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The map label for this gene is ribH [H]

Identifier: 138895863

GI number: 138895863

Start: 2345330

End: 2345794

Strand: Reverse

Name: ribH [H]

Synonym: GTNG_2222

Alternate gene names: 138895863

Gene position: 2345794-2345330 (Counterclockwise)

Preceding gene: 138895864

Following gene: 138895862

Centisome position: 66.07

GC content: 53.98

Gene sequence:

>465_bases
ATGAACGTCATCGAAGGAAATTTAGTCGGCACCGGGTTGAAAATTGGTATCGTCGTCTCGCGCTTTAACGAATTTATTAC
GAGCAAGCTCTTATCTGGTGCAATCGACGGGTTGACGCGCCATGGCGTCAGCGACAACGATATCACCGTCACATGGGTGC
CGGGGGCGTTTGAAATTCCGCTTGTGGCGAAAAAAATGGCTGAATCAAAGCAATTTGACGCTATCATTACGCTTGGCGCC
GTCATTCGCGGTGCGACGAGCCATTTTGACTACGTGTGCAGCGAGGCAGCCAAAGGCGTCTCCCATGCCGCGCTTACAAG
CGGCGTCCCGGTTATTTTCGGCGTTTTGACAACCGATACGATCGAGCAGGCGATCGAGCGGGCCGGCACAAAAGCGGGCA
ATAAAGGATGGGAGGCGGCTGTTTCCGCGATCGAAATGGCGAACGTTTTACGGGGGCTTGCGTAA

Upstream 100 bases:

>100_bases
CGCTTCAAATGCCACCGACGAAGGAAAACGAAAAATATTTGCGCACGAAATATGAAAAATTAGGACATATGCTTCATTTT
TAATGAAAGGGGAAAGAAAC

Downstream 100 bases:

>100_bases
TTTGTGTAAAAAGGCATGAAATGGTTCACAATATCGGTGAGAATGTTTATAATACGTATAGAGAAAATGACAAAAACTTT
TCCATTTCGGAAAAGCGCTT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MNVIEGNLVGTGLKIGIVVSRFNEFITSKLLSGAIDGLTRHGVSDNDITVTWVPGAFEIPLVAKKMAESKQFDAIITLGA
VIRGATSHFDYVCSEAAKGVSHAALTSGVPVIFGVLTTDTIEQAIERAGTKAGNKGWEAAVSAIEMANVLRGLA

Sequences:

>Translated_154_residues
MNVIEGNLVGTGLKIGIVVSRFNEFITSKLLSGAIDGLTRHGVSDNDITVTWVPGAFEIPLVAKKMAESKQFDAIITLGA
VIRGATSHFDYVCSEAAKGVSHAALTSGVPVIFGVLTTDTIEQAIERAGTKAGNKGWEAAVSAIEMANVLRGLA
>Mature_154_residues
MNVIEGNLVGTGLKIGIVVSRFNEFITSKLLSGAIDGLTRHGVSDNDITVTWVPGAFEIPLVAKKMAESKQFDAIITLGA
VIRGATSHFDYVCSEAAKGVSHAALTSGVPVIFGVLTTDTIEQAIERAGTKAGNKGWEAAVSAIEMANVLRGLA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=154, Percent_Identity=56.4935064935065, Blast_Score=182, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324429, Length=147, Percent_Identity=34.0136054421769, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16056; Mature: 16056

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIEGNLVGTGLKIGIVVSRFNEFITSKLLSGAIDGLTRHGVSDNDITVTWVPGAFEIP
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEECH
LVAKKMAESKQFDAIITLGAVIRGATSHFDYVCSEAAKGVSHAALTSGVPVIFGVLTTDT
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHH
IEQAIERAGTKAGNKGWEAAVSAIEMANVLRGLA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVIEGNLVGTGLKIGIVVSRFNEFITSKLLSGAIDGLTRHGVSDNDITVTWVPGAFEIP
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEECH
LVAKKMAESKQFDAIITLGAVIRGATSHFDYVCSEAAKGVSHAALTSGVPVIFGVLTTDT
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHH
IEQAIERAGTKAGNKGWEAAVSAIEMANVLRGLA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA