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The map label for this gene is tdcB [C]

Identifier: 138895917

GI number: 138895917

Start: 2393901

End: 2394929

Strand: Reverse

Name: tdcB [C]

Synonym: GTNG_2276

Alternate gene names: 138895917

Gene position: 2394929-2393901 (Counterclockwise)

Preceding gene: 138895918

Following gene: 138895916

Centisome position: 67.46

GC content: 41.21

Gene sequence:

>1029_bases
ATGAATAATCAAGGAGTGATGATCTTGGGAGATTTACAAACGATAAGAGAAGAACTATCGATCAGAGATATATGGGAAGC
GCGGAAAAGAATTGTTTCAATTGTAAATAAAACTCCGTTAATACAGTCGTTTGTTTTATCAGAAAAGGCCGGACGCCCCG
TCTATTTAAAACTTGAAAATGTACATGATATTGGGGCCTTCAAAGTTAGGGGGGCTGCCAACAAAATATTAAGTTTGAGT
GAGGATGAAAAGAAAAAAGGGGTTGCGACGTTTTCTACCGGGAATCATGGCATGGCGGTTGCCTATGTAGCGAAATCCCT
TGGCATTAACGCGGTTGTTTGTATTTCGAACCGCGTTCCGGAGGCGAAGTTGGAATCATTAAGAAGATTGAACGCCCAAA
TTGAAATATACGGCCATAGCCAAGATGATGCGGAAGAATATTGTTATCATTTGGCCGAAAAGAAAGGATTAACGATTATC
CCCCCATTTGACGATCCACATATTATTGCAGGTCAAGGAACTATTGGATTAGAAATCGTCGAGGACGTTCCACATGTAAC
AGACGTCATCGTTCCTCTTTCCGGGGGAGGGCTTTTGTCAGGAATCGGTTTAGCTTTAAAATCAATCGATCCTAATATTC
GGGTCATCGGTGTTTCTGCTGAACACGCACCAGTTATGTATGAGAGTTTGAAGGCACGAAAAGCTGTAAAAATAGAAGAA
AGAGATACGCTTGCTGATAGTTTGCTTGGTGGCATTGGCATGGATAATCAGTACACTCTTCAAATGGTCGGTCAATATAC
AGATGATATTTTACTGATATCGGAAGAGGAGATTGCCTATAGCATGGCTTTTATGATGGATAAACACCATATGATTATAG
AAGGAGCAGCGGCCACAGGTGTTGCGGCCGTTTTAGAAAATAAGCTTCCTCGTCATGATGGTGCGATTGTGATCGTGATC
AGTGGACATAATGTAGATCTTTCTGTGCTTTTCCAATTGATTCAGCGTTACAACGATTTGTCTCATTAA

Upstream 100 bases:

>100_bases
TTGTACAAGGTTATTAAAGTTGTATGAAAAAATATTTTTTTACTATTCAATTTTGATAATTGAGTACAGAAAATTCATAC
TATATAATCCTTGGTAAAGT

Downstream 100 bases:

>100_bases
ACCACTAACAATAAGAGGTGGGACTCGATGGCAACCGCTAATACCAATAGTAAGGTTCGGATTGAAAGGGATTTCCTAGG
GGATAAAGAAGTTCCGATAG

Product: threonine dehydratase-like protein

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNNQGVMILGDLQTIREELSIRDIWEARKRIVSIVNKTPLIQSFVLSEKAGRPVYLKLENVHDIGAFKVRGAANKILSLS
EDEKKKGVATFSTGNHGMAVAYVAKSLGINAVVCISNRVPEAKLESLRRLNAQIEIYGHSQDDAEEYCYHLAEKKGLTII
PPFDDPHIIAGQGTIGLEIVEDVPHVTDVIVPLSGGGLLSGIGLALKSIDPNIRVIGVSAEHAPVMYESLKARKAVKIEE
RDTLADSLLGGIGMDNQYTLQMVGQYTDDILLISEEEIAYSMAFMMDKHHMIIEGAAATGVAAVLENKLPRHDGAIVIVI
SGHNVDLSVLFQLIQRYNDLSH

Sequences:

>Translated_342_residues
MNNQGVMILGDLQTIREELSIRDIWEARKRIVSIVNKTPLIQSFVLSEKAGRPVYLKLENVHDIGAFKVRGAANKILSLS
EDEKKKGVATFSTGNHGMAVAYVAKSLGINAVVCISNRVPEAKLESLRRLNAQIEIYGHSQDDAEEYCYHLAEKKGLTII
PPFDDPHIIAGQGTIGLEIVEDVPHVTDVIVPLSGGGLLSGIGLALKSIDPNIRVIGVSAEHAPVMYESLKARKAVKIEE
RDTLADSLLGGIGMDNQYTLQMVGQYTDDILLISEEEIAYSMAFMMDKHHMIIEGAAATGVAAVLENKLPRHDGAIVIVI
SGHNVDLSVLFQLIQRYNDLSH
>Mature_342_residues
MNNQGVMILGDLQTIREELSIRDIWEARKRIVSIVNKTPLIQSFVLSEKAGRPVYLKLENVHDIGAFKVRGAANKILSLS
EDEKKKGVATFSTGNHGMAVAYVAKSLGINAVVCISNRVPEAKLESLRRLNAQIEIYGHSQDDAEEYCYHLAEKKGLTII
PPFDDPHIIAGQGTIGLEIVEDVPHVTDVIVPLSGGGLLSGIGLALKSIDPNIRVIGVSAEHAPVMYESLKARKAVKIEE
RDTLADSLLGGIGMDNQYTLQMVGQYTDDILLISEEEIAYSMAFMMDKHHMIIEGAAATGVAAVLENKLPRHDGAIVIVI
SGHNVDLSVLFQLIQRYNDLSH

Specific function: Acts On Both Serine And Threonine, And Properly Considered As A Hydroxy Amino Acid Deaminase. [C]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=318, Percent_Identity=33.3333333333333, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI33469958, Length=325, Percent_Identity=28.6153846153846, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI19923959, Length=304, Percent_Identity=26.9736842105263, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789505, Length=317, Percent_Identity=39.1167192429022, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1790207, Length=312, Percent_Identity=27.8846153846154, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71991565, Length=321, Percent_Identity=33.6448598130841, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17537387, Length=319, Percent_Identity=33.2288401253918, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17508781, Length=314, Percent_Identity=27.3885350318471, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322631, Length=321, Percent_Identity=35.5140186915888, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6320930, Length=337, Percent_Identity=32.0474777448071, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6319788, Length=315, Percent_Identity=26.984126984127, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21355833, Length=322, Percent_Identity=32.6086956521739, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24645328, Length=219, Percent_Identity=31.9634703196347, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014333
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 37351; Mature: 37351

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQGVMILGDLQTIREELSIRDIWEARKRIVSIVNKTPLIQSFVLSEKAGRPVYLKLEN
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECC
VHDIGAFKVRGAANKILSLSEDEKKKGVATFSTGNHGMAVAYVAKSLGINAVVCISNRVP
CCCCCCEEECCCHHHHEECCCCHHHCCEEEEECCCCCEEHEEHHHHCCCEEEEEECCCCC
EAKLESLRRLNAQIEIYGHSQDDAEEYCYHLAEKKGLTIIPPFDDPHIIAGQGTIGLEIV
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCCEEEECCCCCCCHHH
EDVPHVTDVIVPLSGGGLLSGIGLALKSIDPNIRVIGVSAEHAPVMYESLKARKAVKIEE
HCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCEEECH
RDTLADSLLGGIGMDNQYTLQMVGQYTDDILLISEEEIAYSMAFMMDKHHMIIEGAAATG
HHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEECHHHHHHHHHHHCCCEEEEECCHHHH
VAAVLENKLPRHDGAIVIVISGHNVDLSVLFQLIQRYNDLSH
HHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNQGVMILGDLQTIREELSIRDIWEARKRIVSIVNKTPLIQSFVLSEKAGRPVYLKLEN
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECC
VHDIGAFKVRGAANKILSLSEDEKKKGVATFSTGNHGMAVAYVAKSLGINAVVCISNRVP
CCCCCCEEECCCHHHHEECCCCHHHCCEEEEECCCCCEEHEEHHHHCCCEEEEEECCCCC
EAKLESLRRLNAQIEIYGHSQDDAEEYCYHLAEKKGLTIIPPFDDPHIIAGQGTIGLEIV
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCCEEEECCCCCCCHHH
EDVPHVTDVIVPLSGGGLLSGIGLALKSIDPNIRVIGVSAEHAPVMYESLKARKAVKIEE
HCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCEEECH
RDTLADSLLGGIGMDNQYTLQMVGQYTDDILLISEEEIAYSMAFMMDKHHMIIEGAAATG
HHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEECHHHHHHHHHHHCCCEEEEECCHHHH
VAAVLENKLPRHDGAIVIVISGHNVDLSVLFQLIQRYNDLSH
HHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]