Click here to switch to the map view.

The map label for this gene is oxaA1 [H]

Identifier: 138897069

GI number: 138897069

Start: 3548635

End: 3549351

Strand: Reverse

Name: oxaA1 [H]

Synonym: GTNG_3442

Alternate gene names: 138897069

Gene position: 3549351-3548635 (Counterclockwise)

Preceding gene: 138897070

Following gene: 138897068

Centisome position: 99.97

GC content: 45.33

Gene sequence:

>717_bases
ATGCTGTCCGGATGCACGGAAATTAATGAACCGATCACCCAAGAAAGCAAGGGATTTTGGAACGAATATATCGTTTATCC
GCTTTCTTGGCTTATTAAATATGTCGCTGAGTTGCTTGGCGGAAGCTTCGGGTTATCGATCATTGTCGTTACCATTCTCA
TCCGTCTGCTCATTTTGCCGCTGATGATTCAACAGACGCGCAATGCGAAAGCGATGCAAGCGCTTCAGCCTGAAATTGAG
GCGTTGCGCAAAAAATACAGTTCCAAAGACGCGCAAACCCAGCAAAAGCTCCAGCAAGAGATGATGTTATTGTTCCAAAA
GCACGGCGTCAACCCGATGGCTGGCTGCTTCCCGATTTTAATTCAAATGCCGATTTTAATCGGTTTCTACCATGCTATTA
TGCGCACAAGGGAAATCGCTCAACATAACTTTTTATGGTTCGACCTTGGTGACAAGGACCCATACTATATTTTGCCTTTA
GTTGCCGGATTGACGACGTTCATCCAGCAAAAAATTATGATGGCCGGCTCTGCTCAGCAAAATCCACAAATGGCGATGAT
GCTTTGGATGATGCCGATTATGATTGTCATTTTTGCGATCAACTTCCCAGCCGCCTTGTCGCTTTACTGGGTTGTCGGAA
ATATTTTCTCCATTGTGCAAACGTATCTCATTAAAGGGCCCGCTGTTTCTGCCCATTCAGGAGGAGCGAAAAAGTGA

Upstream 100 bases:

>100_bases
AAAAGGTGGTAAAATACATACGTGAACTTGTACATGTGGGAGGAAAAAGAAGGTGAAAAGGCGAATTCCATTGATTGTTT
TGCTTAGTGCATTGGCTGCC

Downstream 100 bases:

>100_bases
AAGAAGTAACCGCGACTGCCGCAACAGTCGAAGAAGCGGTGGAGTTGGCGCTCGCACAGCTCGGTGTGCCTCGGGAGCGC
GCGAATATCGTCGTAATCGA

Product: OxaA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MLSGCTEINEPITQESKGFWNEYIVYPLSWLIKYVAELLGGSFGLSIIVVTILIRLLILPLMIQQTRNAKAMQALQPEIE
ALRKKYSSKDAQTQQKLQQEMMLLFQKHGVNPMAGCFPILIQMPILIGFYHAIMRTREIAQHNFLWFDLGDKDPYYILPL
VAGLTTFIQQKIMMAGSAQQNPQMAMMLWMMPIMIVIFAINFPAALSLYWVVGNIFSIVQTYLIKGPAVSAHSGGAKK

Sequences:

>Translated_238_residues
MLSGCTEINEPITQESKGFWNEYIVYPLSWLIKYVAELLGGSFGLSIIVVTILIRLLILPLMIQQTRNAKAMQALQPEIE
ALRKKYSSKDAQTQQKLQQEMMLLFQKHGVNPMAGCFPILIQMPILIGFYHAIMRTREIAQHNFLWFDLGDKDPYYILPL
VAGLTTFIQQKIMMAGSAQQNPQMAMMLWMMPIMIVIFAINFPAALSLYWVVGNIFSIVQTYLIKGPAVSAHSGGAKK
>Mature_238_residues
MLSGCTEINEPITQESKGFWNEYIVYPLSWLIKYVAELLGGSFGLSIIVVTILIRLLILPLMIQQTRNAKAMQALQPEIE
ALRKKYSSKDAQTQQKLQQEMMLLFQKHGVNPMAGCFPILIQMPILIGFYHAIMRTREIAQHNFLWFDLGDKDPYYILPL
VAGLTTFIQQKIMMAGSAQQNPQMAMMLWMMPIMIVIFAINFPAALSLYWVVGNIFSIVQTYLIKGPAVSAHSGGAKK

Specific function: Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes [H]

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI223718097, Length=218, Percent_Identity=30.2752293577982, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI1790140, Length=207, Percent_Identity=38.1642512077295, Blast_Score=147, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6321002, Length=210, Percent_Identity=27.6190476190476, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24662345, Length=200, Percent_Identity=30.5, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356443, Length=200, Percent_Identity=30.5, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001708
- InterPro:   IPR023060 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 26933; Mature: 26933

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGCTEINEPITQESKGFWNEYIVYPLSWLIKYVAELLGGSFGLSIIVVTILIRLLILP
CCCCCCHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LMIQQTRNAKAMQALQPEIEALRKKYSSKDAQTQQKLQQEMMLLFQKHGVNPMAGCFPIL
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IQMPILIGFYHAIMRTREIAQHNFLWFDLGDKDPYYILPLVAGLTTFIQQKIMMAGSAQQ
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
NPQMAMMLWMMPIMIVIFAINFPAALSLYWVVGNIFSIVQTYLIKGPAVSAHSGGAKK
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSGCTEINEPITQESKGFWNEYIVYPLSWLIKYVAELLGGSFGLSIIVVTILIRLLILP
CCCCCCHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LMIQQTRNAKAMQALQPEIEALRKKYSSKDAQTQQKLQQEMMLLFQKHGVNPMAGCFPIL
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IQMPILIGFYHAIMRTREIAQHNFLWFDLGDKDPYYILPLVAGLTTFIQQKIMMAGSAQQ
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
NPQMAMMLWMMPIMIVIFAINFPAALSLYWVVGNIFSIVQTYLIKGPAVSAHSGGAKK
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]