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The map label for this gene is resE [H]

Identifier: 138895847

GI number: 138895847

Start: 2330126

End: 2331922

Strand: Reverse

Name: resE [H]

Synonym: GTNG_2206

Alternate gene names: 138895847

Gene position: 2331922-2330126 (Counterclockwise)

Preceding gene: 138895848

Following gene: 138895846

Centisome position: 65.68

GC content: 51.47

Gene sequence:

>1797_bases
ATGATGTGGCTGTTTCGCAGTGTCGTTGGGAAACTATGGTTTACCATTTTGCTGCTCGTCTCATGCGTGTTGTTTATTTT
AACCATTTTGCTTATTAAATTTTTCGAGGAGTACTATGTACAAGAAGCGGAAAACGATTTAACCCGTCTGGCGACGAAAG
TAGCAGAGGTGATGCACGATTATCGTGACGAGCAGCTTGCCCGTTCGATTGCTTGGACGCTTGTCGACAATCGTTCAAAA
GCGATCATTGTCGCCGATGAGTCGCATTATTGGTATTCGCCTGGCGAGGCAGACTTGAAAGACATGCCACTGTCGTCCAT
CCGTGAAGACTCAGACTTGCGCCGCGTGCTGACTGACCAAGAAACGGTGAAAAAGCGTCTGTATGCGACGGAGTGGGAAC
AAAATGGAAAGCCGCAGCACGATATGATCATCGTCGGCGTGCCGATGTCGATGCCGGACGGCAGCCGCGGTGCCGTTTTC
ATTTACCAGTCGCTCGAGGCGATCGCTGATGCAACCGAACATACAAAAGAGCTCATTTTTCTCGCCGCCTTTATCGCCAT
TGTGATGACGACGTTTTTTGCCTTTTTCTTGTCGACGCGCATTACCGCTCCGCTCAGGAAGATGCGCCAAGCCGCGTTTG
AAGTGGCGCGCGGCCATTTTGACACTAAAGTGCCGATTTTAACGAATGATGAAATCGGCGGGCTGGCGATGGCGTTTAAC
CAAATGGGACGGCGGCTTCAATTTAACATTAACGCATTAAACCAGGAAAAAGAACAACTGGCCAGCATTTTAAGCAGCAT
GGCCGACGGCGTCATTACATTTAGCCGTGAGGGGGAAATATTAATTACGAACCCGCCGGCGGAGCGGTTTTTACAGGCAT
GGTATTTCGAACAAGGAAATGATGCGGAAACGATGGCGCCGCTGCCGCCGCAAGTGAAAGAGCTGTTCGCTCGCGTCGTC
CGGGAGGAAAAGGAGCAATCCACCGAGGTGACGATACAAGGGCGGACATGGGTCATTTTAATGACGCCGTTATACGGCAA
AACGATGGTGCGTGGTGCGGTCGCTGTTTTGCGTGACATGACTGAGGAGCGGAGGCTTGATAAGCTGCGCAAAGATTTTA
TCGCCAACGTCTCGCACGAACTGCGTACGCCGATTGCTATGTTGCAAGGATACAGCGAGGCGATTATCGATGATATTGCT
GCGAGTGAGGAAGAGAAGAAAGAGATGGCAAAAGTCATTTATGACGAGTCGCTGCGCATGGGCCGCCTTGTTAACGATTT
GCTTGATCTCGCGCGTATGGAGGCTGGCCATATCGAGCTGCAATATGAGCAAGTGGAGCTCGTCCCTTACGTGGAACGGG
TGATCCGCAAGTTTTACGGGCTGGCGAAAGAAAAGCAGATCGAGCTGACAGCCGAGTTTCGCGACGAGAACATCGAAATC
GCATTCGATCCAGACCGGATCGAGCAAGTGTTAACCAACTTAATCGATAATGCCATTCGCCATACGGAAGCGGGCGGTAC
GGTCCGTCTAATTATCGAGCGAAGCGGCGACGGCGTGACCATCCACGTCCAAGACTCGGGCTCCGGCATTCCGGAGGAAG
ATTTGCCGTTTGTGTTTGAACGGTTTTATAAAGCTGATAAAGCGCGGACGCGCGGCCGTTCGGGCACCGGACTCGGCTTG
GCTATCGCCAAAAACATCGTGGAAACGCATAAAGGGCGCATTACCGTCCATAGCAAACTGAACGAAGGAACGACGTTTTC
ATTTTATTTGCCGGCTCACGGCCCAAAAGAGATGTAA

Upstream 100 bases:

>100_bases
TTAAGCGGTTGCGCGAAAAGCTCAATAAGGCGTCGCCGCAAGCCGGAAAAATGATCGTCACCGTTTGGGGCGTCGGCTAC
AAGTTTGAGGCAGTGAGCGA

Downstream 100 bases:

>100_bases
CGTCGTGAAAGGAGGCGGATGGCCGCCTCTTTTTTGGTTTAGTGGTATAGACAACTAGAATATATGATGTTATGATTGTG
ATAGAAAGAGAGGGATCGAC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MMWLFRSVVGKLWFTILLLVSCVLFILTILLIKFFEEYYVQEAENDLTRLATKVAEVMHDYRDEQLARSIAWTLVDNRSK
AIIVADESHYWYSPGEADLKDMPLSSIREDSDLRRVLTDQETVKKRLYATEWEQNGKPQHDMIIVGVPMSMPDGSRGAVF
IYQSLEAIADATEHTKELIFLAAFIAIVMTTFFAFFLSTRITAPLRKMRQAAFEVARGHFDTKVPILTNDEIGGLAMAFN
QMGRRLQFNINALNQEKEQLASILSSMADGVITFSREGEILITNPPAERFLQAWYFEQGNDAETMAPLPPQVKELFARVV
REEKEQSTEVTIQGRTWVILMTPLYGKTMVRGAVAVLRDMTEERRLDKLRKDFIANVSHELRTPIAMLQGYSEAIIDDIA
ASEEEKKEMAKVIYDESLRMGRLVNDLLDLARMEAGHIELQYEQVELVPYVERVIRKFYGLAKEKQIELTAEFRDENIEI
AFDPDRIEQVLTNLIDNAIRHTEAGGTVRLIIERSGDGVTIHVQDSGSGIPEEDLPFVFERFYKADKARTRGRSGTGLGL
AIAKNIVETHKGRITVHSKLNEGTTFSFYLPAHGPKEM

Sequences:

>Translated_598_residues
MMWLFRSVVGKLWFTILLLVSCVLFILTILLIKFFEEYYVQEAENDLTRLATKVAEVMHDYRDEQLARSIAWTLVDNRSK
AIIVADESHYWYSPGEADLKDMPLSSIREDSDLRRVLTDQETVKKRLYATEWEQNGKPQHDMIIVGVPMSMPDGSRGAVF
IYQSLEAIADATEHTKELIFLAAFIAIVMTTFFAFFLSTRITAPLRKMRQAAFEVARGHFDTKVPILTNDEIGGLAMAFN
QMGRRLQFNINALNQEKEQLASILSSMADGVITFSREGEILITNPPAERFLQAWYFEQGNDAETMAPLPPQVKELFARVV
REEKEQSTEVTIQGRTWVILMTPLYGKTMVRGAVAVLRDMTEERRLDKLRKDFIANVSHELRTPIAMLQGYSEAIIDDIA
ASEEEKKEMAKVIYDESLRMGRLVNDLLDLARMEAGHIELQYEQVELVPYVERVIRKFYGLAKEKQIELTAEFRDENIEI
AFDPDRIEQVLTNLIDNAIRHTEAGGTVRLIIERSGDGVTIHVQDSGSGIPEEDLPFVFERFYKADKARTRGRSGTGLGL
AIAKNIVETHKGRITVHSKLNEGTTFSFYLPAHGPKEM
>Mature_598_residues
MMWLFRSVVGKLWFTILLLVSCVLFILTILLIKFFEEYYVQEAENDLTRLATKVAEVMHDYRDEQLARSIAWTLVDNRSK
AIIVADESHYWYSPGEADLKDMPLSSIREDSDLRRVLTDQETVKKRLYATEWEQNGKPQHDMIIVGVPMSMPDGSRGAVF
IYQSLEAIADATEHTKELIFLAAFIAIVMTTFFAFFLSTRITAPLRKMRQAAFEVARGHFDTKVPILTNDEIGGLAMAFN
QMGRRLQFNINALNQEKEQLASILSSMADGVITFSREGEILITNPPAERFLQAWYFEQGNDAETMAPLPPQVKELFARVV
REEKEQSTEVTIQGRTWVILMTPLYGKTMVRGAVAVLRDMTEERRLDKLRKDFIANVSHELRTPIAMLQGYSEAIIDDIA
ASEEEKKEMAKVIYDESLRMGRLVNDLLDLARMEAGHIELQYEQVELVPYVERVIRKFYGLAKEKQIELTAEFRDENIEI
AFDPDRIEQVLTNLIDNAIRHTEAGGTVRLIIERSGDGVTIHVQDSGSGIPEEDLPFVFERFYKADKARTRGRSGTGLGL
AIAKNIVETHKGRITVHSKLNEGTTFSFYLPAHGPKEM

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=358, Percent_Identity=31.5642458100559, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1788393, Length=224, Percent_Identity=33.9285714285714, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=35.2422907488987, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=32.7510917030568, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=34.6153846153846, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI48994928, Length=267, Percent_Identity=30.3370786516854, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=28.9473684210526, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI145693157, Length=229, Percent_Identity=29.2576419213974, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=30.4166666666667, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI87081816, Length=236, Percent_Identity=31.3559322033898, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788549, Length=395, Percent_Identity=25.3164556962025, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=28.0701754385965, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=29.4354838709677, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1790861, Length=251, Percent_Identity=29.4820717131474, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=28.3783783783784, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790300, Length=362, Percent_Identity=26.2430939226519, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788279, Length=220, Percent_Identity=30, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789808, Length=256, Percent_Identity=28.125, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787374, Length=264, Percent_Identity=23.8636363636364, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789403, Length=213, Percent_Identity=25.8215962441315, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=248, Percent_Identity=26.6129032258064, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68148; Mature: 68148

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMWLFRSVVGKLWFTILLLVSCVLFILTILLIKFFEEYYVQEAENDLTRLATKVAEVMHD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRDEQLARSIAWTLVDNRSKAIIVADESHYWYSPGEADLKDMPLSSIREDSDLRRVLTDQ
HHHHHHHHHHHHHEEECCCCEEEEEECCCEEECCCCCCCCCCCHHHHCCCHHHHHHHCCH
ETVKKRLYATEWEQNGKPQHDMIIVGVPMSMPDGSRGAVFIYQSLEAIADATEHTKELIF
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
LAAFIAIVMTTFFAFFLSTRITAPLRKMRQAAFEVARGHFDTKVPILTNDEIGGLAMAFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHH
QMGRRLQFNINALNQEKEQLASILSSMADGVITFSREGEILITNPPAERFLQAWYFEQGN
HHCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCHHHHHHHHHCCCCC
DAETMAPLPPQVKELFARVVREEKEQSTEVTIQGRTWVILMTPLYGKTMVRGAVAVLRDM
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHHHH
TEERRLDKLRKDFIANVSHELRTPIAMLQGYSEAIIDDIAASEEEKKEMAKVIYDESLRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GRLVNDLLDLARMEAGHIELQYEQVELVPYVERVIRKFYGLAKEKQIELTAEFRDENIEI
HHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEE
AFDPDRIEQVLTNLIDNAIRHTEAGGTVRLIIERSGDGVTIHVQDSGSGIPEEDLPFVFE
EECHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHH
RFYKADKARTRGRSGTGLGLAIAKNIVETHKGRITVHSKLNEGTTFSFYLPAHGPKEM
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MMWLFRSVVGKLWFTILLLVSCVLFILTILLIKFFEEYYVQEAENDLTRLATKVAEVMHD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRDEQLARSIAWTLVDNRSKAIIVADESHYWYSPGEADLKDMPLSSIREDSDLRRVLTDQ
HHHHHHHHHHHHHEEECCCCEEEEEECCCEEECCCCCCCCCCCHHHHCCCHHHHHHHCCH
ETVKKRLYATEWEQNGKPQHDMIIVGVPMSMPDGSRGAVFIYQSLEAIADATEHTKELIF
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
LAAFIAIVMTTFFAFFLSTRITAPLRKMRQAAFEVARGHFDTKVPILTNDEIGGLAMAFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHH
QMGRRLQFNINALNQEKEQLASILSSMADGVITFSREGEILITNPPAERFLQAWYFEQGN
HHCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCHHHHHHHHHCCCCC
DAETMAPLPPQVKELFARVVREEKEQSTEVTIQGRTWVILMTPLYGKTMVRGAVAVLRDM
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHHHH
TEERRLDKLRKDFIANVSHELRTPIAMLQGYSEAIIDDIAASEEEKKEMAKVIYDESLRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GRLVNDLLDLARMEAGHIELQYEQVELVPYVERVIRKFYGLAKEKQIELTAEFRDENIEI
HHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEE
AFDPDRIEQVLTNLIDNAIRHTEAGGTVRLIIERSGDGVTIHVQDSGSGIPEEDLPFVFE
EECHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHH
RFYKADKARTRGRSGTGLGLAIAKNIVETHKGRITVHSKLNEGTTFSFYLPAHGPKEM
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]