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The map label for this gene is clcB [H]

Identifier: 145294124

GI number: 145294124

Start: 92847

End: 94118

Strand: Direct

Name: clcB [H]

Synonym: cgR_0082

Alternate gene names: 145294124

Gene position: 92847-94118 (Clockwise)

Preceding gene: 145294121

Following gene: 145294126

Centisome position: 2.8

GC content: 59.36

Gene sequence:

>1272_bases
GTGTCAACCATTCCGCTGAATCGTCTAGCCGTTATCGCTGCCATCATTGGTGTCGGTACCGGGCTGTTTGTTGCTGCACT
GAACTGGTCTGCCATTGGCGTGGAGCGTTTAGTTTATGGCGCTGACCATTTGCATAATCACAATCCGGTGGCCAATGTGT
CGCCACTTCGCCTGTCCATCACGGTGATTGTGCTTAGCGTGGTGGCCTCCTGGGCGTGGTTTTTTGTGCACCGCACGGGG
TCGAAAGAGGTCTCGATTGTGGGTGCGATCCGGGGCGAGAAGATGCCGATTTTGGAGACCATCGCGTCCGCATTTTTGCA
GGTCACCACGGTTGCTGCGGGTGCGCCGGTGGGTGCAGAGAACGCTCCACGTATTGCTGGAGCCTTGGTGGGAGAGCGGT
TTAGTCGGTGGTTGCAGCTCGATATTGATGCAAAGCGCATTTTGGTGGCCTCCGCCGCGGGAGCTGGTTTGGGAGCAAGC
TTCCACCTTCCCCTGGCAGGCGTGCTGTTTGCCCTTGAGGTCCTACTGGTTGAGGCCTCCACTCGGACCGTGGTCATCGC
AATTATCACCACGACCGCCGCCGTTGCCACCACTGGATTTTTCGTGCAAACCCCAGATGTGTTCAGCACTGTCCCGCTGA
CGGAAAGCCCATGGATGCTGCTTGCCGCGATGGTTACCGGTGTGGTTGCTGGCATGTGCGGGCACTGGTTTTCAGCGGCG
GCGCACAAAATGGCGCAGGCCTCGCCCAAGGGTGTGAGGATTTTGTGGCAGATGCCGTTGGGTTTCGTGGTGATCGCTGC
GGTGATTTATTTCTTCCCCGAAACCCTGGCGAATCCCCGTTGGCTTGCCGATTCCATGCTCGGCGATGGCCTGATCCTCA
GCACCATTTTATTGGTACTCGTGCTGCGCACCGCCATGTTTTTGCTCGCCTTCCGCGTGGGCATGGTCGGCGGTAACCTG
ATCCCCGCGTTCGCACTCGGATCCATGGTCGGTGGGGTAGTGGGTGCTGTATTGGAACCCATCACTAACGTCCCGATCGC
CGCTTTTGCGCTGCTTGGCGCCGCCGCATTTTTGTCCACCACCATGGCAGCGCCACTGTTCGGGCTCATCGCCGCAGTGG
AATTCACCGACATGGAAGCCCAAGGCTACCTCCCGATTTTCCTCGCGGTAGCCTCCGCGGTCCTCGCGGTGCGCGTGTGG
TCTGTCATCGCCAAGCGGGAGCTCCGCGCCATCCCGATCACGTACGCGAGCTGGACGGGCGAGCTTAAATAA

Upstream 100 bases:

>100_bases
CCTTCATCATAGTTTTAAATCTGGGGCAGAGGCGGGAATTTAAACACCTCTGATACAGCGTTTACTGGCTATAGTGTTGC
CCGTGCCAAATCGAGTTCCT

Downstream 100 bases:

>100_bases
GCTTGTCGACGCCTCCCTCCACCTTCCATTTAGTAAACGCTTTTCAGACTGTCACAGACTCTTGAGCTTCCAGCGCACGA
GCTTTGTCTGTTTTCTGCAC

Product: hypothetical protein

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSTIPLNRLAVIAAIIGVGTGLFVAALNWSAIGVERLVYGADHLHNHNPVANVSPLRLSITVIVLSVVASWAWFFVHRTG
SKEVSIVGAIRGEKMPILETIASAFLQVTTVAAGAPVGAENAPRIAGALVGERFSRWLQLDIDAKRILVASAAGAGLGAS
FHLPLAGVLFALEVLLVEASTRTVVIAIITTTAAVATTGFFVQTPDVFSTVPLTESPWMLLAAMVTGVVAGMCGHWFSAA
AHKMAQASPKGVRILWQMPLGFVVIAAVIYFFPETLANPRWLADSMLGDGLILSTILLVLVLRTAMFLLAFRVGMVGGNL
IPAFALGSMVGGVVGAVLEPITNVPIAAFALLGAAAFLSTTMAAPLFGLIAAVEFTDMEAQGYLPIFLAVASAVLAVRVW
SVIAKRELRAIPITYASWTGELK

Sequences:

>Translated_423_residues
MSTIPLNRLAVIAAIIGVGTGLFVAALNWSAIGVERLVYGADHLHNHNPVANVSPLRLSITVIVLSVVASWAWFFVHRTG
SKEVSIVGAIRGEKMPILETIASAFLQVTTVAAGAPVGAENAPRIAGALVGERFSRWLQLDIDAKRILVASAAGAGLGAS
FHLPLAGVLFALEVLLVEASTRTVVIAIITTTAAVATTGFFVQTPDVFSTVPLTESPWMLLAAMVTGVVAGMCGHWFSAA
AHKMAQASPKGVRILWQMPLGFVVIAAVIYFFPETLANPRWLADSMLGDGLILSTILLVLVLRTAMFLLAFRVGMVGGNL
IPAFALGSMVGGVVGAVLEPITNVPIAAFALLGAAAFLSTTMAAPLFGLIAAVEFTDMEAQGYLPIFLAVASAVLAVRVW
SVIAKRELRAIPITYASWTGELK
>Mature_422_residues
STIPLNRLAVIAAIIGVGTGLFVAALNWSAIGVERLVYGADHLHNHNPVANVSPLRLSITVIVLSVVASWAWFFVHRTGS
KEVSIVGAIRGEKMPILETIASAFLQVTTVAAGAPVGAENAPRIAGALVGERFSRWLQLDIDAKRILVASAAGAGLGASF
HLPLAGVLFALEVLLVEASTRTVVIAIITTTAAVATTGFFVQTPDVFSTVPLTESPWMLLAAMVTGVVAGMCGHWFSAAA
HKMAQASPKGVRILWQMPLGFVVIAAVIYFFPETLANPRWLADSMLGDGLILSTILLVLVLRTAMFLLAFRVGMVGGNLI
PAFALGSMVGGVVGAVLEPITNVPIAAFALLGAAAFLSTTMAAPLFGLIAAVEFTDMEAQGYLPIFLAVASAVLAVRVWS
VIAKRELRAIPITYASWTGELK

Specific function: Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response [H]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 44345; Mature: 44214

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS00334 MYB_2 ; PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIPLNRLAVIAAIIGVGTGLFVAALNWSAIGVERLVYGADHLHNHNPVANVSPLRLSI
CCCCCHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
TVIVLSVVASWAWFFVHRTGSKEVSIVGAIRGEKMPILETIASAFLQVTTVAAGAPVGAE
HHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
NAPRIAGALVGERFSRWLQLDIDAKRILVASAAGAGLGASFHLPLAGVLFALEVLLVEAS
CCCHHHHHHHHHHHHHHEEECCCHHEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHCCC
TRTVVIAIITTTAAVATTGFFVQTPDVFSTVPLTESPWMLLAAMVTGVVAGMCGHWFSAA
CCEEEEEEEHHHHHHHHCCCEEECCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AHKMAQASPKGVRILWQMPLGFVVIAAVIYFFPETLANPRWLADSMLGDGLILSTILLVL
HHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHH
VLRTAMFLLAFRVGMVGGNLIPAFALGSMVGGVVGAVLEPITNVPIAAFALLGAAAFLST
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TMAAPLFGLIAAVEFTDMEAQGYLPIFLAVASAVLAVRVWSVIAKRELRAIPITYASWTG
HHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
ELK
CCC
>Mature Secondary Structure 
STIPLNRLAVIAAIIGVGTGLFVAALNWSAIGVERLVYGADHLHNHNPVANVSPLRLSI
CCCCHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
TVIVLSVVASWAWFFVHRTGSKEVSIVGAIRGEKMPILETIASAFLQVTTVAAGAPVGAE
HHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
NAPRIAGALVGERFSRWLQLDIDAKRILVASAAGAGLGASFHLPLAGVLFALEVLLVEAS
CCCHHHHHHHHHHHHHHEEECCCHHEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHCCC
TRTVVIAIITTTAAVATTGFFVQTPDVFSTVPLTESPWMLLAAMVTGVVAGMCGHWFSAA
CCEEEEEEEHHHHHHHHCCCEEECCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AHKMAQASPKGVRILWQMPLGFVVIAAVIYFFPETLANPRWLADSMLGDGLILSTILLVL
HHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHH
VLRTAMFLLAFRVGMVGGNLIPAFALGSMVGGVVGAVLEPITNVPIAAFALLGAAAFLST
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TMAAPLFGLIAAVEFTDMEAQGYLPIFLAVASAVLAVRVWSVIAKRELRAIPITYASWTG
HHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
ELK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA