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The map label for this gene is nadA [H]

Identifier: 145295211

GI number: 145295211

Start: 1260198

End: 1261484

Strand: Reverse

Name: nadA [H]

Synonym: cgR_1152

Alternate gene names: 145295211

Gene position: 1261484-1260198 (Counterclockwise)

Preceding gene: 145295212

Following gene: 145295210

Centisome position: 38.06

GC content: 56.1

Gene sequence:

>1287_bases
ATGACCACCTCAATCACCCCATCTGTCAACCTTGCACTGAAAAATGCCAATAGCTGCAACAGTGAACTCAAAGACGGACC
CTGGTTCCTCGACCAGCCCGGAATGCCGGATGTCTACGGCCCCGGCGCGTCACAAAACGATCCGATCCCTGCGCATGCTC
CGCGCCAGCAGGTTCTCCCCGAGGAGTACCAGCGCGCAAGTGATGACGAACTGCATCGTAGGATCCGGGAAGCGAAAGAC
ACCCTGGGTGACAAGGTGGTTATCCTAGGACACTTCTACCAGCGCGATGAAGTTATCCAACACGCAGATTTTGTTGGTGA
CTCTTTCCAACTTGCCCGCGCTGCCAAAACCCGCCCCGAAGCGGAAGCGATTGTGTTCTGCGGTGTGCACTTCATGGCTG
AAACCGCTGACCTGTTGTCCACGGATGAACAATCAGTGATCCTCCCCAACCTGGCCGCAGGTTGCTCCATGGCAGACATG
GCTGACCTTGATTCCGTCGAAGACTGCTGGGAGCAACTCACCTCAATTTATGGCGATGACACCCTGATCCCTGTGACCTA
CATGAATTCCTCTGCAGCGCTCAAAGGTTTCGTGGGTGAGCACGGCGGAATTGTGTGCACCTCCTCCAACGCACGTGCTG
TACTTGAGTGGGCGTTTGAACGCGGCCAACGAGTCCTGTTCTTCCCCGATCAGCACTTGGGTCGAAACACTGCGAAAGCC
ATGGGCATTGAACTTGATCAAATGCCCCTGTGGAACCCCAACAAACCACTGGGTGGCAACACCGTTTCCGAGCTAGAAAA
CGCAAAGGTACTGCTCTGGCATGGTTTCTGCTCTGTACACAAGCGCTTTACAGTCGAGCAAATCAACAAAGCCCGCGCCG
AGTACCCCGACGTTCACGTCATCGTGCACCCTGAATCCCCCATGCCAGTTGTTGACGCCGCCGACTCCTCCGGATCCACT
GACTTCATTGTGAAAGCCATTCAAGCAGCACCCGCAGGATCTACCTTTGCGATCGGCACCGAAATCAACTTGGTTCAGCG
CCTGGCAGCCCAGTACCCGCAGCACACCATCTTCTGCCTCGACCCTGTCATCTGCCCATGCTCCACGATGTACCGCATTC
ACCCTGGTTACCTGGCCTGGGCGCTTGAGGAGTTGGTGGCTGGAAACGTGATTAACCAGATTTCTGTCTCTGAATCTGTG
GCGGCACCGGCGCGTGTTGCCCTGGAGAGGATGCTGTCTGTTGTCCCAGCGGCTCCTGTTACTCCTAGCTCCTCGAAGGA
TGCGTAA

Upstream 100 bases:

>100_bases
GCTTGCGGGAACACCGCACCGCCCACCCAAACTGTTCAGATTCCAAAGATAAATTCTGACGCTCATTCCAGCCCACCGTT
TAGAAGAAAAGACCCCAATC

Downstream 100 bases:

>100_bases
TTTATGACTAACCATACTGACCGTATCGTTGGCGCAGCGTTATCCGAGGATGCGCCATGGGGCGACATTACCTCCGACAC
TTTTATCCCAGGATCGGCGC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTTSITPSVNLALKNANSCNSELKDGPWFLDQPGMPDVYGPGASQNDPIPAHAPRQQVLPEEYQRASDDELHRRIREAKD
TLGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPEAEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADM
ADLDSVEDCWEQLTSIYGDDTLIPVTYMNSSAALKGFVGEHGGIVCTSSNARAVLEWAFERGQRVLFFPDQHLGRNTAKA
MGIELDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHVIVHPESPMPVVDAADSSGST
DFIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCLDPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESV
AAPARVALERMLSVVPAAPVTPSSSKDA

Sequences:

>Translated_428_residues
MTTSITPSVNLALKNANSCNSELKDGPWFLDQPGMPDVYGPGASQNDPIPAHAPRQQVLPEEYQRASDDELHRRIREAKD
TLGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPEAEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADM
ADLDSVEDCWEQLTSIYGDDTLIPVTYMNSSAALKGFVGEHGGIVCTSSNARAVLEWAFERGQRVLFFPDQHLGRNTAKA
MGIELDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHVIVHPESPMPVVDAADSSGST
DFIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCLDPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESV
AAPARVALERMLSVVPAAPVTPSSSKDA
>Mature_427_residues
TTSITPSVNLALKNANSCNSELKDGPWFLDQPGMPDVYGPGASQNDPIPAHAPRQQVLPEEYQRASDDELHRRIREAKDT
LGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPEAEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADMA
DLDSVEDCWEQLTSIYGDDTLIPVTYMNSSAALKGFVGEHGGIVCTSSNARAVLEWAFERGQRVLFFPDQHLGRNTAKAM
GIELDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHVIVHPESPMPVVDAADSSGSTD
FIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCLDPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESVA
APARVALERMLSVVPAAPVTPSSSKDA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=340, Percent_Identity=28.5294117647059, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 46564; Mature: 46433

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSITPSVNLALKNANSCNSELKDGPWFLDQPGMPDVYGPGASQNDPIPAHAPRQQVLP
CCCCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
EEYQRASDDELHRRIREAKDTLGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPE
HHHHCCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
AEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADMADLDSVEDCWEQLTSIYGDD
CCEEEEECHHHHHHHHHHHCCCCCCEECCCHHCCCCCHHHHCCCHHHHHHHHHHHHCCCC
TLIPVTYMNSSAALKGFVGEHGGIVCTSSNARAVLEWAFERGQRVLFFPDQHLGRNTAKA
CEEEEEEECCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCEEEECCCHHCCCCHHHH
MGIELDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHV
HCCEECCCCCCCCCCCCCCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEE
IVHPESPMPVVDAADSSGSTDFIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCL
EECCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEE
DPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESVAAPARVALERMLSVVPAAPV
CCCCCCCCCCEEECCHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCC
TPSSSKDA
CCCCCCCC
>Mature Secondary Structure 
TTSITPSVNLALKNANSCNSELKDGPWFLDQPGMPDVYGPGASQNDPIPAHAPRQQVLP
CCCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
EEYQRASDDELHRRIREAKDTLGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPE
HHHHCCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
AEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADMADLDSVEDCWEQLTSIYGDD
CCEEEEECHHHHHHHHHHHCCCCCCEECCCHHCCCCCHHHHCCCHHHHHHHHHHHHCCCC
TLIPVTYMNSSAALKGFVGEHGGIVCTSSNARAVLEWAFERGQRVLFFPDQHLGRNTAKA
CEEEEEEECCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCEEEECCCHHCCCCHHHH
MGIELDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHV
HCCEECCCCCCCCCCCCCCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEE
IVHPESPMPVVDAADSSGSTDFIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCL
EECCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEE
DPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESVAAPARVALERMLSVVPAAPV
CCCCCCCCCCEEECCHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCC
TPSSSKDA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]