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The map label for this gene is pdxA [H]

Identifier: 138896867

GI number: 138896867

Start: 3343597

End: 3344592

Strand: Direct

Name: pdxA [H]

Synonym: GTNG_3232

Alternate gene names: 138896867

Gene position: 3343597-3344592 (Clockwise)

Preceding gene: 138896866

Following gene: 138896869

Centisome position: 94.18

GC content: 52.61

Gene sequence:

>996_bases
ATGAAACCTACCATTGGAATCACGATGGGAGATGCCGCAGGAGTTGGTCCGGAGATTATCGTTAAAGCCCTGCAAAACTC
GTCTATCTACGAACAGTGCCATCCTTTAGTAATCGGGGATGCAAAAATATTGGAACGTGCTGTTCGGATCACAAACGCCG
GCCTGACGGTTCGCCCGATTTCTGACATCGCCGAAGCAGATTACCGATACGGGATGATTGACTGCCTCCATTTAGATTTA
CTCCCGGTCGACTTGCCGTTTGGTCAAGTATCGGCCGCAGCGGGAGATGCCGCTTTCCAATTTTTAAAACGGGCCATTGA
ACTGGCCCAAAACGGGGAAATCGACGCCATTTGCACCGCCCCGCTGAACAAAGAAGCAATGCACAAAGGCGGCCATCTGT
ATCCAGGGCACACAGAAATCTTAGCTGATTTAACCGGCACAGAGGACTATGCGATGATGCTATCTTCACCGCAACTAAAG
GTCATTCATCTCACGACCCACGTCGGGCTCATTCAAGCGATCGAAATGATTAATCCCGAGCGCACCTACAAAGTCATTAA
ACTGGCTCATGATACATTGACAAGAGCGGGGAAGGAACACCCAAGCATCGCCGTATGCGGCATTAACCCCCATGCTGGGG
AAAACGGGCTGTTCGGCAATGGGGAGGAAGAGGAAAAACTAATCCCAGCCATTCACAAAGCCCAAGCAGAAGGAATCAAT
GTCACCGGGCCATACCCTGCTGACACGCTCTTTTACCGAGCCGTACGTGGGGATTTTGACATCGTTGTAGCATGTTACCA
CGACCAAGGGCATGCCCCGATCAAAGTGCTCGGGCTCGAAGCCGGCGTCAACATCACCGTCGGCCTAAAAGGCGGCATCA
TCCGCACCTCAGTCGACCACGGCACCGCTTTCGACATTGCTGGGAAAAACCTAGCCGACGAACGAAGCATGCTTGAAGCC
ATCCGTGTCGCCGTCGAACTAGCGCCGAAACGGTGA

Upstream 100 bases:

>100_bases
TCCATGAGTCGGAAATGTACGTCGTTACCAAGGCTGGAGCCTTTGGTTCAGAAAACACTTTAATTCAAGCCGTTCATCAG
TTACAAGGAGTCGATGCCAA

Downstream 100 bases:

>100_bases
CGGCCAACACCATAGGCGGCAGTCCCCCATTCTTGCCGCCTATGTTTTAAAAATCACTCCGGTCTGCCATCAACCAGCAC
ACTCAGATTAGAAGGATCGC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKPTIGITMGDAAGVGPEIIVKALQNSSIYEQCHPLVIGDAKILERAVRITNAGLTVRPISDIAEADYRYGMIDCLHLDL
LPVDLPFGQVSAAAGDAAFQFLKRAIELAQNGEIDAICTAPLNKEAMHKGGHLYPGHTEILADLTGTEDYAMMLSSPQLK
VIHLTTHVGLIQAIEMINPERTYKVIKLAHDTLTRAGKEHPSIAVCGINPHAGENGLFGNGEEEEKLIPAIHKAQAEGIN
VTGPYPADTLFYRAVRGDFDIVVACYHDQGHAPIKVLGLEAGVNITVGLKGGIIRTSVDHGTAFDIAGKNLADERSMLEA
IRVAVELAPKR

Sequences:

>Translated_331_residues
MKPTIGITMGDAAGVGPEIIVKALQNSSIYEQCHPLVIGDAKILERAVRITNAGLTVRPISDIAEADYRYGMIDCLHLDL
LPVDLPFGQVSAAAGDAAFQFLKRAIELAQNGEIDAICTAPLNKEAMHKGGHLYPGHTEILADLTGTEDYAMMLSSPQLK
VIHLTTHVGLIQAIEMINPERTYKVIKLAHDTLTRAGKEHPSIAVCGINPHAGENGLFGNGEEEEKLIPAIHKAQAEGIN
VTGPYPADTLFYRAVRGDFDIVVACYHDQGHAPIKVLGLEAGVNITVGLKGGIIRTSVDHGTAFDIAGKNLADERSMLEA
IRVAVELAPKR
>Mature_331_residues
MKPTIGITMGDAAGVGPEIIVKALQNSSIYEQCHPLVIGDAKILERAVRITNAGLTVRPISDIAEADYRYGMIDCLHLDL
LPVDLPFGQVSAAAGDAAFQFLKRAIELAQNGEIDAICTAPLNKEAMHKGGHLYPGHTEILADLTGTEDYAMMLSSPQLK
VIHLTTHVGLIQAIEMINPERTYKVIKLAHDTLTRAGKEHPSIAVCGINPHAGENGLFGNGEEEEKLIPAIHKAQAEGIN
VTGPYPADTLFYRAVRGDFDIVVACYHDQGHAPIKVLGLEAGVNITVGLKGGIIRTSVDHGTAFDIAGKNLADERSMLEA
IRVAVELAPKR

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=37.7300613496933, Blast_Score=190, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 35469; Mature: 35469

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTIGITMGDAAGVGPEIIVKALQNSSIYEQCHPLVIGDAKILERAVRITNAGLTVRPI
CCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHCCCEEECCHHHHHHHHHHHCCCEEEEEH
SDIAEADYRYGMIDCLHLDLLPVDLPFGQVSAAAGDAAFQFLKRAIELAQNGEIDAICTA
HHHHHHHCCCCCEEEEEEEEEEECCCCCCHHHHCHHHHHHHHHHHHHHHCCCCEEEEEEC
PLNKEAMHKGGHLYPGHTEILADLTGTEDYAMMLSSPQLKVIHLTTHVGLIQAIEMINPE
CCCHHHHHCCCCCCCCHHHHEEECCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCC
RTYKVIKLAHDTLTRAGKEHPSIAVCGINPHAGENGLFGNGEEEEKLIPAIHKAQAEGIN
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
VTGPYPADTLFYRAVRGDFDIVVACYHDQGHAPIKVLGLEAGVNITVGLKGGIIRTSVDH
CCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEECCCEEEEEECCCEEEEECCC
GTAFDIAGKNLADERSMLEAIRVAVELAPKR
CCEEEECCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKPTIGITMGDAAGVGPEIIVKALQNSSIYEQCHPLVIGDAKILERAVRITNAGLTVRPI
CCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHCCCEEECCHHHHHHHHHHHCCCEEEEEH
SDIAEADYRYGMIDCLHLDLLPVDLPFGQVSAAAGDAAFQFLKRAIELAQNGEIDAICTA
HHHHHHHCCCCCEEEEEEEEEEECCCCCCHHHHCHHHHHHHHHHHHHHHCCCCEEEEEEC
PLNKEAMHKGGHLYPGHTEILADLTGTEDYAMMLSSPQLKVIHLTTHVGLIQAIEMINPE
CCCHHHHHCCCCCCCCHHHHEEECCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCC
RTYKVIKLAHDTLTRAGKEHPSIAVCGINPHAGENGLFGNGEEEEKLIPAIHKAQAEGIN
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
VTGPYPADTLFYRAVRGDFDIVVACYHDQGHAPIKVLGLEAGVNITVGLKGGIIRTSVDH
CCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEECCCEEEEEECCCEEEEECCC
GTAFDIAGKNLADERSMLEAIRVAVELAPKR
CCEEEECCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]