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The map label for this gene is aspC [H]

Identifier: 138895751

GI number: 138895751

Start: 2240347

End: 2241528

Strand: Reverse

Name: aspC [H]

Synonym: GTNG_2107

Alternate gene names: 138895751

Gene position: 2241528-2240347 (Counterclockwise)

Preceding gene: 138895752

Following gene: 138895750

Centisome position: 63.14

GC content: 54.15

Gene sequence:

>1182_bases
ATGAAATTGGCAAAACGGGTGGCGTCGCTGACGCCATCGGCGACTTTGGCCATTACGGCGAAAGCAAAAGAACTAAAAGC
GGCCGGGCATGACGTGATTGGTCTCGGAGCTGGCGAACCGGATTTCAACACGCCACAGCACATTCTTGATGCCGCCATCA
AGGCAATGAACGAAGGACATACGAAATATACACCATCGGGCGGTTTGCCGGCGTTAAAGGAGGAAATTATAAAAAAATTC
GCCCGCGACCAAGGCTTGGATTATGAGCCGGCTGAAGTGATTGTATGCGTCGGAGCGAAGCACGCCCTTTACACGCTGTT
CCAAGTATTGCTCGATGAAGGCGACGAAGTGATCATTCCGACGCCATACTGGGTGAGCTATCCGGAACAAGTGAAACTGG
CGGGCGGTGTTCCGGTTTACGTCGAAGGGCTTGAACAAAATCATTTTAAAATTACGCCGGAGCAGCTGAAACAGGCAATC
ACGCCGCGGACGAAAGCGGTTATCATCAACTCGCCGAGCAACCCGACTGGCATGATTTATACAGCCGAAGAGTTGAAGGC
GCTTGGTGAGGTGTGCCTAGCGCATGGTGTATTGATCGTGTCAGATGAAATTTATGAAAAATTGACTTACGGCGGGGCGA
AGCATGTGTCCATCGCTGAGTTGTCGCCGGAGCTGAAGGCGCAGACAGTCATCATTAACGGCGTGTCAAAGTCGCATTCG
ATGACGGGCTGGCGCATTGGTTATGCGGCGGGGCCGAAAGATATTATTAAGGCAATGACAGATTTGGCGAGCCACAGCAC
GTCCAACCCGACGTCAATCGCCCAATACGCGGCCATCGCTGCTTACAGCGGGCCGCAGGAGCCGGTCGAACAAATGCGCC
AAGCGTTTGAACAACGGCTCAATATCATTTACGACAAGCTCGTGCAAATTCCAGGATTCACGTGCGTTAAGCCACAAGGG
GCGTTTTATTTGTTCCCGAACGCCCGCGAAGCGGCTGCAATGGCCGGCTGCCGCACGGTCGACGAGTTCGTCGCTGCCTT
GTTGGAGGAAGCGAAAGTCGCGCTTGTGCCCGGCTCTGGGTTTGGAGCGCCGGATAACGTTCGCTTGTCATACGCGACAT
CGCTCGATGCACTGGAAACCGCCGTGGAACGCATCCACCGGTTTATGGAAGCGCGCGCTTAA

Upstream 100 bases:

>100_bases
TGCAGAAGGAAGGTATTCGTTTTATTACCTCCATTTTGCCGATGGTTCATTCTTAAAGAGGTACAGTTTTCAACGTTGAG
CATATGAGGGGGAAGAAACG

Downstream 100 bases:

>100_bases
CAAGCGGCGGCTTTGCCCAAAGCAAAGCCGCTTTTTCCGCGCCCGCTGCAGCGGCGGTGATTTCGCGAAAATCAGCCGGA
TGCATGATTTTTTAGCGGTT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKLAKRVASLTPSATLAITAKAKELKAAGHDVIGLGAGEPDFNTPQHILDAAIKAMNEGHTKYTPSGGLPALKEEIIKKF
ARDQGLDYEPAEVIVCVGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGVPVYVEGLEQNHFKITPEQLKQAI
TPRTKAVIINSPSNPTGMIYTAEELKALGEVCLAHGVLIVSDEIYEKLTYGGAKHVSIAELSPELKAQTVIINGVSKSHS
MTGWRIGYAAGPKDIIKAMTDLASHSTSNPTSIAQYAAIAAYSGPQEPVEQMRQAFEQRLNIIYDKLVQIPGFTCVKPQG
AFYLFPNAREAAAMAGCRTVDEFVAALLEEAKVALVPGSGFGAPDNVRLSYATSLDALETAVERIHRFMEARA

Sequences:

>Translated_393_residues
MKLAKRVASLTPSATLAITAKAKELKAAGHDVIGLGAGEPDFNTPQHILDAAIKAMNEGHTKYTPSGGLPALKEEIIKKF
ARDQGLDYEPAEVIVCVGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGVPVYVEGLEQNHFKITPEQLKQAI
TPRTKAVIINSPSNPTGMIYTAEELKALGEVCLAHGVLIVSDEIYEKLTYGGAKHVSIAELSPELKAQTVIINGVSKSHS
MTGWRIGYAAGPKDIIKAMTDLASHSTSNPTSIAQYAAIAAYSGPQEPVEQMRQAFEQRLNIIYDKLVQIPGFTCVKPQG
AFYLFPNAREAAAMAGCRTVDEFVAALLEEAKVALVPGSGFGAPDNVRLSYATSLDALETAVERIHRFMEARA
>Mature_393_residues
MKLAKRVASLTPSATLAITAKAKELKAAGHDVIGLGAGEPDFNTPQHILDAAIKAMNEGHTKYTPSGGLPALKEEIIKKF
ARDQGLDYEPAEVIVCVGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGVPVYVEGLEQNHFKITPEQLKQAI
TPRTKAVIINSPSNPTGMIYTAEELKALGEVCLAHGVLIVSDEIYEKLTYGGAKHVSIAELSPELKAQTVIINGVSKSHS
MTGWRIGYAAGPKDIIKAMTDLASHSTSNPTSIAQYAAIAAYSGPQEPVEQMRQAFEQRLNIIYDKLVQIPGFTCVKPQG
AFYLFPNAREAAAMAGCRTVDEFVAALLEEAKVALVPGSGFGAPDNVRLSYATSLDALETAVERIHRFMEARA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=364, Percent_Identity=31.8681318681319, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI169881279, Length=364, Percent_Identity=31.8681318681319, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI56713254, Length=416, Percent_Identity=26.9230769230769, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI56713256, Length=416, Percent_Identity=26.9230769230769, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI169881281, Length=361, Percent_Identity=27.1468144044321, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI4507369, Length=386, Percent_Identity=25.1295336787565, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI19263340, Length=368, Percent_Identity=23.6413043478261, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=23.6413043478261, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4885351, Length=343, Percent_Identity=25.0728862973761, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI187936925, Length=204, Percent_Identity=28.4313725490196, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI14211921, Length=204, Percent_Identity=28.4313725490196, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788627, Length=385, Percent_Identity=30.1298701298701, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1786816, Length=371, Percent_Identity=28.0323450134771, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1788722, Length=388, Percent_Identity=29.8969072164948, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787909, Length=234, Percent_Identity=25.6410256410256, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693159, Length=112, Percent_Identity=33.9285714285714, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=423, Percent_Identity=29.7872340425532, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71994472, Length=423, Percent_Identity=29.7872340425532, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17567369, Length=401, Percent_Identity=27.1820448877805, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=26.7567567567568, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71981209, Length=365, Percent_Identity=21.6438356164384, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=400, Percent_Identity=30, Blast_Score=156, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6320317, Length=341, Percent_Identity=25.8064516129032, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323118, Length=345, Percent_Identity=27.8260869565217, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573069, Length=418, Percent_Identity=26.555023923445, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24646114, Length=418, Percent_Identity=26.555023923445, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28573067, Length=418, Percent_Identity=26.555023923445, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28573065, Length=418, Percent_Identity=26.555023923445, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=24.869109947644, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI45551451, Length=395, Percent_Identity=24.3037974683544, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641770, Length=395, Percent_Identity=24.3037974683544, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641760, Length=395, Percent_Identity=24.3037974683544, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641768, Length=395, Percent_Identity=24.3037974683544, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641766, Length=395, Percent_Identity=24.3037974683544, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641764, Length=395, Percent_Identity=24.3037974683544, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42344; Mature: 42344

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAKRVASLTPSATLAITAKAKELKAAGHDVIGLGAGEPDFNTPQHILDAAIKAMNEGH
CCHHHHHHHCCCCCEEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPSGGLPALKEEIIKKFARDQGLDYEPAEVIVCVGAKHALYTLFQVLLDEGDEVIIP
CEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEC
TPYWVSYPEQVKLAGGVPVYVEGLEQNHFKITPEQLKQAITPRTKAVIINSPSNPTGMIY
CCCCCCCCCCEEECCCCEEEEECCCCCCEEECHHHHHHHHCCCCEEEEEECCCCCCEEEE
TAEELKALGEVCLAHGVLIVSDEIYEKLTYGGAKHVSIAELSPELKAQTVIINGVSKSHS
EHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCEEHHHCCCCCCEEEEEEECCCCCCC
MTGWRIGYAAGPKDIIKAMTDLASHSTSNPTSIAQYAAIAAYSGPQEPVEQMRQAFEQRL
CCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NIIYDKLVQIPGFTCVKPQGAFYLFPNAREAAAMAGCRTVDEFVAALLEEAKVALVPGSG
HHHHHHHHHCCCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
FGAPDNVRLSYATSLDALETAVERIHRFMEARA
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLAKRVASLTPSATLAITAKAKELKAAGHDVIGLGAGEPDFNTPQHILDAAIKAMNEGH
CCHHHHHHHCCCCCEEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPSGGLPALKEEIIKKFARDQGLDYEPAEVIVCVGAKHALYTLFQVLLDEGDEVIIP
CEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEC
TPYWVSYPEQVKLAGGVPVYVEGLEQNHFKITPEQLKQAITPRTKAVIINSPSNPTGMIY
CCCCCCCCCCEEECCCCEEEEECCCCCCEEECHHHHHHHHCCCCEEEEEECCCCCCEEEE
TAEELKALGEVCLAHGVLIVSDEIYEKLTYGGAKHVSIAELSPELKAQTVIINGVSKSHS
EHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCEEHHHCCCCCCEEEEEEECCCCCCC
MTGWRIGYAAGPKDIIKAMTDLASHSTSNPTSIAQYAAIAAYSGPQEPVEQMRQAFEQRL
CCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NIIYDKLVQIPGFTCVKPQGAFYLFPNAREAAAMAGCRTVDEFVAALLEEAKVALVPGSG
HHHHHHHHHCCCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
FGAPDNVRLSYATSLDALETAVERIHRFMEARA
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8837436 [H]