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The map label for this gene is etfA [H]

Identifier: 138896250

GI number: 138896250

Start: 2720479

End: 2721456

Strand: Reverse

Name: etfA [H]

Synonym: GTNG_2613

Alternate gene names: 138896250

Gene position: 2721456-2720479 (Counterclockwise)

Preceding gene: 138896251

Following gene: 138896249

Centisome position: 76.65

GC content: 52.97

Gene sequence:

>978_bases
ATGGCACGCAAAGTATTAACATTAGCAGAAGTTCGCGACGGATCGCTGCGGAACGTTTCGTTTGAAGCGATCGCAGCAGC
CAAAACGATCGCTGAAGGCGGGGAAGTCGTAGCGGCACTTGTCGGCGATCAAGTGCAAGCGCATGCAAATGAGCTGATTT
TCCGCGGGGCGGATCGCGTCGTTGTCGTTGAGCATCCGAACTTGAAATTTTATACGTCCGACGGCTATTCGCAAGCGTTA
AAAGCGGTGATCGATAAAGAACAGCCAGAAGCCATTGTCTTTGGTCATACAGCGCTTGGCAAAGACCTGTCGCCGAAGCT
GGCCGTTAAACTTGACGCCGGTCTTGTTTCCGACGTGGTGGCAGTCGAAGAAGTAGGCGGCAACATTGTGTTCACGCGCC
CGATCTACTCCGGTAAAGCGTTTGAAAAGAAAATCGTCACCGACGGCATCATGTTTGTGACGGTGCGTCCGAACAACATC
GCATCGCTTGAGCGTGACGAATCGCGCTCCGGCAGCGTTGAATCATTGGCGGTCGAAATTAAAGATTTGCGCGCGATCGT
CAAAGAAGTCGTCCGCAAAACCGCTGAAGGGGTCGACCTGACGGAAGCGAAAGTGATTGTCGCTGGCGGCCGCGGTGTGA
AAAGCGCGGAAGGCTTCAAGCCGCTCCAAGAGCTGGCGGAAGTGTTGGGCGGCGCAGTCGGTGCGTCACGTGGAGCGTGC
GATGCCGGCTATTGTGACTACTCGCTGCAAATCGGGCAAACCGGGAAAGTCGTAACACCAGATCTTTACATCGCCTGCGG
TATCTCAGGTGCTATTCAGCATTTGGCAGGCATGTCGAACTCAAAAGTGATCGTCGCCATTAACAAAGACCCGGAAGCCA
ATATCTTTAAAGTCGCTGATTACGGCATTGTCGGCGATTTGTTTGAAGTCGTTCCTCTCCTCACGGAAGAGTTTAAAAAG
CTGAAAGTGCATTCGTAA

Upstream 100 bases:

>100_bases
TCCGTTCCGAAGCGAAAGTCGTTTAAAGCGGCAGACGGTATGGTTGTTAGCGCTCTCTAACGGACGGAAAACATGAACAA
AAGGGTAGGGGGACTGAAAC

Downstream 100 bases:

>100_bases
TCGATTCAAACGGGTAGCGTGGTATGCGCTGCCCGTTTTTTTTTGGATAAATTGAACCGCGAAGCGAATATTAGAAACGA
GGCAAAATATTCGCGTCGTT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MARKVLTLAEVRDGSLRNVSFEAIAAAKTIAEGGEVVAALVGDQVQAHANELIFRGADRVVVVEHPNLKFYTSDGYSQAL
KAVIDKEQPEAIVFGHTALGKDLSPKLAVKLDAGLVSDVVAVEEVGGNIVFTRPIYSGKAFEKKIVTDGIMFVTVRPNNI
ASLERDESRSGSVESLAVEIKDLRAIVKEVVRKTAEGVDLTEAKVIVAGGRGVKSAEGFKPLQELAEVLGGAVGASRGAC
DAGYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEANIFKVADYGIVGDLFEVVPLLTEEFKK
LKVHS

Sequences:

>Translated_325_residues
MARKVLTLAEVRDGSLRNVSFEAIAAAKTIAEGGEVVAALVGDQVQAHANELIFRGADRVVVVEHPNLKFYTSDGYSQAL
KAVIDKEQPEAIVFGHTALGKDLSPKLAVKLDAGLVSDVVAVEEVGGNIVFTRPIYSGKAFEKKIVTDGIMFVTVRPNNI
ASLERDESRSGSVESLAVEIKDLRAIVKEVVRKTAEGVDLTEAKVIVAGGRGVKSAEGFKPLQELAEVLGGAVGASRGAC
DAGYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEANIFKVADYGIVGDLFEVVPLLTEEFKK
LKVHS
>Mature_324_residues
ARKVLTLAEVRDGSLRNVSFEAIAAAKTIAEGGEVVAALVGDQVQAHANELIFRGADRVVVVEHPNLKFYTSDGYSQALK
AVIDKEQPEAIVFGHTALGKDLSPKLAVKLDAGLVSDVVAVEEVGGNIVFTRPIYSGKAFEKKIVTDGIMFVTVRPNNIA
SLERDESRSGSVESLAVEIKDLRAIVKEVVRKTAEGVDLTEAKVIVAGGRGVKSAEGFKPLQELAEVLGGAVGASRGACD
AGYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEANIFKVADYGIVGDLFEVVPLLTEEFKKL
KVHS

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=319, Percent_Identity=40.1253918495298, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI189181759, Length=284, Percent_Identity=41.9014084507042, Blast_Score=194, Evalue=1e-49,
Organism=Escherichia coli, GI1787990, Length=290, Percent_Identity=33.1034482758621, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786226, Length=230, Percent_Identity=29.5652173913043, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082157, Length=242, Percent_Identity=26.8595041322314, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=314, Percent_Identity=42.3566878980892, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6325261, Length=238, Percent_Identity=42.0168067226891, Blast_Score=175, Evalue=9e-45,
Organism=Drosophila melanogaster, GI17136898, Length=318, Percent_Identity=41.8238993710692, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24652801, Length=318, Percent_Identity=41.8238993710692, Blast_Score=206, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 34419; Mature: 34288

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKVLTLAEVRDGSLRNVSFEAIAAAKTIAEGGEVVAALVGDQVQAHANELIFRGADRV
CCCCEEEHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHCCHHHHHHHHHEEECCCEE
VVVEHPNLKFYTSDGYSQALKAVIDKEQPEAIVFGHTALGKDLSPKLAVKLDAGLVSDVV
EEEECCCEEEEECCCHHHHHHHHHCCCCCCEEEEECHHCCCCCCCCEEEEECCCHHHHHH
AVEEVGGNIVFTRPIYSGKAFEKKIVTDGIMFVTVRPNNIASLERDESRSGSVESLAVEI
HHHHCCCCEEEECCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
KDLRAIVKEVVRKTAEGVDLTEAKVIVAGGRGVKSAEGFKPLQELAEVLGGAVGASRGAC
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
DAGYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEANIFKVAD
CCCCCCEEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEC
YGIVGDLFEVVPLLTEEFKKLKVHS
CCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARKVLTLAEVRDGSLRNVSFEAIAAAKTIAEGGEVVAALVGDQVQAHANELIFRGADRV
CCCEEEHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHCCHHHHHHHHHEEECCCEE
VVVEHPNLKFYTSDGYSQALKAVIDKEQPEAIVFGHTALGKDLSPKLAVKLDAGLVSDVV
EEEECCCEEEEECCCHHHHHHHHHCCCCCCEEEEECHHCCCCCCCCEEEEECCCHHHHHH
AVEEVGGNIVFTRPIYSGKAFEKKIVTDGIMFVTVRPNNIASLERDESRSGSVESLAVEI
HHHHCCCCEEEECCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
KDLRAIVKEVVRKTAEGVDLTEAKVIVAGGRGVKSAEGFKPLQELAEVLGGAVGASRGAC
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
DAGYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEANIFKVAD
CCCCCCEEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEC
YGIVGDLFEVVPLLTEEFKKLKVHS
CCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]