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The map label for this gene is htpG [H]

Identifier: 145294154

GI number: 145294154

Start: 128828

End: 130654

Strand: Reverse

Name: htpG [H]

Synonym: cgR_0112

Alternate gene names: 145294154

Gene position: 130654-128828 (Counterclockwise)

Preceding gene: 145294156

Following gene: 145294153

Centisome position: 3.94

GC content: 54.68

Gene sequence:

>1827_bases
ATGCAAGAATCCTCACGTGATAATTTCCAAGTTGACCTCGGCGGCGTTGTTGATCTTTTGAGTCGCCACATTTATTCCGG
TCCGAGGGTGTATGTGCGTGAGTTGCTGCAGAATGCGGTTGATGCTTGTACTGCACGTTCTGAACAGGGTGAGGAGGGCT
ACGAGCCGAGTATTCGTATTCGGCCGGTGACCAAGGATCGTGCCACGTTTTCACTGGTTGATAATGGTACGGGCCTGACC
GCGCAGGAGGCGCGGGAATTGCTGGCGACGGTGGGACGGACGTCGAAACGCGATGAATTCGGTCTGCAGCGGGAAGGTCG
CCTGGGGCAATTTGGCATCGGGCTGCTTAGTTGTTTCATGGTGGCGGATGAGATCACCATGGTGTCGCATGCGGAGGGTG
CGTCGGCGATTCGGTGGACTGGTCATGCGGATGGCACGTTTAACCTGGAGATTCTTGGGGATGACGCAACCGATGTCATT
CCGGTGGGCACGACTGTGCACCTGACACCGCGCCCTGATGAGCGCACGTTGCTGACGGAAAATTCCGTGGTCACCATTGC
TAGTAATTATGGCCGCTACCTGCCGATTCCTATTGTGGTGCAGGGTGAGAAAAACACCACCATCACTACATCGCCGGTGT
TTGCAAAGGATACTGATCAGCAGCACAGGCTGTATGCCGGCCGGGAGCGCCTTGGTAAAACTCCTTTTGATGTCATCGAT
CTCACTGGCCCTGGCATCGAGGGTGTGGCTTATGTATTGCCGGAGGCTCAGGCTCCGCATATGTCCAGGCGTCACAGTAT
TTATGTCAACCGCATGTTGGTCTCTGATGGGCCTTCCACGGTGCTGCCCAACTGGGCGTTCTTTGTGGAATGTGAAATCA
ATTCAACCGATTTGGAACCCACCGCATCGCGTGAAGCGCTCATGGATGACACCGCGTTCGCGGCAACCAGGGAACATATC
GGTGAGTGCATTAAATCGTGGCTGATTAACCTCGCCATGACCAAGCCTCACCGCGTGCGGGAATTTACTGCGATTCATGA
TCTTGCCCTGCGCGAGCTGTGCCTATCGGACGCGGACCTGGCTGAAACCATGTTGGGTCTTCTCACCTTGGAGACCTCCC
GTGGTCGCATCTCGATCGGTGAGATCACCACGTTGTCCATCACCGAGGATGTATCGCTGCAGTTGGCCACCACGTTGGAT
GATTTCAGGCAGCTCAACACCATTGCACGCCCCGATACCTTAATTATTAATGGCGGCTACATTCACGACAGCGACCTGGC
TAGGCTCATTCCAGTTCACTACCCTCCGCTGACGGTATCTACCGCTGACCTGCGCGAATCCATGGATCTGATGGAGCTTC
CGCCGCTGCAGGATGTAGAAAAAGCCAAGGCACTGGATGCACAAGTCACGGACTCGCTGAAGGATTTCCAGATCAAGGGC
GCAACGAGAGTTTTTGACCCCGCGGATGTTCCTGCCGTGGTGATTATTGATTCTAAGGCGCAGGCCTCACGGGATCGCAA
TGAAACACAAAGTGCCACCACTGATCGTTGGGCTGACATTTTGGCAACGGTGGATAACACGTTGAGCCGTCAAACAGCCA
ACATTCCACAAGATCAGGGACTATCCGCGTTGTGCTTGAATTGGAACAATTCGCTGGTAAGGAAATTGGCCTCCACTGAT
GACACCGCCGTGGTGTCGCGCACGGTGCGTCTGCTCTACGTGCAGGCGTTGCTGTCCAGCAAAAGGCCACTGCGGGTGAA
GGAACGCACGCTGCTTAATGATTCGCTGGCAGATCTGGTTTCTTTGTCTTTGTCATCCGATATCTAA

Upstream 100 bases:

>100_bases
CGCGATTGCGTCATCGATCGTTGTTGCTTCCATGCGCACCACACTATCTTTCTGCACGCCCTGATGCCCTGTGGATTCAA
AACTGTGCTTTTATAGGCGT

Downstream 100 bases:

>100_bases
GGCAATCCTCCGCTACTCTCGAGGGCATGGATTATGCCTTTGAGCAGTCGGCGACTGCGCTACTAGATCGTGCAATTGAT
ATGCCCATGAACGATGAGCA

Product: HSP90 family protein

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MQESSRDNFQVDLGGVVDLLSRHIYSGPRVYVRELLQNAVDACTARSEQGEEGYEPSIRIRPVTKDRATFSLVDNGTGLT
AQEARELLATVGRTSKRDEFGLQREGRLGQFGIGLLSCFMVADEITMVSHAEGASAIRWTGHADGTFNLEILGDDATDVI
PVGTTVHLTPRPDERTLLTENSVVTIASNYGRYLPIPIVVQGEKNTTITTSPVFAKDTDQQHRLYAGRERLGKTPFDVID
LTGPGIEGVAYVLPEAQAPHMSRRHSIYVNRMLVSDGPSTVLPNWAFFVECEINSTDLEPTASREALMDDTAFAATREHI
GECIKSWLINLAMTKPHRVREFTAIHDLALRELCLSDADLAETMLGLLTLETSRGRISIGEITTLSITEDVSLQLATTLD
DFRQLNTIARPDTLIINGGYIHDSDLARLIPVHYPPLTVSTADLRESMDLMELPPLQDVEKAKALDAQVTDSLKDFQIKG
ATRVFDPADVPAVVIIDSKAQASRDRNETQSATTDRWADILATVDNTLSRQTANIPQDQGLSALCLNWNNSLVRKLASTD
DTAVVSRTVRLLYVQALLSSKRPLRVKERTLLNDSLADLVSLSLSSDI

Sequences:

>Translated_608_residues
MQESSRDNFQVDLGGVVDLLSRHIYSGPRVYVRELLQNAVDACTARSEQGEEGYEPSIRIRPVTKDRATFSLVDNGTGLT
AQEARELLATVGRTSKRDEFGLQREGRLGQFGIGLLSCFMVADEITMVSHAEGASAIRWTGHADGTFNLEILGDDATDVI
PVGTTVHLTPRPDERTLLTENSVVTIASNYGRYLPIPIVVQGEKNTTITTSPVFAKDTDQQHRLYAGRERLGKTPFDVID
LTGPGIEGVAYVLPEAQAPHMSRRHSIYVNRMLVSDGPSTVLPNWAFFVECEINSTDLEPTASREALMDDTAFAATREHI
GECIKSWLINLAMTKPHRVREFTAIHDLALRELCLSDADLAETMLGLLTLETSRGRISIGEITTLSITEDVSLQLATTLD
DFRQLNTIARPDTLIINGGYIHDSDLARLIPVHYPPLTVSTADLRESMDLMELPPLQDVEKAKALDAQVTDSLKDFQIKG
ATRVFDPADVPAVVIIDSKAQASRDRNETQSATTDRWADILATVDNTLSRQTANIPQDQGLSALCLNWNNSLVRKLASTD
DTAVVSRTVRLLYVQALLSSKRPLRVKERTLLNDSLADLVSLSLSSDI
>Mature_608_residues
MQESSRDNFQVDLGGVVDLLSRHIYSGPRVYVRELLQNAVDACTARSEQGEEGYEPSIRIRPVTKDRATFSLVDNGTGLT
AQEARELLATVGRTSKRDEFGLQREGRLGQFGIGLLSCFMVADEITMVSHAEGASAIRWTGHADGTFNLEILGDDATDVI
PVGTTVHLTPRPDERTLLTENSVVTIASNYGRYLPIPIVVQGEKNTTITTSPVFAKDTDQQHRLYAGRERLGKTPFDVID
LTGPGIEGVAYVLPEAQAPHMSRRHSIYVNRMLVSDGPSTVLPNWAFFVECEINSTDLEPTASREALMDDTAFAATREHI
GECIKSWLINLAMTKPHRVREFTAIHDLALRELCLSDADLAETMLGLLTLETSRGRISIGEITTLSITEDVSLQLATTLD
DFRQLNTIARPDTLIINGGYIHDSDLARLIPVHYPPLTVSTADLRESMDLMELPPLQDVEKAKALDAQVTDSLKDFQIKG
ATRVFDPADVPAVVIIDSKAQASRDRNETQSATTDRWADILATVDNTLSRQTANIPQDQGLSALCLNWNNSLVRKLASTD
DTAVVSRTVRLLYVQALLSSKRPLRVKERTLLNDSLADLVSLSLSSDI

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=409, Percent_Identity=24.6943765281174, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI154146191, Length=214, Percent_Identity=25.2336448598131, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI153792590, Length=214, Percent_Identity=25.2336448598131, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI20149594, Length=207, Percent_Identity=27.0531400966184, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4507677, Length=220, Percent_Identity=23.6363636363636, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1786679, Length=640, Percent_Identity=23.75, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115535205, Length=415, Percent_Identity=25.3012048192771, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI115535167, Length=415, Percent_Identity=25.3012048192771, Blast_Score=125, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17559162, Length=201, Percent_Identity=25.8706467661692, Blast_Score=85, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325016, Length=207, Percent_Identity=26.0869565217391, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323840, Length=200, Percent_Identity=26, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24586016, Length=424, Percent_Identity=26.4150943396226, Blast_Score=119, Evalue=8e-27,
Organism=Drosophila melanogaster, GI17647529, Length=214, Percent_Identity=25.2336448598131, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357739, Length=220, Percent_Identity=23.6363636363636, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 66891; Mature: 66891

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQESSRDNFQVDLGGVVDLLSRHIYSGPRVYVRELLQNAVDACTARSEQGEEGYEPSIRI
CCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
RPVTKDRATFSLVDNGTGLTAQEARELLATVGRTSKRDEFGLQREGRLGQFGIGLLSCFM
EECCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHH
VADEITMVSHAEGASAIRWTGHADGTFNLEILGDDATDVIPVGTTVHLTPRPDERTLLTE
HHHHHHEEECCCCCCEEEECCCCCCEEEEEEECCCCCCEEECCCEEEECCCCCCCEEEEC
NSVVTIASNYGRYLPIPIVVQGEKNTTITTSPVFAKDTDQQHRLYAGRERLGKTPFDVID
CCEEEEECCCCCEECEEEEEECCCCCEEEECCCEECCCCCHHHHHHHHHHHCCCCCEEEE
LTGPGIEGVAYVLPEAQAPHMSRRHSIYVNRMLVSDGPSTVLPNWAFFVECEINSTDLEP
CCCCCCCCEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCC
TASREALMDDTAFAATREHIGECIKSWLINLAMTKPHRVREFTAIHDLALRELCLSDADL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHH
AETMLGLLTLETSRGRISIGEITTLSITEDVSLQLATTLDDFRQLNTIARPDTLIINGGY
HHHHHHHHEEECCCCEEEECCEEEEEEECCCCEEEEHHHHHHHHHHHCCCCCEEEEECCE
IHDSDLARLIPVHYPPLTVSTADLRESMDLMELPPLQDVEKAKALDAQVTDSLKDFQIKG
EECCCHHHCCCCCCCCCEEEHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHCHHHEEECC
ATRVFDPADVPAVVIIDSKAQASRDRNETQSATTDRWADILATVDNTLSRQTANIPQDQG
CCEECCCCCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LSALCLNWNNSLVRKLASTDDTAVVSRTVRLLYVQALLSSKRPLRVKERTLLNDSLADLV
CEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SLSLSSDI
HHHHCCCC
>Mature Secondary Structure
MQESSRDNFQVDLGGVVDLLSRHIYSGPRVYVRELLQNAVDACTARSEQGEEGYEPSIRI
CCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
RPVTKDRATFSLVDNGTGLTAQEARELLATVGRTSKRDEFGLQREGRLGQFGIGLLSCFM
EECCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHH
VADEITMVSHAEGASAIRWTGHADGTFNLEILGDDATDVIPVGTTVHLTPRPDERTLLTE
HHHHHHEEECCCCCCEEEECCCCCCEEEEEEECCCCCCEEECCCEEEECCCCCCCEEEEC
NSVVTIASNYGRYLPIPIVVQGEKNTTITTSPVFAKDTDQQHRLYAGRERLGKTPFDVID
CCEEEEECCCCCEECEEEEEECCCCCEEEECCCEECCCCCHHHHHHHHHHHCCCCCEEEE
LTGPGIEGVAYVLPEAQAPHMSRRHSIYVNRMLVSDGPSTVLPNWAFFVECEINSTDLEP
CCCCCCCCEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCC
TASREALMDDTAFAATREHIGECIKSWLINLAMTKPHRVREFTAIHDLALRELCLSDADL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHH
AETMLGLLTLETSRGRISIGEITTLSITEDVSLQLATTLDDFRQLNTIARPDTLIINGGY
HHHHHHHHEEECCCCEEEECCEEEEEEECCCCEEEEHHHHHHHHHHHCCCCCEEEEECCE
IHDSDLARLIPVHYPPLTVSTADLRESMDLMELPPLQDVEKAKALDAQVTDSLKDFQIKG
EECCCHHHCCCCCCCCCEEEHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHCHHHEEECC
ATRVFDPADVPAVVIIDSKAQASRDRNETQSATTDRWADILATVDNTLSRQTANIPQDQG
CCEECCCCCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LSALCLNWNNSLVRKLASTDDTAVVSRTVRLLYVQALLSSKRPLRVKERTLLNDSLADLV
CEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SLSLSSDI
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA