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The map label for this gene is cmtR [H]

Identifier: 145294182

GI number: 145294182

Start: 156396

End: 156719

Strand: Reverse

Name: cmtR [H]

Synonym: cgR_0139

Alternate gene names: 145294182

Gene position: 156719-156396 (Counterclockwise)

Preceding gene: 145294183

Following gene: 145294181

Centisome position: 4.73

GC content: 59.57

Gene sequence:

>324_bases
GTGACGGTCACCCATACCTCGGCGTTGTCCCGGATTGGGCATGCCCTCTACGATGACACCCGGATGGCAATCTTGTTGGC
CCTGCGCAATGGAGCGGCGAGGCCATCGGAATTGGCACAGCAATTGGGCGTCTCCAAGCAAGTGATGTCGAACCAATTGT
CCTGCCTGCGTGGATGCGGTCTAGTCACCTCGACCCCTGAGGGACGACACGTCTGGTACACGCTGGCCGATCCACGTTTG
CGCGATGCATTGGGAGATCTACTCATCCCGGTGCTCACCATCGACCCGGATTGTTGCTCACCTGAGGGATGCACCTGCGC
ATGA

Upstream 100 bases:

>100_bases
TTTCCTACGAGGATGATGGCCCCGATAAGTTCGAACGGCTCCACGGAACCCGTTGAAAAACAGTACAGAGAATTGTGTAC
TATCTACGGTTATACATACG

Downstream 100 bases:

>100_bases
TCTCGCCGACCCTTGACTCCCCGAAATAGATCGGAACTTCCATGATCACCCCCTCTTCCGCGAATTCACACAGAGCCAAG
ATCATCGTGTGGACGGTTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MTVTHTSALSRIGHALYDDTRMAILLALRNGAARPSELAQQLGVSKQVMSNQLSCLRGCGLVTSTPEGRHVWYTLADPRL
RDALGDLLIPVLTIDPDCCSPEGCTCA

Sequences:

>Translated_107_residues
MTVTHTSALSRIGHALYDDTRMAILLALRNGAARPSELAQQLGVSKQVMSNQLSCLRGCGLVTSTPEGRHVWYTLADPRL
RDALGDLLIPVLTIDPDCCSPEGCTCA
>Mature_106_residues
TVTHTSALSRIGHALYDDTRMAILLALRNGAARPSELAQQLGVSKQVMSNQLSCLRGCGLVTSTPEGRHVWYTLADPRLR
DALGDLLIPVLTIDPDCCSPEGCTCA

Specific function: Metal-responsive transcriptional repressor for the cmt operon. Binding of cadmium or lead causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11480; Mature: 11349

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTHTSALSRIGHALYDDTRMAILLALRNGAARPSELAQQLGVSKQVMSNQLSCLRGCG
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCC
LVTSTPEGRHVWYTLADPRLRDALGDLLIPVLTIDPDCCSPEGCTCA
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHEECCCCCCCCCCCCC
>Mature Secondary Structure 
TVTHTSALSRIGHALYDDTRMAILLALRNGAARPSELAQQLGVSKQVMSNQLSCLRGCG
CCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCC
LVTSTPEGRHVWYTLADPRLRDALGDLLIPVLTIDPDCCSPEGCTCA
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]