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The map label for this gene is ybeX [C]

Identifier: 145295582

GI number: 145295582

Start: 1670877

End: 1672259

Strand: Reverse

Name: ybeX [C]

Synonym: cgR_1509

Alternate gene names: 145295582

Gene position: 1672259-1670877 (Counterclockwise)

Preceding gene: 145295583

Following gene: 145295581

Centisome position: 50.46

GC content: 55.39

Gene sequence:

>1383_bases
ATGGACATACTCATAAGCATCCTCTCACTGCTAGGCTTCGTGCTTCTTACCGCGAGCACCGGACTATTCGTGGCCATTGA
GTTCGCACTCACCGGCTTAGAAAAATCCACTGTAGAAACACATGTGAAGCAAAAAGGCGACAGCAGCGCCCGCGCAGTGC
AGAGGGATCATCAAAATCTGTCGTTCGTGCTCTCTGGTGCCCAGCTGGGTATCACGATCACGACACTTGCCACAGGCTTC
CTCGCAGAGCCGGTTTTGGCCAAATTCTTCACCCCAGCACTTGAGCTGGTGGGATTAAATGAATCAGCAAGCTCCGCAGT
AGCCCTCATCATCGCACTGTTGGTGGCAACTACCCTCTCCATGGTTTTTGGTGAGTTGGTTCCCAAAAACTGGGCGATCA
CCAACCCGTTGGGCGTGGCACGTTTTGTTGTCCACCCTGTCAATTGGTTCAACATGGTTCTCAAGCCGTTTATTAACGGC
ATGAACAAGTCTGCAAACTTTATTGTCCGCAAACTTGGTATTGAACCAGCCGAAGAACTTGCCTCTGCCCGTTCCTCCCA
AGAGCTCACCGCCTTGGTACGCAGTTCCGCGGAAAGCGGCGGACTGGATCAAAACACCGCAGCAGTGATCAACCGATCCC
TGCAGTTCGGTGACGCCACCGCTGATGAATTCATGACACCTCGCTCCACCATTGAATCATTGCGTGCAACAGACACCGTC
AATGATTTGATCGAGCTTGCCCTGGAAACGGGCCACTCCCGCTTCCCAGTCACCGAAGGCGACTTGGATGAAACCATCGG
CATGGTCCACATCAAGGACGCATTCTCTGTAGTGCAGGCAGAACGCGCCACCACCATGGTGCGCGATCTAGCCCGCAGAA
TTCCTGTGGTACCAGCCAGCCTTGACGGCGACTCTGTCCTCAACGCTGTCCGCTCCGCCGGCTCCCAAGTTATTTTGGTT
GCCGATGAATACGGCGGAACCGCAGGCATGGTCACCATCGAAGACGTCGTGGAGGAAATCCTCGGCGAAATCCACGATGA
GCACGACGACTCCGACGCCGAACGCGATTTCCAACAATTCGGCGCCAGCTGGGAAGTCTCCGGCCTGGTCCGCATCGATG
AACTCGAAAAACGCGTCGGGTACGTCTCCCCTGACGGCCCCTACGAAACCCTCGGCGGCTTGATCATGTACGCAGTCGGC
GCCATTCCTCGCGTTGGGGACGTCGCCCTACTCCCACTGACCGATACCCCAACCATGGATGAATTCGAATCCGGCTTCTC
AGGACGCTGGATCGCACGAGTAACGGTCATGGAAGATCGACGCATCGACAAAGCCGTTCTCACCCCCATCACCCATGAAG
AAGCAAAGGAGTACGAAAAGTGA

Upstream 100 bases:

>100_bases
ACTTCAAGGAAAGACGGTCCCAAGAGCTAAAACTCCCCCACGGCACGCGAAGCTGAACAGGCTTTCACCGCTTCTAGGGG
CAACAGCTTAAACCACGCTA

Downstream 100 bases:

>100_bases
GTATTTGGGCAACTGTCCTTCTAATTATCGTCCTTCTTTCCGCCAACGCCTTCTTCGTGGCCGCGGAGTTCGCACTGATT
TCCTCGCGCCGGGACCGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MDILISILSLLGFVLLTASTGLFVAIEFALTGLEKSTVETHVKQKGDSSARAVQRDHQNLSFVLSGAQLGITITTLATGF
LAEPVLAKFFTPALELVGLNESASSAVALIIALLVATTLSMVFGELVPKNWAITNPLGVARFVVHPVNWFNMVLKPFING
MNKSANFIVRKLGIEPAEELASARSSQELTALVRSSAESGGLDQNTAAVINRSLQFGDATADEFMTPRSTIESLRATDTV
NDLIELALETGHSRFPVTEGDLDETIGMVHIKDAFSVVQAERATTMVRDLARRIPVVPASLDGDSVLNAVRSAGSQVILV
ADEYGGTAGMVTIEDVVEEILGEIHDEHDDSDAERDFQQFGASWEVSGLVRIDELEKRVGYVSPDGPYETLGGLIMYAVG
AIPRVGDVALLPLTDTPTMDEFESGFSGRWIARVTVMEDRRIDKAVLTPITHEEAKEYEK

Sequences:

>Translated_460_residues
MDILISILSLLGFVLLTASTGLFVAIEFALTGLEKSTVETHVKQKGDSSARAVQRDHQNLSFVLSGAQLGITITTLATGF
LAEPVLAKFFTPALELVGLNESASSAVALIIALLVATTLSMVFGELVPKNWAITNPLGVARFVVHPVNWFNMVLKPFING
MNKSANFIVRKLGIEPAEELASARSSQELTALVRSSAESGGLDQNTAAVINRSLQFGDATADEFMTPRSTIESLRATDTV
NDLIELALETGHSRFPVTEGDLDETIGMVHIKDAFSVVQAERATTMVRDLARRIPVVPASLDGDSVLNAVRSAGSQVILV
ADEYGGTAGMVTIEDVVEEILGEIHDEHDDSDAERDFQQFGASWEVSGLVRIDELEKRVGYVSPDGPYETLGGLIMYAVG
AIPRVGDVALLPLTDTPTMDEFESGFSGRWIARVTVMEDRRIDKAVLTPITHEEAKEYEK
>Mature_460_residues
MDILISILSLLGFVLLTASTGLFVAIEFALTGLEKSTVETHVKQKGDSSARAVQRDHQNLSFVLSGAQLGITITTLATGF
LAEPVLAKFFTPALELVGLNESASSAVALIIALLVATTLSMVFGELVPKNWAITNPLGVARFVVHPVNWFNMVLKPFING
MNKSANFIVRKLGIEPAEELASARSSQELTALVRSSAESGGLDQNTAAVINRSLQFGDATADEFMTPRSTIESLRATDTV
NDLIELALETGHSRFPVTEGDLDETIGMVHIKDAFSVVQAERATTMVRDLARRIPVVPASLDGDSVLNAVRSAGSQVILV
ADEYGGTAGMVTIEDVVEEILGEIHDEHDDSDAERDFQQFGASWEVSGLVRIDELEKRVGYVSPDGPYETLGGLIMYAVG
AIPRVGDVALLPLTDTPTMDEFESGFSGRWIARVTVMEDRRIDKAVLTPITHEEAKEYEK

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=382, Percent_Identity=31.9371727748691, Blast_Score=204, Evalue=1e-52,
Organism=Escherichia coli, GI1786879, Length=224, Percent_Identity=32.1428571428571, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790664, Length=408, Percent_Identity=23.5294117647059, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI145693175, Length=376, Percent_Identity=25.531914893617, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI87082033, Length=382, Percent_Identity=24.6073298429319, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788119, Length=211, Percent_Identity=32.2274881516588, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49647; Mature: 49647

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILISILSLLGFVLLTASTGLFVAIEFALTGLEKSTVETHVKQKGDSSARAVQRDHQNL
CHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCE
SFVLSGAQLGITITTLATGFLAEPVLAKFFTPALELVGLNESASSAVALIIALLVATTLS
EEEEECCHHCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
MVFGELVPKNWAITNPLGVARFVVHPVNWFNMVLKPFINGMNKSANFIVRKLGIEPAEEL
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHH
ASARSSQELTALVRSSAESGGLDQNTAAVINRSLQFGDATADEFMTPRSTIESLRATDTV
HHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHH
NDLIELALETGHSRFPVTEGDLDETIGMVHIKDAFSVVQAERATTMVRDLARRIPVVPAS
HHHHHHHHHCCCCCCCCCCCCHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LDGDSVLNAVRSAGSQVILVADEYGGTAGMVTIEDVVEEILGEIHDEHDDSDAERDFQQF
CCHHHHHHHHHHCCCEEEEEEECCCCCCCEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHC
GASWEVSGLVRIDELEKRVGYVSPDGPYETLGGLIMYAVGAIPRVGDVALLPLTDTPTMD
CCCEEECCCEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHH
EFESGFSGRWIARVTVMEDRRIDKAVLTPITHEEAKEYEK
HHHCCCCCCEEEEEEEECCCCCCHHHHCCCCHHHHHHCCC
>Mature Secondary Structure
MDILISILSLLGFVLLTASTGLFVAIEFALTGLEKSTVETHVKQKGDSSARAVQRDHQNL
CHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCE
SFVLSGAQLGITITTLATGFLAEPVLAKFFTPALELVGLNESASSAVALIIALLVATTLS
EEEEECCHHCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
MVFGELVPKNWAITNPLGVARFVVHPVNWFNMVLKPFINGMNKSANFIVRKLGIEPAEEL
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHH
ASARSSQELTALVRSSAESGGLDQNTAAVINRSLQFGDATADEFMTPRSTIESLRATDTV
HHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHH
NDLIELALETGHSRFPVTEGDLDETIGMVHIKDAFSVVQAERATTMVRDLARRIPVVPAS
HHHHHHHHHCCCCCCCCCCCCHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LDGDSVLNAVRSAGSQVILVADEYGGTAGMVTIEDVVEEILGEIHDEHDDSDAERDFQQF
CCHHHHHHHHHHCCCEEEEEEECCCCCCCEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHC
GASWEVSGLVRIDELEKRVGYVSPDGPYETLGGLIMYAVGAIPRVGDVALLPLTDTPTMD
CCCEEECCCEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHH
EFESGFSGRWIARVTVMEDRRIDKAVLTPITHEEAKEYEK
HHHCCCCCCEEEEEEEECCCCCCHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]