| Definition | Geobacillus thermodenitrificans NG80-2 chromosome, complete genome. |
|---|---|
| Accession | NC_009328 |
| Length | 3,550,319 |
Click here to switch to the map view.
The map label for this gene is ppiB [H]
Identifier: 138895868
GI number: 138895868
Start: 2349291
End: 2349731
Strand: Reverse
Name: ppiB [H]
Synonym: GTNG_2227
Alternate gene names: 138895868
Gene position: 2349731-2349291 (Counterclockwise)
Preceding gene: 138895869
Following gene: 138895866
Centisome position: 66.18
GC content: 51.47
Gene sequence:
>441_bases ATGGCGAAAAAAGGCTATATTTTGATGGAAAATGGCGGAAAGATTGAATTTGAACTGTTTCCAAATGAGGCGCCGGTGAC GGTGGCCAACTTTGAAAAATTAGCGAACGAAGGGTTTTATAATGGACTGACGTTTCACCGTGTCATCCCTGGTTTTGTCA GCCAAGGCGGTTGTCCGCGCGGCAATGGAACGGGCGATGCTGGTTACACAATCCCATGCGAGACAGACAATAATCCGCAC CGGCATGTCACCGGAGCGATTTCGATGGCGCACCGCGGCCGCGATACTGGCAGCTGCCAGTTTTTCATCGTCCATGAACC GCAGCCGCATCTAGACGGGGTGCACACCGTCTTCGGACAAGTCACGTCCGGAATGGATGTCGTCAAAGCGATGAAAAACG GTGATGTGATGAAGGAAGTGAAAGTGGTTGACGAACCGTAA
Upstream 100 bases:
>100_bases ACATGGAACATTTGGATGAAAAGGCATTTTGGCTTTCTTTCTGTTGGTCAATCATGGTATGATAAAGACAGTTTATGCGT GAAAAAGGAGGGGAAGCGCG
Downstream 100 bases:
>100_bases GCAGCGGACGGAAGATGGAGAACGGACAAGCCGAACGAATTGGCTTTTGTTTTTCATCTTGTTGGCGGCTAGTTTCATAT GGGGAGCCGTGTATTGGCTT
Product: peptidyl-prolyl cis-trans isomerase B
Products: NA
Alternate protein names: PPIase B; Rotamase B [H]
Number of amino acids: Translated: 146; Mature: 145
Protein sequence:
>146_residues MAKKGYILMENGGKIEFELFPNEAPVTVANFEKLANEGFYNGLTFHRVIPGFVSQGGCPRGNGTGDAGYTIPCETDNNPH RHVTGAISMAHRGRDTGSCQFFIVHEPQPHLDGVHTVFGQVTSGMDVVKAMKNGDVMKEVKVVDEP
Sequences:
>Translated_146_residues MAKKGYILMENGGKIEFELFPNEAPVTVANFEKLANEGFYNGLTFHRVIPGFVSQGGCPRGNGTGDAGYTIPCETDNNPH RHVTGAISMAHRGRDTGSCQFFIVHEPQPHLDGVHTVFGQVTSGMDVVKAMKNGDVMKEVKVVDEP >Mature_145_residues AKKGYILMENGGKIEFELFPNEAPVTVANFEKLANEGFYNGLTFHRVIPGFVSQGGCPRGNGTGDAGYTIPCETDNNPHR HVTGAISMAHRGRDTGSCQFFIVHEPQPHLDGVHTVFGQVTSGMDVVKAMKNGDVMKEVKVVDEP
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI10863927, Length=143, Percent_Identity=41.958041958042, Blast_Score=95, Evalue=2e-20, Organism=Homo sapiens, GI7706339, Length=136, Percent_Identity=40.4411764705882, Blast_Score=95, Evalue=3e-20, Organism=Homo sapiens, GI24308049, Length=135, Percent_Identity=45.1851851851852, Blast_Score=94, Evalue=3e-20, Organism=Homo sapiens, GI310127646, Length=144, Percent_Identity=39.5833333333333, Blast_Score=87, Evalue=4e-18, Organism=Homo sapiens, GI310114371, Length=144, Percent_Identity=39.5833333333333, Blast_Score=87, Evalue=4e-18, Organism=Homo sapiens, GI310119221, Length=144, Percent_Identity=39.5833333333333, Blast_Score=87, Evalue=4e-18, Organism=Homo sapiens, GI19557636, Length=123, Percent_Identity=39.0243902439024, Blast_Score=86, Evalue=9e-18, Organism=Homo sapiens, GI6631100, Length=135, Percent_Identity=40.7407407407407, Blast_Score=86, Evalue=1e-17, Organism=Homo sapiens, GI256017253, Length=143, Percent_Identity=37.7622377622378, Blast_Score=85, Evalue=2e-17, Organism=Homo sapiens, GI221139811, Length=143, Percent_Identity=37.7622377622378, Blast_Score=85, Evalue=2e-17, Organism=Homo sapiens, GI256017251, Length=143, Percent_Identity=37.7622377622378, Blast_Score=85, Evalue=2e-17, Organism=Homo sapiens, GI4826932, Length=144, Percent_Identity=39.5833333333333, Blast_Score=85, Evalue=2e-17, Organism=Homo sapiens, GI209417936, Length=143, Percent_Identity=37.7622377622378, Blast_Score=85, Evalue=3e-17, Organism=Homo sapiens, GI30102944, Length=143, Percent_Identity=37.7622377622378, Blast_Score=85, Evalue=3e-17, Organism=Homo sapiens, GI219842199, Length=143, Percent_Identity=37.7622377622378, Blast_Score=85, Evalue=3e-17, Organism=Homo sapiens, GI310129267, Length=143, Percent_Identity=38.4615384615385, Blast_Score=84, Evalue=3e-17, Organism=Homo sapiens, GI310120620, Length=143, Percent_Identity=38.4615384615385, Blast_Score=84, Evalue=3e-17, Organism=Homo sapiens, GI42560244, Length=136, Percent_Identity=40.4411764705882, Blast_Score=83, Evalue=7e-17, Organism=Homo sapiens, GI4758950, Length=131, Percent_Identity=42.7480916030534, Blast_Score=83, Evalue=8e-17, Organism=Homo sapiens, GI150418007, Length=144, Percent_Identity=38.8888888888889, Blast_Score=83, Evalue=9e-17, Organism=Homo sapiens, GI178057341, Length=143, Percent_Identity=37.0629370629371, Blast_Score=82, Evalue=1e-16, Organism=Homo sapiens, GI310110104, Length=143, Percent_Identity=38.4615384615385, Blast_Score=82, Evalue=2e-16, Organism=Homo sapiens, GI5454154, Length=132, Percent_Identity=39.3939393939394, Blast_Score=80, Evalue=6e-16, Organism=Homo sapiens, GI5031987, Length=143, Percent_Identity=40.5594405594406, Blast_Score=79, Evalue=1e-15, Organism=Homo sapiens, GI64276486, Length=119, Percent_Identity=36.1344537815126, Blast_Score=79, Evalue=1e-15, Organism=Homo sapiens, GI310114540, Length=141, Percent_Identity=39.7163120567376, Blast_Score=79, Evalue=1e-15, Organism=Homo sapiens, GI310127745, Length=141, Percent_Identity=39.7163120567376, Blast_Score=79, Evalue=2e-15, Organism=Homo sapiens, GI310119290, Length=141, Percent_Identity=39.7163120567376, Blast_Score=79, Evalue=2e-15, Organism=Homo sapiens, GI169214050, Length=143, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=5e-15, Organism=Homo sapiens, GI169164185, Length=143, Percent_Identity=37.0629370629371, Blast_Score=77, Evalue=6e-15, Organism=Homo sapiens, GI169163623, Length=143, Percent_Identity=37.0629370629371, Blast_Score=77, Evalue=6e-15, Organism=Homo sapiens, GI239751853, Length=143, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=6e-15, Organism=Homo sapiens, GI113428306, Length=143, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=6e-15, Organism=Homo sapiens, GI4505991, Length=127, Percent_Identity=43.3070866141732, Blast_Score=77, Evalue=6e-15, Organism=Homo sapiens, GI169163387, Length=143, Percent_Identity=37.0629370629371, Blast_Score=76, Evalue=9e-15, Organism=Homo sapiens, GI5174637, Length=144, Percent_Identity=36.1111111111111, Blast_Score=75, Evalue=1e-14, Organism=Homo sapiens, GI22547212, Length=135, Percent_Identity=40.7407407407407, Blast_Score=75, Evalue=2e-14, Organism=Homo sapiens, GI7657473, Length=135, Percent_Identity=40.7407407407407, Blast_Score=75, Evalue=2e-14, Organism=Homo sapiens, GI45439316, Length=141, Percent_Identity=35.4609929078014, Blast_Score=75, Evalue=2e-14, Organism=Homo sapiens, GI310132444, Length=143, Percent_Identity=36.3636363636364, Blast_Score=75, Evalue=2e-14, Organism=Homo sapiens, GI310113152, Length=143, Percent_Identity=36.3636363636364, Blast_Score=75, Evalue=2e-14, Organism=Homo sapiens, GI303305009, Length=127, Percent_Identity=37.7952755905512, Blast_Score=75, Evalue=3e-14, Organism=Homo sapiens, GI22547215, Length=135, Percent_Identity=40.7407407407407, Blast_Score=75, Evalue=3e-14, Organism=Homo sapiens, GI20911035, Length=145, Percent_Identity=33.7931034482759, Blast_Score=72, Evalue=2e-13, Organism=Escherichia coli, GI1789763, Length=147, Percent_Identity=40.1360544217687, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1786736, Length=132, Percent_Identity=35.6060606060606, Blast_Score=63, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17539496, Length=135, Percent_Identity=42.962962962963, Blast_Score=105, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17551282, Length=148, Percent_Identity=43.2432432432432, Blast_Score=90, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17551284, Length=148, Percent_Identity=43.2432432432432, Blast_Score=90, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17506311, Length=130, Percent_Identity=43.8461538461538, Blast_Score=88, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17506307, Length=143, Percent_Identity=44.0559440559441, Blast_Score=83, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17552780, Length=127, Percent_Identity=44.8818897637795, Blast_Score=82, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71997782, Length=122, Percent_Identity=39.344262295082, Blast_Score=81, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17565860, Length=153, Percent_Identity=38.562091503268, Blast_Score=80, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17532641, Length=128, Percent_Identity=34.375, Blast_Score=80, Evalue=4e-16, Organism=Caenorhabditis elegans, GI71980590, Length=128, Percent_Identity=35.15625, Blast_Score=79, Evalue=6e-16, Organism=Caenorhabditis elegans, GI71980594, Length=128, Percent_Identity=35.15625, Blast_Score=79, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17539498, Length=127, Percent_Identity=40.9448818897638, Blast_Score=79, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17559074, Length=150, Percent_Identity=36.6666666666667, Blast_Score=77, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17552782, Length=139, Percent_Identity=38.8489208633094, Blast_Score=77, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17532643, Length=133, Percent_Identity=38.3458646616541, Blast_Score=74, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17566266, Length=133, Percent_Identity=36.8421052631579, Blast_Score=71, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17552784, Length=137, Percent_Identity=32.8467153284672, Blast_Score=66, Evalue=7e-12, Organism=Saccharomyces cerevisiae, GI6323562, Length=127, Percent_Identity=44.8818897637795, Blast_Score=92, Evalue=3e-20, Organism=Saccharomyces cerevisiae, GI6321848, Length=133, Percent_Identity=44.3609022556391, Blast_Score=83, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6320359, Length=127, Percent_Identity=42.5196850393701, Blast_Score=82, Evalue=3e-17, Organism=Saccharomyces cerevisiae, GI6320510, Length=129, Percent_Identity=40.3100775193798, Blast_Score=77, Evalue=7e-16, Organism=Saccharomyces cerevisiae, GI6323246, Length=142, Percent_Identity=38.0281690140845, Blast_Score=74, Evalue=1e-14, Organism=Drosophila melanogaster, GI19922376, Length=138, Percent_Identity=39.8550724637681, Blast_Score=99, Evalue=6e-22, Organism=Drosophila melanogaster, GI17986117, Length=135, Percent_Identity=41.4814814814815, Blast_Score=98, Evalue=2e-21, Organism=Drosophila melanogaster, GI24650807, Length=135, Percent_Identity=41.4814814814815, Blast_Score=91, Evalue=2e-19, Organism=Drosophila melanogaster, GI20130249, Length=131, Percent_Identity=43.5114503816794, Blast_Score=91, Evalue=2e-19, Organism=Drosophila melanogaster, GI21357249, Length=122, Percent_Identity=36.8852459016393, Blast_Score=84, Evalue=2e-17, Organism=Drosophila melanogaster, GI17136360, Length=130, Percent_Identity=41.5384615384615, Blast_Score=80, Evalue=4e-16, Organism=Drosophila melanogaster, GI19922912, Length=130, Percent_Identity=40.7692307692308, Blast_Score=79, Evalue=7e-16, Organism=Drosophila melanogaster, GI45549139, Length=144, Percent_Identity=38.1944444444444, Blast_Score=76, Evalue=8e-15, Organism=Drosophila melanogaster, GI24586038, Length=132, Percent_Identity=36.3636363636364, Blast_Score=75, Evalue=2e-14, Organism=Drosophila melanogaster, GI24664125, Length=146, Percent_Identity=37.6712328767123, Blast_Score=74, Evalue=4e-14, Organism=Drosophila melanogaster, GI21357783, Length=146, Percent_Identity=37.6712328767123, Blast_Score=74, Evalue=4e-14, Organism=Drosophila melanogaster, GI17647301, Length=128, Percent_Identity=39.0625, Blast_Score=73, Evalue=7e-14, Organism=Drosophila melanogaster, GI24652460, Length=130, Percent_Identity=32.3076923076923, Blast_Score=72, Evalue=1e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 15848; Mature: 15717
Theoretical pI: Translated: 6.39; Mature: 6.39
Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.1 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 6.2 %Cys+Met (Translated Protein) 2.1 %Cys (Mature Protein) 3.4 %Met (Mature Protein) 5.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKKGYILMENGGKIEFELFPNEAPVTVANFEKLANEGFYNGLTFHRVIPGFVSQGGCPR CCCCCEEEEECCCEEEEEECCCCCCEEHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCC GNGTGDAGYTIPCETDNNPHRHVTGAISMAHRGRDTGSCQFFIVHEPQPHLDGVHTVFGQ CCCCCCCCEEEECCCCCCCCEEEEHEEHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHH VTSGMDVVKAMKNGDVMKEVKVVDEP HHCCHHHHHHHHCCCCEEEEEECCCC >Mature Secondary Structure AKKGYILMENGGKIEFELFPNEAPVTVANFEKLANEGFYNGLTFHRVIPGFVSQGGCPR CCCCEEEEECCCEEEEEECCCCCCEEHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCC GNGTGDAGYTIPCETDNNPHRHVTGAISMAHRGRDTGSCQFFIVHEPQPHLDGVHTVFGQ CCCCCCCCEEEECCCCCCCCEEEEHEEHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHH VTSGMDVVKAMKNGDVMKEVKVVDEP HHCCHHHHHHHHCCCCEEEEEECCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7934829; 8022278; 9384377; 8755892 [H]