEECCCEEECCEEEEEEECCCCCEEEE
NPQRHLQPVFAVGEPDVSILDVIAGAAVVDPADIVSHDLITVATQDAEVFGAHGDFLASG
CHHHHCCEEEEECCCCHHHHHHHHCCHHCCHHHHHCCCEEEEEECCCCEECCCCCEEECC
RLDNLSSVHPSMTALIAASQSDDTGSDILVLAAFDHEEVGSNSTSGAGGPLLEDVLNRTA
CCCCCHHCCCCEEEEEEECCCCCCCCCEEEEEEECHHHCCCCCCCCCCCHHHHHHHHHHH
RALGADEDERRRMFNRSTMVSADAAHSIHPNFPEKHDQANYPIIGKGPVLKVNANQRYTS
HHHCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCH
DAVTSGMWIRACQIAGVPHQVFAGNNDVPCGSTIGPISATRLGIDSVDVGIPLLSMHSAR
HHHHCCCEEEEEEECCCCHHEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHH
EMAGVKDLMWFEQALEAYLVN
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]