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The map label for this gene is malF [H]

Identifier: 145294969

GI number: 145294969

Start: 1006408

End: 1007985

Strand: Reverse

Name: malF [H]

Synonym: cgR_0914

Alternate gene names: 145294969

Gene position: 1007985-1006408 (Counterclockwise)

Preceding gene: 145294970

Following gene: 145294968

Centisome position: 30.41

GC content: 65.84

Gene sequence:

>1578_bases
GTGACCACCACACTGGACTCCCGCCCCGTGGCGGATGAGGCGCCGGCCCCGCGGCGTCGTCAAGCAGGAGCCGGTCTGGC
GATCAAGCTCCTCATCATGGCGGCCATCAACGCCTTCGGTTTCTACGGCATCGCCGCCTCCTGGCTCGCCGGGCAGTGGG
GCATACTAGCCTTCCTTGTGGCGGGCCTCATCGGCGCGAACGTTATCTACTTCTGGAACGACCGCCGCACCCGACCTTGG
AAGTACCTCTACCCGGCAGCCGTCATGCTGCTCATCTTCCAGGTGTTCGTGGTGATCTACACCGCGGGCATCGCGTTCAC
CAACTACGGCGACGGGCACAACTCCACCAAGGACCACGCCATCACGGCGATCGAGCTCAAGTACGACGAGCCCGTTCCCG
ACGCCCCGGCCCGCCCCGTCACCGTCATCTCCGGCGACGACGGCCTCGGCCTCGCCGTGCTTGACGACGCCGACCGGGTC
CTCGCCGCCACCACCGGCGAGGAACTGACCCCCGTCGAGGCCACCGTCGAGGACGGACGGATCACCGCCGTCGACGGCTA
CGAGGTCCTCGCCGTGGAGGACGCCATGGCCCGCCAGCAGGAGGTCCTCGACGTCCGCGTGCTGTCCCCGGACGGTGACG
TCGTGCGCACCAACGACGCGCGCACCTCCACCACCTACGTCTCGACGATGCGTTACGACGAGGCGCAGGACGCCATGATC
GCCGCCGACGGCACCGTCTACACCCCCAACGACACCGGCAGTTTCGCCTCCGAGTCCGGCGAGGAACTCCTCCCCGGCTG
GCGCGTCAACGTCGGCCTGTCCAACTTCACGCAGGTCTTCGCCGACTCGACCTACGCCGGCCCCTTCATGAAGGTCACCG
CCTGGACGTTCGTCTTCGCGTTCCTCTCCGTCGCCCTGACCTTCTTCGCCGGCCTGCTCATGGCGCTGCTGTTCAACGAC
CCGAACATGAAGTTCCGCGGCTTCTACCGCGCGCTGGTCATCATGCCGTACGCCTTCCCCGCCTTCCTGTCGATCCTCAT
CTGGGCCGGTCTGCTCAACACCGACTTCGGCTTCTTCAACCAGATCCTCTTCGGCGGCGCGGACATCAACTGGCTCGGCG
ACCCCTGGCTCGCCCGCTTCTCCGCCGTCATGGTCAATCTGTGGCTGGGCTTCCCCTACATGTTCCTCGTCACCACCGGT
GCGCTGCAGTCCATCCCGGACGACGTGTACAAGGCCGCCAAGATCGACGGCGCCGGGGCGTGGACCACGTTCCGGAAGAT
CACCCTCCCGCTGCTCATGGTCGCCGTCGGCCCGCTGCTCGTGGCCAGCTTCGCGATGAACTTCAACAACTTCAACGTGA
TCTACCTGCTCACCGGTGGCGGACCCCGCGATCTCGACTCCCCCACCGGAGTCGGTGCGACGGACATCCTCATCAGCTTC
GTCTACAAGATCGCGTTCGCCTCGGGTGAGAACCAGTACGGCGTCGCCTCCGCCATCTCCCTGATGATCTTCATCATGGT
CGCGGTGGTCGCCGCCATCACCCTCATCCGCTCCAATTCCCTGAAGGAGATTGACTGA

Upstream 100 bases:

>100_bases
ACTTCTGGGGCATCACACAGAACGGCATCGTCAACGGTGCCGACGACCCCGAGCAACTATGGGACACCATGATCACCAAC
ATCGAGAGGGCGATTGAATC

Downstream 100 bases:

>100_bases
TGTCCACACAGGTCACCGACACCGACTTCGAGGTCAACCGCCGCTCTCCCTGGCTGCAGTTCAAGCGGGGCGGATGGCGC
CACATCGTGGCGTGGCTCAT

Product: hypothetical protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MTTTLDSRPVADEAPAPRRRQAGAGLAIKLLIMAAINAFGFYGIAASWLAGQWGILAFLVAGLIGANVIYFWNDRRTRPW
KYLYPAAVMLLIFQVFVVIYTAGIAFTNYGDGHNSTKDHAITAIELKYDEPVPDAPARPVTVISGDDGLGLAVLDDADRV
LAATTGEELTPVEATVEDGRITAVDGYEVLAVEDAMARQQEVLDVRVLSPDGDVVRTNDARTSTTYVSTMRYDEAQDAMI
AADGTVYTPNDTGSFASESGEELLPGWRVNVGLSNFTQVFADSTYAGPFMKVTAWTFVFAFLSVALTFFAGLLMALLFND
PNMKFRGFYRALVIMPYAFPAFLSILIWAGLLNTDFGFFNQILFGGADINWLGDPWLARFSAVMVNLWLGFPYMFLVTTG
ALQSIPDDVYKAAKIDGAGAWTTFRKITLPLLMVAVGPLLVASFAMNFNNFNVIYLLTGGGPRDLDSPTGVGATDILISF
VYKIAFASGENQYGVASAISLMIFIMVAVVAAITLIRSNSLKEID

Sequences:

>Translated_525_residues
MTTTLDSRPVADEAPAPRRRQAGAGLAIKLLIMAAINAFGFYGIAASWLAGQWGILAFLVAGLIGANVIYFWNDRRTRPW
KYLYPAAVMLLIFQVFVVIYTAGIAFTNYGDGHNSTKDHAITAIELKYDEPVPDAPARPVTVISGDDGLGLAVLDDADRV
LAATTGEELTPVEATVEDGRITAVDGYEVLAVEDAMARQQEVLDVRVLSPDGDVVRTNDARTSTTYVSTMRYDEAQDAMI
AADGTVYTPNDTGSFASESGEELLPGWRVNVGLSNFTQVFADSTYAGPFMKVTAWTFVFAFLSVALTFFAGLLMALLFND
PNMKFRGFYRALVIMPYAFPAFLSILIWAGLLNTDFGFFNQILFGGADINWLGDPWLARFSAVMVNLWLGFPYMFLVTTG
ALQSIPDDVYKAAKIDGAGAWTTFRKITLPLLMVAVGPLLVASFAMNFNNFNVIYLLTGGGPRDLDSPTGVGATDILISF
VYKIAFASGENQYGVASAISLMIFIMVAVVAAITLIRSNSLKEID
>Mature_524_residues
TTTLDSRPVADEAPAPRRRQAGAGLAIKLLIMAAINAFGFYGIAASWLAGQWGILAFLVAGLIGANVIYFWNDRRTRPWK
YLYPAAVMLLIFQVFVVIYTAGIAFTNYGDGHNSTKDHAITAIELKYDEPVPDAPARPVTVISGDDGLGLAVLDDADRVL
AATTGEELTPVEATVEDGRITAVDGYEVLAVEDAMARQQEVLDVRVLSPDGDVVRTNDARTSTTYVSTMRYDEAQDAMIA
ADGTVYTPNDTGSFASESGEELLPGWRVNVGLSNFTQVFADSTYAGPFMKVTAWTFVFAFLSVALTFFAGLLMALLFNDP
NMKFRGFYRALVIMPYAFPAFLSILIWAGLLNTDFGFFNQILFGGADINWLGDPWLARFSAVMVNLWLGFPYMFLVTTGA
LQSIPDDVYKAAKIDGAGAWTTFRKITLPLLMVAVGPLLVASFAMNFNNFNVIYLLTGGGPRDLDSPTGVGATDILISFV
YKIAFASGENQYGVASAISLMIFIMVAVVAAITLIRSNSLKEID

Specific function: Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790465, Length=457, Percent_Identity=34.5733041575492, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1787570, Length=255, Percent_Identity=30.9803921568627, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789861, Length=254, Percent_Identity=31.8897637795276, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 56950; Mature: 56819

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTLDSRPVADEAPAPRRRQAGAGLAIKLLIMAAINAFGFYGIAASWLAGQWGILAFLV
CCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGLIGANVIYFWNDRRTRPWKYLYPAAVMLLIFQVFVVIYTAGIAFTNYGDGHNSTKDHA
HHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCE
ITAIELKYDEPVPDAPARPVTVISGDDGLGLAVLDDADRVLAATTGEELTPVEATVEDGR
EEEEEEEECCCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEECCCCCCCCCEEEECCCE
ITAVDGYEVLAVEDAMARQQEVLDVRVLSPDGDVVRTNDARTSTTYVSTMRYDEAQDAMI
EEEECCEEEEEEHHHHHHHHHCEEEEEECCCCCEEECCCCCCCHHEEEEEECCCCCCCEE
AADGTVYTPNDTGSFASESGEELLPGWRVNVGLSNFTQVFADSTYAGPFMKVTAWTFVFA
EECCEEECCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FLSVALTFFAGLLMALLFNDPNMKFRGFYRALVIMPYAFPAFLSILIWAGLLNTDFGFFN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QILFGGADINWLGDPWLARFSAVMVNLWLGFPYMFLVTTGALQSIPDDVYKAAKIDGAGA
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCH
WTTFRKITLPLLMVAVGPLLVASFAMNFNNFNVIYLLTGGGPRDLDSPTGVGATDILISF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHH
VYKIAFASGENQYGVASAISLMIFIMVAVVAAITLIRSNSLKEID
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTTLDSRPVADEAPAPRRRQAGAGLAIKLLIMAAINAFGFYGIAASWLAGQWGILAFLV
CCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGLIGANVIYFWNDRRTRPWKYLYPAAVMLLIFQVFVVIYTAGIAFTNYGDGHNSTKDHA
HHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCE
ITAIELKYDEPVPDAPARPVTVISGDDGLGLAVLDDADRVLAATTGEELTPVEATVEDGR
EEEEEEEECCCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEECCCCCCCCCEEEECCCE
ITAVDGYEVLAVEDAMARQQEVLDVRVLSPDGDVVRTNDARTSTTYVSTMRYDEAQDAMI
EEEECCEEEEEEHHHHHHHHHCEEEEEECCCCCEEECCCCCCCHHEEEEEECCCCCCCEE
AADGTVYTPNDTGSFASESGEELLPGWRVNVGLSNFTQVFADSTYAGPFMKVTAWTFVFA
EECCEEECCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FLSVALTFFAGLLMALLFNDPNMKFRGFYRALVIMPYAFPAFLSILIWAGLLNTDFGFFN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QILFGGADINWLGDPWLARFSAVMVNLWLGFPYMFLVTTGALQSIPDDVYKAAKIDGAGA
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCH
WTTFRKITLPLLMVAVGPLLVASFAMNFNNFNVIYLLTGGGPRDLDSPTGVGATDILISF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHH
VYKIAFASGENQYGVASAISLMIFIMVAVVAAITLIRSNSLKEID
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]