Click here to switch to the map view.

The map label for this gene is yugH [H]

Identifier: 138896518

GI number: 138896518

Start: 2990874

End: 2992046

Strand: Reverse

Name: yugH [H]

Synonym: GTNG_2881

Alternate gene names: 138896518

Gene position: 2992046-2990874 (Counterclockwise)

Preceding gene: 138896519

Following gene: 138896517

Centisome position: 84.28

GC content: 55.33

Gene sequence:

>1173_bases
ATGAATCCGCAAACGAAAAAAATGTATGTGTCAGAAACGGTTGCCAGCTTAAAGCCATCCGGCATCCGCCGGTTTTTCGA
TCTCGCTTCGAGCCTTGACGGTGTTATTTCCCTCGGTGTCGGCGAACCGGACTTTGTCACATCGTGGAGCATCCGCGAGG
CAAGCATTTTGTCGCTCGAGCAAGGCTATACGTCCTATACAGCCAACGCCGGTTTGCTCGAGCTGCGCCAAGAAATCGCC
GCCTATTTGCGCCGCAAGTTTCATGTGGAATACCGTCCGGAGACAGAAATTTTAGTGACGGTTGGGGCGAGCCAAGCGAT
TGATTTGGCGCTAAGGGCGATTGTCAATCCAGGTGATGAAGTGATCGTGGTGGAACCGAGTTTTGTCGCTTATGAACCGC
TTGTTGTGCTCGCCGGCGGGACGCCAGTGATCGTCCATGCGTCTGGCGCCGACGGGTTTCAGCTCATGCCGGCGCACATC
GAACGAGCGATCACTGAGCGGACGAAGGCCGTGATCATTTGTTCGCCGAACAATCCGACCGGAACGGTGCTTAGCCCAGC
GGAACTCAAAGCGCTCGCCCGCTTGGCGGAGAAGCATGATTTGCTGGTCATTGCCGACGAAATTTACGCCGAGCTCACGT
ATGAAGGTGAGCATACAAGCATGGCTGCTGTTCCCGGCATGCGCGAACGGACGATTTTGATTTCGGGCTTCTCCAAAGGA
TTTGCGATGACCGGTTGGCGGCTCGGTTTTGCGGCAGCGCCGGAAGAGCTTTTGCAGGCGATGTTGAAAATCCACCAATA
TGCGATGATGTGTGCGCCGACGATGGCGCAATACGGCGCCCTTGAAGCGCTCCGCAACGGGGAGCACGAGGTCGAACAAA
TGCGCAACAGCTACCGGCGGCGACGCAATTATTTCGTCGCCTCGCTCAATGAAATCGGGTTGCCGTGCCACTTGCCGGGA
GGCGCGTTTTACGCGTTTCCATCCATTCGCCATACCGGCTTGACGTCCGAACAGTTTGCCGAGCGGTTGCTTTTGGAAGA
AAAAGTGGCCGTTGTCCCTGGCAATGTCTTTGGTACAAGCGGAGAAGGCTATATTCGCTGTTCGTACGCTTCGTCGCTTG
AGCAGCTGCAGGAAGCGATTAAGCGGATGAAACGGTTTTTGGAACGCTTGTAA

Upstream 100 bases:

>100_bases
CCGTCATTTCGACGACCACCCATTTCATTTTGAAAAAATATAAACATGACGGCACGATATTCGACAAAGGAGATCAAGAT
CGTCGCATCGTGGTGGCACC

Downstream 100 bases:

>100_bases
TCGACGATGTTCTGCCATGGGCAGGACATCTTTTTTTGGGTTTTCCCTTTCGGTTATGTTATAATACAGAAACGTAGATG
AAACTAACCAATAGGAGTGT

Product: hypothetical protein

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNPQTKKMYVSETVASLKPSGIRRFFDLASSLDGVISLGVGEPDFVTSWSIREASILSLEQGYTSYTANAGLLELRQEIA
AYLRRKFHVEYRPETEILVTVGASQAIDLALRAIVNPGDEVIVVEPSFVAYEPLVVLAGGTPVIVHASGADGFQLMPAHI
ERAITERTKAVIICSPNNPTGTVLSPAELKALARLAEKHDLLVIADEIYAELTYEGEHTSMAAVPGMRERTILISGFSKG
FAMTGWRLGFAAAPEELLQAMLKIHQYAMMCAPTMAQYGALEALRNGEHEVEQMRNSYRRRRNYFVASLNEIGLPCHLPG
GAFYAFPSIRHTGLTSEQFAERLLLEEKVAVVPGNVFGTSGEGYIRCSYASSLEQLQEAIKRMKRFLERL

Sequences:

>Translated_390_residues
MNPQTKKMYVSETVASLKPSGIRRFFDLASSLDGVISLGVGEPDFVTSWSIREASILSLEQGYTSYTANAGLLELRQEIA
AYLRRKFHVEYRPETEILVTVGASQAIDLALRAIVNPGDEVIVVEPSFVAYEPLVVLAGGTPVIVHASGADGFQLMPAHI
ERAITERTKAVIICSPNNPTGTVLSPAELKALARLAEKHDLLVIADEIYAELTYEGEHTSMAAVPGMRERTILISGFSKG
FAMTGWRLGFAAAPEELLQAMLKIHQYAMMCAPTMAQYGALEALRNGEHEVEQMRNSYRRRRNYFVASLNEIGLPCHLPG
GAFYAFPSIRHTGLTSEQFAERLLLEEKVAVVPGNVFGTSGEGYIRCSYASSLEQLQEAIKRMKRFLERL
>Mature_390_residues
MNPQTKKMYVSETVASLKPSGIRRFFDLASSLDGVISLGVGEPDFVTSWSIREASILSLEQGYTSYTANAGLLELRQEIA
AYLRRKFHVEYRPETEILVTVGASQAIDLALRAIVNPGDEVIVVEPSFVAYEPLVVLAGGTPVIVHASGADGFQLMPAHI
ERAITERTKAVIICSPNNPTGTVLSPAELKALARLAEKHDLLVIADEIYAELTYEGEHTSMAAVPGMRERTILISGFSKG
FAMTGWRLGFAAAPEELLQAMLKIHQYAMMCAPTMAQYGALEALRNGEHEVEQMRNSYRRRRNYFVASLNEIGLPCHLPG
GAFYAFPSIRHTGLTSEQFAERLLLEEKVAVVPGNVFGTSGEGYIRCSYASSLEQLQEAIKRMKRFLERL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=399, Percent_Identity=29.5739348370927, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI169881279, Length=399, Percent_Identity=29.5739348370927, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI56713254, Length=389, Percent_Identity=28.7917737789203, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI56713256, Length=389, Percent_Identity=28.7917737789203, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI169881281, Length=301, Percent_Identity=28.2392026578073, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=25.531914893617, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI187936925, Length=391, Percent_Identity=25.3196930946292, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI14211921, Length=391, Percent_Identity=25.3196930946292, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI149944424, Length=386, Percent_Identity=24.0932642487047, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI7705897, Length=435, Percent_Identity=24.5977011494253, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI33469970, Length=435, Percent_Identity=24.5977011494253, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI215599424, Length=398, Percent_Identity=25.1256281407035, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI19263340, Length=398, Percent_Identity=25.1256281407035, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4885351, Length=363, Percent_Identity=23.9669421487603, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786816, Length=357, Percent_Identity=31.3725490196078, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1788722, Length=387, Percent_Identity=29.9741602067183, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1788627, Length=365, Percent_Identity=28.7671232876712, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1790797, Length=342, Percent_Identity=26.9005847953216, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788332, Length=233, Percent_Identity=29.1845493562232, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787909, Length=357, Percent_Identity=22.96918767507, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787710, Length=193, Percent_Identity=33.160621761658, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=391, Percent_Identity=31.2020460358056, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI71994476, Length=391, Percent_Identity=31.2020460358056, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17567369, Length=399, Percent_Identity=31.328320802005, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=25.8064516129032, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71981209, Length=372, Percent_Identity=22.8494623655914, Blast_Score=82, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=337, Percent_Identity=27.299703264095, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=371, Percent_Identity=26.1455525606469, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320317, Length=350, Percent_Identity=23.1428571428571, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=28.1653746770026, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=28.1653746770026, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=28.1653746770026, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=28.1653746770026, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI18859735, Length=390, Percent_Identity=24.8717948717949, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24641770, Length=393, Percent_Identity=25.6997455470738, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24641760, Length=393, Percent_Identity=25.6997455470738, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24641768, Length=393, Percent_Identity=25.6997455470738, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24641766, Length=393, Percent_Identity=25.6997455470738, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24641764, Length=393, Percent_Identity=25.6997455470738, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI45551451, Length=393, Percent_Identity=25.6997455470738, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42962; Mature: 42962

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPQTKKMYVSETVASLKPSGIRRFFDLASSLDGVISLGVGEPDFVTSWSIREASILSLE
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEECCCCHHHHEEHH
QGYTSYTANAGLLELRQEIAAYLRRKFHVEYRPETEILVTVGASQAIDLALRAIVNPGDE
CCCCEECCCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCHHHHHHHHHHCCCCCC
VIVVEPSFVAYEPLVVLAGGTPVIVHASGADGFQLMPAHIERAITERTKAVIICSPNNPT
EEEECCCCEEECCEEEEECCCEEEEEECCCCCCEECHHHHHHHHHHCCCEEEEECCCCCC
GTVLSPAELKALARLAEKHDLLVIADEIYAELTYEGEHTSMAAVPGMRERTILISGFSKG
CCEECHHHHHHHHHHHHHCCEEEEEEHHEEEEEECCCCCCEEECCCCCCCEEEEEECCCC
FAMTGWRLGFAAAPEELLQAMLKIHQYAMMCAPTMAQYGALEALRNGEHEVEQMRNSYRR
CEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RRNYFVASLNEIGLPCHLPGGAFYAFPSIRHTGLTSEQFAERLLLEEKVAVVPGNVFGTS
HHHHEEEEHHHCCCCEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHEEECCCEECCC
GEGYIRCSYASSLEQLQEAIKRMKRFLERL
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNPQTKKMYVSETVASLKPSGIRRFFDLASSLDGVISLGVGEPDFVTSWSIREASILSLE
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEECCCCHHHHEEHH
QGYTSYTANAGLLELRQEIAAYLRRKFHVEYRPETEILVTVGASQAIDLALRAIVNPGDE
CCCCEECCCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCHHHHHHHHHHCCCCCC
VIVVEPSFVAYEPLVVLAGGTPVIVHASGADGFQLMPAHIERAITERTKAVIICSPNNPT
EEEECCCCEEECCEEEEECCCEEEEEECCCCCCEECHHHHHHHHHHCCCEEEEECCCCCC
GTVLSPAELKALARLAEKHDLLVIADEIYAELTYEGEHTSMAAVPGMRERTILISGFSKG
CCEECHHHHHHHHHHHHHCCEEEEEEHHEEEEEECCCCCCEEECCCCCCCEEEEEECCCC
FAMTGWRLGFAAAPEELLQAMLKIHQYAMMCAPTMAQYGALEALRNGEHEVEQMRNSYRR
CEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RRNYFVASLNEIGLPCHLPGGAFYAFPSIRHTGLTSEQFAERLLLEEKVAVVPGNVFGTS
HHHHEEEEHHHCCCCEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHEEECCCEECCC
GEGYIRCSYASSLEQLQEAIKRMKRFLERL
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]