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The map label for this gene is aroA

Identifier: 138895774

GI number: 138895774

Start: 2260890

End: 2262188

Strand: Reverse

Name: aroA

Synonym: GTNG_2130

Alternate gene names: 138895774

Gene position: 2262188-2260890 (Counterclockwise)

Preceding gene: 138895775

Following gene: 138895773

Centisome position: 63.72

GC content: 55.5

Gene sequence:

>1299_bases
GTGGAGGGATGTTGCATGCAGCTGCCAACGAACGTATCCTCGCTTCGGGGAACGATTGAGGTGCCCGGCGACAAATCGAT
TTCCCATCGCGCTGTCATGCTCGGGGCGCTCGCTTCCGGACGGACGGTGATCGATCATTTTTTGCCTGGTGCAGATTGTT
TAAGTACAATTGACTGTTTCCGCAAACTTGGTGTCGACATTCATCAAGACGGGACGAACGTCATCGTCGAAGGGGCAGGG
TCCGGAGGGCTTCGTGAGCCGGCCGCCGTGCTTGATGTCGGCAATTCCGGCACGACGGCGCGCCTTTTGCTTGGCATTTT
GGCCGGTCAGCCGTTTCATGCTTGCCTTGTTGGCGACGAGTCCATTGCCCAACGGCCGATGGCGCGGGTGACGAAGCCGC
TCCGTGAGATGGGAGCACACATTGACGGGCGTGATGACGGAAACTATACCCCGCTTGCGATCCGCGGCGGCGCGCTTCGC
CCGCTCCGCTATACCTCACCGGTGGCGAGCGCTCAAGTGAAGTCGGCGATTTTGCTTGCCGGTTTGTTTACTGACGGAGT
GACGTCCGTCACTGAGCCGCACCGCTCGCGCGACCATACCGAACGAATGATTCGGTTGTTTGGCGGCGAAGTGAATGTTG
ACGGCCTAACCGTCTCTATTGCCGGTCCGCAGTCCTTACGCGGGACGCACATTTACGTTCCTGGCGACATTTCATCGGCT
GCTTTTTTCCTCGTCGCTGGCGCGATTGTGCCAAACAGTGAAATTACGCTGAAAAACGTTGGCTTAAATCCGACAAGAAC
AGGCATCATCGATGTGCTCGAGCGAATGGGAGCCGACATTACGATTGACCATATCCGCAATGAGGAAACGGAGCCGATCG
GCGATATTACAATCCGCACATCGACGCTTCACGCCATTGAAATTGGTGGTGATATCATTCCAAGGCTGATTGATGAAATT
CCAATCATTGCCTTGTTGGCGACGCAAGCGGAAGGGACAACTATCATTAAAGATGCCAGTGAGTTGAAAGTAAAAGAAAC
GAATCGGATCGATACAGTCGTTGCCGAGCTGAAAAAGTTTGGCGCTGATATTGAAGCAACCGACGATGGCATGATCATTC
GCGGCAAAACGGCGCTTTATGCCGACGGGATTGTCGTCGACAGCCACGGTGATCATCGGATCGGGATGATGCTGGCCATC
GCTGCGTGCTGCGCGAAAGGAACGGCTCGCCTTGAGCGTCCGGAAGCGGTCGCCGTCTCCTATCCGGCCTTTTTTGCCGA
TCTTCGTTCTTTGCTGTAG

Upstream 100 bases:

>100_bases
TCCGCCTTAGCTTCCAAAGCGAAGATGATCGGGCGCGGGCGAAAGCGTGCCTCGCCAAACATACGAATTTTGCGACATAT
GAAGGGTAGCAAGAAAAACA

Downstream 100 bases:

>100_bases
CCTCAAGCGCCCTCGCCCCAAGTGGGCGAGGGGCATATTTTGCTTTGATCATTCATATGTTGTCAATAAGAGGGATGGCT
TCTCCTTACTTTTTGAAAGC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MEGCCMQLPTNVSSLRGTIEVPGDKSISHRAVMLGALASGRTVIDHFLPGADCLSTIDCFRKLGVDIHQDGTNVIVEGAG
SGGLREPAAVLDVGNSGTTARLLLGILAGQPFHACLVGDESIAQRPMARVTKPLREMGAHIDGRDDGNYTPLAIRGGALR
PLRYTSPVASAQVKSAILLAGLFTDGVTSVTEPHRSRDHTERMIRLFGGEVNVDGLTVSIAGPQSLRGTHIYVPGDISSA
AFFLVAGAIVPNSEITLKNVGLNPTRTGIIDVLERMGADITIDHIRNEETEPIGDITIRTSTLHAIEIGGDIIPRLIDEI
PIIALLATQAEGTTIIKDASELKVKETNRIDTVVAELKKFGADIEATDDGMIIRGKTALYADGIVVDSHGDHRIGMMLAI
AACCAKGTARLERPEAVAVSYPAFFADLRSLL

Sequences:

>Translated_432_residues
MEGCCMQLPTNVSSLRGTIEVPGDKSISHRAVMLGALASGRTVIDHFLPGADCLSTIDCFRKLGVDIHQDGTNVIVEGAG
SGGLREPAAVLDVGNSGTTARLLLGILAGQPFHACLVGDESIAQRPMARVTKPLREMGAHIDGRDDGNYTPLAIRGGALR
PLRYTSPVASAQVKSAILLAGLFTDGVTSVTEPHRSRDHTERMIRLFGGEVNVDGLTVSIAGPQSLRGTHIYVPGDISSA
AFFLVAGAIVPNSEITLKNVGLNPTRTGIIDVLERMGADITIDHIRNEETEPIGDITIRTSTLHAIEIGGDIIPRLIDEI
PIIALLATQAEGTTIIKDASELKVKETNRIDTVVAELKKFGADIEATDDGMIIRGKTALYADGIVVDSHGDHRIGMMLAI
AACCAKGTARLERPEAVAVSYPAFFADLRSLL
>Mature_432_residues
MEGCCMQLPTNVSSLRGTIEVPGDKSISHRAVMLGALASGRTVIDHFLPGADCLSTIDCFRKLGVDIHQDGTNVIVEGAG
SGGLREPAAVLDVGNSGTTARLLLGILAGQPFHACLVGDESIAQRPMARVTKPLREMGAHIDGRDDGNYTPLAIRGGALR
PLRYTSPVASAQVKSAILLAGLFTDGVTSVTEPHRSRDHTERMIRLFGGEVNVDGLTVSIAGPQSLRGTHIYVPGDISSA
AFFLVAGAIVPNSEITLKNVGLNPTRTGIIDVLERMGADITIDHIRNEETEPIGDITIRTSTLHAIEIGGDIIPRLIDEI
PIIALLATQAEGTTIIKDASELKVKETNRIDTVVAELKKFGADIEATDDGMIIRGKTALYADGIVVDSHGDHRIGMMLAI
AACCAKGTARLERPEAVAVSYPAFFADLRSLL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=444, Percent_Identity=30.4054054054054, Blast_Score=132, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6320332, Length=431, Percent_Identity=25.5220417633411, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_GEOTN (A4IQ78)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001126227.1
- ProteinModelPortal:   A4IQ78
- SMR:   A4IQ78
- STRING:   A4IQ78
- GeneID:   4967058
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_2130
- NMPDR:   fig|420246.5.peg.2037
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- PhylomeDB:   A4IQ78
- ProtClustDB:   PRK02427
- BioCyc:   GTHE420246:GTNG_2130-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45729; Mature: 45729

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGCCMQLPTNVSSLRGTIEVPGDKSISHRAVMLGALASGRTVIDHFLPGADCLSTIDCF
CCCCCCCCCCCHHHCCCEEECCCCCCCCHHHHEEEHHHCCCHHHHHHCCCHHHHHHHHHH
RKLGVDIHQDGTNVIVEGAGSGGLREPAAVLDVGNSGTTARLLLGILAGQPFHACLVGDE
HHHCCEEECCCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCH
SIAQRPMARVTKPLREMGAHIDGRDDGNYTPLAIRGGALRPLRYTSPVASAQVKSAILLA
HHHHCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
GLFTDGVTSVTEPHRSRDHTERMIRLFGGEVNVDGLTVSIAGPQSLRGTHIYVPGDISSA
HHHHCCCHHHCCCCCCHHHHHHHHHHHCCEEEECCEEEEECCCCCCCCCEEEECCCCCHH
AFFLVAGAIVPNSEITLKNVGLNPTRTGIIDVLERMGADITIDHIRNEETEPIGDITIRT
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEE
STLHAIEIGGDIIPRLIDEIPIIALLATQAEGTTIIKDASELKVKETNRIDTVVAELKKF
CEEEEEECCCHHHHHHHHHCCEEEEEEECCCCCEEEECHHHCEECCCCHHHHHHHHHHHH
GADIEATDDGMIIRGKTALYADGIVVDSHGDHRIGMMLAIAACCAKGTARLERPEAVAVS
CCCCEECCCCEEEECCCEEEECCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEE
YPAFFADLRSLL
CHHHHHHHHHHC
>Mature Secondary Structure
MEGCCMQLPTNVSSLRGTIEVPGDKSISHRAVMLGALASGRTVIDHFLPGADCLSTIDCF
CCCCCCCCCCCHHHCCCEEECCCCCCCCHHHHEEEHHHCCCHHHHHHCCCHHHHHHHHHH
RKLGVDIHQDGTNVIVEGAGSGGLREPAAVLDVGNSGTTARLLLGILAGQPFHACLVGDE
HHHCCEEECCCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCH
SIAQRPMARVTKPLREMGAHIDGRDDGNYTPLAIRGGALRPLRYTSPVASAQVKSAILLA
HHHHCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
GLFTDGVTSVTEPHRSRDHTERMIRLFGGEVNVDGLTVSIAGPQSLRGTHIYVPGDISSA
HHHHCCCHHHCCCCCCHHHHHHHHHHHCCEEEECCEEEEECCCCCCCCCEEEECCCCCHH
AFFLVAGAIVPNSEITLKNVGLNPTRTGIIDVLERMGADITIDHIRNEETEPIGDITIRT
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEE
STLHAIEIGGDIIPRLIDEIPIIALLATQAEGTTIIKDASELKVKETNRIDTVVAELKKF
CEEEEEECCCHHHHHHHHHCCEEEEEEECCCCCEEEECHHHCEECCCCHHHHHHHHHHHH
GADIEATDDGMIIRGKTALYADGIVVDSHGDHRIGMMLAIAACCAKGTARLERPEAVAVS
CCCCEECCCCEEEECCCEEEECCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEE
YPAFFADLRSLL
CHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA