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The map label for this gene is serC

Identifier: 145294997

GI number: 145294997

Start: 1040532

End: 1041662

Strand: Reverse

Name: serC

Synonym: cgR_0942

Alternate gene names: 145294997

Gene position: 1041662-1040532 (Counterclockwise)

Preceding gene: 145295000

Following gene: 145294996

Centisome position: 31.43

GC content: 57.03

Gene sequence:

>1131_bases
ATGACCGACTTCCCCACCCTGCCCTCTGAGTTCATCCCTGGCGACGGCCGTTTCGGCTGCGGACCTTCCAAGGTTCGACC
AGAACAGATTCAGGCTATTGTCGACGGATCCGCATCCGTCATCGGTACCTCACACCGTCAGCCGGCAGTAAAAAACGTCG
TGGGTTCAATCCGCGAGGGACTCTCCGACCTCTTCTCCCTTCCAGAAGGCTACGAGATCATCCTTTCCCTAGGTGGTGCG
ACCGCATTCTGGGATGCAGCAACCTTCGGACTCATTGAAAAGAAGTCCGGTCACCTTTCTTTCGGTGAGTTCTCCTCCAA
GTTTGCAAAGGCTTCTAAGCTTGCTCCTTGGCTTTACGAGCCAGAGATCGTCACCGCAGAAACCGGTGACGCTCCGGCCC
CACAGGCATTCGAAGGCGCCGATGTTATTGCATGGGCACACAACGAAACCTCCACTGGCGCCATGGTTCCAGTTCTTCGC
CCCGAAGGCTCTGAAGGCTCCCTGGTTGCCATTGACGCAACCTCCGGCGCTGGTGGACTGCCAGTAGACATCAAGAACTC
CGATGTTTACTACTTCTCCCCACAGAAGTGCTTCGCATCCGACGGTGGCCTGTGGCTTGCAGCGATGAGCCCAGCAGCTC
TCGAGCGCATCGAGAAGATCAACGCTTCCGATCGCTTCATCCCTGAGTTCCTCAACCTGCAGACCGCAGTGGATAACTCC
CTGAAGAACCAGACCTACAACACCCCAGCTGTTGCTACCTTGCTGATGCTGGACAACCAGGTCAAGTGGATGAACTCCAA
CGGCGGCCTGGATGGAATGGTTGCTCGCACCACAGCAAGCTCCTCCGCCCTGTACAACTGGGCTGAGGCTCGCGAGGAGG
CATCCCCATACGTGGCAGATGCAGCTAAGCGCTCCCTCGTTGTCGGCACCATCGACTTCGATGACTCCATCGACGCAGCA
GTGATCGCTAAGATACTGCGCGCAAACGGCATCCTGGACACCGAGCCTTACCGCAAGCTGGGACGCAACCAGCTGCGCAT
CGGTATGTTCCCAGCGATCGATTCCACCGATGTGGAAAAGCTCACCGGAGCAATCGACTTCATCCTCGATGGCGGTTTTG
CAAAGAAGTAA

Upstream 100 bases:

>100_bases
GGGTGCTAGGAACTGACAGCTTCAGGGTTATAGTTGTTGGGTCAGATCGTTAACGATCCCTGGCCCTTTTACTTCCAAGC
GCAGAAAGTTGCCCGAAGAC

Downstream 100 bases:

>100_bases
TACCCCCACTTTGAAAACACCCCGTACAGTTACACCAGTACGGGGTGTTTTTTAGTTAAGCTTGGGTGATCACTTAACCC
AGCTAGAAGGAGTCAACATG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MTDFPTLPSEFIPGDGRFGCGPSKVRPEQIQAIVDGSASVIGTSHRQPAVKNVVGSIREGLSDLFSLPEGYEIILSLGGA
TAFWDAATFGLIEKKSGHLSFGEFSSKFAKASKLAPWLYEPEIVTAETGDAPAPQAFEGADVIAWAHNETSTGAMVPVLR
PEGSEGSLVAIDATSGAGGLPVDIKNSDVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPEFLNLQTAVDNS
LKNQTYNTPAVATLLMLDNQVKWMNSNGGLDGMVARTTASSSALYNWAEAREEASPYVADAAKRSLVVGTIDFDDSIDAA
VIAKILRANGILDTEPYRKLGRNQLRIGMFPAIDSTDVEKLTGAIDFILDGGFAKK

Sequences:

>Translated_376_residues
MTDFPTLPSEFIPGDGRFGCGPSKVRPEQIQAIVDGSASVIGTSHRQPAVKNVVGSIREGLSDLFSLPEGYEIILSLGGA
TAFWDAATFGLIEKKSGHLSFGEFSSKFAKASKLAPWLYEPEIVTAETGDAPAPQAFEGADVIAWAHNETSTGAMVPVLR
PEGSEGSLVAIDATSGAGGLPVDIKNSDVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPEFLNLQTAVDNS
LKNQTYNTPAVATLLMLDNQVKWMNSNGGLDGMVARTTASSSALYNWAEAREEASPYVADAAKRSLVVGTIDFDDSIDAA
VIAKILRANGILDTEPYRKLGRNQLRIGMFPAIDSTDVEKLTGAIDFILDGGFAKK
>Mature_375_residues
TDFPTLPSEFIPGDGRFGCGPSKVRPEQIQAIVDGSASVIGTSHRQPAVKNVVGSIREGLSDLFSLPEGYEIILSLGGAT
AFWDAATFGLIEKKSGHLSFGEFSSKFAKASKLAPWLYEPEIVTAETGDAPAPQAFEGADVIAWAHNETSTGAMVPVLRP
EGSEGSLVAIDATSGAGGLPVDIKNSDVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPEFLNLQTAVDNSL
KNQTYNTPAVATLLMLDNQVKWMNSNGGLDGMVARTTASSSALYNWAEAREEASPYVADAAKRSLVVGTIDFDDSIDAAV
IAKILRANGILDTEPYRKLGRNQLRIGMFPAIDSTDVEKLTGAIDFILDGGFAKK

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily

Homologues:

Organism=Homo sapiens, GI17402893, Length=389, Percent_Identity=22.6221079691517, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356589, Length=361, Percent_Identity=22.9916897506925, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SERC_CORGB (A4QCG9)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001137818.1
- ProteinModelPortal:   A4QCG9
- SMR:   A4QCG9
- STRING:   A4QCG9
- GeneID:   4992177
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_0942
- eggNOG:   COG1932
- HOGENOM:   HBG292317
- OMA:   RIATFPA
- ProtClustDB:   PRK03080
- GO:   GO:0005737
- HAMAP:   MF_00160
- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR006272
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000525
- TIGRFAMs:   TIGR01366

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.52

Molecular weight: Translated: 40050; Mature: 39919

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: BINDING 46-46 BINDING 104-104 BINDING 150-150 BINDING 172-172 BINDING 195-195

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFPTLPSEFIPGDGRFGCGPSKVRPEQIQAIVDGSASVIGTSHRQPAVKNVVGSIREG
CCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
LSDLFSLPEGYEIILSLGGATAFWDAATFGLIEKKSGHLSFGEFSSKFAKASKLAPWLYE
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCEEC
PEIVTAETGDAPAPQAFEGADVIAWAHNETSTGAMVPVLRPEGSEGSLVAIDATSGAGGL
CEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCC
PVDIKNSDVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPEFLNLQTAVDNS
EEEEECCEEEEECCHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LKNQTYNTPAVATLLMLDNQVKWMNSNGGLDGMVARTTASSSALYNWAEAREEASPYVAD
HHCCCCCCHHHHEEEHHCCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHH
AAKRSLVVGTIDFDDSIDAAVIAKILRANGILDTEPYRKLGRNQLRIGMFPAIDSTDVEK
HHCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCHHHH
LTGAIDFILDGGFAKK
HHHHHHEEECCCCCCC
>Mature Secondary Structure 
TDFPTLPSEFIPGDGRFGCGPSKVRPEQIQAIVDGSASVIGTSHRQPAVKNVVGSIREG
CCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
LSDLFSLPEGYEIILSLGGATAFWDAATFGLIEKKSGHLSFGEFSSKFAKASKLAPWLYE
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCEEC
PEIVTAETGDAPAPQAFEGADVIAWAHNETSTGAMVPVLRPEGSEGSLVAIDATSGAGGL
CEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCC
PVDIKNSDVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPEFLNLQTAVDNS
EEEEECCEEEEECCHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LKNQTYNTPAVATLLMLDNQVKWMNSNGGLDGMVARTTASSSALYNWAEAREEASPYVAD
HHCCCCCCHHHHEEEHHCCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHH
AAKRSLVVGTIDFDDSIDAAVIAKILRANGILDTEPYRKLGRNQLRIGMFPAIDSTDVEK
HHCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCHHHH
LTGAIDFILDGGFAKK
HHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA