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The map label for this gene is argK [C]

Identifier: 138895939

GI number: 138895939

Start: 2417155

End: 2418300

Strand: Reverse

Name: argK [C]

Synonym: GTNG_2298

Alternate gene names: 138895939

Gene position: 2418300-2417155 (Counterclockwise)

Preceding gene: 138895940

Following gene: 138895938

Centisome position: 68.12

GC content: 56.72

Gene sequence:

>1146_bases
ATGAACGGTGAAGAGAAACAACAAGAACGAGCAGGCGGCGAAGGTGCGGTAGACGGTCAAGGGAAGCGTCCCGAATGGGC
GGACGGCGAGAGCGCGTCATCGTACGTGCAAGCTAAGCGCCCGTCGGCGCCCAAGCGGCTTGTGAAACGAAAAGAACGGT
CGGTCGCTGATTACGTCCAAGGAGTGCTGGCCGGCGACCGCACCCTTTTAGCCCAGGCGATTACGCTTGTTGAAAGCAAT
GCGGCGAGGCATTTAGAGCTTGCCCAACAAGTGTTGAATGAATTGTTGCCGCATGTCGGCCGTTCGATTCGCATCGGCGT
TACTGGCGTGCCGGGAGCGGGGAAAAGCACGTTCATTGAAGCGTTCGGTACGTTTTTATGCGAACAGGGGCATCGCGTCG
CCGTCCTAGCCGTCGATCCGACGAGCTCGTTGACCGGCGGCAGCATCCTCGGCGATAAAACACGGATGGAGACGCTCGCC
CGGAATCCGCGCGCTTTCATCCGTCCGTCTCCATCAGGCGGGGCGCTTGGTGGCGTGCACCGGAAAACGCGGGAGACGAT
GATGCTTTGCGAGGCGGCCGGTTATGACATTATCCTCGTTGAGACGGTCGGCGTCGGGCAAAGCGAGTTTGTCGTCCGTG
GGATGGTTGATTTTTTCCTTCTTTTGGCGTTAACTGGCGCCGGCGACGAACTGCAAGGGATGAAGCGCGGCATTATGGAG
CTGGTCGATGCCATCGTCATCAATAAGGCGGACGGTGACAATAAAGAAAAAGCGCGGGCCGCGCAAAAAGAGTACAATCA
GTTTCTTCACTACTTGCGCCCGGCCACGCCCGGCTGGCAGACAAAAGCGTACACATGCTCCGCCTTGTGGGGAGAAGGAA
TCGCCGACATTTGGCAAGTCATTGAAACGTTTGTCAAAACGACAAAGCAATCCGGCGTGTTTGATGACCGCCGCCGCCAG
CAACAAAAAGACTGGATGCATGCGATGATCAAAGAATATGTAGAAACGCGCTTTTTCGCCGATCCGATCGTGAAAGAAAA
GCTCCCGGCGCTTGAGAACAGCGTTATTTCCGGCTCGAAACCGGTCACTGCCGCTGTCAGGGAGCTGATCGAAGCGTATG
AACGGGGGATTGGCGGTCAAATATGA

Upstream 100 bases:

>100_bases
GAGCCGCTGCCGTCTTCGGGCCGGGCACGGTGATTCCGGAAGCGGCAGAAACCGTATTAGACGAAATTTATGCTCGACTC
GGCTATGAGGAAGTGAGCGA

Downstream 100 bases:

>100_bases
TATGATAAAACGTAAGGAGGTGTCATGATGTTCCAATTTCAATTTCCGCTCTACAATGATTTTGTAGAACAATCCCGCCG
CGAAGCGGTCGAAGCCGGAT

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MNGEEKQQERAGGEGAVDGQGKRPEWADGESASSYVQAKRPSAPKRLVKRKERSVADYVQGVLAGDRTLLAQAITLVESN
AARHLELAQQVLNELLPHVGRSIRIGVTGVPGAGKSTFIEAFGTFLCEQGHRVAVLAVDPTSSLTGGSILGDKTRMETLA
RNPRAFIRPSPSGGALGGVHRKTRETMMLCEAAGYDIILVETVGVGQSEFVVRGMVDFFLLLALTGAGDELQGMKRGIME
LVDAIVINKADGDNKEKARAAQKEYNQFLHYLRPATPGWQTKAYTCSALWGEGIADIWQVIETFVKTTKQSGVFDDRRRQ
QQKDWMHAMIKEYVETRFFADPIVKEKLPALENSVISGSKPVTAAVRELIEAYERGIGGQI

Sequences:

>Translated_381_residues
MNGEEKQQERAGGEGAVDGQGKRPEWADGESASSYVQAKRPSAPKRLVKRKERSVADYVQGVLAGDRTLLAQAITLVESN
AARHLELAQQVLNELLPHVGRSIRIGVTGVPGAGKSTFIEAFGTFLCEQGHRVAVLAVDPTSSLTGGSILGDKTRMETLA
RNPRAFIRPSPSGGALGGVHRKTRETMMLCEAAGYDIILVETVGVGQSEFVVRGMVDFFLLLALTGAGDELQGMKRGIME
LVDAIVINKADGDNKEKARAAQKEYNQFLHYLRPATPGWQTKAYTCSALWGEGIADIWQVIETFVKTTKQSGVFDDRRRQ
QQKDWMHAMIKEYVETRFFADPIVKEKLPALENSVISGSKPVTAAVRELIEAYERGIGGQI
>Mature_381_residues
MNGEEKQQERAGGEGAVDGQGKRPEWADGESASSYVQAKRPSAPKRLVKRKERSVADYVQGVLAGDRTLLAQAITLVESN
AARHLELAQQVLNELLPHVGRSIRIGVTGVPGAGKSTFIEAFGTFLCEQGHRVAVLAVDPTSSLTGGSILGDKTRMETLA
RNPRAFIRPSPSGGALGGVHRKTRETMMLCEAAGYDIILVETVGVGQSEFVVRGMVDFFLLLALTGAGDELQGMKRGIME
LVDAIVINKADGDNKEKARAAQKEYNQFLHYLRPATPGWQTKAYTCSALWGEGIADIWQVIETFVKTTKQSGVFDDRRRQ
QQKDWMHAMIKEYVETRFFADPIVKEKLPALENSVISGSKPVTAAVRELIEAYERGIGGQI

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=358, Percent_Identity=45.8100558659218, Blast_Score=299, Evalue=4e-81,
Organism=Escherichia coli, GI1789285, Length=311, Percent_Identity=49.5176848874598, Blast_Score=303, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI71994271, Length=337, Percent_Identity=42.7299703264095, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71994275, Length=272, Percent_Identity=45.5882352941176, Blast_Score=246, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 41599; Mature: 41599

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGEEKQQERAGGEGAVDGQGKRPEWADGESASSYVQAKRPSAPKRLVKRKERSVADYVQ
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
GVLAGDRTLLAQAITLVESNAARHLELAQQVLNELLPHVGRSIRIGVTGVPGAGKSTFIE
HHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
AFGTFLCEQGHRVAVLAVDPTSSLTGGSILGDKTRMETLARNPRAFIRPSPSGGALGGVH
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCHHH
RKTRETMMLCEAAGYDIILVETVGVGQSEFVVRGMVDFFLLLALTGAGDELQGMKRGIME
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LVDAIVINKADGDNKEKARAAQKEYNQFLHYLRPATPGWQTKAYTCSALWGEGIADIWQV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCCHHHHHHH
IETFVKTTKQSGVFDDRRRQQQKDWMHAMIKEYVETRFFADPIVKEKLPALENSVISGSK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC
PVTAAVRELIEAYERGIGGQI
CHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNGEEKQQERAGGEGAVDGQGKRPEWADGESASSYVQAKRPSAPKRLVKRKERSVADYVQ
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
GVLAGDRTLLAQAITLVESNAARHLELAQQVLNELLPHVGRSIRIGVTGVPGAGKSTFIE
HHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
AFGTFLCEQGHRVAVLAVDPTSSLTGGSILGDKTRMETLARNPRAFIRPSPSGGALGGVH
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCHHH
RKTRETMMLCEAAGYDIILVETVGVGQSEFVVRGMVDFFLLLALTGAGDELQGMKRGIME
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LVDAIVINKADGDNKEKARAAQKEYNQFLHYLRPATPGWQTKAYTCSALWGEGIADIWQV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCCHHHHHHH
IETFVKTTKQSGVFDDRRRQQQKDWMHAMIKEYVETRFFADPIVKEKLPALENSVISGSK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC
PVTAAVRELIEAYERGIGGQI
CHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]