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The map label for this gene is gluP [H]

Identifier: 138896022

GI number: 138896022

Start: 2498869

End: 2500029

Strand: Reverse

Name: gluP [H]

Synonym: GTNG_2385

Alternate gene names: 138896022

Gene position: 2500029-2498869 (Counterclockwise)

Preceding gene: 138896023

Following gene: 138896020

Centisome position: 70.42

GC content: 51.77

Gene sequence:

>1161_bases
ATGGATGTATTGTTTTGGCAGCTTGTTCGTCTTTTAATCCATAGCGGCTACCGCATCGCACAGATGTCTGAGCGCGGCGA
TGAAATATGGCTTGAATCGGGCCACTGGCGGCGTCCGACGATTGTCCGTCTTGTGCGCGCCGATTTTGATTGGAGCCGGT
CGCTGCGCCTCGATATCGAGTATACATGGCAATTTGTCCGGCAAATGAATGGACGAAAAATCGGCAAAGGAGGCCATGTC
GTCAATGTATATGTGATGGCGTATCCGCCGGTCGACGATTGGGAATTTCTTGTAGATGAACCGCTTCCACTTTCCGAGCC
AGCGGATGGCGCGTTTCATACGCTTCTCATTCATAGCAGCAACACAGCTGAGATGTTGCCGCGCCTTGCGGACATGACCG
GCGCCACGATCCGACCGGAGCCGCTCACGGAGGGAGCCGACCCGTTTGCCACCGCCGAGCGTTTGAAATATGAAGTGCTA
ACGGAATGGCGCCGTGAGCAGGAAGAAGAACGCCGCATTTTTGAATACGGCAAGCCCTTGTTCACAAGGCTGTTGATCGT
CGTGCAAGTGGTGATGTTTCTCATTCTCGAATGGAGCGGCGGCAGCACGGACCCGAGCGTCTTAATCCGTTATGGCGCTA
AGTTTAACCCGCTCATTGAAATGGGGGAATGGTGGCGCTTTTTAACGCCGATGTTTTTACATATCGGGTTTTTGCATTTG
CTGACCAACACGTTCGCTTTATATTATTTAGGAATAACGGTTGAACGGCTGTATGGTTCGCTTCGATTTTTGCTCATTTA
TACAACAGCCGGCTTTTTTGGGACGTTAGCGAGTTTTTTGTTTACCCCTTCTATCTCTGCCGGGGCGTCTGGCGCCATTT
TTGGATTGTTTGGGGCGCTTCTTTATTTCGGTACGGTATATCGGCACTTGTTTTTTCGCACAATGGGGATGAACGTAGTC
AGCTTAATTGTTGTGAACTTACTGTTTGGTCTGCTTGTCCCTGGCATTGATAACGCCGGCCATATCGGTGGACTAGTCGG
TGGCTTTTTGGCCGCGGGCGCTGTCCATTTACCGAAGCGTGCCGCTTGGGGAAGACAGATGAAGGCGTTGGTTGTTGCCG
CGTTGTTGGCCGCCGCCGGTTTATGGCTTGGTTTTCGCTAA

Upstream 100 bases:

>100_bases
CGTCCGTCCCAGTGTGCCGGACGGTCGGCGAATTGACCGCCTTGCTGCTCAATGGGCTTGGCCTCGTCGGAGAAAGGGAG
AGGAGAACGTGATCGGAACG

Downstream 100 bases:

>100_bases
GGGACTTGGATAAGCATCACTTTTTCGTCGTTTTTCGCCTCTAGCAAGATGAGGATTCTACGATAATCTTTTTGAATCAA
AATGAGTGGCATCGTGCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MDVLFWQLVRLLIHSGYRIAQMSERGDEIWLESGHWRRPTIVRLVRADFDWSRSLRLDIEYTWQFVRQMNGRKIGKGGHV
VNVYVMAYPPVDDWEFLVDEPLPLSEPADGAFHTLLIHSSNTAEMLPRLADMTGATIRPEPLTEGADPFATAERLKYEVL
TEWRREQEEERRIFEYGKPLFTRLLIVVQVVMFLILEWSGGSTDPSVLIRYGAKFNPLIEMGEWWRFLTPMFLHIGFLHL
LTNTFALYYLGITVERLYGSLRFLLIYTTAGFFGTLASFLFTPSISAGASGAIFGLFGALLYFGTVYRHLFFRTMGMNVV
SLIVVNLLFGLLVPGIDNAGHIGGLVGGFLAAGAVHLPKRAAWGRQMKALVVAALLAAAGLWLGFR

Sequences:

>Translated_386_residues
MDVLFWQLVRLLIHSGYRIAQMSERGDEIWLESGHWRRPTIVRLVRADFDWSRSLRLDIEYTWQFVRQMNGRKIGKGGHV
VNVYVMAYPPVDDWEFLVDEPLPLSEPADGAFHTLLIHSSNTAEMLPRLADMTGATIRPEPLTEGADPFATAERLKYEVL
TEWRREQEEERRIFEYGKPLFTRLLIVVQVVMFLILEWSGGSTDPSVLIRYGAKFNPLIEMGEWWRFLTPMFLHIGFLHL
LTNTFALYYLGITVERLYGSLRFLLIYTTAGFFGTLASFLFTPSISAGASGAIFGLFGALLYFGTVYRHLFFRTMGMNVV
SLIVVNLLFGLLVPGIDNAGHIGGLVGGFLAAGAVHLPKRAAWGRQMKALVVAALLAAAGLWLGFR
>Mature_386_residues
MDVLFWQLVRLLIHSGYRIAQMSERGDEIWLESGHWRRPTIVRLVRADFDWSRSLRLDIEYTWQFVRQMNGRKIGKGGHV
VNVYVMAYPPVDDWEFLVDEPLPLSEPADGAFHTLLIHSSNTAEMLPRLADMTGATIRPEPLTEGADPFATAERLKYEVL
TEWRREQEEERRIFEYGKPLFTRLLIVVQVVMFLILEWSGGSTDPSVLIRYGAKFNPLIEMGEWWRFLTPMFLHIGFLHL
LTNTFALYYLGITVERLYGSLRFLLIYTTAGFFGTLASFLFTPSISAGASGAIFGLFGALLYFGTVYRHLFFRTMGMNVV
SLIVVNLLFGLLVPGIDNAGHIGGLVGGFLAAGAVHLPKRAAWGRQMKALVVAALLAAAGLWLGFR

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Caenorhabditis elegans, GI115534507, Length=140, Percent_Identity=32.1428571428571, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 43656; Mature: 43656

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLFWQLVRLLIHSGYRIAQMSERGDEIWLESGHWRRPTIVRLVRADFDWSRSLRLDIE
CCCHHHHHHHHHHHCCCCEEHHHCCCCEEEECCCCCCCCHHHHHHHCCCCCCCCEEEEHH
YTWQFVRQMNGRKIGKGGHVVNVYVMAYPPVDDWEFLVDEPLPLSEPADGAFHTLLIHSS
HHHHHHHHHCCCEECCCCCEEEEEEEEECCCCCCHHHCCCCCCCCCCCCCCEEEEEEECC
NTAEMLPRLADMTGATIRPEPLTEGADPFATAERLKYEVLTEWRREQEEERRIFEYGKPL
CHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FTRLLIVVQVVMFLILEWSGGSTDPSVLIRYGAKFNPLIEMGEWWRFLTPMFLHIGFLHL
HHHHHHHHHHHHHHHEECCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LTNTFALYYLGITVERLYGSLRFLLIYTTAGFFGTLASFLFTPSISAGASGAIFGLFGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LYFGTVYRHLFFRTMGMNVVSLIVVNLLFGLLVPGIDNAGHIGGLVGGFLAAGAVHLPKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHCCHH
AAWGRQMKALVVAALLAAAGLWLGFR
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDVLFWQLVRLLIHSGYRIAQMSERGDEIWLESGHWRRPTIVRLVRADFDWSRSLRLDIE
CCCHHHHHHHHHHHCCCCEEHHHCCCCEEEECCCCCCCCHHHHHHHCCCCCCCCEEEEHH
YTWQFVRQMNGRKIGKGGHVVNVYVMAYPPVDDWEFLVDEPLPLSEPADGAFHTLLIHSS
HHHHHHHHHCCCEECCCCCEEEEEEEEECCCCCCHHHCCCCCCCCCCCCCCEEEEEEECC
NTAEMLPRLADMTGATIRPEPLTEGADPFATAERLKYEVLTEWRREQEEERRIFEYGKPL
CHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FTRLLIVVQVVMFLILEWSGGSTDPSVLIRYGAKFNPLIEMGEWWRFLTPMFLHIGFLHL
HHHHHHHHHHHHHHHEECCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LTNTFALYYLGITVERLYGSLRFLLIYTTAGFFGTLASFLFTPSISAGASGAIFGLFGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LYFGTVYRHLFFRTMGMNVVSLIVVNLLFGLLVPGIDNAGHIGGLVGGFLAAGAVHLPKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHCCHH
AAWGRQMKALVVAALLAAAGLWLGFR
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]