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The map label for this gene is resD [H]

Identifier: 138895848

GI number: 138895848

Start: 2331919

End: 2332644

Strand: Reverse

Name: resD [H]

Synonym: GTNG_2207

Alternate gene names: 138895848

Gene position: 2332644-2331919 (Counterclockwise)

Preceding gene: 138895849

Following gene: 138895847

Centisome position: 65.7

GC content: 48.9

Gene sequence:

>726_bases
ATGGAAAAACAAGAAAAACCAATCCACATTTTAGTTGTCGATGATGAAGAACGGATTCGCCGGCTGTTGAAAATGTATTT
AGAGCGGGAAAACTATGTGATCGATGAAGCTGGCGACGGCAATGTAGCGCTTGAGAAAGCGCTGGCGAACGACTATGACG
TCATTTTGCTCGATTTAATGCTGCCGGGCAAAGATGGAATTGAGGTGTGCAAAGAAATTCGCGAGCACAAAACGACACCG
ATTATTATGCTGACGGCGAAAGGAGAAGAATCGAACCGCGTTCAAGGGTTTGAAGTTGGCACCGATGATTACATCGTCAA
GCCGTTCAGTCCACGCGAAGTCGTCTTGCGCGTTAAAGCATTGTTGCGCCGTGCGGCGAATGCCACCTACGCACCGGTGG
AGACGACGACGAAAGATGTGTTGGTGTTTCCACACTTAACGATTGACAATGATGCCCATCGGGTGACGGTCGATGGAAAA
GAAGTGAGCTTGACGCCGAAAGAATACGAGTTGCTTCTCTTTTTAGCGCGCTCGCCAGATAAAGTGTTTGATCGTGAGCA
GCTGCTAAAAGAAGTATGGCATTACGAGTTTTTTGGCGATTTGCGCACCGTCGACACTCATATTAAGCGGTTGCGCGAAA
AGCTCAATAAGGCGTCGCCGCAAGCCGGAAAAATGATCGTCACCGTTTGGGGCGTCGGCTACAAGTTTGAGGCAGTGAGC
GAATGA

Upstream 100 bases:

>100_bases
CTGATCGCAAGGCAAACGGATGCTCTATTGGCGAGCATCCGTTTTTTCAGTAAACTAGAAAGTGGGGATTGTTTCCATCT
TGTGAGGAAGGGTGTTTGAC

Downstream 100 bases:

>100_bases
TGTGGCTGTTTCGCAGTGTCGTTGGGAAACTATGGTTTACCATTTTGCTGCTCGTCTCATGCGTGTTGTTTATTTTAACC
ATTTTGCTTATTAAATTTTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MEKQEKPIHILVVDDEERIRRLLKMYLERENYVIDEAGDGNVALEKALANDYDVILLDLMLPGKDGIEVCKEIREHKTTP
IIMLTAKGEESNRVQGFEVGTDDYIVKPFSPREVVLRVKALLRRAANATYAPVETTTKDVLVFPHLTIDNDAHRVTVDGK
EVSLTPKEYELLLFLARSPDKVFDREQLLKEVWHYEFFGDLRTVDTHIKRLREKLNKASPQAGKMIVTVWGVGYKFEAVS
E

Sequences:

>Translated_241_residues
MEKQEKPIHILVVDDEERIRRLLKMYLERENYVIDEAGDGNVALEKALANDYDVILLDLMLPGKDGIEVCKEIREHKTTP
IIMLTAKGEESNRVQGFEVGTDDYIVKPFSPREVVLRVKALLRRAANATYAPVETTTKDVLVFPHLTIDNDAHRVTVDGK
EVSLTPKEYELLLFLARSPDKVFDREQLLKEVWHYEFFGDLRTVDTHIKRLREKLNKASPQAGKMIVTVWGVGYKFEAVS
E
>Mature_241_residues
MEKQEKPIHILVVDDEERIRRLLKMYLERENYVIDEAGDGNVALEKALANDYDVILLDLMLPGKDGIEVCKEIREHKTTP
IIMLTAKGEESNRVQGFEVGTDDYIVKPFSPREVVLRVKALLRRAANATYAPVETTTKDVLVFPHLTIDNDAHRVTVDGK
EVSLTPKEYELLLFLARSPDKVFDREQLLKEVWHYEFFGDLRTVDTHIKRLREKLNKASPQAGKMIVTVWGVGYKFEAVS
E

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=40.4347826086956, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=43.9130434782609, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI87082012, Length=234, Percent_Identity=38.4615384615385, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=35.0877192982456, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=37.5, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=36.3636363636364, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=33.6244541484716, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=35.8078602620087, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=34.3347639484979, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI2367329, Length=206, Percent_Identity=37.378640776699, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=33.4763948497854, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=34.7639484978541, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=31.304347826087, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=29.8701298701299, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=37.3913043478261, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788191, Length=111, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=35.6521739130435, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788521, Length=223, Percent_Identity=28.6995515695067, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27680; Mature: 27680

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQEKPIHILVVDDEERIRRLLKMYLERENYVIDEAGDGNVALEKALANDYDVILLDLM
CCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCEEEEEEE
LPGKDGIEVCKEIREHKTTPIIMLTAKGEESNRVQGFEVGTDDYIVKPFSPREVVLRVKA
CCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHH
LLRRAANATYAPVETTTKDVLVFPHLTIDNDAHRVTVDGKEVSLTPKEYELLLFLARSPD
HHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCCEEEECCCCEEEEEEEECCCH
KVFDREQLLKEVWHYEFFGDLRTVDTHIKRLREKLNKASPQAGKMIVTVWGVGYKFEAVS
HHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECC
E
C
>Mature Secondary Structure
MEKQEKPIHILVVDDEERIRRLLKMYLERENYVIDEAGDGNVALEKALANDYDVILLDLM
CCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCEEEEEEE
LPGKDGIEVCKEIREHKTTPIIMLTAKGEESNRVQGFEVGTDDYIVKPFSPREVVLRVKA
CCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHH
LLRRAANATYAPVETTTKDVLVFPHLTIDNDAHRVTVDGKEVSLTPKEYELLLFLARSPD
HHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCCEEEECCCCEEEEEEEECCCH
KVFDREQLLKEVWHYEFFGDLRTVDTHIKRLREKLNKASPQAGKMIVTVWGVGYKFEAVS
HHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]