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The map label for this gene is dnaC [H]

Identifier: 138897046

GI number: 138897046

Start: 3524825

End: 3526189

Strand: Reverse

Name: dnaC [H]

Synonym: GTNG_3417

Alternate gene names: 138897046

Gene position: 3526189-3524825 (Counterclockwise)

Preceding gene: 138897047

Following gene: 138897045

Centisome position: 99.32

GC content: 50.11

Gene sequence:

>1365_bases
ATGAGTGAACTTTTTTCTGAACGAATTCCTCCGCAAAGCATTGAAGCCGAGCAGGCTGTGCTTGGCGCCGTGTTTTTAGA
TCCCACTGCGTTAACGCTCGCTTCGGAAATGTTAATTCCAGAAGATTTTTACCGCGCGGCCCATCAAAAAATTTTCCACG
CCATGCTTCGTGTCGCCGACAAAGGCGAACCGGTTGATTTAGTCACAGTGACAGCGGAACTCGCTGCTTCCGAGCAGCTT
GAAGAGATCGGCGGTGTCTCATATTTAAGCGAGCTCGCCGATGCCGTGCCGACAGCGGCTAACGTTGAATATTACGCCCG
CATCGTGGAAGAAAAATCGGTGCTTCGCCGCCTCATCCGTACGGCGACATCGATCGCCCAGGACGGGTATACAAGGGAAG
ACGAAATCGACCTTCTGCTTGATGAAGCAGAACAAAAAATTATGGAGGTTTCCCAACGGAAACATTCAGGTGCCTTTAAA
AATATTAAGGATATTCTCGTTCAAACGTACGATAATATTGAAATGCTCCATAACCGGAACGGAGAAATTACCGGCATCCC
GACGGGATTTACTGAGCTTGACCGGATGACGTCCGGTTTTCAGCGGAGCGATTTGATCATCGTTGCTGCCCGGCCGTCGG
TCGGGAAAACGGCGTTTGCTTTAAACATCGCGCAGAACGTAGCCACAAAAGCAAACGAAAATGTTGCCATTTTCAGTTTA
GAAATGAGTGCCCAGCAGCTCGTGATGCGGATGCTTTGCGCCGAGGGAAACATCAATGCACAAAACTTGCGCACCGGCCA
ACTGACGCCGGAAGACTGGGGTAAGCTGACGATGGCGATGGGGAGCCTATCGAACGCTGGCATTTATATTGACGATACGC
CGAGCATCCGCGTCAGTGATATTCGCGCCAAATGCCGCCGTCTGAAACAAGAAAGCGGCCTTGGCATGATCGTCATTGAC
TATTTGCAGCTTATCCAAGGAAGCGGACGCAGCAAAGAAAACCGCCAGCAGGAAGTATCGGAAATTTCCCGTTCGTTAAA
GGCGCTCGCCCGCGAGCTCGAAGTGCCAGTCATCGCCTTGTCACAGCTGTCGCGCAGCGTTGAGCAGCGCCAAGACAAGC
GGCCGATGATGTCCGACATTCGTGAATCCGGAAGCATTGAGCAAGACGCTGATATCGTCGCTTTTTTATATCGGGATGAT
TATTACAACAAAGATTCCGAGAACAAAAATATTATCGAGATCATTATCGCGAAACAGCGTAACGGCCCAGTGGGGACGGT
ACAGCTTGCTTTTATTAAAGAGTATAATAAATTTGTGAACTTAGAGCGCCGTTTCGATGAGGCGCAAATTCCGCCAGGAG
CATAA

Upstream 100 bases:

>100_bases
AAATAACGGTGACGGTTCACTCCAAGATGCGAAGATGTCCCCGCCCGCTGCGGCGGGGCTTCCTTGCTTATCGGCTAACA
GGGGAAAAGGTGGTGAGACG

Downstream 100 bases:

>100_bases
AACAGCGCGATGCCAATGGCATCGCCTCTTTTCATGTCTCTGGGTAATAAACGAATAAAATAGTTTATAATTGTTTTTAA
TGTTCGTGTTTCATTGACTT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSELFSERIPPQSIEAEQAVLGAVFLDPTALTLASEMLIPEDFYRAAHQKIFHAMLRVADKGEPVDLVTVTAELAASEQL
EEIGGVSYLSELADAVPTAANVEYYARIVEEKSVLRRLIRTATSIAQDGYTREDEIDLLLDEAEQKIMEVSQRKHSGAFK
NIKDILVQTYDNIEMLHNRNGEITGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNIAQNVATKANENVAIFSL
EMSAQQLVMRMLCAEGNINAQNLRTGQLTPEDWGKLTMAMGSLSNAGIYIDDTPSIRVSDIRAKCRRLKQESGLGMIVID
YLQLIQGSGRSKENRQQEVSEISRSLKALARELEVPVIALSQLSRSVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDD
YYNKDSENKNIIEIIIAKQRNGPVGTVQLAFIKEYNKFVNLERRFDEAQIPPGA

Sequences:

>Translated_454_residues
MSELFSERIPPQSIEAEQAVLGAVFLDPTALTLASEMLIPEDFYRAAHQKIFHAMLRVADKGEPVDLVTVTAELAASEQL
EEIGGVSYLSELADAVPTAANVEYYARIVEEKSVLRRLIRTATSIAQDGYTREDEIDLLLDEAEQKIMEVSQRKHSGAFK
NIKDILVQTYDNIEMLHNRNGEITGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNIAQNVATKANENVAIFSL
EMSAQQLVMRMLCAEGNINAQNLRTGQLTPEDWGKLTMAMGSLSNAGIYIDDTPSIRVSDIRAKCRRLKQESGLGMIVID
YLQLIQGSGRSKENRQQEVSEISRSLKALARELEVPVIALSQLSRSVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDD
YYNKDSENKNIIEIIIAKQRNGPVGTVQLAFIKEYNKFVNLERRFDEAQIPPGA
>Mature_453_residues
SELFSERIPPQSIEAEQAVLGAVFLDPTALTLASEMLIPEDFYRAAHQKIFHAMLRVADKGEPVDLVTVTAELAASEQLE
EIGGVSYLSELADAVPTAANVEYYARIVEEKSVLRRLIRTATSIAQDGYTREDEIDLLLDEAEQKIMEVSQRKHSGAFKN
IKDILVQTYDNIEMLHNRNGEITGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNIAQNVATKANENVAIFSLE
MSAQQLVMRMLCAEGNINAQNLRTGQLTPEDWGKLTMAMGSLSNAGIYIDDTPSIRVSDIRAKCRRLKQESGLGMIVIDY
LQLIQGSGRSKENRQQEVSEISRSLKALARELEVPVIALSQLSRSVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDY
YNKDSENKNIIEIIIAKQRNGPVGTVQLAFIKEYNKFVNLERRFDEAQIPPGA

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=443, Percent_Identity=46.7268623024831, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 50650; Mature: 50519

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELFSERIPPQSIEAEQAVLGAVFLDPTALTLASEMLIPEDFYRAAHQKIFHAMLRVAD
CCCHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
KGEPVDLVTVTAELAASEQLEEIGGVSYLSELADAVPTAANVEYYARIVEEKSVLRRLIR
CCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
TATSIAQDGYTREDEIDLLLDEAEQKIMEVSQRKHSGAFKNIKDILVQTYDNIEMLHNRN
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
GEITGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNIAQNVATKANENVAIFSL
CCEEECCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
EMSAQQLVMRMLCAEGNINAQNLRTGQLTPEDWGKLTMAMGSLSNAGIYIDDTPSIRVSD
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEHHH
IRAKCRRLKQESGLGMIVIDYLQLIQGSGRSKENRQQEVSEISRSLKALARELEVPVIAL
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SQLSRSVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNKDSENKNIIEIIIAKQR
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEECC
NGPVGTVQLAFIKEYNKFVNLERRFDEAQIPPGA
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SELFSERIPPQSIEAEQAVLGAVFLDPTALTLASEMLIPEDFYRAAHQKIFHAMLRVAD
CCHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
KGEPVDLVTVTAELAASEQLEEIGGVSYLSELADAVPTAANVEYYARIVEEKSVLRRLIR
CCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
TATSIAQDGYTREDEIDLLLDEAEQKIMEVSQRKHSGAFKNIKDILVQTYDNIEMLHNRN
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
GEITGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNIAQNVATKANENVAIFSL
CCEEECCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
EMSAQQLVMRMLCAEGNINAQNLRTGQLTPEDWGKLTMAMGSLSNAGIYIDDTPSIRVSD
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEHHH
IRAKCRRLKQESGLGMIVIDYLQLIQGSGRSKENRQQEVSEISRSLKALARELEVPVIAL
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SQLSRSVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNKDSENKNIIEIIIAKQR
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEECC
NGPVGTVQLAFIKEYNKFVNLERRFDEAQIPPGA
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]