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The map label for this gene is gpsA

Identifier: 138895797

GI number: 138895797

Start: 2282063

End: 2283094

Strand: Reverse

Name: gpsA

Synonym: GTNG_2153

Alternate gene names: 138895797

Gene position: 2283094-2282063 (Counterclockwise)

Preceding gene: 138895798

Following gene: 138895796

Centisome position: 64.31

GC content: 53.88

Gene sequence:

>1032_bases
ATGGAGAACATTACCGTATTGGGGGCAGGAAGTTGGGGGACGGCGTTGGCGCTCGTTTTAGCTGACAATGGGCACCGCGT
TCGGCTTTGGAGCCATCGGGCTGAACAAGTGAGGGAGATCAATGAACAGCGGACAAACGAAAAATATTTGCCAGGCGTCC
GCCTGCCGGAGGTTATTATCGGTTATGACGACCTTGGCGCCGCGCTTGATGGCGTTTCCATTGTTGTGCTAGCCGTGCCG
ACGAAAGCGATCCGCGAGGTACTCCAGAGAGCGCGCATGTGTTTGGCTGCGCCGATCACGATCGTTGCCGTCAGTAAAGG
AATCGAGCCGGGGACGCATAAGCGCGTGTCGGAAATTGTCACCGAAGAAATCAGTGAATGGCTAGAGGACGTCGTCGTCC
TTTCCGGGCCGAGTCATGCTGAGGAAGTGGTGCTCCGCCATCCGACGACGGTGGCAGTGTCATCGCCGAACATGGAAGCG
GCACAGTGTATTCAAGATGTATTTATGAATCACCACTATTTCCGCGTTTATACGAACCCTGACTTAGTCGGTGTCGAAGT
CGGCGGGGCGCTGAAAAACATTATTGCATTAGCCGCCGGCATCAGCGATGGGCTTGGCTATGGAGATAACGCAAAGGCGG
CTCTGATTACGCGGGGATTGGCTGAGATAGCCCGTCTTGGCTGCGCCCTCGGCGCTAACCCGTTGACGTTTGCCGGACTG
GCTGGGGTCGGCGATTTGATCGTCACGTGCACAAGTGTTCATTCCCGCAACTGGAGAGCCGGCCATATGCTTGGCCAAGG
AAAAAAGCTTGATGATGTGCTTGAAAGCATGGGGATGGTTGTTGAGGGAGTGCGGACGACAAAAGCCGCCTATGAGTTGG
CAAAAGAGCTCGGTGTGAAAATGCCGATTACCGAAGTGCTCTATGAAGTGCTGTTTGACGGAAAAAATCCGAAAGAAGCG
GTCGATTCACTCATGGCGCGCGGAAAAAAGCAGGAAATGAACGATTTAATGAACATTTTTGCCGAACAGTAA

Upstream 100 bases:

>100_bases
TTCTTCGCCGGAAGAGACTGGCCATCCAAAGGCGAAGGTGATTTGACCTCGAGCAGCGTTTTTCAGGAAAGTGACAATCG
GGCAAAGGAAGTGGGAAGCG

Downstream 100 bases:

>100_bases
CACCGAAAATAGGCGGATGGTGATACAAGTCGTCTCTGTTTTGCATACAATATGACGAACCATCATCGGCTCGAGCTTCC
GGAAGGGTATAAGGCGATGC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MENITVLGAGSWGTALALVLADNGHRVRLWSHRAEQVREINEQRTNEKYLPGVRLPEVIIGYDDLGAALDGVSIVVLAVP
TKAIREVLQRARMCLAAPITIVAVSKGIEPGTHKRVSEIVTEEISEWLEDVVVLSGPSHAEEVVLRHPTTVAVSSPNMEA
AQCIQDVFMNHHYFRVYTNPDLVGVEVGGALKNIIALAAGISDGLGYGDNAKAALITRGLAEIARLGCALGANPLTFAGL
AGVGDLIVTCTSVHSRNWRAGHMLGQGKKLDDVLESMGMVVEGVRTTKAAYELAKELGVKMPITEVLYEVLFDGKNPKEA
VDSLMARGKKQEMNDLMNIFAEQ

Sequences:

>Translated_343_residues
MENITVLGAGSWGTALALVLADNGHRVRLWSHRAEQVREINEQRTNEKYLPGVRLPEVIIGYDDLGAALDGVSIVVLAVP
TKAIREVLQRARMCLAAPITIVAVSKGIEPGTHKRVSEIVTEEISEWLEDVVVLSGPSHAEEVVLRHPTTVAVSSPNMEA
AQCIQDVFMNHHYFRVYTNPDLVGVEVGGALKNIIALAAGISDGLGYGDNAKAALITRGLAEIARLGCALGANPLTFAGL
AGVGDLIVTCTSVHSRNWRAGHMLGQGKKLDDVLESMGMVVEGVRTTKAAYELAKELGVKMPITEVLYEVLFDGKNPKEA
VDSLMARGKKQEMNDLMNIFAEQ
>Mature_343_residues
MENITVLGAGSWGTALALVLADNGHRVRLWSHRAEQVREINEQRTNEKYLPGVRLPEVIIGYDDLGAALDGVSIVVLAVP
TKAIREVLQRARMCLAAPITIVAVSKGIEPGTHKRVSEIVTEEISEWLEDVVVLSGPSHAEEVVLRHPTTVAVSSPNMEA
AQCIQDVFMNHHYFRVYTNPDLVGVEVGGALKNIIALAAGISDGLGYGDNAKAALITRGLAEIARLGCALGANPLTFAGL
AGVGDLIVTCTSVHSRNWRAGHMLGQGKKLDDVLESMGMVVEGVRTTKAAYELAKELGVKMPITEVLYEVLFDGKNPKEA
VDSLMARGKKQEMNDLMNIFAEQ

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=345, Percent_Identity=28.9855072463768, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI24307999, Length=345, Percent_Identity=28.695652173913, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1790037, Length=330, Percent_Identity=44.5454545454545, Blast_Score=293, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI32564399, Length=346, Percent_Identity=30.0578034682081, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32564403, Length=353, Percent_Identity=29.7450424929178, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI193210136, Length=353, Percent_Identity=29.7450424929178, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17507425, Length=351, Percent_Identity=28.2051282051282, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI193210134, Length=346, Percent_Identity=28.3236994219653, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324513, Length=342, Percent_Identity=29.5321637426901, Blast_Score=132, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6320181, Length=357, Percent_Identity=29.1316526610644, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17136202, Length=356, Percent_Identity=28.6516853932584, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136200, Length=344, Percent_Identity=28.7790697674419, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17136204, Length=344, Percent_Identity=28.7790697674419, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI22026922, Length=334, Percent_Identity=25.4491017964072, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI45551945, Length=237, Percent_Identity=29.957805907173, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281362270, Length=236, Percent_Identity=29.2372881355932, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24648969, Length=227, Percent_Identity=28.6343612334802, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_GEOTN (A4IQA1)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001126250.1
- ProteinModelPortal:   A4IQA1
- SMR:   A4IQA1
- STRING:   A4IQA1
- GeneID:   4967081
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_2153
- NMPDR:   fig|420246.5.peg.2060
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- PhylomeDB:   A4IQA1
- ProtClustDB:   PRK00094
- BioCyc:   GTHE420246:GTNG_2153-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36937; Mature: 36937

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 192-192 BINDING 106-106 BINDING 106-106 BINDING 140-140 BINDING 256-256 BINDING 282-282

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENITVLGAGSWGTALALVLADNGHRVRLWSHRAEQVREINEQRTNEKYLPGVRLPEVII
CCCEEEEECCCHHHEEEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEE
GYDDLGAALDGVSIVVLAVPTKAIREVLQRARMCLAAPITIVAVSKGIEPGTHKRVSEIV
CCHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCHHHHHHHHH
TEEISEWLEDVVVLSGPSHAEEVVLRHPTTVAVSSPNMEAAQCIQDVFMNHHYFRVYTNP
HHHHHHHHHHHEEECCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECC
DLVGVEVGGALKNIIALAAGISDGLGYGDNAKAALITRGLAEIARLGCALGANPLTFAGL
CEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AGVGDLIVTCTSVHSRNWRAGHMLGQGKKLDDVLESMGMVVEGVRTTKAAYELAKELGVK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MPITEVLYEVLFDGKNPKEAVDSLMARGKKQEMNDLMNIFAEQ
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MENITVLGAGSWGTALALVLADNGHRVRLWSHRAEQVREINEQRTNEKYLPGVRLPEVII
CCCEEEEECCCHHHEEEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEE
GYDDLGAALDGVSIVVLAVPTKAIREVLQRARMCLAAPITIVAVSKGIEPGTHKRVSEIV
CCHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCHHHHHHHHH
TEEISEWLEDVVVLSGPSHAEEVVLRHPTTVAVSSPNMEAAQCIQDVFMNHHYFRVYTNP
HHHHHHHHHHHEEECCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECC
DLVGVEVGGALKNIIALAAGISDGLGYGDNAKAALITRGLAEIARLGCALGANPLTFAGL
CEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AGVGDLIVTCTSVHSRNWRAGHMLGQGKKLDDVLESMGMVVEGVRTTKAAYELAKELGVK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MPITEVLYEVLFDGKNPKEAVDSLMARGKKQEMNDLMNIFAEQ
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA