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The map label for this gene is yrhP [H]

Identifier: 138896423

GI number: 138896423

Start: 2904373

End: 2904999

Strand: Direct

Name: yrhP [H]

Synonym: GTNG_2786

Alternate gene names: 138896423

Gene position: 2904373-2904999 (Clockwise)

Preceding gene: 138896420

Following gene: 138896426

Centisome position: 81.81

GC content: 53.11

Gene sequence:

>627_bases
ATGGAAATGGATACAGCTTTATCGTTTTTAAGTGTCGCTGTTGTGCTGACGCTCGCCCCAGGCCCAGATATTTTATTCGT
CATCGCCCAAAGCCTATCTCAAGGCAAAAACGCGGGTATCGCCACCGCGCTCGGGCTTTGTACAGGGCTTGTCGTCCATA
TTAGTGCGGCGGTGCTCGGCGTCTCGGCCGTCATTTACCAATCGGCCTTAGCGTTTGCCATCGTCAAATACGCAGGCGCC
GCTTATTTGCTTTACTTGGCATGGCAAGCGTTCAACGAAAAAGACGCCGGCTTGGCGCTCGAGCGTCAAGAGCGGCTAAC
CTTGATGTCACTGTACAAAAAAGGCATTTTTATGAACGTGCTCAATCCGAAAGTGTCCCTCTTCTTTTTGGCGCTATTGC
CGCAATTCGTCCATCCGTCAGCGGGCCAAATCCCGCGGCAAATGCTGGTGTTAGGCGTCATCTTTCTCGTTCAAGCGCTC
GTTGTCTTCACCTTAGTGAGCATCGGTGCGGAAAAACTGCGCCATTGGCTGTTGTCGAACGAACGAATCGCTCGGCGGAT
CCATTGGCTAAAAGGCGTCCTCTTTGCCGTCATCGGCATCCAAATCGCCTTCAGCGAGCGGTCGTAG

Upstream 100 bases:

>100_bases
GGGAAATGAATCCATTTTTAGCGAGAAAAAAGGAATTCAACGGGAGCATGGCGAACCTTAGGAATCATCGTCATGATCAA
CAACCAAAGAGGTGTGTTCG

Downstream 100 bases:

>100_bases
GGGGCAAACAAAGCGAGCGGGCTGTTTTGGCAAGCCCGCTCATCATGCTTTCGTCTGCAACAGCTTCACACCAAGCCCAA
CAAACACAATCCCCGTCAAT

Product: hypothetical protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MEMDTALSFLSVAVVLTLAPGPDILFVIAQSLSQGKNAGIATALGLCTGLVVHISAAVLGVSAVIYQSALAFAIVKYAGA
AYLLYLAWQAFNEKDAGLALERQERLTLMSLYKKGIFMNVLNPKVSLFFLALLPQFVHPSAGQIPRQMLVLGVIFLVQAL
VVFTLVSIGAEKLRHWLLSNERIARRIHWLKGVLFAVIGIQIAFSERS

Sequences:

>Translated_208_residues
MEMDTALSFLSVAVVLTLAPGPDILFVIAQSLSQGKNAGIATALGLCTGLVVHISAAVLGVSAVIYQSALAFAIVKYAGA
AYLLYLAWQAFNEKDAGLALERQERLTLMSLYKKGIFMNVLNPKVSLFFLALLPQFVHPSAGQIPRQMLVLGVIFLVQAL
VVFTLVSIGAEKLRHWLLSNERIARRIHWLKGVLFAVIGIQIAFSERS
>Mature_208_residues
MEMDTALSFLSVAVVLTLAPGPDILFVIAQSLSQGKNAGIATALGLCTGLVVHISAAVLGVSAVIYQSALAFAIVKYAGA
AYLLYLAWQAFNEKDAGLALERQERLTLMSLYKKGIFMNVLNPKVSLFFLALLPQFVHPSAGQIPRQMLVLGVIFLVQAL
VVFTLVSIGAEKLRHWLLSNERIARRIHWLKGVLFAVIGIQIAFSERS

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=202, Percent_Identity=30.1980198019802, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788099, Length=189, Percent_Identity=25.9259259259259, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48994978, Length=207, Percent_Identity=27.536231884058, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786522, Length=176, Percent_Identity=22.7272727272727, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22595; Mature: 22595

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMDTALSFLSVAVVLTLAPGPDILFVIAQSLSQGKNAGIATALGLCTGLVVHISAAVLG
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
VSAVIYQSALAFAIVKYAGAAYLLYLAWQAFNEKDAGLALERQERLTLMSLYKKGIFMNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHH
LNPKVSLFFLALLPQFVHPSAGQIPRQMLVLGVIFLVQALVVFTLVSIGAEKLRHWLLSN
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ERIARRIHWLKGVLFAVIGIQIAFSERS
HHHHHHHHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure
MEMDTALSFLSVAVVLTLAPGPDILFVIAQSLSQGKNAGIATALGLCTGLVVHISAAVLG
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
VSAVIYQSALAFAIVKYAGAAYLLYLAWQAFNEKDAGLALERQERLTLMSLYKKGIFMNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHH
LNPKVSLFFLALLPQFVHPSAGQIPRQMLVLGVIFLVQALVVFTLVSIGAEKLRHWLLSN
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ERIARRIHWLKGVLFAVIGIQIAFSERS
HHHHHHHHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]