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The map label for this gene is engA [H]

Identifier: 138895798

GI number: 138895798

Start: 2283351

End: 2284661

Strand: Reverse

Name: engA [H]

Synonym: GTNG_2154

Alternate gene names: 138895798

Gene position: 2284661-2283351 (Counterclockwise)

Preceding gene: 138895799

Following gene: 138895797

Centisome position: 64.35

GC content: 50.8

Gene sequence:

>1311_bases
ATGGCAAATCCAGTCGTGGCCATTGTCGGCCGTCCGAATGTGGGGAAATCAACCATTTTCAACCGCATCGTCGGAGAACG
CATTTCCATCGTTGAGGATGTACCGGGGGTGACGCGCGACCGCATTTACAGCAGCGCCGAATGGTTGAACCATTCATTTT
ATTTAATTGACACGGGAGGCATTGACATCGGTGATGAGCCGCTGCTTGTGCAAATTCGTCAGCAGGCAGAAATCGCCATC
GATGAGGCGGACGTCATCATCTTTATGACGAACGGCCGTGACGGTGTGACAGCCGCTGATGAAGAAGTGGCGAAACTGCT
GCGCCGGTCGAATAAGCCAGTCGTGCTCGCCGTGAATAAAATCGATAACCCGGAGATGCGTGATTTGATTTACGATTTTT
ACGCTCTTGGTTTTGGCGAGCCGTACCCCATTTCTGGGGCGCACGGAACGGGACTTGGCGATTTGCTTGACGCCGTTGCT
CGCCATTTTCCGAAAGATCACGGCCAAGAATATGAGGAAGACGTGATTAAGTTTTGCCTCATCGGCCGGCCAAACGTCGG
TAAATCGTCGCTGGTTAACGCCATTTTAGGGGAAGAACGAGTGATTGTCAGCGACATCGCCGGCACGACGAGGGACGCTG
TGGACACCTCGTTTGTCCGCGAAGGTCAGAAATATGTTATTATCGATACAGCAGGAATGCGCAAACGAGGAAAAATTTAC
GAAAGCACGGAGAAATACAGTGTGTTGCGCGCGCTAAGAGCCATTGAGCGCTCGGATGTCGTGCTCGTTGTCCTGAACGC
AGAGGAAGGGATTATTGAACAGGATAAAAAAATCGCCGGGTATGCACATGAGGCAGGGCGTGGCGTCATTCTCGTCGTCA
ATAAATGGGATGCCGTCGAAAAAGACGATAAAACAATGGTGGAATTTGAGCGGAAAATTCGCGATCATTTTCCATTTTTG
GACTATGCACCGATTTTATTTGTGTCGGCGAAGACAAAACAGCGGCTTCATAAGCTGTTGCCGCTCGTGCAACTCGTAAG
TGACAACCACGCGATGCGCGTTCAAACGAACGTGCTCAATGAAGTCATTATGGATGCGGTGGCGATGAACCCGACGCCGA
CGCATAACGGTCGGCGCCTAAAAATTTATTATATGACGCAAGTCGCCGTCAAACCGCCGACGTTCGTCGCTTTTGTCAAT
GATCCGGAACTCATGCACTTTTCATACGAACGATTTTTGGAAAATCGCATCCGCGACGCGTTCGGCTTCGAAGGTACACC
GATCAAAATCATTGCCCGCCCGCGGAAATAA

Upstream 100 bases:

>100_bases
GAGCGTCAGTACGCTTAACGGTGGTGAACCGATGCCCTAGGAGCAGGGCGTTTTTTTTCAAGAGCAAAACGATGTAAAAA
TGAGGATAAAGGGTGGTAGC

Downstream 100 bases:

>100_bases
GAAAAGCGGCGGCGCCGAGACCAGCTCTCGAAGTCAAACATTCTCCGGCCACAGGGGGGCTTGCACCCCGAGGGGGAGGT
TATTTGGTGGAAGAGAGCTA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MANPVVAIVGRPNVGKSTIFNRIVGERISIVEDVPGVTRDRIYSSAEWLNHSFYLIDTGGIDIGDEPLLVQIRQQAEIAI
DEADVIIFMTNGRDGVTAADEEVAKLLRRSNKPVVLAVNKIDNPEMRDLIYDFYALGFGEPYPISGAHGTGLGDLLDAVA
RHFPKDHGQEYEEDVIKFCLIGRPNVGKSSLVNAILGEERVIVSDIAGTTRDAVDTSFVREGQKYVIIDTAGMRKRGKIY
ESTEKYSVLRALRAIERSDVVLVVLNAEEGIIEQDKKIAGYAHEAGRGVILVVNKWDAVEKDDKTMVEFERKIRDHFPFL
DYAPILFVSAKTKQRLHKLLPLVQLVSDNHAMRVQTNVLNEVIMDAVAMNPTPTHNGRRLKIYYMTQVAVKPPTFVAFVN
DPELMHFSYERFLENRIRDAFGFEGTPIKIIARPRK

Sequences:

>Translated_436_residues
MANPVVAIVGRPNVGKSTIFNRIVGERISIVEDVPGVTRDRIYSSAEWLNHSFYLIDTGGIDIGDEPLLVQIRQQAEIAI
DEADVIIFMTNGRDGVTAADEEVAKLLRRSNKPVVLAVNKIDNPEMRDLIYDFYALGFGEPYPISGAHGTGLGDLLDAVA
RHFPKDHGQEYEEDVIKFCLIGRPNVGKSSLVNAILGEERVIVSDIAGTTRDAVDTSFVREGQKYVIIDTAGMRKRGKIY
ESTEKYSVLRALRAIERSDVVLVVLNAEEGIIEQDKKIAGYAHEAGRGVILVVNKWDAVEKDDKTMVEFERKIRDHFPFL
DYAPILFVSAKTKQRLHKLLPLVQLVSDNHAMRVQTNVLNEVIMDAVAMNPTPTHNGRRLKIYYMTQVAVKPPTFVAFVN
DPELMHFSYERFLENRIRDAFGFEGTPIKIIARPRK
>Mature_435_residues
ANPVVAIVGRPNVGKSTIFNRIVGERISIVEDVPGVTRDRIYSSAEWLNHSFYLIDTGGIDIGDEPLLVQIRQQAEIAID
EADVIIFMTNGRDGVTAADEEVAKLLRRSNKPVVLAVNKIDNPEMRDLIYDFYALGFGEPYPISGAHGTGLGDLLDAVAR
HFPKDHGQEYEEDVIKFCLIGRPNVGKSSLVNAILGEERVIVSDIAGTTRDAVDTSFVREGQKYVIIDTAGMRKRGKIYE
STEKYSVLRALRAIERSDVVLVVLNAEEGIIEQDKKIAGYAHEAGRGVILVVNKWDAVEKDDKTMVEFERKIRDHFPFLD
YAPILFVSAKTKQRLHKLLPLVQLVSDNHAMRVQTNVLNEVIMDAVAMNPTPTHNGRRLKIYYMTQVAVKPPTFVAFVND
PELMHFSYERFLENRIRDAFGFEGTPIKIIARPRK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=40.8791208791209, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1788919, Length=177, Percent_Identity=33.8983050847458, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=43.4782608695652, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=189, Percent_Identity=33.8624338624339, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45550813, Length=188, Percent_Identity=30.3191489361702, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48946; Mature: 48815

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPVVAIVGRPNVGKSTIFNRIVGERISIVEDVPGVTRDRIYSSAEWLNHSFYLIDTGG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCC
IDIGDEPLLVQIRQQAEIAIDEADVIIFMTNGRDGVTAADEEVAKLLRRSNKPVVLAVNK
CCCCCCCCEEEEECCCCEEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEC
IDNPEMRDLIYDFYALGFGEPYPISGAHGTGLGDLLDAVARHFPKDHGQEYEEDVIKFCL
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
IGRPNVGKSSLVNAILGEERVIVSDIAGTTRDAVDTSFVREGQKYVIIDTAGMRKRGKIY
CCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCH
ESTEKYSVLRALRAIERSDVVLVVLNAEEGIIEQDKKIAGYAHEAGRGVILVVNKWDAVE
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHCCCHHHCCHHHCCCEEEEEEECCCCCC
KDDKTMVEFERKIRDHFPFLDYAPILFVSAKTKQRLHKLLPLVQLVSDNHAMRVQTNVLN
CCCHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
EVIMDAVAMNPTPTHNGRRLKIYYMTQVAVKPPTFVAFVNDPELMHFSYERFLENRIRDA
HHHHHHHHCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHH
FGFEGTPIKIIARPRK
HCCCCCCEEEEECCCC
>Mature Secondary Structure 
ANPVVAIVGRPNVGKSTIFNRIVGERISIVEDVPGVTRDRIYSSAEWLNHSFYLIDTGG
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCC
IDIGDEPLLVQIRQQAEIAIDEADVIIFMTNGRDGVTAADEEVAKLLRRSNKPVVLAVNK
CCCCCCCCEEEEECCCCEEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEC
IDNPEMRDLIYDFYALGFGEPYPISGAHGTGLGDLLDAVARHFPKDHGQEYEEDVIKFCL
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
IGRPNVGKSSLVNAILGEERVIVSDIAGTTRDAVDTSFVREGQKYVIIDTAGMRKRGKIY
CCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCH
ESTEKYSVLRALRAIERSDVVLVVLNAEEGIIEQDKKIAGYAHEAGRGVILVVNKWDAVE
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHCCCHHHCCHHHCCCEEEEEEECCCCCC
KDDKTMVEFERKIRDHFPFLDYAPILFVSAKTKQRLHKLLPLVQLVSDNHAMRVQTNVLN
CCCHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
EVIMDAVAMNPTPTHNGRRLKIYYMTQVAVKPPTFVAFVNDPELMHFSYERFLENRIRDA
HHHHHHHHCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHH
FGFEGTPIKIIARPRK
HCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA