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The map label for this gene is ytfL [C]

Identifier: 145295581

GI number: 145295581

Start: 1669816

End: 1670880

Strand: Reverse

Name: ytfL [C]

Synonym: cgR_1508

Alternate gene names: 145295581

Gene position: 1670880-1669816 (Counterclockwise)

Preceding gene: 145295582

Following gene: 145295580

Centisome position: 50.42

GC content: 55.12

Gene sequence:

>1065_bases
GTGAGTATTTGGGCAACTGTCCTTCTAATTATCGTCCTTCTTTCCGCCAACGCCTTCTTCGTGGCCGCGGAGTTCGCACT
GATTTCCTCGCGCCGGGACCGCCTGGATTCCCTGGTATCCCAGGGTAAAAAGGGAGCTGAAAAGGTTCTCTACGCAACCG
AGCACCTGTCCATCATGTTGGCGGGCGCTCAGTTCGGTATTACGGTCTGTTCTCTGATTCTGGGTAAAGTCGCAGAACCT
GCGATCGCCCACTTCATTGAGGTGCCTTTCACCTCCTGGGGTGTTCCAAATGATTTGATCCACCCAATTTCCTTCGTCAT
CGCACTGGCGATCATCACCTGGTTGCACATTCTCTTTGGTGAAATGGTGCCAAAGAACATCGCTATTGCTGGCCCTGAAA
CCTTAGGCATGTGGCTTGCTCCAGTGCTCATTGCGTTTGTGAAGATTACCCGCCCGTTGATCGAGTTCATGAACTGGATC
GCCCGTCTGACCCTTCGCGCCTTTGGTGTGGAGCAAAAAGACGAGCTGGATTCCACCGTCGACCCAGAGCAGCTGGCATC
AATGATTTCCGAGTCCCGTTCCGAAGGCCTCCTTGATGCTGAAGAGCACGCCCGCCTGTCCAAGGCGCTGCGCTCTGAGC
AGCGTTCCATCAAGGAACTGGTGATTAAGGATGAGGACGTGCGCACGCTGGCGTTCGGTAAATCTGGCCCGACCTTGCAC
CAGTTGGAGGAAGCAGTCCGCGAGACCGGTTTCTCCCGCTTCCCTGTCACCGGCCGCGATGGATCCTACTTGGGTTATAT
CCACATCAAGGATATTTTGCCTCGTCTGGCTGATCCTGAGATGGATCCCTCCGAGACCATTCCGCGTTCTGCACTGCGCC
CTTTGAGCAATGTGGATGCCGATGGCCTCATGGATGACGTCTTGGATTTTATGCACCACCGCTCCGCGCACATGGCTCAG
GTTCGCCTCAAAGGTGAGCTTCTCGGCGTGATTACGCTGGAGGATCTCATCGAAGAATACGTGGGCACCGTCAACGATTG
GACTCACGAAAGCTCCGACGACTAG

Upstream 100 bases:

>100_bases
CAGGACGCTGGATCGCACGAGTAACGGTCATGGAAGATCGACGCATCGACAAAGCCGTTCTCACCCCCATCACCCATGAA
GAAGCAAAGGAGTACGAAAA

Downstream 100 bases:

>100_bases
AAATAGTAACTGTGTTGGACACTTTTCACCTCAGCGTATTGAGCGAGGATGAGTGGATGGAACTAGCCCGCGCCCACCAC
GCGCGGGCTGATTCATTCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSIWATVLLIIVLLSANAFFVAAEFALISSRRDRLDSLVSQGKKGAEKVLYATEHLSIMLAGAQFGITVCSLILGKVAEP
AIAHFIEVPFTSWGVPNDLIHPISFVIALAIITWLHILFGEMVPKNIAIAGPETLGMWLAPVLIAFVKITRPLIEFMNWI
ARLTLRAFGVEQKDELDSTVDPEQLASMISESRSEGLLDAEEHARLSKALRSEQRSIKELVIKDEDVRTLAFGKSGPTLH
QLEEAVRETGFSRFPVTGRDGSYLGYIHIKDILPRLADPEMDPSETIPRSALRPLSNVDADGLMDDVLDFMHHRSAHMAQ
VRLKGELLGVITLEDLIEEYVGTVNDWTHESSDD

Sequences:

>Translated_354_residues
MSIWATVLLIIVLLSANAFFVAAEFALISSRRDRLDSLVSQGKKGAEKVLYATEHLSIMLAGAQFGITVCSLILGKVAEP
AIAHFIEVPFTSWGVPNDLIHPISFVIALAIITWLHILFGEMVPKNIAIAGPETLGMWLAPVLIAFVKITRPLIEFMNWI
ARLTLRAFGVEQKDELDSTVDPEQLASMISESRSEGLLDAEEHARLSKALRSEQRSIKELVIKDEDVRTLAFGKSGPTLH
QLEEAVRETGFSRFPVTGRDGSYLGYIHIKDILPRLADPEMDPSETIPRSALRPLSNVDADGLMDDVLDFMHHRSAHMAQ
VRLKGELLGVITLEDLIEEYVGTVNDWTHESSDD
>Mature_353_residues
SIWATVLLIIVLLSANAFFVAAEFALISSRRDRLDSLVSQGKKGAEKVLYATEHLSIMLAGAQFGITVCSLILGKVAEPA
IAHFIEVPFTSWGVPNDLIHPISFVIALAIITWLHILFGEMVPKNIAIAGPETLGMWLAPVLIAFVKITRPLIEFMNWIA
RLTLRAFGVEQKDELDSTVDPEQLASMISESRSEGLLDAEEHARLSKALRSEQRSIKELVIKDEDVRTLAFGKSGPTLHQ
LEEAVRETGFSRFPVTGRDGSYLGYIHIKDILPRLADPEMDPSETIPRSALRPLSNVDADGLMDDVLDFMHHRSAHMAQV
RLKGELLGVITLEDLIEEYVGTVNDWTHESSDD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=338, Percent_Identity=29.8816568047337, Blast_Score=145, Evalue=7e-35,
Organism=Escherichia coli, GI1790664, Length=274, Percent_Identity=24.0875912408759, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI145693175, Length=336, Percent_Identity=22.0238095238095, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR002550 [H]

Pfam domain/function: PF00571 CBS; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 39231; Mature: 39100

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIWATVLLIIVLLSANAFFVAAEFALISSRRDRLDSLVSQGKKGAEKVLYATEHLSIML
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEE
AGAQFGITVCSLILGKVAEPAIAHFIEVPFTSWGVPNDLIHPISFVIALAIITWLHILFG
ECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EMVPKNIAIAGPETLGMWLAPVLIAFVKITRPLIEFMNWIARLTLRAFGVEQKDELDSTV
HHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
DPEQLASMISESRSEGLLDAEEHARLSKALRSEQRSIKELVIKDEDVRTLAFGKSGPTLH
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHH
QLEEAVRETGFSRFPVTGRDGSYLGYIHIKDILPRLADPEMDPSETIPRSALRPLSNVDA
HHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCHHCCCHHHHCHHHCCCC
DGLMDDVLDFMHHRSAHMAQVRLKGELLGVITLEDLIEEYVGTVNDWTHESSDD
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCC
>Mature Secondary Structure 
SIWATVLLIIVLLSANAFFVAAEFALISSRRDRLDSLVSQGKKGAEKVLYATEHLSIML
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEE
AGAQFGITVCSLILGKVAEPAIAHFIEVPFTSWGVPNDLIHPISFVIALAIITWLHILFG
ECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EMVPKNIAIAGPETLGMWLAPVLIAFVKITRPLIEFMNWIARLTLRAFGVEQKDELDSTV
HHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
DPEQLASMISESRSEGLLDAEEHARLSKALRSEQRSIKELVIKDEDVRTLAFGKSGPTLH
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHH
QLEEAVRETGFSRFPVTGRDGSYLGYIHIKDILPRLADPEMDPSETIPRSALRPLSNVDA
HHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCHHCCCHHHHCHHHCCCC
DGLMDDVLDFMHHRSAHMAQVRLKGELLGVITLEDLIEEYVGTVNDWTHESSDD
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]