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The map label for this gene is ribD [H]

Identifier: 138895866

GI number: 138895866

Start: 2347673

End: 2348752

Strand: Reverse

Name: ribD [H]

Synonym: GTNG_2225

Alternate gene names: 138895866

Gene position: 2348752-2347673 (Counterclockwise)

Preceding gene: 138895868

Following gene: 138895865

Centisome position: 66.16

GC content: 55.65

Gene sequence:

>1080_bases
ATGCGGTTAGCGCTTGATGTAGCCAAGGCCGGAGTTGGGCAAACGTCCCCCAATCCTGCTGTCGGTGCCGTCGTCGTCAA
CGACGGTACGATTGTCGGAATTGGCGCCCACTTAAAAGCAGGAGAGCCGCACGCCGAGGTGCATGCGATCCGCATGGCCG
GTGAAAAGGCGCGCGGGGCAACGGTATATGTGACGCTTGAGCCATGCAGCCATTATGGCAAAACGCCACCATGCGCTGAT
TTGCTCATTGAAGCCGGCGTCCGCCGTGTCGTCGTTGCGACGACCGATCCGAATCCGCTTGTTGCTGGGAAAGGAATTAA
TAAGCTGCGTCGGGCGGGCATTGACGTGGAGGTTGGAATATTAAAAGAAGAAGCGGATGAGTTAAACCGCATGTTTTTCC
ATTATATTGCGACGAAAACGCCGTTTGTAACGATCAAATATGCGTGCAGCCTCGACGGCAAAATCGCCACGGCGACAGGG
GAGAGCAAATGGATCACATCCAGTGCAGCGCGTGAGGATGTTCATCGTCTCCGTGCGCAACATGACGCTATTTTAGTTGG
CGTTAACACCGTGATGGCGGATAACCCGAAGCTGACGGTCCGCATTGGGCAACAGCGGAAAAACCCCCTTCGGGTCATTT
TGGATACCAACTTGCATACACCGCTCGACGCCCATGTTGTCGTCGACAAGGAAGCAGAAACGTGGATCATCACTGGCAGC
GGTGTCAGCCGGGAAAAAGCGAAGATGTATGAGCGCCTTGGGGTGCGCATCGTGCCGATGACAAGCGCACACATTGATGT
GCGCGAGGTGCTCCGCCTGCTTGGTGAGCAGCGTATCACGTCATTGTTTGTTGAGGGAGGCTCGCGAATTCATGACAGCT
TCCTTCGCTCCGGGATGGTCAATGAAGTCGTTGCCTATATGGCTCCGAAACTAATCGGCGGCCGCGAAGCGCCGACGCCG
GTCGGCGGTCTCGGTTTCTCGCGTCTCGCTGAAGCGATGGAGCTTGACATCCGGCAGATTGAGAAAATCGGTCCGGATAT
CAAGATCGTCGCTAAACCGATCAAGAAGGAGGAGTCGTGA

Upstream 100 bases:

>100_bases
CATCCTGACCCATTCTCTCACGTCTTAGAGCCCCGGAATATTTCCGGGGTTTTTATTTTGTAGGAAAAAGGTGGATACCG
TGTACAATGATGAACATTAC

Downstream 100 bases:

>100_bases
TGTTCACCGGTATTATTGAAGAGATCGGCACGGTTGAACAAATGAGGCAAACAGGCAGCGCCATTGTGATGACGATTGGC
GCCAAGCGGGTGCTTGAAGA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRLALDVAKAGVGQTSPNPAVGAVVVNDGTIVGIGAHLKAGEPHAEVHAIRMAGEKARGATVYVTLEPCSHYGKTPPCAD
LLIEAGVRRVVVATTDPNPLVAGKGINKLRRAGIDVEVGILKEEADELNRMFFHYIATKTPFVTIKYACSLDGKIATATG
ESKWITSSAAREDVHRLRAQHDAILVGVNTVMADNPKLTVRIGQQRKNPLRVILDTNLHTPLDAHVVVDKEAETWIITGS
GVSREKAKMYERLGVRIVPMTSAHIDVREVLRLLGEQRITSLFVEGGSRIHDSFLRSGMVNEVVAYMAPKLIGGREAPTP
VGGLGFSRLAEAMELDIRQIEKIGPDIKIVAKPIKKEES

Sequences:

>Translated_359_residues
MRLALDVAKAGVGQTSPNPAVGAVVVNDGTIVGIGAHLKAGEPHAEVHAIRMAGEKARGATVYVTLEPCSHYGKTPPCAD
LLIEAGVRRVVVATTDPNPLVAGKGINKLRRAGIDVEVGILKEEADELNRMFFHYIATKTPFVTIKYACSLDGKIATATG
ESKWITSSAAREDVHRLRAQHDAILVGVNTVMADNPKLTVRIGQQRKNPLRVILDTNLHTPLDAHVVVDKEAETWIITGS
GVSREKAKMYERLGVRIVPMTSAHIDVREVLRLLGEQRITSLFVEGGSRIHDSFLRSGMVNEVVAYMAPKLIGGREAPTP
VGGLGFSRLAEAMELDIRQIEKIGPDIKIVAKPIKKEES
>Mature_359_residues
MRLALDVAKAGVGQTSPNPAVGAVVVNDGTIVGIGAHLKAGEPHAEVHAIRMAGEKARGATVYVTLEPCSHYGKTPPCAD
LLIEAGVRRVVVATTDPNPLVAGKGINKLRRAGIDVEVGILKEEADELNRMFFHYIATKTPFVTIKYACSLDGKIATATG
ESKWITSSAAREDVHRLRAQHDAILVGVNTVMADNPKLTVRIGQQRKNPLRVILDTNLHTPLDAHVVVDKEAETWIITGS
GVSREKAKMYERLGVRIVPMTSAHIDVREVLRLLGEQRITSLFVEGGSRIHDSFLRSGMVNEVVAYMAPKLIGGREAPTP
VGGLGFSRLAEAMELDIRQIEKIGPDIKIVAKPIKKEES

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=360, Percent_Identity=45.8333333333333, Blast_Score=315, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6319629, Length=195, Percent_Identity=30.2564102564103, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 38796; Mature: 38796

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLALDVAKAGVGQTSPNPAVGAVVVNDGTIVGIGAHLKAGEPHAEVHAIRMAGEKARGA
CCEEEEHHHCCCCCCCCCCCEEEEEEECCEEEEECCEECCCCCCHHEEEEEECCCCCCCC
TVYVTLEPCSHYGKTPPCADLLIEAGVRRVVVATTDPNPLVAGKGINKLRRAGIDVEVGI
EEEEEECCHHCCCCCCCHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHCCCCEEEEE
LKEEADELNRMFFHYIATKTPFVTIKYACSLDGKIATATGESKWITSSAAREDVHRLRAQ
EHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEECCCCCEEEHHHHHHHHHHHHHC
HDAILVGVNTVMADNPKLTVRIGQQRKNPLRVILDTNLHTPLDAHVVVDKEAETWIITGS
CCEEEEEEEEEEECCCEEEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCEEEEECC
GVSREKAKMYERLGVRIVPMTSAHIDVREVLRLLGEQRITSLFVEGGSRIHDSFLRSGMV
CCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHH
NEVVAYMAPKLIGGREAPTPVGGLGFSRLAEAMELDIRQIEKIGPDIKIVAKPIKKEES
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRLALDVAKAGVGQTSPNPAVGAVVVNDGTIVGIGAHLKAGEPHAEVHAIRMAGEKARGA
CCEEEEHHHCCCCCCCCCCCEEEEEEECCEEEEECCEECCCCCCHHEEEEEECCCCCCCC
TVYVTLEPCSHYGKTPPCADLLIEAGVRRVVVATTDPNPLVAGKGINKLRRAGIDVEVGI
EEEEEECCHHCCCCCCCHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHCCCCEEEEE
LKEEADELNRMFFHYIATKTPFVTIKYACSLDGKIATATGESKWITSSAAREDVHRLRAQ
EHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEECCCCCEEEHHHHHHHHHHHHHC
HDAILVGVNTVMADNPKLTVRIGQQRKNPLRVILDTNLHTPLDAHVVVDKEAETWIITGS
CCEEEEEEEEEEECCCEEEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCEEEEECC
GVSREKAKMYERLGVRIVPMTSAHIDVREVLRLLGEQRITSLFVEGGSRIHDSFLRSGMV
CCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHH
NEVVAYMAPKLIGGREAPTPVGGLGFSRLAEAMELDIRQIEKIGPDIKIVAKPIKKEES
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 2112225; 9068650 [H]